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소아 만성 신부전 환자에서 발생한 위혈관 이형성증의 Hemoclipping에 의한 지혈 치료 1례
이윤진,김영미,김수영,박재홍,Lee, Yun-Jin,Kim, Young-Mi,Kim, Su-Young,Park, Jae-Hong 대한소아소화기영양학회 2003 Pediatric gastroenterology, hepatology & nutrition Vol.6 No.2
Angiodysplasia is the most common vascular abnormality of the gastrointestinal tract and probably the most frequent cause of recurrent lower intestinal bleeding in otherwise healthy elderly patients. Also, it is an important cause of hemorrhage in chronic renal failure observed in up to 19~32% of patients. Bleeding due to gastric angiodysplasia is treated by various endoscopic approaches, including argon and Nd : YAG laser photocoagulation, monopolar or bipolar electrocoagulation, heater probe, injection sclerotherapy, band ligation or hemoclipping. A 15-year-old boy, who had undergone hemodialysis for chronic renal failure for about 10 years, was admitted due to melena and progressive anemia. A gastroduodenoscopy revealed a cherry red and fern-like lesion with oozing on the posterior wall at junction of gastric body and fundus. Endoscopic hemoclipping therapy was performed. However, melena recurred four days later. Argon plasma coagulation and hemoclipping therapy were performed again. Since then, no recurrence of bleeding has been observed.
이윤진 ( Yun-jin Lee ),이은별 ( Eun-byeol Lee ),김현지 ( Hyeon-ji Kim ),양두화 ( Doo-hwa Yang ),김영준 ( Young-jun Kim ),안희덕 ( Hee-duk An ) 한방재활의학과학회 2021 한방재활의학과학회지 Vol.31 No.2
Objectives We evaluated the improving effects of Taeksa-tang (TST) using 3T3-L1 cells and C57BL/6 mice were fed on a high-fat diet. Methods The anti-radical activities of TST were studied using 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid). The content of total polyphenol was measured using Folin-Ciocalteu reagent, whereas aluminum chloride colorimetric method was used for the content of total flavonoid. Moreover, the factors related to lipid profile and the protein expressions such as β-oxidation and anti-oxidant enzyme were analyzed using serum and western blotting of 3T3-L1 cells. Additionally, we examined lipolysis through glycerol appearance in mouse adipose tissue. Results TST treatment showed strong free radical scavenging activities with half maximal inhibitory concentration and the presence of a amount of total polyphenol and total flavonoid. TST treatment significantly increased factors related to β-oxidation such as carnitine palmitoyl transferase-1 and uncoupling protein 2 via the phosphorlyation of liver kinase B1 (LKB1) and AMP-activated protein kinase (AMPK). Moreover, the protein expressions of anti-oxidant enzyme and lipolysis were significantly elevated by TST administration. In addition, TST supplementation lowered serum ma-londialdehyde, triglyceride, and total cholesterol levels compared with the control group. Taken together, these data suggest that TST treatment regulated lipid parameters via the increase of β-oxidation by LKB1-AMPK signaling pathway. Conclusions TST may have a potential remedy in the prevention and treatment of obesity. Therefore, this study may provide the scientific basis for TST use. (J Korean Med Rehabil 2021;31(2):1-14)
임상간호사의 욕창분류체계와 실금관련피부염에 대한 지식과 시각적 감별 능력
이윤진(Lee, Yun Jin),박승미(Park, Seungmi),김정윤(Kim, Jung Yoon),김철규(Kim, Chul-Gyu),차선경(Cha, Sun Kyung) 한국간호과학회 2013 Journal of Korean Academy of Nursing Vol.43 No.4
Purpose: This study was done to compare clinical nurses’ knowledge and visual differentiation diagnostic ability for the pressure ulcer classification system (PUCS) and incontinence-associated dermatitis (IAD). Methods: A convenience sample of 602 nurses took the pressure ulcer classification system and incontinence-associated dermatitis knowledge test (PUCS & IAD KT) and completed the visual differentiation tool (VDT), consisting of 21 photographs with clinical information. Results: The overall mean score for correct answers was 14.5 (±3.2) in PUCS & IAD KT and 11.15 (±4.9) in PUCS & IAD VDT. Incorrect responses were most common for statements related to stage III, IAD for PUCS & IAD KT, and suspected deep tissue injury (SDTI), unstageable, and stage III for PUCS & IAD VDT. Significant correlations were found between PUCS & IAD KT and VDT (r=.48, p<.001). Factors affecting scores for PUCS & IAD VDT were PUCS & IAD KT, frequency of pressure ulcer, IAD management and participation in wound care education programs. Conclusion: Results indicate that nurses have an overall understanding of PUCS & IAD, but low visual differentiation ability regarding stage III, SDTI, and unstageable ulcers. Continuing education is needed to further improve knowledge and visual differentiation ability for PUCS & IAD.
