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조동국,이균정,김수병,권선민,신태민,이경중,이용흠,Cho, Dong-Guk,Lee, Gyoun-Jung,Kim, Soo-Byung,Kwon, Sun-Min,Shin, Tae-Min,Lee, Kyoung-Joung,Lee, Yong-Heum 한국정보통신학회 2009 한국정보통신학회논문지 Vol.13 No.6
경락선상에서 침을 이용한 침술효과가 서양과학에 의해 현재까지 증명되지 않고 있다. 본 연구에서는 일반 수기침술에 의한 전기적 해석에 근거하여 수기자침을 사용하지 않고 전자기장 자극을 통한 경락전위변화를 측정함으로써 통증치료에 유의한 자극 시스템을 개발하였다. 특히 전자계를 발생시키고 집중시키기 위해서 전극 코어의 자성체에 코일을 감아 인가전류에 따른 자속밀도(강도)를 다양하게 발생시킬수 있도록 설계하였다. 자극모드도 다양하게 선택할수 있어서 다양한 치료효과를 기대할수 있도록 하였다. 유의성 평가를 위해 족양명위경상의 상거허혈과 하거허혈에 전극을 부착하고, 족삼리에 전자기자극을 하여 두 경혈점 사이에서 임피던스 변화에 따른 경락전위를 측정하였다. 그 결과, 수기자극에서 측정된 전위패턴과 유사한 전위를 관찰하였으며, 다양한 자극에 대한 반응특성도 확인하였다. 따라서, 비침습 전자기장 자극을 통한 인체의 유도전류를 유발시킬수 있음을 확인하였다. The effect of acupuncture that occurs at Meridians, can not be defined by western science. But we can find out the electrical effects when acupuncturing by measuring the charges meridians electric potential. So instead of using a needle to acupuncture, we used a electromagnet to give the same effect. We stimulated the meridians, with a electromagnet. Then we observed the pattern of the meridians potential, that occurred at ST-39 and ST-37. After doing clinical experiments with the acupuncture stimulation and the electromagnet stimulation. We found out the acupuncture stimulation and the electromagnet stimulations electric waves were similar. From this result, we knew it was possible to give similar effects to acupuncture stimulation by using electromagnets.
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이균정,조동국,김수병,권선민,신태민,이경중,이용흠,Lee, Gyoun-Jung,Cho, Dong-Guk,Kim, Soo-Byung,Kwon, Sun-Min,Shin, Tae-Min,Lee, Kyoung-Joung,Lee, Yong-Heum 한국정보통신학회 2009 한국정보통신학회논문지 Vol.13 No.7
통증을 치료하기 위한 방법으로 약물요법, 신경차단법, 외과적 수술 등이 있으며, 대체물리요법으로 침구치료, 초음파, 전기 치료, 자기장 치료 등이 응용되고 있다. 이중 전기치료 요법이 많이 이용되고 있으나, 피부나 피하조직의 임피던스에 큰 영향을 받으며, 주로 경피자극이 주된 방법으로 효과가 매우 확률론적이다. 본 연구에서는 집속형 자기장을 이용하여 경혈이나 치료점에 대한 국소 부위를 비침습적으로 자극 할 수 있는 새로운 시스템을 개발하였다. 수기자극과 유사한 자극을 유도할 수 있는 새로운 자기장 침 전극(자기장 자극의 효율성을 고려하여 새로운 형태)을 설계하였다. 개발된 시스템의 임상적 유효성 및 신뢰성을 평가하기 위하여 수기자극과 자기장 자극에 대한 경락전위변화를 측정하여 비교하였다. 실험 결과 자기장 자극 시 수기자극을 할 때 나타나는 충전 방전 형태의 전위변화와 유사한 경락전위변화가 측정되었으며, 자극방식, 세기, 빈도를 조절함에 따라 다양한 반응특성이 나타남을 확인하였다. 또한, 전자기장 자극에 의해 경락전위변화를 유도할 수 있어 이를 이용한 새로운 경혈자극 및 통증치료기로써의 가능성을 확인하였다. It is a method to treat pain using medication, neurotomy, and surgery. And acupuncture, ultrasound, electric treatment, and magnetic treatment are applied as a alternative physiotherapy. Electronic therapy is useful but it can be affected by impedance of skin or subcutaneous tissue. So, percutaneous stimulation is leading therapy, that is very randomly. We developed the system which can stimulate parts of acupuncture point noninvasively using the focused magnetic field. And we designed the magnetic stimulation electrode which is considered efficiency of the magnetic stimulation. It can make similar stimulation with manual acupuncture. To confirm the availability and reliability we compared Meridian Electronic Potential(MEP) change between manual acupuncture and magnetic stimulation. From this result, we found out the MEP changes of manual acupuncture and magnetic stimulation were similar. And there were various response properties as changes of stimulation method, intensity, and frequency. Also, the MEP change can be induced by electromagnetic stimulation. We confirmed that it is possible to use electromagnetic stimulation as a acupoint stimulation or pain treatment instrument.
