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식물성 질소원의 보충이 면양에 의한 볏짚의 소화율에 미치는 영향
이희섭,강희신 ( Hee Seob Lee,Hi Shin Kang ) 한국축산학회 1980 한국축산학회지 Vol.22 No.2
Three Corridale male sheep were fed each of the three diets; Acacia leaf hay alone (AL), chopped rice st raw plus near isonitrogeneous quantity of Soybean oil meal (RS) or Acacia Leaf Hay(RA) according to a Latin square design to studs the effect of supplemental nitrogen on the digestibilities of nutrients and the voluntary intake of rice straw. The results obtained from the above trial were summarized as follows: (1) The voluntary feed intake of acacia leaf hay was found to he 935g/day and its digestibility of dry matter, crude protein and crude fibre were 51.8, 46.0 and 52.0% respectively. (2) Although the total UM intake were not affected by the supplemental nitrogen sources, the intake of chopped rice straw by the sheep at the RS was 11.7% higher thar that of RA. (3) The crude protein intake of sheep at the AL was higher (p. 05) than those of RS and RA. The crude protein digestibility of RS, however, was higher than those of AL and RA as much as 71.7% and 64.2%. (4) Despite the trend that the liber intake of sheep fed chopped rice straw, RS and RA, were higher than that of AL as much as 49.3% and 64.3% the digestibility of crude fiber showed no significant difference among the treatments. The difference between the RS and AL., however, was significant at level of 10% probability. The total digestible nutrients of chopped rice straw was calculated to be 50% in DM basis by employing the TDN value of known Soybean oil meal and Acacia leaf hay.
이희섭,김상운(Sang Woon Kim),이수정(Soo Jung Lee),심민철(Min Chul Shim),권굉보(Koing Bo Kwun) 대한두경부종양학회 1995 대한두경부 종양학회지 Vol.11 No.1
We analyzed the results of ethanol sclerotherapy in 47 patients with cystic thyroid lesion. Cytologic study showed all of the lesions to be benign. The patients were followed clinically and ultrasonically I month and 3 or more months after ethanol sclerotherapy. If the cystic lesions recurred, repeated treatment was offered. In 4 patients with pure cystic lesion, all of the patents had almost total resolution of the cystic lesions. In 43 patients with mixed cystic lesion, 16(37.2%) patients had almost total resolution of the cystic lesions, 10(23.3%) patients showed a decrease' in the cystic lesion of <50%, but 11(25.6%) patients it did not change in size. Overall, in 30(63.8%) patients the cystic lesion decreased in size. Eleven patients who were not effective by sclerotherapy or follicular proliferation by cytology were converted to surgery. Although no severe complication were observed, there were complication of severe pain in I patient and a drunken feeling in I patient. If the malignancy must be excluded by repeated cytologic examination of aspirated fluid, we consider instillation of ethanol into the cystic lesions of the thyroid to be a simple, safe, economical and effective treatment.
해류를 이용한 해양쓰레기 처리시설 계획방안 -인천광역시 강화군 여차리 일대 환경계획안-
이희섭(Lee, Hee-Seop),이석주(Lee, Suk-Ju),이명아(Lee, Myung-A) 한국주거학회 2019 한국주거학회 학술대회논문집 Vol.31 No.2
Global warming and environmental pollution have become a serious social issue. Also, various waste disposal problems are inevitable. In other words, since these wastes can contaminate and invade people"s quality of life and their homes, there is a great need for people to solve environmental problems and solve the waste issues. In particular, marine debris has become more than just water and environmental pollution, polluting our quality of life and our communities. The absence of facilities that only deal with marine debris is serious, but simply waste management facilities must be properly planned and implemented. In other words, it is necessary to accurately understand the needs of the residents and to understand and approach on the cultural level and on the basis of lifestyle. Therefore, this study aims to plan marine debris disposal facilities using the characteristics of ocean currents. In order to plan the marine debris disposal facility, it is necessary to first evaluate the residential environment and the degree of damage of residents and fishermen near the coastline where garbage is collected due to currents in Korea. And it is necessary to maximize the processing capacity by calculating scientific evidence using currents. The marine debris disposal facilities utilizing these currents will ultimately have a great meaning to preserve the global environment, and will protect the foundations of our lives and protect the clean environment that will be passed down to future generations.
유산균 발효 마늘 추출물의 oleic acid로 유도된 비알코올성 지방간에 대한 개선 효과
이희섭(Hee-Seop Lee),임원철(Won-Chul Lim),최지휘(Ji-Hwi Choi),유희종(Heui-Jong Yu),김기호(Ki-Ho Kim),이승현(Seung-Hyun Lee),조홍연(Hong-Yon Cho) 한국식품과학회 2014 한국식품과학회지 Vol.46 No.6
본 연구에서는 oleic acid로 유도시킨 비알코올성 지방간 HepG2 세포 모델을 활용하여 LAFGE의 비알코올성 지방간 개선 효과를 검토하고 RT-PCR과 Western blot으로 메카니즘을 해석하였다. LAFGE는 1 mg/mL 농도에서 NFGE보다 세포 내 지방축적을 약 1.5배 저해하였다. Fig. 5에 나타낸 바와 같이 LAFGE는 FAT/CD36 mRNA 발현을 감소시켜 세포 내로 유입되는 지방산의 양을 감소시켰으며, PPARα와 CPT-1의 mRNA 발현을 증강시킴으로써 지방산의 베타-산화를 촉진시켰다. 또한 LAFGE는 지방합성을 촉진하는 전사인자인 SREBP-1c와 그의 조절을 받는 FAS의 mRNA 발현 수준을 oleic acid 처리시보다 각각 51%와 35% 까지 크게 감소시켰다. 뿐만 아니라 LAFGE는 농도의존적으로 SREBP-1c와 FAS의 단백질 발현도 감소시켰다. 이 결과들은 LAFGE가 oleic acid처리에 의해 유도된 HepG2 세포 내의 지방 축적을 개선할 수 있음을 시사하였다. In this study, the ameliorating effects of lactic acid-fermented garlic extract (LAFGE) on non-alcoholic fatty liver were investigated using oleic acid-induced steatotic HepG2 cells. The ameliorating mechanism was analyzed by RTPCR and Western blot. Treatment with 1 mg/mL LAFGE decreased intracellular lipid accumulation approximately 1.5-fold, compared to that achieved with non-fermented garlic extract. LAFGE reduced fatty acid influx into hepatocytes through down-regulation of FAT/CD36 mRNA expression in the steatotic HepG2 cells. PPARα and CPT-1 mRNA expression was significantly up-regulated by LAFGE treatment of HepG2 cells as a consequence of activation of beta oxidation. Additionally, the treatment with 1 mg/mL LAFGE highly down-regulated mRNA expression of SREBP-1c and FAS to 51% and 35%, respectively. LAFGE showed concentration-dependent down-regulation patterns in protein expression of SREBP-1c and FAS, as determined by Western blot. These results suggest that LAFGE treatment improves hepatic steatosis triggered by the imbalance of hepatic lipid metabolism owing to oleic acid treatment.