자궁외임신에서 내 외과적 치료의 비용 절감 효과 비교

정대영(Dae Young Chung),신종철(Jong Chul Shin),백은정(Eun Jung Baik),이영(Young Lee),유영옥(Young Oak Lew),이종건(Jong Kun Lee),김창이(Chang Yi Kim),김대훈(Dae Hoon Kim),김수평(Su Pyung Kim) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.12

N/A The incidence of ectpic pregnancy has increased rapidly over the past decade. Currently, the complications of this disorder make it one of the leading causes of maternal mortality and morbidity. In the late 1980s, reports of successful use of methotrexate (MTX) as a non surgical treatment for ectopic pregnancy (EP) also began to appear in the literature. With MTX emerging as a possible alternative management of selected women with an EP, an analysis of its comparative costs is now needed. We examined retrospectively the costs associated with management of EP in our hospital. We selected 30 women with EPand divided them into two groups of MTX treated group (n= l0) and surgically treated group (n=20). There were no statistically significant differences in the doctors fee, room, charge and cost of laboratory and radiologic examination between two groups. But We found significant reduction in cost with regard to pharmacy, injection, procedure and operation of MTX treated group compared to surgically treated group (p<0.05). Consequently the use of MTX for EP should still be considered investigational; we recognize and agree that the evolution of this remedial option should be based primarily on its ability to decrease morbidity and mortality rather than on its ability to reduce costs. If medical treatment proves to be effective, the potential cost savings demonstrated in this report will become an important influential factor on selecting alternative remedy.

Biosorption of Metal Ions by Seaweed Alginate, Polyguluronate, and Polymannuronate

Dae-Young Jung(정대영),Chang-Woo Son(손창우),Sung-Koo Kim(김성구),Yi-Joon Kim(김이준),Chung-Han Chung(정정한),Jin-Woo Lee(이진우) 한국생명과학회 2009 생명과학회지 Vol.19 No.5

