국내 건강보험 청구자료의 활용 촉진을 위한 현안 및 개선방안

최남경,김희진,김동욱,김명규,김미숙,배승진,정선영,김예지,김정아,박수빈,조해린,신애선,신주영,안성복,안정훈,양보람,원희현,이승미,이희언,이중엽 대한약물역학위해관리학회 2024 약물역학위해관리학회지 Vol.16 No.1

While health insurance claims data in Korea have the potential as evidence for drug regulatory decision-making, its effective utilization remains limited. This study aims to identify the challenges encountered by researchers in utilizing claims data and discuss improvement strategies. We summarized practical difficulties encountered by researchers who have experience using claims data from the National Health Insurance Service and the Health Insurance Review and Assessment Service. Challenges encountered by researchers included difficulties in acquiring drug data, delays in data provision, limited provision of information on specific conditions, drugs, and treatments, small data capacity, short data usage periods, and spatiotemporal considerations when accessing data. To maximize the utility of claims data in drug regulatory decision-making, continuous communication between researchers and data providers is necessary for addressing these challenges. (PeRM 2024;16:1-10)

한국노인약물역학코호트에서 폐암 발생률, 사망률 및 생존율, 1994-1998

최남경,윤경은,허대석,김윤이,이승미,박병주 한국역학회 2002 Epidemiology and Health Vol.24 No.2

Purpose : This study was conducted to estimate incidence, mortality and survival rate of lung cancer in the elderly people in Korea. Methods : Study population was Korean Elderly Phamacoepidemiologic Cohort (KEPEC). The lung cancer incidence cases were detected from three different sources, medical utilization database of the Korea Medical Insurance Corporation (KMIC), the database from the National Cancer Registry, and the database from the Regional Cancer Registry. The hospital survey to confirm the final diagnosis of the potential cases was conducted. A specialist on lung cancer reviewed the abstracted data to confirm the final diagnoses. The lung cancer death cases were detected from the mortality database at National Statistical Office. Incidence rate, survival rate and mortality rate of lung cancer and their 95% confidence intervals were estimated with SAS Window ver.8.1. Results : There were 213 confirmed lung cancer cases in KEPEC between Jan. 1994 and Dec. 1998. Age-standardized incidence rate of lung cancer to the Korean population was estimated to be 316.9 per 100,000 person-years in male and 65.2 per 100,000 person-years in female. Age-standardized mortality rate of lung cancer to the Korean population was estimated to be 342.3 per 100,000 person-years in male and 84.8 per 100,000 person-years in female. One years survival rate was 17% in male and 11% in female. Two year survival rate was 2% in male and 4% in female. Conclusion : Age-standardized incidence rate, age-standardized mortality rate and survival rate of lung cancer in the elderly Korean may be useful for further study and making health policy for managing lung cancer in the elderly.

임상시험 연구자를 위한 교육 및 자격인증 프로그램에 관한 설문조사

최남경 대한임상약리학회 2005 Translational and Clinical Pharmacology Vol.13 No.2

Background: Specialized and continuous educational program is needed for investigators. A questionnaire survey was performed to examine current status of educational experience, preferred forms and contents for educational program and certification system, prior to development of investigator educational and certification programs. Methods: Developed questionnaires were posted to 738 clinical investigators in October 2005. The questionnaire consisted of questions about demographics, clinical trials experience, educational program experience, and preferred educational and certification program. The analysis included investigators who participated in at least one clinical trial within past 3 years. Results: A total of 122 subjects was responded to the survey (16.5% response rate). Among the total subject 96 (78.7%) had participated in at least one clinical trial within past 3 years and all analyses included only the 96 subjects. Forty three percent had experience to be educated related to clinical trials and over ninety percent had intention to participate in the educational program for investigators. Preferred educational contents for clinical investigators both for basic and advanced course were subject protection and consent, regulation, clinical trial design, statistics and data management, protocol development, randomization, and blinding. Eighty three percent of subjects preferred short-term intensive course with 3 days or less. Investigators participated in any education program once or more agreed to necessity of certification system more than non-participants (p=0.002). University, research center or academic society was preferred for Institution for certification (55.8%). Conclusion: Educational program for investigators specialized by diverse time period and level has tobe developed. Certification for investigators seems to be necessary to improve research capacity and to standardize quality continuously.

