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뇌졸중 후 중추성 통증에 대한 통증관리가 재활에 미치는 효과
이두익(Doo Ik Lee),김건식(Keon Sik Kim),채호승(Ho Seung Chae),최도영(Do Young Choi),이재동(Jae Dong Lee),이윤호(Yun Ho Lee),박재경(Jae Kyung Park),김수영(Su Young Kim) 대한통증학회 2002 The Korean Journal of Pain Vol.15 No.1
N/A Background: Central poststroke pain (CPSP) can occur as a result of lesion or dysfunction of the brain from stroke and may cause many difficulties in social activities and daily life, especially in the rehabilitation program. In this study, we evaluate the clinical effectiveness of pain management for CPSP patients during their rehabilitation. Methods: Thirty patients who had suffered from CPSP, as diagnosed by their typical pain characteristics of central pain from stroke, were included in the stud. We investigated pain intensity through the visual analogue scale (VAS), and improvements of mobility and rehabilitation through for 3 weeks. Modalities of pain treatment were sympathetic nerve block, antidepressants, anticonvulsants and/or a-2 agonists. Results: VAS pain scores improved significantly (P < 0.05) from 7.9 ± 1.4 to 4.7 ± 1.6 with pain treatment. MBI and RS scores improved significantly (both, P < 0.05) from 61.4 ± 13.6 to 85.0 ± 13.9 and from 3.3 ± 0.7 to 2.5 ± 0.7, respectively, with pain treatment. Conclusions: The rehabilitation scores, MBI and RS, were improved significantly in conjunction with an improvement of VAS pain score. Furthermore, we active pain management of CPSP patients could facilitate their rehabilitation from stroke.
무작위 대조 이중맹검 시험을 통한 봉독 약침의 류마티스 관절염 치료 효과 연구
이상훈,홍승재,김수영,양형인,이재동,최도영,이두익,이윤호,Lee, Sang-hoon,Hong, Seung-jae,Kim, Su-young,Yang, Hyung-in,Lee, Jae-dong,Choi, Do-young,Lee, Doo-ik,Lee, Yun-ho 대한침구의학회 2003 대한침구의학회지 Vol.20 No.6
Objective : This study was performed in order to evaluate the effect of bee venom therapy on rheumatoid arthritis by randomized controlled double blind method. Methods : RA patients were recruited and divided into an experiment group and a control group by random selection. As a double blind test, the experiment group was treated with bee venom injection on acupoints, and the control group was treated with normal saline injection on acupoints twice a week for 8 weeks. Tender joint count, swollen joint count, morning stiffness, pain, health assessment questionnaire, ESR, and CRP were estimated and analyzed at baseline, and at 1 month and 2 months after bee venom therapy. Results : Compared to the control group, the experiment group showed significant decrease in tender joint count, swollen joint count, morning stiffness, and health assessment questionnaire after 2 months. Pain, ESR and CRP showed significant decrease in the experiment group after 1 & 2 months. Conclusions : These results suggests that bee venom therapy could be an effective method in the treatment of patients with rheumatoid arthritis.
뇌졸중 후 중추성 통증 환자에 대한 동서협진이 진통과 재활에 미치는 영향
이현종,김수영,이상훈,서동민,이두익,김건식,이재동,이윤호,양형인,박재경,최도영,Lee, Hyun-jong,Kim, Su-young,Lee, Sang-hoon,Seo, Dong-min,Lee, Doo-ik,Kim, Keun-sik,Lee, Jae-dong,Lee, Yun-ho,Yang, Hyung-in,Park, Jae-kyung,Choi, Do-young 대한침구의학회 2003 대한침구의학회지 Vol.20 No.2
Purpose : In order to study the effectiveness of East-West pain treatment on central poststroke pain(CPSP), we evaluated its effect on alleviation of pain and rehabilitation of CPSP patients who were treated with eletroacupuncture and west pain treatment for four weeks. Methods : Twenty four patients diagnosed by their pain characteristics of central pain form stroke were treated with sympathetic nerve block, gabapentin, amitriptyline, and electroacupuncture for four weeks. Pain intensity through the visual analogue scale(VAS), and improvements of mobility and rehabilitation through the modified Barthel index(MBI) and Rankin scale(RS), respectively, before and after pain treatment were also assessed. Results : VAS pain scores were significantly improved from $7.7{\pm}1.7$ to $4.4{\pm}2.0$ with pain treatment(p<0.05). In accordance with improvement of ain scores, RS and MBI scores ere also improved from $2.88{\pm}0.95$ to $2.13{\pm}1.01$ and from $83.0{\pm}16.9$ to $94.7{\pm}9.5$(p<0.05), respectively, with pain treatment(p<0.05). Conclusions : It was suggested that the active pain treatment was contributed to the rehabilitation of CPSP patients, resulting in improvement of quality of life of CPSP patients. Futhermore, East pain treatment in combination with West pain treatment may be useful modality to alleviate CPSP.
대장 내시경 후 발생한 장중첩증을 동반한 Peutz - Jeghers 증후군
이재동(Jae Dong Lee),박경식(Kyeong Sik park),정보윤(Bo Yun Jung),정성균(Seong Kyoon Cheong),조준환(Jun hwan Jo),유승박(Seung Park Yoo),김휘정(Hwi Jung Kim),김열홍(Yul Hong Kim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.4
N/A Peutz-Jeghers syndrome has three cardinal features, gastrointestinal polyposis, mucocutaneous pigmentation and autosomal dominant inheritance. This syndrome is clinically important because of the complication of gastrointestinal polyps, leading to abdominal pain, anemia due to gastrointestinal bleeding, intussusception, and a certain risk of malignant change. We experienced a case of Peutz-Jeghers syndrome combined with intussusception after colonoscopy.