이윤진(Yun Jin Lee),김영미(Young Mi Kim),남상욱(Sang Ook Nam),김학진(Hak Jin Kim) 대한소아신경학회 2003 대한소아신경학회지 Vol.11 No.2
중추신경계의 특발성 혈관염(PACNS)은 전신성혈관염의 한가지로 호발연령은 중년층의 성인이며, 임상양상은 두통, 일사적인 허혈성 발작, 경련에서 뇌증까지 다양하다. 뇌 자기공명영상과 혈관조영촬영으로 진단적 접근을 할 수 있고, 병변부위의 조직검사상 혈관염 소견으로 확진할 수 있다. 저자들은 소아에서 반복적인 편마비와 의식소실이 동반된 중추신경계의 혈관염을 국내에서 처음 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. 급성 뇌졸중의 조기 치료 및 합병증의 적극적인 예방으로 유병률을 감소시킬 수 있으므로 소아에서 잦은 심한 두통과 국소적인 신경학적 결함이 동반될 시엔 항상 PACNS의 가능성을 고려해야 하겠다. Primary angiitis of the CNS(PACNS), also known as isolated angiitis of the CNS, is an idiopathic vasculitis confined to the CNS and it primarily occurrs to middle aged adults. Neurologic manifestations include headache, focal seizure, and progressive, behavioral or multifocal neurologic impairments. A 20-month-old boy was presented with recurrent right-sided hemiplegia and loss of consciousness. Brain MRI revealed focal T2 hyperintensely enhanced lesions involving left lentiform nucleus and caudate nucleus with no mass effects. Cerebral angiogram disclosed multifocal stenosis in both middle cerebral arteries and left posterior cerebral artery. The child was treated with prednisone alone since he was diagnosed as IACNS. He was asymptomatic with a normal neurologic examination and continued on prednisone therapy. Therefore, it is concluded that children who have frequent or severe headache or focal neurologic deficits should be carefully evaluated and those meeting criteria of IACNS should be treated aggressively.
이윤진 ( Yun Jin Lee ),김영미 ( Young Mi Kim ),박희주 ( Hee Ju Park ),김건일 ( Gun Il Kim ),송수복 ( Su Bock Song ) 대한소아알레르기호흡기학회 2002 소아알레르기 및 호흡기학회지 Vol.12 No.3
호흡기 감염을 오래 앓으면서 영양 섭취가 거의 되지 않았던 상태에서 홍역 환자와의 접촉으로 홍역 바이러스에 감염되었고, 이후 쇠약한 전신 상태가 지속되면서 기흉과 종격동기흉까지 동반된 홍역 바이러스 폐렴이 발병하였으며, 계속된 발열과 마른 기침으로 입원 치료받던 중 주폐포자충 폐렴으로 진단되어 치료된 증례 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Measles is a highly infectious virus that attacks almost all susciptible individuals. In both the prevaccination and postvaccination areas, severe illness has been associated with the following factors:young age, malnutrition, crowded conditions, unvaccin
이윤진 ( Yun Jin Lee ),이상규 ( Sang Gyu Lee ),유창훈 ( Chang Hoon You ),김봄결 ( Bomgyeol Kim ),김태현 ( Tae Hyun Kim ) 한국병원경영학회 2020 병원경영학회지 Vol.25 No.3
Purposes: The purpose of this study was to identify the factors related to the long-stay hospitalization of dementia patients aged 65 years or older who had received inpatient care at geriatric hospitals according to the minute facility characteristics and patient features. Methodology: This study was conducted on 317,353 cases of 1,512 geriatric hospitals using the Health Insurance Review and Assessment Service dataset. The data collected were processed using the SAS Enterprise Guide 4.3 for descriptive statistics, the chi-square test, and the binary logistic regression analysis. Findings: As a result of the study, in the facility characteristics of geriatric hospitals, the long-stay hospitalization of the aged with dementia were found to be related to the type of facility establishment, the number of hospital beds, the number of medical specialists, the number of nursing personnel, and the number of geriatric hospitals by region and province. In the personal features of patients, the long-stay hospitalization was found to be associated with the gender, age, insurance, and the patient classification groups. Practical Implication: Considering the results of this study, it seems that securing the sufficient medical personnel in a geriatric facility, providing the good quality medical services, and preparing the appropriate discharge plan can reduce the unnecessary long-stay hospitalization and spend the medical expenses for the older patients.