간호대학생의 임상실습만족도와 간호전문직관에 영향을 미치는 요인

정기태,하유정,오난영,김소연,권민지,이나현,이유리,양경희 한국간호연구학회 2018 한국간호연구학회지 Vol.2 No.1

Purpose : The purpose of this study is to investigate the level of satisfaction with clinical practice and nursing professional value, and influencing factors in nursing students during experiencing clinical practice. Methods : The data were collected for descriptive study from 200 students in I city from June 5 to 12, 2017. For data analysis, t-test, ANOVA, Scheffè test, Pearson correlation coefficients, and Multiple regression were performed using SPSS WIN 19.0. Results : Satisfaction with clinical practice was scored 3.59 points and nursing professional values was scored 3.82 points out of 5 on average. Satisfaction with clinical practice was higher under the age of 29(t 2.78, = p .014), male students(t 2.70, == p .008), and third grade(t 3.53, == p .001). Satisfaction = for clinical practice was positively related to personal relationship(r .26, = p .001), period of clinical practice =< (r .17, = p .019), and professional values(r .576, == p .000). Nursing professional values was positively relate to = personal relationship(r .34, = p .001), and colleague relationship(r .20, <= p .004). The fac = tors affecting satisfaction with clinical practice were grade(β .236), gender( =β.162), personal relationship( =β =.172), & religion (β .145) and explained 13.8% of it. Satisfaction with clinical practice( =β .527) and personal relationship( =β .209) explained 36.7% of nursing professional values.= Conclusion : Based on the results of this study, to enhance nursing Professional values, it is necessary to improve the nursing student’s satisfaction for clinical practice and to explore the affecting factors on them.

The Effect of Urinary Trypsin Inhibitor Against Neuropathic Pain in Rat Models

정기태,이현영,윤명하,임경준 대한통증학회 2013 The Korean Journal of Pain Vol.26 No.4

Background: Nerve injury sometimes leads to chronic neuropathic pain associated with neuroinflammation in the nervous system. In the case of chronic neuropathic pain, the inflammatory and algesic mediators become predominant and result in pain hypersensitivity following nervous system damage. It is well known that urinary trypsin inhibitor (ulinastatin, UTI) has an anti-inflammatory activity. Recently, the neuroprotective action of UTI on the nervous system after ischemic injury has been reported. Thus, we evaluated the neuroprotective effect of ulinastatin in a rat model of neuropathic pain.Methods: Neuropathic pain was induced with L5 spinal nerve ligation (SNL) in male Sprague-Dawley rats weighing 100−120 g. The rats were divided into 3 groups, with n = 8 in each group. The rats in the control group (group 1) were administered normal saline and those in group 2 were administered UTI (50,000 U/kg) intravenously through the tail vein for 3 days from the day of SNL. Rats in group 3 were administered UTI (50,000 U/kg) intravenously from the 5th day after SNL. The paw withdrawal threshold was measured using the von Frey test for 3 days starting from the 5th day after SNL. Results: The paw withdrawal thresholds were significantly increased in the rats of group 2 compared to the other groups (P < 0.05). Conclusions: Ulinastatin, which was administered for 3 days after SNL, increased the paw withdrawal threshold and it could have a neuroprotective effect in the rat model of neuropathic pain.

오미자종자의 항산화성, 항균성, 아질산염소거능

정기태,주인옥,최정식,홍재식,Jung, Gi-Tai,Ju, In-Ok,Choi, Joung-Sik,Hong, Jae-Sik 한국식품과학회 2000 한국식품과학회지 Vol.32 No.4