P1/2 값을 참고로 비교한 알긴산, 폴리글루론산 및 폴리만뉴론산의 금속이온들에 대한 상대적인 친화성은 다음과 같다; 1) 알긴산: Cu<SUP>2+</SUP>>Cd<SUP>2+</SUP>>Pb<SUP>2+</SUP>>Fe<SUP>3+</SUP>>>Zn<SUP>2+</SUP>>Sr<SUP>2+</SUP>>Ca<SUP>2+</SUP>>Co<SUP>2+</SUP>>>Cr<SUP>6+</SUP>>Mn<SUP>2+</SUP>>>Hg<SUP>2+</SUP>, Mg<SUP>2+</SUP>, Rb?, 2) 폴리글루론산: Cd<SUP>2+</SUP>>Cu<SUP>2+</SUP>>Pb<SUP>2+</SUP>>Fe<SUP>3+</SUP>>>Ca<SUP>2+</SUP>>Sr<SUP>2+</SUP>, Zn<SUP>2+</SUP>, Co<SUP>2+</SUP>>>Mn<SUP>2+</SUP>>Cr<SUP>6+</SUP>>>Hg<SUP>2+</SUP>, Mg<SUP>2+</SUP>, Rb?, 그리고 3) 폴리만뉴론산: Cd<SUP>2+</SUP>, Cu<SUP>2+</SUP>>Fe<SUP>3+</SUP>>Pb<SUP>2+</SUP>>Ca<SUP>2+</SUP>>Zn<SUP>2+</SUP>>Sr<SUP>2+</SUP>>Co<SUP>2+</SUP>>Cr<SUP>6+</SUP>>>Mn<SUP>2+</SUP>>>Hg<SUP>2+</SUP>, Mg<SUP>2+</SUP>, Rb?. 알기산 1 g에 흡착하는 Cd<SUP>2+</SUP>, Cu<SUP>2+</SUP>, Fe<SUP>3+</SUP>, Pb<SUP>2+</SUP> 및 Zn<SUP>2+</SUP>의 양은 363.5±45.0, 226.3±9.2, 1,299.4±81.3, 500.7±27.7 및 165.9±11.4 ㎎이었으며, 폴리글루론산 1g에 흡착하는 Cd<SUP>2+</SUP>, Cu<SUP>2+</SUP>, Fe<SUP>3+</SUP>, Pb<SUP>2+</SUP> 및 Zn<SUP>2+</SUP>의 양은 354.5±26.5, 177.6±8.7, 1,288.6±60.1, 424.0±7.4 및 140.2±28.5 ㎎이었으나, 폴리만뉴론산 1 g에 흡착하는 Cd<SUP>2+</SUP>, Cu<SUP>2+</SUP>, Fe<SUP>3+</SUP>, Pb<SUP>2+</SUP> 및 Zn<SUP>2+</SUP>의 양은 329.0±10.3, 226.9±1.9, 1,635.6±11.1, 419.8±12.6 및 251.0±49.1 ㎎이었다. 폴리만뉴론산은 알긴산보다 높은 용해도와 폴리글루론산보다 높은 금속이온에 대한 친화성 때문에 독성이 높은 중금속이나 경제성이 높은 금속을 선택적으로 분리하는 데 사용할 수 있을 것이다. Based on P1/2 values, relative affinities of alginate, polyguluronate, and polymannuronate for metal ions are, in order, as follows; 1) seaweed alginate: Cu<SUP>2+</SUP> > Cd<SUP>2+</SUP> > Pb<SUP>2+</SUP> > Fe<SUP>3+</SUP> >> Zn<SUP>2+</SUP> > Sr<SUP>2+</SUP> > Ca<SUP>2+</SUP> > Co<SUP>2+</SUP> >> Cr<SUP>6+</SUP> > Mn<SUP>2+</SUP> >> Hg<SUP>2+</SUP>, Mg<SUP>2+</SUP>, Rb?, 2) polyguluronate: Cd<SUP>2+</SUP> > Cu<SUP>2+</SUP> > Pb<SUP>2+</SUP> > Fe<SUP>3+</SUP> >> Ca<SUP>2+</SUP> > Sr<SUP>2+</SUP>, Zn<SUP>2+</SUP>, Co<SUP>2+</SUP> >> Mn<SUP>2+</SUP> > Cr<SUP>6+</SUP> >> Hg<SUP>2+</SUP>, Mg<SUP>2+</SUP>, Rb? , and 3) polymannuronate: Cd<SUP>2+</SUP>, Cu<SUP>2+</SUP> > Fe<SUP>3+</SUP> > Pb<SUP>2+</SUP> > Ca<SUP>2+</SUP> > Zn<SUP>2+</SUP> > Sr<SUP>2+</SUP> > Co<SUP>2+</SUP> > Cr<SUP>6+</SUP> >> Mn<SUP>2+</SUP> >> Hg<SUP>2+</SUP>, Mg<SUP>2+</SUP>, Rb?. Amounts of the metal ions, Cd<SUP>2+</SUP>, Cu<SUP>2+</SUP>, Fe<SUP>3+</SUP>, Pb<SUP>2+</SUP>, and Zn<SUP>2+</SUP>, bound to 1 g of seaweed alginate, were measured as 363.5±45.0, 226.3±9.2, 1,299.4±81.3, 500.7±27.7, and 165.9±11.4 ㎎, respectively. Amounts of the metal ions, Cd2+, Cu2+, Fe3+, Pb2+, and Zn2+, bound to 1g of polyguluronate, were 354.5±26.5, 177.6±8.7, 1,288.6±60.1, 424.0±7.4, and 140.2±28.5 ㎎, respectively, whereas those bound to 1 g of polymannuronate were 329.0±10.3, 206.9±1.9, 1,635.6±11.1, 419.8±12.6, and 251.0±49.1 ㎎, respectively. Due to its higher solubility than alginate and higher affinity for metal ions than polyguluronate, polymannuronate can be used for bioremediation or biosorption of toxic and/or noble metal ions.

