시판 두부 제조 공정 중의 Microflora Profile 분석

이설희 ( Sul Hee Lee ),박영서 ( Young Seo Park ) 한국산업식품공학회 2012 산업 식품공학 Vol.16 No.3

Microflora profiles including total bacteria, psychrophiles, and spore-forming bacteria in manufacturing process steps of tofu were analyzed to elucidate the cause of microbial contamination. The viable cell numbers of total bacteria in soybean and packed tofu were 4.75 and 2.53 log CFU/g, respectively. The viable cell number of psychrophiles in soybean was calculated to 3.55 log CFU/g, and reduced to 0.78 log CFU/g by heating during the soymilk preparation step, and was not detected in the final product. The viable cell numbers of spore-forming bacteria, the major bacteria in soymilk, in soybean and packed tofu were 1.75 and 0.58 log CFU/g, respectively. Total twenty nine genus and seventy species of bacteria were isolated and identified in the manufacturing process of tofu, from soybean to final packed tofu. The major bacteria existed in the soybean, soymilk, forming belt, sum-mul plate, knife, packed tofu before sterilization, and packed tofu after sterilization were identified as Bacillus spp., Lysinibacillus bronitoleran, Acinetobacter spp., Bacillus spp., Acinetobacter spp., Acinetobacter spp., Staphylococcus spp., respectively.

3-자유도 병렬형 기구에서의 새로운 순 기구학 해석

이설희(Lee Sul Hee),연제성(Je Sung Yeon),권오흥(Ohung Kwon),박종현(Jong Hyeon Park) 대한기계학회 2006 대한기계학회 춘추학술대회 Vol.2006 No.11

Real-time control is an important factor in developing biped robots, and prompt analysis of forward kinematics is an advantage for real-time control. The objective of this paper is to find a new way to analyze forward kinematics in 3-DOF parallel structure. In this paper, we provide easy mechanistic method for solving forward kinematics. This method is simple unfolding of the equation, and there is only one solution needed. When solve the forward kinematics assume that fixed plate and moving plate as a manipulator. And connection part of linear actuator and fixed plate is universal joint. So there is only roll and pitch rotation. Therefore we can use cosine rule to solve roll rotation angle between two endpoint of linear actuator and triangular plate of center of fixed plate. And using fact, that distance of end-effector of each linear actuator, that is connected moving plate, and end-effector is constant, pitch rotation angle can be found.

Type 2 inflammation beyond skin

이설희 ( Sul Hee Lee ) 대한피부과학회 2023 대한피부과학회 학술발표대회집 Vol.74 No.2

복막투석 환자의 예후를 예측하는 인자로서 총 단백 복막 청소율의 의의

이설희 ( Sul Hee Yi ),이호영 ( Ho Young Lee ),김정현 ( Jung Hyun Kim ),정재면 ( Jae Myun Jung ),권순효 ( Soon Hyo Kwon ),전진석 ( Jin Seok Jeon ),한동철 ( Dong Cheol Han ),노현진 ( Hyun Jin Noh ) 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.6

Purpose: It has been reported recently that peritoneal protein clearance (Pcl) is a marker of endothelial dysfunction and cardiovascular disease in peritoneal dialysis patients. We evaluated whether baseline or longitudinal follow-up Pcl is a factor to consider in predicting the outcome in peritoneal dialysis patients for the follow-up period. Methods: Patients who initiated continuous ambulatory peritoneal dialysis at our center from September 1994 to January 2006 and had a baseline peritoneal equilibration test, measurement of dialysis adequacy, and 24-h dialysate Pcl (24hr dialysate protein loss/ [serum albumin/0.4783]) were included. Demography, comorbidities, and biochemical data were retrospectively collected. Follow-up was until death or the end of the period studied (November 2009). Results: A total of 203 patients (56% men, mean age 55.0±12.5; 55.2% with diabetes; 22.2% with cardiovascular disease) were included. The mean follow up period was 38 months (3-170 months). Baseline Pcl was 128.2 ml/day. Follow up data of Pcl were not changed from baseline period. Cox`s analysis revealed the predictors of mortality (and technical failure) were age and diabetes mellitus but not dialysate/plasma creatinine ratio (D/Pcr) and Pcl. On multivariate analysis, Pcl was negatively correlated with serum albumin and triglyceride and positively correlated with D/Pcr and peritoneal creatinine clearance. Conclusion: Our study showed that the changes in Pcl over time were not significant from baseline up to 53 months. Neither baseline nor mean Pcl during the follow-up period were independent predictors for technical or patient survival.