오미자 종자의 몇가지 용매 추출물과 분획물의 항산화성, 항균성, 아질산염 소거능에 대하여 확인한 결과 다음과 같다. 돈지와 linoleic acid에 대한 항산화력은 오미자종자의 methanol 추출물이, 대두유는 ethanol 추출물이 가장 효과적이었으며 free radical 소거 활성은 methanol추출물의 ethyl acetate 분획에서 DPPH free radical 소거 활성이 가장 컸다. 오미자 종자 추출 용매별 항균 효과는 L. planterum, B. subtilis, E. coli, P. citrinium는 methanol 추출물이, S. aureus와 S. typhimurium은 ethyl acetate 추출물의 항균 활성이 가장 컸다. 전반적으로 항균 활성이 큰 methanol 추출물을 분획하여 항균력을 검토한 바, buthanol 분획물이 L. planterum, B. subtilis, S. aureus, S. typhimurium 및 E. coli에서 항균 활성이 가장 강하였다. 아질산염 소거 효과는 반응 pH가 낮을수록 우수했으며 methanol 추출물의 buthanol 분획이 다른 추출물과 분획물 중에서 가장 높은 아질산염 분해능을 나타내었다. This study was carried out to examine the antioxidative, antimicrobial and nitrite scavenging effects of various solvent extracts and different solvent fractions from Schizandra chinensis RUPRECHT(Omija) seed. The results were as follows; The antioxidative activities using lard, soybean oil and linoleic acid were the highest in methanol, ethanol and methanol extract from omija seed, respectively. The free radical scavenging activity using DPPH method was the strongest in acetate fraction of methanol extract from seed. The methanol extract from omija seed had the strongest antimicrobial activities to L. plantarum, B. subtilis, E. coli and P. citrinum, while ethyl acetate extract had the strongest against S. aureus and S. typhimurium. The buthanol fraction from methanol extract had the highest antimicrobial activities, followed by B. subtilis, L. plantarum, E. coli, S. aureus and S. typhimurium. The nitrite scavenging ability was pH dependent, highest at pH 1.2 and lowest at pH 6.0. The buthanol fraction of methanol extract from omija seed had more effective nitrite scavenging ability than other fractions of extracts.

FTTH Killer Application

정기태 한국통신학회 2004 한국통신학회 워크샵 Vol.2004 No.10

Effects of Palonosetron, a 5-HT3 Receptor Antagonist, on Mechanical Allodynia in a Rat Model of Postoperative Pain

정기태,윤명하,이현영,유보연,김동규,임경준 대한통증학회 2013 The Korean Journal of Pain Vol.26 No.2

Background:5-hydroxytryptamine 3 (5-HT3) receptors have been known to be associated with the modulation of nociceptive transmission. However, it is uncertain whether 5-HT3 plays a role in the antinociceptive or pronociceptive pathway for incisional pain. In this study, we evaluated the effects of palonosetron, a 5-HT3 receptor antagonist, on incisional pain in rats when administered intrathecally or intraplantarly. Methods:An intrathecal catheter was implanted through the cisterna magna and placed in the intrathecal space of rats. An incision in the plantaris muscle of the right hind paw was done under anesthesia with sevoflurane. Withdrawal thresholds were evaluated with the von Frey filament after 2 hours. Palonosetron (0.5 and 0.1 mg intrathecally; 0.5 mg intraplantarly) was administered and the thresholds were observed for 4 hours. Results:Mechanical hypersensitivity developed after the incision. Intrathecal palonosetron (0.5 mg and 0.1 mg) did not alter the paw withdrawal threshold. Intraplantar palonosetron (0.5 mg) also did not change the paw withdrawal threshold. Conclusions:Intrathecal and intraplantar palonosetron (0.5 mg) had no effect on modulating the mechanical hypersensitivity in the incisional pain model of rats.

Combination of nefopam and remifentanil is more effective to reduce rocuronium-induced withdrawal response compared with remifentanil alone: a prospective, double-blinded, randomized control study

정기태,김상훈,소금영,문현매 대한마취통증의학회 2018 Anesthesia and pain medicine Vol.13 No.1

Background: We investigated the effect of combination of nefopam and remifentanil under the hypothesis that nefopam would effectively prevent rocuronium-induced withdrawal response by blocking serotonin receptors and providing a synergistic or additional effect with remifentanil. Methods: After receiving Institutional Review Board approval, 76 patients aged between 20 and 65 years with American Society of Anesthesiologists physical statuses of I or II were randomly allocated to the control group and nefopam group. In the control group, 102 ml of 0.9% sodium chloride solution was infused one hour before surgery at 100 ml/h. In the nefopam group, 20 mg nefopam (2 ml) in 100 ml of a 0.9% sodium chloride solution was infused one hour before surgery at 100 ml/h. Rocuronium (0.6 mg/kg) was injected after the induction of anesthesia with remifentanil and propofol at target concentrations of 2.0 ng/ml and 3.0 mg/ml, respectively. The grades of rocuronium-induced withdrawal response were evaluated using a four-point scale. The hemodynamics and respiratory rates were recorded upon operating room arrival, after anesthesia induction, and one minute post-injection of rocuronium. Results: Two patients (nefopam group) were excluded due to incomplete infusion and side effects; thus, 74 patients were finally analyzed. The overall incidence of rocuroniuminduced withdrawal response was significantly lower in nefopam group (27.8%, n = 36) than in control group (60.5%, n = 38) (P = 0.005). Conclusions: The combination of nefopam (20 mg) and remifentanil is more effective at reducing rocuronium-induced withdrawal response than remifentanil infusion alone with stable hemodynamics.