다수의 경쟁이 존재하는 환경에서 적시 스케줄링에 관한 연구

정대영(Dae-Young Chung) 한국경영과학회 2012 韓國經營科學會誌 Vol.37 No.1

We consider a multi-agent scheduling problem such that each agent tries to maximize the weighted number of just-in-time jobs. Two objectives are considered : the first is to find the optimal solution for one agent with constraints on the other agents’ weight functions, and the second is to find the largest set of efficient schedules of which corresponding objective vectors are different for the case with identical weights. We show that when the number of agents is fixed, the single machine case with the first objective is NP-hard in the ordinary sense, and present the polynomial-time algorithm for the two-machine flow shop case with the second objective and identical weights.

광주와 전남지역 사육견의 개심장사상충(Dirofilaria immitis)감염률 조사

정대영 ( Dae Young Chung ),김희정 ( Hee Jeong Kim ),이태욱 ( Tae Uk Lee ),김내영 ( Nae Young Kim ),이정치 ( Jeong Chee Lee ),신성식 ( Sung Shik Shin ) 한국가축위생학회 1997 韓國家畜衛生學會誌 Vol.20 No.1

We have investigated the prevalence of canine heartworm (Dirofilaria immitis) infection among 100 mixed-breed dogs raised in Chonnam Province(Koheung, Posung, Changheung, and Hwasoon) and 100 dogs randomly selected from visiting dogs to the College of Veterinary Medicine, Chonnam National University for routine physical examination. Blood samples taken from dogs were examined for the presence of Dirofilaria immitis microfilaria by the modified Knott`s test, and an antigen test which was based on the sandwich ELISA(DiroCHEK®, Synbiotics, Inc., San Diego, California, USA) was used to detect the adult heartworm-specific antigen from serum samples. The results were then compared with those of the modified Knott`s test. Five(2.5%) of the 200 examined dogs were microfilaria-positive, while 8 dogs(4%) were anti-gen-positive, which suggested that the antigen test was more sensitive than the microfilarial test in detecting heartworm infection. All dogs that were microfilaria-positive were also antigen-positive. The place of origin of the heartworm-positive dogs were of Naju (4/26, 15.4%), Koheung(3/32, 9.4%), and Hwasoon (1/19, 5.3%), while none of dogs raised in Kwangju, Posung, and Changheung areas were infected with the parasite. Although not significant, more infected dogs were observed in older ages, while the difference in infection rate between male (4/98, 4.1%) and female (4/102, 3.9%) was not recognized. Our results indicated that a relatively low infection rate was observed in dogs raised in Kwangju and Chonnam area compared to the infection rate reported previously in other areas of South Korea.

개인용 컴퓨터를 이용한 임신 주수 계산 프로그램

정대영 ( Dae Young Chung ),신종철 ( Jong Chul Shin ),김사진 ( Sa Jin Kim ),이종승 ( Jong Seung Lee ),이영 ( Young Lee ),이귀세라 ( Gui Se Ra Lee ),이종건 ( Jong Kun Lee ),김수평 ( Soo Pyung Kim ) 대한주산의학회 1999 大韓周産醫學會雜誌 Vol.10 No.2

위점막에서 C형 간염바이러스의 항원 단백의 발견

정대영 ( Dae Young Cheung ),김재광 ( Jae Kwang Kim ),김진일 ( Jin Il Kim ),한준열 ( Joon Yeol Han ),정규원 ( Kyo Won Chung ),선희식 ( Hee Sik Sun ) 대한소화기학회 2005 대한소화기학회지 Vol.45 No.4

Background/Aims: As a preliminary study to test the possibility of oral transmission of hepatitis C virus (HCV), many investigations in order to detect the extrahepatic localization of HCV have been performed. In this study, we examined the presence of HC

총담관 담석에 의한 급성 췌장염과 담관염에 동반된 간문맥 혈전증 1예

정대영 ( Dae Young Cheung ),김재광 ( Jae Kwang Kim ),조돈현 ( Don Hyoun Jo ),오현종 ( Hyun Jong Oh ),김태호 ( Tae Ho Kim ),이소연 ( So Yeon Lee ),박수헌 ( Soo Heon Park ),한준열 ( Joon Yeol Han ),정규원 ( Kyu Won Chung ),선희식 ( 대한소화기학회 2005 대한소화기학회지 Vol.46 No.1