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원지(遠志)가 만성적 뇌혈류저하 흰쥐의 β-Amyloid 축적과 기억장애에 미치는 영향
손영하 ( Young Ha Son ),김성재 ( Sung Jae Kim ),정민찬 ( Min Chan Chung ),조동국 ( Dong Guk Cho ),조우성 ( Woo Sung Cho ),신정원 ( Jung Won Shin ),박동일 ( Dong Il Park ),손낙원 ( Nak Won Sohn ) 대한본초학회 2014 大韓本草學會誌 Vol.29 No.6
Objectives : This study was investigated the effects of the root of Polygala tenuifolia (POL) on learning and memory impairment induced by chronic cerebral hypoperfusion in rats. Methods : Chronic cerebral hypoperfusion was produced by permanent bilateral common carotid artery occlusion (pBCAO). POL was administered orally once a day (130 mg/kg of water-extract) for 28 days starting at 4 weeks after the pBCAO. The acquisition of learning and the retention of memory were tested on 9th week after the pBCAO using the Morris water maze. In addition, effects of POL on Aβ generation and expressions of APP and BACE1 were observed in the hippocampus of rats. Results : POL significantly prolonged the swimming time spent in target quadrant and significantly reduced the swimming time spent in the quadrant far from the target. POL significantly increased the percentage of swim in the targer quadrant in the retention test, while POL was not effective on the escape latencies in the acquisition training trials. POL significantly reduced the levels of Aβ(1-40) and Aβ(1-42) in the cerebral cortex and the level of Aβ(1-42) in the hippocampus produced by chronic cerebral hypoperfusion. POL also significantly attenuated the up-regulation of APP and BACE1 expression in the hippocampus produced by chronic cerebral hypoperfusion. Conclusions : The results show that POL alleviated memory deficit and up-regulation of Aβ and BACE1 expressions in the hippocampus. This result suggests that POL may exert ameliorating effect on memory deficit through inhibition of β-secretase activity and Aβ generation.
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이재철(Jae-Chul Lee),안성훈(Sung-Hoon Ahn),조동국(Dong-Guk Cho),이선영(Caroline Sunyong Lee) (사)한국CDE학회 2010 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2010 No.1
The final goal of this research is the precise fabrication of functionally graded material (FGM) based on nickel and alumina using pressureless sintering method. Deformation of specimen during the manufacturing process has to be predicted and controlled for the goal. In this paper, a interpolation model based on experimental shrinkage data of 4 layers from the 11 layered FGM was proposed to predict the shrinkage of the other layers. Temperature dependent elastic modulus was investigated by literatures, and elastic modulus of nickel on 1350℃ was selected with 3 cases to verify a phenomenon of liquid fraction increase in only 100% nickel. Deformed shape after sintering was predicted by proposed interpolation model, selected properties, and finite element method. The predicted results were compared with measurement data of fabricated FGM for verification of the phenomenon. And it was verified that liquid fraction of only 100% nickel on 1350℃ was increased through the numerical result.
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