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들현호색으로부터 Berberine과 Coptisine의 분리 및 함량분석
이향이,김종원,Lee, Hyang-Yi,Kim, Chong-Won 한국생약학회 1999 생약학회지 Vol.30 No.3
Corydalis Tuber has been used in traditional medicine for an analgesic, antispasmodic and gastric ulcers. For the quality control on this drug, isolation and quantitative determination of berberine and coptisine from Corydalis ternata Nakai (Papaveraceae) has been conducted by using HPLC method. Berberine and coptisine in quarternary alkaloidal fraction from the crude drug were separated on silicagel column using a $CHCl_3:MeOH\;(85:15)$ and $CHCl_3:MeOH:H_2O\;(70:30:4)$ as an eluent, and the average contents were about 0.93 and 0.36%.
이향수(李享修) 한국지역정보화학회 2011 한국지역정보화학회지 Vol.14 No.1
그동안 지식관리의 주된 화두는 지식공유나 활용에 치중해 있었으며, 상대적으로 지식획득이나 축적에 대한 관심은 적었다고 할 수 있다. 그러나 지식의 획득과 축적을 기반으로 공유나 활용 등의 기타 지식활동이 이루어진다는 점에서 지식획득과 축적활동이 가지는 의미는 매우 크다. 본 연구에서는 지방정부 공무원들을 대상으로 하여 지식획득 및 지식축적 활동의 정도를 분석하였다. 연구방법은 설문조사를 통한 양적접근방법과 심층면담을 통한 질적 접근을 병행하여 표준화된 설문조사만을 통해서는 밝혀내기 어려운 공무원들 지식활동의 현실을 분석하고 있다. 분석 결과 지방정부 공무원들의 지식획득 및 축적활동은 보통수준이며, 형식적이며 소극적인 지식활동을 하는 것으로 나타났다. 이러한 연구결과를 바탕으로 정부조직의 지식활동에 있어서의 정책적 시사점을 논의하였다. Knowledge acquisition and accumulation have received very little attention in the study of knowledge management, unlike knowledge sharing and utilization. For an organization to generate and preserve a competitive advantage, it is vital that its knowledge be acquired and stored. This study analyzes, by quantitative approach of surveys and qualitative approach of in-depth interviews, the degree of activities of knowledge acquisition and accumulation for the employees of a local government organization. The results show that the employees of a local government are not aggressively involved in knowledge acquisition and accumulation activities. Lessons and implications of this study for management leadership are presented.
이향이,김종원,Lee, Hyang-Yi,Kim, Chong-Won 한국생약학회 2000 생약학회지 Vol.31 No.1
Impatiens textori Miquel (Balsaminaceae) is an annual plant growing in most parts of Korea. The herb of this plant has been used for the external application of snake poison and the bruise. Previous investigations conducted with the herbs have demonstrated it to contain three flavones and three flavone glycosides. Continuing to previous reports, quercetin, kaempferol and acacetin $7-O-{\beta}-D-glucoside$ were isolated from the herbs of this plant.
이향이,김종원,Lee, Hyang-Yi,Kim, Chong-Won 한국생약학회 1997 생약학회지 Vol.28 No.4
Berberis amurensis Ruprecht(Berberidaceae) is a medicinal plant indigenous to the middle and northern part of Korean peninsula. The woody parts of this plant have been used for the ocular, peptic and intestinal disorders. The stems of this plants were extracted with MeOH and the MeOH extract was partitioned between organic phases and water layer, successively to fractionated quarternary alkaloids. The acetone-soluble part of guarternary alkaloidal fraction had antibacterial activities and it contained four protoberberine alkaloids such as palmatine(I), Berberine(II), Jatrorrhizine(III) and coptisine(IV), and one aporphine alkaloid, magnoflorine(V). Although the isolations of the compounds I, II, IIII, IV and V from different sources were reported, this is the first report that Berberis amurensis contained the compounds. When the contents of compound I(palmatine) and II(berberine) were quantified and compared with those of other plant parts, cortex contained higher palmatine and berberine than any other part of the plant.