제왕절개술 후 통증관리 방법 선택이 제통 효과와 수술 후 경과에 미치는 영향

이영(Young Lee),김사진(Sa Jin Kim),권인(In Kwun),정대영(Dae Young Chung),김창이(Chang Yi Kim),김수평(Soo Pyung Kim),송지민(Ji Min Song),류진희(Jin Hee Yoo),이지영(Ji Young Lee),한상아,김진철(Jin Chul Kim),김창재(Chang Je Kim) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.11

목적 : 본 연구는 통증 관리 방법 선택에 따른 제통 효과의 차이와 수술후 회복기에 미치는 영향을 연구하고자 하였다. 연구 방법 : 총 90명의 제왕절개술을 시술 받은 산모들을 무작위로 군 당 30 명씩 배정하여 이중 맹검 법으로 연구하였다. 수술후 통증은 고식적인 아편양제재의 근 주법(IM군)과 통증자가조절장치를 이용하여(D군, DV군) 조절하였고 수술후 산모가 깨어나 통증을 호소할 때부터 수술후 48시간까지 시행하였다. DV군에선 diclofenac 을 통증관리 보조제로 이용하여 75 mg을 첫 근주후 매 12 시간마다 근 주 하였다. 사용된 아편양 제재의 총량, 통증 점수, 부작용 및 술후 첫 보행시기를 비교하여 각 통증 관리 방법의 유용성 과 안전성을 비교하였다. 결과 : 총 아편양제재의 사용량이 DV군에서 다른 두 군에 비해 40-50% 감소되었다. 통증 점수는 DV군에서 6, 12 및 24시간에 다른 두군에 비해 의의 있게 낮았다(p <0.05).오심, 구토 및 어지럼증의 발생은 IM 군에서 통증자가조절장치를 이용한 두 군 보다 의의 있게 높았다(p<0.05). diclofenac을 통증 관리 보조제로 사용한 군 과 사용하지 않은 군간에 혈색소치, 헤마토크리트, 혈소판수 및 출혈시간 등 검사 결과에 차이가 없었다. 수술후 첫 보행은 DV군에서 다른 두 군에 비해 의의있게 일찍 개시되었다(p <0.05). 결론 : 제왕절개술후 통증 관리에 아편양제재를 통증자가조절장치로 투여하며 diclofenac을 보조 제로 이용한 방법이 가장 효과적이고 안전한 방법이었다. 그러나 diclofenac의 출혈 경향 유무에 대한 더 자세한 연구가 필요하리라 여겨진다 Objective: We investigated influence of choice of pain control method on analgesic effect and postoperative course after cesarean section. Methods: Ninety parturients were randomly allocated to three groups and each group had 30 women. The postoperative pain was controlled with classical intramuscular injection in IM group and PCA (patient-controlled analgesia)device in meperidine (D) and meperidine+diclofenac (DV) group for up to 48 hours after Cesarean section when the parturients awoke and complained pain. The parturients received intramuscular diclofenac 75 mg every 12 hours in DV group. We evaluated usefulness and safety of each pain control method on postoperative opioid requirement, numerical rating score of pain, side effect and first ambulation time for 48 hours after operation. Results: Total opioid requirement was decreased almost 40-50% in DV group. Pain score lowered significantly at 6, 12 and 24 hours in DV group(p <0.05). Nausea,Vomiting and Dizziness were increased in IM group than PCA group(p <0.05). There was no difference in laboratory data including hemoglobin, hematocrit, platelet count and bleeding time in diclofenac used group. Ambulation was started earlier significalty in DV group after Cesarean section(p <0.05). Conclusion: We concluded that diclofenac combined PCA is the most effective and safe method in pain control after cesarean section. But it is necessary to try further evaluation of hemostatic effect of diclofenac.

