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Design of a High-Hole-Mobility Ge Transistor for Si-Driven Heterogeneous Integrated Circuits
조용범,유은선,조성재 한국과학기술원 반도체설계교육센터 2017 IDEC Journal of Integrated Circuits and Systems Vol.3 No.3
A high-hole-mobility transistor (HHMT) with an intrinsic Ge channel is optimally designed and its DC and high-frequency performances are investigated by technology computer-aided design (TCAD) simulation. An HHMT with a Ge channel and AlGaAs barrier on the Si substrate is characterized with a particular interest in the barrier design. More specifically, barrier doping concentration, total barrier thickness, and high-doped barrier thickness are considered as the critical design variables. A permissibly optimized device demonstrates cut-off frequency (fT) of 20 GHz and maximum oscillation frequency (fmax) of 80 GHz at a channel length of 90 nm. The Ge HHMT with an AlGaAs barrier has the potential to be a component in the heterogeneously integrated monolithic circuits made of Si, group-IV alloys, and III-V compound semiconductors where electronic and optical devices can be simultaneously integrated with enhanced device performances.
Lipopolysaccharide로 자극한 RAW264.7 대식세포에서 소리쟁이 뿌리 추출물 분획의 Nitric Oxide 생성억제효과
조용범,권남우,김재연,정소희,이문순 한국약용작물학회 2018 한국약용작물학술대회 발표집 Vol.2018 No.10
Background : In ancient, roots of Rumex crispus, called wooi-daehwang, were used for various symptoms and diseases like cough, phlegm, bronchitis and hepatitis, caused inflammatory. As a part of ongoing research to elucidate and characterize anti-inflammatory nutraceuticals, solvent-partitioned fractions from R. crispus root were tested for their ability to suppress inflammation. In this study, NO synthesis inhibitory activity of solvent-partitioned fractions from R. crispus root on LPS-stimulated RAW264.7 mouse macrophages was evaluated. Methods and Results : The EtOH extracts were suspended in water. The aqueous layer was further partitioned in diethylether, ethylacetate and n-butanol, sequentially. RAW264.7 cells were seeded onto 96-well plates, and cells were allowed to adhere for 6 h and then were pretreated with the R. crispus root extracts for 24 h. Cellular nitric oxide (NO) production was stimulated by adding lipopolysaccharide (LPS). Absorbance was measured at 520 ㎚ by microplate reader. NO synthesis inhibitory activity potential of these fractions was evaluated by assessing NO production by LPS-stimulated RAW264.7 cells in the presence and absence of the solvent-partitioned R. crispus root fractions. NO synthesis inhibitory activity of diethylether fraction diluted in 50 ㎍/㎖, 25 ㎍/㎖, 12.5 ㎍/㎖, 6.25 ㎍/㎖, 3.125 ㎍/㎖ was 79.2%, 70.9%, 59.5%, 16.1%, and 11.8%, respectively. And NO synthesis inhibitory activity range of another fractions, EtOAc, n-BuOH and aqueous layer, were 0 - 30.2%, 0 - 20.1% and 3.8 - 22.4%, respectively. Conclusion : From the above results, it showed that diethylether fraction have strong NO synthesis inhibitory activity, it was suggested that R. crispus root have NO synthesis inhibitory effects. R. crispus root possesses anthraquinones, such as chrysophanol, parietin, and anthrones etc. According to previous studies, R. crispus semen extract has analgesic and hepatoprotective effect as anti-inflammatory, and extract of R. napalensis has cyclooxygenase (COX)-2, COX-1 inhibitory and free radical scavenging effect. Our present study has shown that R. crispus root extracts anti-inflammatory effects probably by suppressing iNOS expressions, and resulting in the inhibition of NO synthesis.
조용범 한국외식경영학회 2004 외식경영연구 Vol.7 No.3
Five different Kimchi Snack dough with 2%, 4%, 6%, 8% and none of Freeze-Dried Kimchi Powder(FDKP) respectively were fried at the temperature of 170℃ for two minutes. Sensuous Evaluation showed that 4% FDKP snack revealed highest overall preference with nutty taste. The volatile substance of the chosen FDKP snack was analyzed with Automatic Thermal Desorber and total 26 ingredients were separated. They were thirteen kinds of aldehyde, three kinds of sulfide, one kind of ketone, acid, terpene respectively, and seven other ingredients. The highly correlated ingredients were analyzed with SIM and the correlation coefficient was 0.97, and which explains that the above mentioned ingredients work on the smell of FDKP snack.Conclusively, 4% FDKP did not show any significant difference from the controlled snack. Although 6% FDKP changed and increased the color, hotness, and Kimchi taste, 4% FDKP snack showed overall preference with nutty taste through GC/MS and sensuous Evaluation, which was chosen as the optimal.
The Effect of ZrO2 Slurry Application to the Pre-sintered Zirconia Surface on Bonding Strength
조용범,안종주,이소현,박태석,허중보 대한구강악안면임플란트학회 2020 대한구강악안면임프란트학회지 Vol.24 No.2
Purpose: This study was conducted to evaluate the roughness changes of zirconia surface after applying three different concentrations of ZrO2 slurry (ZirADD, PNUADD, Busan, Korea) to the pre-sintered zirconia surface and shear bond strength between zirconia and self-adhesive resin cement. Materials and Methods: Experimental groups were classified into control and three test groups according to the surface treatment with different slurry concentration (15% (ZA15), 30% (ZA30), and 50% (ZA50) group). After sintering all the specimen, roughness change was measured, and bond strength of the self-adhesive resin cement was examined. Results: Surface roughness values(Ra) significantly increased after applying ZrO2 slurry. ZA50 group showed the highest surface roughness value compared to others (p < .05). But the shear bond strength value (MPa) showed that ZA30 group was the highest value among the groups (p < .05). Conclusion: Within the limitations of this study, ZrO2 slurry application on pre-sintered zirconia surface can be an effective method to obtain strong bond between zirconia and self-adhesive resin cement by increasing zirconia surface roughness after zirconia sintering process.