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최낙경(NAK-KYUNG CHOI),강병윤(BYUNG-YOON KANG),조효제(HYO-JAE JO) 한국해양공학회 2002 韓國海洋工學會誌 Vol.16 No.6
In this paper, a study on the principal performance of the purse seiner ship in two vessel formations was conducted. For this task, the outline of the purse seiner fishing system in two vessel formations was reviewed. At the same time, based on the general arrangement plan, hull form of the main vessel was developed. And the stability and ship motion characteristics of the ship design were estimated. Finally, to verify the characteristics of the resistance and self-propulsion coefficient, a model test in a circulating water channel was performed. As a result, it is anticipated that this presentation will be used as the foundation material for research of purse seiner.
최낙경(NAK-KYUNG CHOI),강병윤(BYUNG-YOON KANG),조효제(HYO-JAE JO) 한국해양공학회 2002 韓國海洋工學會誌 Vol.16 No.6
The purpose of this study is to set up the optimum economical formation of the purse seiner fishing system. For this task, the characteristics of existing purse-seiner fishing system were reviewed, and the possible formations of the fleet in the purse-seiner fishing system were examined through the reallocation of function for each individual vessel. In addition, economic evaluations of the possible formations of the fleet are carried out. Consequently, it was found that 2-vessel formations have the most economic efficiency. Then, a conceptual system design for the main vessel in the 2-vessel formations was performed. As a result, this paper can be used as a helpful guideline to develop the most profitable and economical fishing system in the fleet type fishery.
좌측 정중 전두엽과 양측 기저절 경색 후 과잉성욕 증상과 강박 증상을 보인 환자 1례
김세주,김영신,최낙경,이병철,이만홍,Kim, Se Joo,Kim, Young Shin,Choi, Nak Kyung,Lee, Byung-Chul,Lee, Man Hong 대한생물정신의학회 2001 생물정신의학 Vol.8 No.2
60세 남자 환자로 좌측 정중 전두엽과 양측 기저절 경색 후 발생한 과잉성욕 증상과 강박 증상을 주소로 내원하였다. 환자는 뇌졸중 후에 발생한 운동 기능 장애는 시간이 경과하면서 호전되어 발병 1개월 이내에 거의 정상화된 반면 과잉성욕 증상과 강박 증상은 호전되지 않았다. 환자에게 과잉성욕 증상과 강박 증상을 목표로 fluvoxamine과 perphenazine을 처방하였으며 치료 시작 후 2개월이 경과하면서 환자의 과잉성욕 증상과 강박 증상은 서서히 사라졌다. 이 증례는 기저절-시상전두엽 회로가 성적 행동과 강박 증상의 조절에 있어 중요한 역할을 하고 있음을 시사한다고 할 수 있다. 과잉성욕 증상은 임상에서 간과하기 쉽고 또한 일반적으로 성적 활동에 대한 변화는 환자들 스스로 보고하지 않는 경향이 많다. 따라서 뇌졸중 환자, 특히 정중 전두엽이나 기저절 병변을 동반한 환자들의 경우에는 비록 그 병변이 측두엽 침범이 없거나 Kluver-Bucy syndrome의 전형적인 증상을 보이지 않는다 할 지라도 성욕등 성적 활동에 대한 체계적인 조사가 필요할 것으로 생각된다. 또한 과잉성욕 증상과 강박 증상을 함께 가지고 있는 경우 선택적인 세로토닌 재흡수 억제제의 사용이 두 증상 모두를 효과적으로 치료하는 데에 도움이 될 수 있을 것이다. Hyposexuality after stroke has been frequently observed, but hypersexuality as a sequela of stroke has not been commonly documented. We report a patient who exhibited hypersexuality and obsessive-compulsive behaviors after stroke in the region of the left mesial frontal cortex and both basal ganglia. At 2 months after stroke, he visited psychiatric unit due to these symptoms. His motor function was almost full recovered. He was treated with fluvoxamine and perphenazine. With two-month medication, his hypersexuality and obsessive-compulsive behavior disappeared. This case may indicate that basal ganglia-thalamocortical circuit plays an important role in the mediation of sexual behavior and obsessive-compulsive behavior. Since changes in sexual activity may not be spontaneously reported, a systemic inquiry into patient's sexual functioning after infarction in frontal lobe or basal ganglia is warranted.