버섯을 이용한 젤리 제조 및 품질특성에 관한 연구

정기태,주인옥,최정식,최영근 한국식품영양학회 2001 韓國食品營養學會誌 Vol.14 No.5

영지, 표고, 눈꽃동충하초 그리고 번데기동충하초를 이용한 버섯젤리의 제조와 제품의 색도, 물성 및 기호도를 비교 조사하였다. 버섯 젤리 제조를 위한 추출액의 적정혼합비율을 선발한 결과, 영지버섯 젤리는 버섯추출액 85%, 대추추출액 10%, 황기추출액 5%를 혼합했을 때, 표고버섯 젤리는 버섯추출액 80%, 대추추출액 10%, 감초추출액 5%, 오미자추출액 5%를 혼합했을 때, 눈꽃동충하초와 번데기동충하초 젤리는 버섯추출액 05%, 대추추출액 10%, 감초추출액 5%를 혼합했을 때 가장 우수하였다. 젤화제 종류별로 버섯 추출액에 대한 응고 효과는 모든 버섯에 대해 carrageenan이 가장 효과적이었다 버섯 젤리의 색도는 carrageenan 첨가량에 따라 큰 차이가 없었고, hardness, gumminess, chewiness는 증가하는 경향이었다. 관능은 젤화가 완전히 이루어지면서 hardness가 낮은 carrageenan 0.6% 첨가가 가장 우수하였다. Mushroom jellies using extracts of Garnoderma lucidum, Lentinus edodes, Pacilomyces ten tenuipes and Cordyceps militaris were prepared, and Investigated the colors, texture and sensory characteristics of mushroom jellies. G. lucidum jelly mixed 85% mushroom, 10% jujube(Zizyphus jujuba Miller) and 5% hwanggi (Astragaslus membranaceus) extract, L. edodes jelly mixed 80% mushroom, 10% jujube, 5% gamcho( Glycyrrhiza uralensis) and 5% omija (Schizandrae chinensis Ruprecht) extract. and P. tenuipes and C. militaris jelly mixed 85% mushroom. 10% jujube and 5% gamcho extract were most effective in overall acceptability. The Jellying ability of carrageenan was better than other jelling agents. According to increase carrageenan content, color of mushroom Jellies were not effect. however hardness, gumminess and chewiness were increased. Sensory evaluation of mushroom Jellies were most preferable at the 0.6% carrageenan content.

IBM의 EA 프로젝트 수행사례 소개

정기태 한국EA학회 2004 한국EA학회 학술발표논문집 Vol.2004 No.11

컨셉 기획에서 디자인 적용까지(워크샵)

정기태 한국생활과학회 2019 한국생활과학회 학술대회 Vol.2019 No.5

Successful application of high-flow nasal cannula in a patient with postoperative respiratory disturbance after bilateral sagittal split ramus osteotomy surgery - A case report -

정기태,지인국,김상훈 대한마취통증의학회 2018 Anesthesia and pain medicine Vol.13 No.3

Bilateral sagittal split ramus osteotomy (BSSRO) is generally indicated for mandibular setback, to improve occlusion, masticatory function, and aesthetics by altering the mandibular position. However, BSSRO narrows the pharyngeal airway and increases airway resistance, resulting in postoperative respiratory disturbances during emergence from anesthesia. Oxygen delivery system via high-flow nasal cannula (HFNC) has been known to improve airway patency and oxygenation via low-level positive pressure as well as reduce the respiratory load. We report a case of postoperative respiratory disturbance, following a large mandibular setback, despite nasotracheal extubation in the fully awake patient. Respiratory disturbance was successfully controlled after oxygen delivery via HFNC until self-respiration was completely restored. Therefore, the use of HFNC may facilitate the control of postoperative respiratory disturbances induced by anatomical changes in upper airway after BSSRO surgery.