요양급여심사기준 변경에 따른 COX-2 선택 억제제 약물처방양상

최남경 대한임상약리학회 2004 Translational and Clinical Pharmacology Vol.12 No.1

Background : Recently marketed Cyclooxygenase 2(COX-2) selective inhibitors promoted as safer nonsteroidal anti-inflammatory drugs(NSAIDs) regarding gastric toxicity. Korea National Health Insurance Review Agency(HIRA) revised claims review criteria of COX-2 selective inhibitors in June 2001 and October 2001. This study was performed to assess the prescribing pattern of COX-2 selective inhibitors across the change in claims review criteria. Methods : This study was a retrospective drug utilization review study from August 1, 2000 through March 31, 2002. Data on drug prescriptions were obtained from the Health Insurance Claims Database which included the whole outpatient clinics prescription data in Busan metropolitan city, Korea. Demographic information such as age, sex and prescription information including brand name, prescription date, daily dose, duration and diagnosis were collected. COX-2 selective inhibitor prescriptions were screened and analyzed by the age, sex, and type of hospitals using SAS Windows ver. 8.1. Results : Total COX-2 selective inhibitor prescription frequency was 115,473 during this period. Among total prescriptions 69.2% was prescribed at primary ambulatory units and 79.1% was used for female patients. The prescription frequency of COX-2 selective inhibitor was significantly decreased from June 2001 to October 2001 (p<0.001). Conclusion : COX-2 selective inhibitors prescription frequency shows sharp decline by change of claims review criteria. This result implies administrative policy such as claims review criteria can substantially influence drug prescription patterns, specially which has its alternatives.

건강보험심사평가원 자료를 활용한 보건사회약학연구

최남경 한국보건사회약료경영학회 2015 한국보건사회약료경영학회지 Vol.4 No.1

BACKGROUNDS Health insurance administrative databases are important sources of information in finding health-related evidence. The objective of this study was to introduce the Korean Health Insurance Review and Assessment Service (HIRA) claims database to perform public health and social pharmacy studies. METHODS This article introduces the contents and characteristics of the HIRA data, describes the data acquisition procedures, provides examples of studies carried out using the data, and discusses several aspects that requires attention in those studies. RESULTS The HIRA claims database contains information on all claims including patients’ diagnoses, treatments, procedures, and prescription drugs for approximately 50 million Koreans. This database can be used for the following analyses: estimation of incidence or prevalence for a variety of specific disease, description of the utilization of health care resources and services, and verification of hypotheses about the health outcomes. This database has advantages including low cost, ease of patient follow-up over long time periods, and absence of reporting bias. There are several limitations of using this database including uncertain or low validity of disease diagnoses, potential discrepancies between physician’s prescriptions and patient’s actual medication intake, and lack of laboratory results and health-related behavioral information. CONCLUSION The HIRA data provide tremendous opportunities to perform large-scale quantitative analyses in the fields of public health and social pharmacy. A better understanding of prescribing practice, health policy, and data structures allows the researchers to use the claim database appropriately.

딥러닝을 이용한 박판 빔프레임 모델의 조인트 스프링 강성 예측

Ngoc Linh Nguyen,진아현(Ah-hyeon Jin),강남우(Namwoo Kang),장강원(Gang-Won Jang) 대한기계학회 2020 대한기계학회 춘추학술대회 Vol.2020 No.12

취업준비요령

최남경 고신대학교 학생생활취업정보센타 1998 學生生活硏究 Vol.12 No.-

일본 신약 시판직후조사 제도

최남경 대한임상약리학회 2003 Translational and Clinical Pharmacology Vol.11 No.1

부산지역 의원급 외래 노인 골관절염환자의 비스테로이드소염제 사용양상평가

최남경,김윤이,이승미,박병주,Choi, Nam-Kyong,Kim, Yoon-I,Lee, Seung-Mi,Park, Byung-Joo 대한예방의학회 2004 예방의학회지 Vol.37 No.2

Objectives : To investigate the utilization patterns of non-steroidal anti-inflammatory drugs (NSAIDs) among the elderly with osteoarthritis (OA) undergoing primary ambulatory care in Busan metropolitan city, Korea. Methods : OA patients, aged 65 years and over, were identified from the Korean National Health Insurance Review Agency drug prescription database. The subjects had at least one episode of claim for OA (ICD-10-CM: M15-M19) between August 1, 2000 and February 28, 2002. Trends in the determinations of NSAIDs utilization were identified using chi-squared tests for trend. Results : There were 47,711 osteoarthritic patients. The total number of visits by these patients was 177,443, with a total frequency for NSAID prescriptions of 214,952. Seventy-nine percent of the OA patients were female. NSAIDs were prescribed on 133,284 visits (75.1%) and the proportion of prescriptions was significantly increased with age. Only the proportion of visit when NSAIDs were prescribed decreased, from 65.1 to 43.5%, during the study period (p<0.001). However, the proportion of combined treatments with anti-ulcer drugs was increased. The use of NSAIDs injections was decreased. Of the individual NSAIDs, diclofenac (28.7% of total frequency of NSAID prescriptions), piroxicam (15.0%) and talniflumate (8.7%), were the most frequently prescribed. Among the NSAIDs prescribed OA visits, 45.7% used two or more NSAIDs. Conclusion : The total proportion of NSAIDs prescribed to the osteoarthritic patients was higher than in other studies. The decline in the use of NSAIDs during the study period, and the frequent selection of safer medications, such as combination therapy with anti-ulcer drug, may reflect the risk awareness of the use of NSAIDs.

Stomach Cancer Incidence, Mortality and Survival Rate in Korean Elderly Pharmacoepidemiologic Cohort (KEPEC) in1994∼1998

최남경,Kyung-Eun Youn,Dae-Seuk Heo,Seung-Mi Lee,Yooni Kim,박병주 대한암학회 2003 Cancer Research and Treatment Vol.35 No.5