성별에 따른 태아 심장 박동 분석

이영(Young Lee),백은정(Eun Jeong Baik),신종철(Jong Chul Shin),정대영(Dae Young Chung),김수평(Soo Pyung Kim),김창이(Chang Yee Kim),문희봉(Hee Bong Moon),이종승(Chong Seung Yi) 대한산부인과학회 2000 Obstetrics & Gynecology Science Vol.43 No.1

목적: 태아 심박동(fetal heart rate; FHR)은 자율신경계의 조절로 나타나는 현상으로 정상 심박동은 자체의 주기성, 교감 신경 또는 미주 신경 및 부교감 신경으로부터 영향을 받는다. 자율신경 하에 조절되는 심장박동은 성인의 경우 나이 성별에 따른 차이가 있으며, 성별에 따른 자율신경의 생리 작용이 다르다는 것을 알 수 있다. 이에 저자들은 태아 성별에 따른 임상적 여러 변수들 그리고 태아 심박동과 차이를 연구하였다. 연구 방법: 가톨릭 의과대학 산부인과학 교실에 산전 진찰 및 분만을 위해 내원한 산모 중 전자식 태아감시 장치를 시행하였고, 본원에서 분만하여 신생아 임상 소견을 알 수 있었던 317명의 667개의 태아 심박동 자료를 대상으로 하여, 기초 태아 심박동수, 태아 심박동 증가, 태아 심박동 감소, Percent acceleration time(PAT) 및 Percent deceleration time(PDT)를 계산하였고, 변이도로 표준 편차, Mean minute range(MMR)의 장기변이도(LTV) 및 단기변이도(STV)를 계산하였다. 결과: 분석 결과 남아 분만군과 여아분만군의 비교에서 기초 태아 심박동수 137.64±13.68 bpm, 140.51±12.43bpm(P=0.007), PAT는 6.10±4.00bpm, 4.90±3.34bpm(P=0.001), 그리고 PDT는 7.50±8.70bpm, 6.18±7.70bpm(P=0.039)으로 유의한 차이가 있었으나, 표준 편차는 8.84±10.11bpm, 8.11±3.56bpm, LTV는 80.38±62.79msec과73.65±54.60msec, STV는 14.06±9.79msec과 13.33±12.32msec로 차이가 없었다. 결론: 위의 결과로 남아와 여아의 태아 심박동은 차이가 있으며, 이는 발생 시기부터의 부교감 신경과 교감 신경의 발달 차이로 인한 심장 및 체강의 연결계의 차이가 임신 기간 중에 발생한는 것이 원인으로 사료 된다. Objectives: The purpose of this study is to analyze the previously unreported effect of fetal sex on the fetal heart rate and to measure its magnitude in relation to the effects of other independent clinical variables. Methods: Three hundred and seventeen pregnant women who were able to provide electronic fetal heart rate monitoring were evaluated. On the basis of fetal sex after birth, 167 pregnant women who delivered male neonate were for males group and 146 examples who delivered female neonate were for female group. We analyzed fetal heart rate data using the Catholic Computer Assisted Obstetric Diagnosis System(CCAOD). Results: Female fetuses had significantly faster basal heart rate(140.51±12.43bpm) than male fetuses(137.64±13.68 bpm).(P=0.007) Percent acceleration time(PAT) increased significantly for males(6.10±4.00bpm), comparing to females(4.90±3.34bpm).(P=0.001) Also percent deceleration time(PDT) was significantly higher in male fetuses(7.50±8.70bpm) than female fetuses(6.18±7.70bpm).(P=0.039) But there was no differences in standard deviation(SD)(8.84±10.11bpm, 8.11±3.56bpm), long term variation(LTV)(80.38±62.79msec, 73.65±54.60msec), and short term variation(STV)(14.06±9.79msec, 13.33±12.32msec) between male and female fetuses. Conclusion: The fetal heart rate of female fetuses differ from that of male fetuses. Computerized linear analysis and nonlinear analysis of antepartum fetal heart rate will need to take into account the multiple factors that influence the fetal heart rate to identify precisely which pattern predict clinical outcome.

특집 1 : 동북아시아 청동기문화의 지역성 ; 한국고대학술회의 2004년 춘계학술회의 토론 요지 : 토론 ; 동북아시아 청동기문화의 지역성

최정필 ( Chung Pil Choi ),강인욱 ( In Uk Kang ),안신원 ( Shin Won Ahn ),정대영 ( Dae Young Dae ) 한국고대학회 2004 先史와 古代 Vol.20 No.-