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섬망 치료에서 Aripiprazole과 Haloperidol의 효과 : 무작위 개방 연구
이준영(Joonyoung Lee),조현영(Hyunyoung Jo),정운선(Unsun Chung),이병대(Byung Dae Lee),이양현(Yanghyun Lee),정성훈(Sunghoon Jeong) 대한생물치료정신의학회 2007 생물치료정신의학 Vol.13 No.2
Objectives:Delirium is a common condition frequently seen in consultation-liaison psychiatry. Antipsychotic drugs are the primary treatment for symptoms of delirium. Typical antipsychotics, especially haloperidol, have been used as the mainstay of pharmacological treatment of delirium. With the introduction of atypical antipsychotics, the clinical usefulness of these medication has also been investigated for delirious patients. The purpose of this randomized, open-clinical trial is to compare the clinical efficacy and tolerability of haloperidol and aripiprazole for the treatment of delirium. Method:45 patients with a diagnosis of delirium were enrolled between July 2005 and May 2007 in this study. They were randomly assigned to be treated with a flexible-dose regimen of haloperidol or aripiprazole. The Korean version of Delirium Rating Scale(K-DRS) and other measures related with delirium had been used repeatedly until the K-DRS score reached 12 or less which we defined as the criteria for recovery from delirium. 22 subjects in haloperidol group and 19 in aripiprazole group completed the study. Results:The mean dosage of antipsychotics for delirium was 3.0±1.6㎎ of haloperidol and 5.5±1.5㎎ of aripiprazole which was relevant to 150.5±83.6㎎ and 73.7±20.9㎎ of chlorpromazine respectively. Aripiprazole was effective to subside the delirium symptoms at less dosages than haloperidol. There were no significant group differences in the score of K-DRS, K-DRS-R-98 and MMSE-K at baseline as well as final assessments. There was no significant difference in duration of treatment and clinical improvement between the groups. Most of the patients were well tolerated to the adverse events of each antipsychotic drug but only two patients in haloperidol group showed extrapyramidal symptom. Conclusion:Aripiprazole may be more useful than haloperidol in patients with delirium because of its safety and low dose effectiveness, especially in aged patients. Further double-blind placebo-controlled studies with a large sample size will be necessary.
외국인 학습자의 한국어 능력 평가 방안 연구 : 2급 수준 학습자를 중심으로
이준영(Lee JoonYoung) 한국문화융합학회 2020 문화와 융합 Vol.42 No.2
이 연구는 효과적인 외국인 학습자의 한국어 능력 평가 방안을 마련하는 것을 목적으로 한다. 연구의 결과 많은 수의 학습자를 대상으로 이루어지는 대다수의 한국어 교육 현장의 특성상, 영역 통합 평가를 통해 이루어지는 정기 평가, 학습자 스스로 자신의 문제를 파악하고 해결하는 자기 평가, 교사의 밀착형 평가 방식인 1대1 평가, 함께 공부하는 친구를 위해 수행하는 동료 평가 등을 복합적으로 활용한 평가 방식의 적용이 유효하다는 결과를 얻을 수 있었다. 특히 1대1 평가의 경우, 학습자 개개인의 상황에 맞춘 평가 방식을 구현해야 하기에 교사와 학습자의 관계가 친밀하지 않으면 학습자의 문제 상황을 파악하는 것에 한계가 있다는 점을 발견할 수 있었다. 그리고 같은 이유로 인하여 특정 지어진 일관된 평가 양식을 마련하는 것이 힘든 점 또한 해당 평가 방식의 한계점으로 들 수 있었다. 그리고 이러한 한계를 극복하기 위해서는 다양한 평가 방식을 복합적으로 적용하는 것이 필요하다는 결론을 도출할 수 있었다. 이 연구는 그동안 이론적 차원에서 연구되어 온 생태적 한국어 능력 평가 방안을 실제 교육 현장에 적용해보고, 이를 통해 그 한계점을 극복할 수 있는 방안으로써 복합 평가의 방식이 유효하다는 것을 검증하였다는 점에서 그 의의를 찾을 수 있다. The purpose of this study was to develop an effective plan of Korean proficiency assessment for foreign learners of the Korean language. The result showed that 1:1 assessment is not appropriate as it is presently conducted st most Korean language education sites. Thus, regular assessments through integrated sectional tests, self-assessment whereby learners identify and solve questions on their own, and assessment methods using a colleague-based test to perform for study mates were more effective to apply. This study found, in particular, that the lack of a close relationship with the teacher limits the identification of a learner s problem situation in 1:1 assessment, because the assessment must correspond to the learner’s individual circumstances. Similarly, the difficult of devising a consistent, critical assessment method was another limitation of the test, and it was necessary to apply various assessment methods to overcome this limitation depending on the result. This research is significant in the following ways. It applied ecological Korean proficiency assessment, which has been researched only at the theoretical level, at an actual educational site. This study also verified the effectiveness of a complex assessment method as a means to overcome assessment limitations.