김여진,이재동,이윤호,Kim, Yeo-Jin,Lee, Jae-Dong,Lee, Yun-Ho The Korean AcupunctureMoxibustion Medicine Society 2007 대한침구의학회지 Vol.24 No.2
목적 : 본 연구는 화피의 연골 보호 및 소염 진통 작용을 알아보고, 화피를 이용한 관절염치료 약침액 개발의 기초자료를 얻기 위해 고안되었다. 방법 : In vitro에서는 토끼 무릎관절에서 배양된 연골조직에 5ng/ml IL-1${\alpha}$ 처리 후, 화피의 연골보호 효과, 연골세포에 대한 독성을 조사하였다. In vivo에서는 토끼 무릎관절내 collagenase를 주입, CIA 유발 후, 28일간 매일 토끼의 구강으로 화피, 증류수, CEX를 투여하였으며, 연골보호, 소염, 진통에 대한 측정을 하였다. 결과 : 화피는 proteoglican 및 collagen분해 억제, MMPs 활성 억제로 연골 보호 효과가 있었으며, 연골 세포에 대한 독성이 없었다. 소염작용은 PGE2 생산 억제 및 COX-2발현 억제, carrageenan 유발 쥐 모델에서의 부종 억제로 확인되었다. 진통작용은 tail flick test에서의 latency time 증가, formalin test에서의 염증성 통증억제로 나타났다. 결론 : 화피가 퇴행성관절염에 대한 연골 보호 효과 및 소염 진통 작용이 있으므로, 이를 근거로 약침액을 개발 응용하면 퇴행성관절염 치료에 활용될 수 있다고 사료된다.
자하거(紫河車) 약침(藥鍼) 제제(製劑)에 대(對)한 고찰(考察)
이상길,이재동,고형균,박동석,이윤호,강성길,Lee, Sang-Keel,Lee, Jae-Dong,Koh, Hyung-Kyun,Park, Dong-Suk,Lee, Yun-Ho,Kang, Sung-Keel 대한침구의학회 2000 대한침구의학회지 Vol.17 No.1
Hominis Placenta has been used as a medicinal stuff for a long time in Oriental Medicine. And further, aqua-acupuncture solution of Hominis Placenta has produced in South Korea recently. Bibliographical study was carried on to investigate the nature of Hominis Placenta and possible indications by aqua-acupuncture as well. The nature of Hominis Placenta is warm and its taste sweet-salty. It is non-poisonous. It has correspondence to the meridians of lung, liver and kidney. Hominis Placenta is mainly effective on recuperation of infirmity and the disease related to infirmity. Aqua-acupuncture solution of Hominis Placenta can be applied to the disease as chronic hepatitis, liver cirrhosis, asthma, pulmonary tuberculosis, sterility, insufficient lactation, degenerative change, neurasthenia and cerebrovascular disease.
김지훈,이재동,최도영,안병철,박동석,이윤호,Kim, Ji-Hoon,Lee, Jae-Dong,Choi, Do-Young,Ahn, Byung-Choul,Park, Dong-Suk,Lee, Yun-Ho 대한침구의학회 2000 대한침구의학회지 Vol.17 No.3
Chronic headache is one of the most common symptoms of outpatients. There are many approaches to treat chronic headache, but it is difficult to be resolved completely. So analgesics-addicted patients are increased in numbers. Acupuncture and ear-acupuncture have been used for relief headache. But it is not sufficient to compare the effect of acupuncture on several chronic headache groups. Thus we investigate the effect of acupuncture and ear-acupuncture on several chronic headache groups and analgesics-abused groups. We researched 36 patients who were treated at Department of Acupuncture & Moxibustion, Kyung Hee Medical Center from August 1998 to July 1999. The chronic headache patients were classified into tension-type headache group, migraine group and unclassified headache group by Guide of IHS. Each group was treated with acupuncture and ear-acupuncture. The effect was assessed through questionnaires and self-rating headache index.
암관련 봉독 연구에 대한 고찰-PubMed를 이용한 Medline 검색
윤형석,이재동,이윤호,Yun, Hyoun-Seok,Lee, Jae-Dong,Lee, Yun-Ho 대한침구의학회 2000 대한침구의학회지 Vol.17 No.4
Objective : To research the trends of the study related to bee venom and cancer, and to establish the hereafter direction of the study on bee venom herbal acupuncture. Method : We searched in PubMed, with bee venom and cancer(in English, with abstract) Results : 1. We searched 28 Journals, 36 Papers. the frequency of Journals and Papers was as follows: Biochem Biophys Res Commun(4 Papers), FEBS Lett(3), Life Sci, Proc Natl Acad Sci USA, J Immunol(each 2), other 23 Journals(each 1). 2. The pattern of the study was as follows: Review article(3 Journals, 3 Papers), Epidemiologic study(1, 1), Experimental study(24, 32) In vivo 1, 1), In vitto(24, 31) 3. The involved components of bee venom were as follows: Melittin(20), Apamin(8), Phospholipase A2(3), Melittin & Phospholipase A2(3), Melittin& Tertiapin(1). 4. The involved cancer was as follows: leukemia(9), tumor(5), neuroblastoma(4), pituitary tumor and pheochromocytoma(each 3), lymphoma, astrocytoma, glioma and lung cancer(small cell carcinoma)(eacn 2), bladder carcinoma, pancreatic cancer, breast carcinoma, ovarian carcinoma and spuamous cell carcinoma(each 1) Conclusion : We concluded that the most frequent pattern of the study was in vitro experimental study with peptide components of bee venom and the most frequeni invovled cancer was leukemia.