어루러기에서 경구 아졸계 항진균제의 치료 효과 비교: 체계적 문헌고찰 및 메타분석

권륭 ( Ryung Kwon ),이설희 ( Sul Hee Lee ),박영립 ( Young Lip Park ),이상훈 ( Sang Hoon Lee ) 대한피부과학회 2021 대한피부과학회지 Vol.59 No.5

Background: In pityriasis versicolor, systemic antifungal agents may be indicated for widespread or refractory lesions rather than topical treatment. Oral ketoconazole is an effective treatment for pityriasis versicolor. To our knowledge, this is the first meta-analysis to compare antifungal agents one-to-one. Objective: To compare the effectiveness of oral azole antifungal agents (fluconazole, itraconazole, and ketoconazole) one-to-one in pityriasis versicolor. Methods: A computerized search was performed in different databases, including PubMed, Cochrane, EMBASE, OVID Medline, KoreaMed, KISS, and MedRIC. Seven randomized controlled trials were included. Further, statistical analyses of the extracted outcome data from the studies were performed using Rex Software (ver. 3.0.1). Results: A total of 1,828 records were identified. The results of the meta-analysis including seven studies revealed no significant differences in the mycological cure rates between fluconazole and ketoconazole (risk ratio [RR]: 1.01, 95% confidence interval [CI]: 0.93∼1.09, p=0.8246), fluconazole and itraconazole (RR: 1.14, 95% CI: 0.81∼1.60, p=0.4512), and ketoconazole and itraconazole (RR: 1.07, 95% CI: 0.96∼1.20, p=0.2265). Conclusion: There was no superiority in the therapeutic effect of any drug among the oral azole antifungals used in pityriasis versicolor. (Korean J Dermatol 2021;59(5):370∼378)

병원간호사의 직장 내 괴롭힘에 대한 태도 양상

윤은자(Yeun, Eun-Ja),이설희(Lee, Sul-Hee),고정아(Ko, Jung-A),정계숙(Jeong, Gay-Suk),신호연(Shin, Ho-Yeon),서미정(Seo, Mi-Jeong),강혜정(Kang, Hye-Jung),유미진(You, Mi-Jin) 한국웰니스학회 2017 한국웰니스학회지 Vol.12 No.2

본 연구는 병원간호사의 직장 내 괴롭힘에 대한 태도 양상을 파악하고, 유형별 특성을 확인하기 위한 탐색적 연구이다. Q방법론을 적용한 본 연구는 서울 및 충북 소재 2곳의 상급종합병원에 근무하는 간호사 47명을 P표본으로 편의표집하여 이들이 38개의 Q표본을 9점 척도 상에 강제 분포하도록 하였다. 수집된 자료는 PC-QUANL Program을 사용하여 분석하였다. 연구결과, 병원간호사의 직장 내 괴롭힘에 대한 태도 양상은 세 가지 유형으로 분류되었고, 이들 유형에 의해 설명된 전체 변량은 41.7%였다. 제 1유형은 ‘지지적 극복형’, 제 2유형은 ‘비관적 위축형’, 제 3유형은 ‘유연한 적응형’으로 확인되었다. 결론적으로 병원 내 간호 인력의 역량 강화와 직무의 효율을 높이고 의료서비스의 질적 향상을 위해서는 병원간호사의 직장 내 괴롭힘에 대한 각 유형별 중재전략을 수립하고 적용할 필요가 있다. This study is an exploratory study to identify attitude styles of hospital nurses" workplace bullying and to explain the characteristics of each type. In this study, 47 hospital nurses working at two tertiary hospitals in Seoul and Chungcheongbuk-do were selected through convenience sampling as P samples and 38 Q samples were forcibly distributed on 9 point scale. The collected data were analyzed using the PC-QUANL program. The results emerged that attitude on hospital nurse" workplace bullying was classified into three types, and the total variance explained by these types was 41.7%. The first type was identified as "supportive coping type", the second type as "timid shrink type", and the third type as "flexible adaptation type". In conclusion, it is necessary to establish and apply each type of intervention strategy for hospital nurses" workplace bullying in order to enhance the capacity of the nursing staff in the hospital, to improve the efficiency of the job and to improve the quality of the medical service.