정신분열병의 음성 증상에 대한 Loxapine과 Cyproheptadine의 병합 효과
김형섭(Hyeong-Seob Kim),고영민(Young-Min Ko),최낙경(Nak-Kyung Choi),김수동(Soo-Dong Kim) 대한생물치료정신의학회 2000 생물치료정신의학 Vol.6 No.2
Objectives : Atypical antipsychotics are known for the improvement effect for negative symptoms by the characteristics of high 5-HT₂/D₂ receptor occupancy ratio. We attempted this study to see if the improvement effect for negative symptoms by the combination of loxapine and cyproheptadine is similar to atypical antipsychotics. Methods : The Subjects were 15(male 9, female 6) who were chronic schizophrenics and in-patient. Their mean age was 38.33±5.51 years old, mean onset age 19.60±3.87 years old, mean duration of illness 221.33±57.04 months. Thier mean dose of medication, just before study, was 1367±7.80 ㎎/day as a haldol equivalent dose. We combined loxapine 10㎎/day and cyproheptadine 6 ㎎/day for the purpose of producing occupancy of 5-HT₂(more than 80%) and D₂(about 40%) receptors. The combination of medication was sustained for 6 weeks and after then typical antipsychotics(haloperidol) were administered for 4 weeks. The PANSS and ESRS were applied for the evaluations of clinical effects and side effects (just before trial of the combination, 3rd weeks and 6th weeks from the start of the combination). ANOVA was used to testify the statistical treatment. Results : As a result of the combination, the negative symptom, the general psychopathologic symptom, the PANSS total scores were improved significantly at the 6th weeks from the start of the combination(P<0.05). The improvement rate was 46.7% for the negative symptom, 33.3% for the general psychopathologic symptom, and 40.0% for the PANSS total score. However, there were no changes for positive symptoms. The total ESRS score was improved during the combination, however, those were aggravated followed as typical antipsychotics administration. Conclusion : The results of this study showed that the combination of loxapine(10㎎/day) and cyproheptadine(6㎎ /day) got the possibility for the treatment of the negative symptoms in schizophrenics and also those partially reconfirmed that the mechanism of the the atypical antipsychotics in the improvements of the negative symptoms is caused by high 5-HT₂/D₂ receptor occupancy ratio.
한국인에서 5-HT_(1Dβ) 유전자다형성과 성격 특성
김세주,김찬형,최낙경,홍현주,김성준,조대연,이홍식 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2
Objectives : Recently, there has been a growing enthusiasm in biological approach to personality ; the identification of genes responsible for particular personality traits. The aim of this study was to investigate the association between the 5-HT_(1Dβ) G861C polymorphism and personality traits. Methods : We recruited 218 normal subjects. The Korean version of the Temperament and Character Inventory (TCI) was used to assess personality traits. From blood samples taken from the subjects, DNA was isolated using standard techniques and the HT_(1Dβ) G861C polymorphism was genotyped by means of polymerase chain reaction and Homogeneous MassEXTEND method. We classified the subject into the GG, CG, and GG groups according to their genotypes. The differences in the temperament factors of the TCI between homozygote group (GG+CC genotype) and heterozygote group (CG genotype) weretested. Results : The heterozygote group had significantly lower Harm avoidance (HA) scores and higher Self-directedness scores(SD) than the homozygote group. Conclusion : In conclusion, we found some associations between the 5-HT_(1Dβ) G861C polymorphism and the personality dimension HA and SD in a normal population.