http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
실란처리된 하이드록시프로필 메틸셀룰로오스/상전이된 칼슘포스페이트 복합체 골시멘트의 제조 및 특성평가
정나현,김동현,조훈상,윤석영,Jeong, Nahyun,Kim, Dong-Hyun,Cho, Hoon-Sang,Yoon, Seog-Young 한국결정성장학회 2016 한국결정성장학회지 Vol.26 No.6
Silanized-hydroxypropyl methylcellulose (Si-HPMC)/phase transformed calcium phosphate (PTCP) composites are prepared to purpose application of injectable bone cements with enhanced biocompatibility. The crystal structure and chemical state of the synthesized PTCP and Si-HPMC as solid and liquid phase of the composite cements were measured by XRD and FT-IR. The handling and mechanical properties of cements were measured by injectability tests and three-point bending tests. The in-vitro mechanical properties, XRD, and SEM results of bone cements were showed that enhanced hardening behavior was an inherent function of bone cements after in-vitro test. The cytotoxicity result of bone cements also was showed enhanced biocompatibility. Therefore, these injectable cements had potential be used as calcium phosphate cements for biomedical applications. 실란처리된 하이드록시프로필 메틸셀룰로오스/상전이된 칼슘포스페이트 복합체 시멘트는 향상된 생체적합성을 가지는 주입이 가능한 골시멘트로서 제조 되었다. 복합체 시멘트의 고체상과 액체상으로서 상전이된 칼슘포스페이트와 실란처리된 하이드록시프로필 메틸셀룰로오스의 결정구조 및 화학적 상태는 XRD 및 FT-IR에 의해 측정 되었고, 시멘트의 조작성 및 기계적 물성은 주입성 및 3점 굽힘 시험에 의해 측정하였다. 체외에서 진행된 골시멘트의 기계적 물성, XRD 및 SEM 결과는 골시멘트의 고유 기능으로서의 향상된 경화거동을 보였다. 또한 골시멘트의 세포독성 결과 향상된 생체적합성을 보였다. 따라서 이러한 주입이 가능한 시멘트는 생체의학 응용에 대한 칼슘포스페이트 시멘트로서 사용이 가능하리라 판단되어진다.
정나현(Na-Hyeon Jung),김지영(Ji-Young Kim),박지희(Ji-Hee Park),양일영(Il-Young, Yang) 한국신뢰성학회 2020 한국신뢰성학회 학술대회논문집 Vol.2020 No.7
Purpose : In a general case, the life test could designed based on the failure mode and mechanism of components and materials or field failure cases. However, it is difficult to predict which components or parts could cause failure of an assembly in case of a new developed product or assembly that combined many different components and materials. Therefore, in this paper we studied the life test for the new developed assembly A that combined many electronic components. Methods : It is important for the life test design to choose an effective stress of the assembly A. The effective stress factor selecting is most important especially when we could not know the failure mode and mechanism. In this paper, the effects of every possible stresses were analysed using QFD(Quality Function Deployment) method. Temperature difference between ground and high altitude was found as the effective stress of the assembly A. To accelerate temperature difference we designed the life test that accelerated the life cycle. Result : The life test was designed for the new developed assembly A and the failure were found in every samples at the similar test step. Samples were three. The fault was not occurred the specific component but the connect part that connect between two circuit cards. We predicted the MCBF(Mean Cycle Between Failure) of the assembly A using every samples’ failure cycles based on a statistical analysis. Conclusion : In this paper the life test design was analysed and done for the assembly A which combined many electronic components. It is difficult to generalized the life test method for new developed assemblies. Therefore, from the beginning of various life test analyses are necessary to distinguish factors that affect the lifetime.
Effects of pregnancy serum and scriptaid on development in early partheno embryo
오민기,정나현,김대승,윤종택 사단법인 한국동물생명공학회 2020 한국동물생명공학회지 Vol.35 No.2
Partheno Embryo's research is known to play a very important role in identifying the development of embryonic cells or analyzing the genetic mechanisms of embryonic development, but the information on apoptosis formed during the early stage of development on Partheno Embryo is very little. Therefore, this study analyzed whether the embryonic cell death of unit embryos can be inhibited by adding Scriptaid, one of HDACi, which plays a role in demethylation of histone proteins as a method of regulating the cell cycle in the early embryo development of Partheno Embryo. As a result, the differentiation rate was higher in the group that added Scriptaid and FBS, but the cellular development was higher in the group that added pregnant serum to Scriptaid. As a result of analyzing the expression of the gene through IF and PCR, the group with the addition of gestational serum increased the expression of BCL2 and PCNA, which affects the anti-Casp3 action in cell survival. In addition, it is interpreted that treatment of Scriptaid for 16 hours, rather than 24 h treatment lowers the expression of Casp-3, a representative factor of apoptosis, and also increases embryonic development, thus affecting early embryo development. Therefore, it is concluded that the 16-hour treatment of Scriptaid and the use of gestational serum will inhibit cell death in the early embryonic development and increase the development rate of the embryo.