아토피 피부염에서 강화 삼산 온천수 보조치료의 효과 및 안전성에 대한 연구

신지연 ( Ji Yeoun Shin ),홍규락 ( Kyu Rak Hong ),권륭 ( Ryung Kwon ),김예슬 ( Ye Seul Kim ),이설희 ( Sul Hee Lee ),박영립 ( Young Lip Park ),이상훈 ( Sang Hoon Lee ) 대한피부과학회 2019 대한피부과학회지 Vol.57 No.10

Background: Atopic dermatitis is a chronic inflammatory disease associated with long-term use of topical and systemic medications. Several articles have described the use of balneotherapy as an adjuvant treatment for atopic dermatitis in many countries, including Korea. Objective: The goal of this study was to investigate the therapeutic efficacy and safety of balneotherapy as an adjuvant treatment of atopic dermatitis. Methods: Ten patients with atopic dermatitis were enrolled in this study and each patient served as their own control. Testing was conducted on the anterior cubital fossa of the arm. A priori binary randomization was completed to determine which arm would receive balneotherapy or tap water. Patients visited clinics 3 times per week for 2 weeks and had a forearm bath for 15 minutes. Assessment was performed at baseline, and after 1 and 2 weeks of treatment. Results: At the last visit, the balneotherapy group showed improvements in their local eczema area, severity index score, and the degree transepidermal water loss. The physician’s global assessment, patient’s self-global assessment, and skin hydration was increased in both groups. Conclusion: Our study suggests that balneotherapy is a safe adjuvant therapy that could be considered for the treatment of atopic dermatitis. However, more studies are required to demonstrate scientific basis for this treatment. (Korean J Dermatol 2019;57(10):594∼599)

스티븐스 존슨 증후군 및 독성표피괴사융해증 88예의 임상적 고찰

홍정연 ( Jeong Yeon Hong ),정의현 ( Euy Hyun Chung ),양나경 ( Na Gyeong Yang ),김재윤 ( Jae Yun Kim ),허남훈 ( Nam Hun Heo ),이설희 ( Sul Hee Lee ),김정은 ( Jung Eun Kim ),이성열 ( Sung Yul Lee ) 대한피부과학회 2021 대한피부과학회지 Vol.59 No.8

Background: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are potentially fatal acute hypersensitivity reactions that involve the skin and mucous membranes. Because they are relatively rare diseases, it is difficult to obtain well-organized epidemiological data. The clinicodemographic characteristics, culprit drugs, and factors related to disease prognosis may vary. Objective: To identify the characteristics of SJS/TEN by investigating patient clinicopathological characteristics, laboratory findings, suspected drugs, and mortality through a retrospective study using medical record data. Methods: The clinical records of patients diagnosed with SJS/TEN between February 2009 and February 2019 at three medical institutions of Soonchunhyang University were retrospectively reviewed. Data pertaining to sex, age, history, suspected drugs, latent period, laboratory findings, and mortality were collected, and their correlations were analyzed. Results: We identified SJS/TEN in 88 patients. Among the probable causative agents, antibiotics were the most common (29 cases, 33.0%), followed by nonsteroidal anti-inflammatory drugs (NSAIDs) in 20 cases (22.7%). The period between drug administration and symptom onset varied with the causative agent. Patients who died had high SCORTEN scores. In addition, hypertension, diabetes, renal failure, and cardiac disease had a statistically significant association with high SCORTEN. Conclusion: Antibiotics, NSAIDs, antiepileptics and allopurinol were the most commonly implicated drugs in our retrospective study. There was a significant correlation between comorbidities. Because SJS/TEN is a life-threatening condition, early recognition of the suspected drug are important. The results of this study may provide insights that aid in the early diagnosis and prediction of disease outcomes of SJS/TEN in the Korean population. (Korean J Dermatol 2021;59(8):604∼610)