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      • SCOPUSKCI등재

        전투경찰대원에서의 B 형 간염 (肝炎) 표면항원 (表面抗原) 및 항체의 발현빈도에 관한 조사

        이강훈(Kang Hoon Lee),장웅서(Wung Seo Jang),노광해(Kwang Hai Rho),이권준(Gwon Jun Lee),조민구(Min Koo Cho) 대한소화기학회 1983 대한소화기학회지 Vol.15 No.2

        N/A The positive rate of HBsAg and anti-HBs in the sera of 2013 Combat Policemen was surveyed by reverse passive hemagglutination method. The positive rates of HBsAg and anti-HBs related to the duration of service, the areas of previous and present residence and the age were analyzed to figure out if they could influence the positive rates. The results are summarized as follows: 1. Among 2013 Combat Policemen, 182(9.04%) were positive for HBsAg and 390(19.37%) were positive for anti-HBs. 2. HBsAg was found positive in 7. 38% of 664 first grade servicemen, 8. 67% of 369 second grade servicemen and 10.31% of 980 third grade servicemen. Significant low positive rate of HBsAg in the first grade servicemen in comparison to the third grade servicemen was found (p(0.05). Anti-HBs was found positive in 17.17% of 664 first grade servicemen, 18.43% of 369 second grade servicemen and 21. 22% of 980 third grade servicemen. There was also statistical difference between the first grade servicemen and the third grade servicemen (p <0.05). 3. Significant low positive rate of HBsAg in Combat Policemen who had lived in urban area(7. 28%) in comparison to those who had lived in rural area(10.26%) was found(p<0. 025). However no significant difference on previous residential area was observed in the positive rate of anti-HBs. 4. No significant difference on the age at donation and staying area were observed in the positive rate of HBsAg and anti-HBs. We observed that positive rate of HBsAg in Combat Policemen was higher than general populations and positive rates of HBsAg and anti-HBs were higher as the duration of service increased longer. So we should consider active countermeasures for the prevention of hepatitis B infection in Combat Policemen.

      • KCI등재후보
      • SCOPUSKCI등재

        각종 간질환자에서 혈청 Beta2-microglobulin 치의 임상적 의의

        이권준,조민구,최종호,김소연,장석원,조태봉 대한핵의학회 1985 핵의학 분자영상 Vol.19 No.2

        To evaluate the significance of serum beta₂-microglobulin in patients with various liver diseases, serurn Beta₂ m levels were measured in 44 cases of normal controls, 32 cases of asymptomatie HBsAg carriers and 134 patients with various liver diseases, by radioimmunoassay using Phadebas Beta2~micro test kits. The following results were obtained: I) The mean level of serum β₂ m was 1 39+-0.25㎎/ℓ(Mean+-S.D.) in normal controls (1.39+-0.23㎎/ℓ in 24males, 1.38+-0,27㎎/ℓin 20 fernales). 2) The seram levels of B2m in patients with various Iiver diseaaes and asymptomatic HBsAg carriers were as follows; 1.400.27㎎/ℓ in asymptomatic HBsAg carriers, 2.42+-0.377 mg/l in 45 patients with acute viral hepaitis, 2.10+-0.26 mg/l in 46 patients with chronic persistent hepatitis, 2.60+-0.34㎎/ℓin 23 patients with chronic active hepatitis, and 2.60+-0.49 ㎎/ℓin 20 patients with liver cirrhosis. Serum β₂ m levels of each disease group were significantly higher than that of normal controls(p$lt;0.001). 3) There was significant correlation between the levels of serum β₂ m and the degrees of lymphocytic infiltration in patients with chronic active hepatitis(p$lt;0.001). 4) Significant correlations were observed between the levels of serum betA₂,-microglobuin and serum alanine aminotransferase(r=0.68, p$lt;0.05) and bilirubin(r=0.63, p$lt;0.05) in 15 patients with acute viral hepatitis. In conclusion, the serum beta₂,-microglobulin levels were increased in patients with various liver diseases, and it may serve as a new index of liver disease activity.

      • SCOPUSKCI등재

        심근 기능 측정에 사용된 게이트 심근 관류 SPECT 방법의 재현성 평가 : 201Tl과 99mTc-MIBI 게이트 SPECT의 비교 Comparison with Thallium-201 and Technetium-99m-MIBI

        김성은,최원식,이우형,홍의수,현인영,서정기,김대혁,권준,박금수 대한핵의학회 2000 핵의학 분자영상 Vol.34 No.5

        Purpose: We compared the reproducibility of 201Tl and 99mTc-sestamibi (MIBI) gated SPECT measurement of myocardial function using the Germano algorithm. Materials and Methods: Gated SPECT acquisition was repeated in the same position in 30 patients who received 201Tl and in 26 who received 99mTc-MIBI. The quantification of end-diastolic volume (EDV), end-systolic volume (ESV), and ejection fraction (EF) on 201Tl and 99mTc-MIBI gated SPECT was processed independently using Cedars quantitative gated SPECT software. The reproducibility of the assessment of myocardial function on 201Tl gated SPECT was compared with that of 99mTc-MIBI gated SPECT. Results: Correlation between the two measurements for volumes and EF was excellent by the repeated gated SPECT studies of 201Tl (r=0.928 to 0.986; p<0.05) and 99mTc-MIBI (r=0.979 to 0.997; p<0.05). However, Bland Altman analysis revealed the 95% limits of agreement (2 SD) for volumes and EF were tighter by repeated 99mTc-MIBI gated SPECT (EDV: 14.1 ml, ESV: 9.4 ml and EF: 5.5%) than by repeated 201Tl gated SPECT (EDV: 24.1 ml, ESV: 18.6 ml and EF: 10.3%). The root mean square (RMS) values of the coefficient of variation (CV) for volumes and EFs were smaller by repeated 99mTc-MIBI gated SPECT (EDV: 2.1 ml, ESV: 2.7 ml and EF: 2.3%) than by repeated 201Tl gated SPECT (EDV: 3.2 ml, ESV: 3.5 ml and EF: 5.2%). Conclusion: 99mTc-MIBI provides more reproducible volumes and EF than 201Tl on repeated acquisition gated SPECT. 99mTc-MIBI gated SPECT is the preferable method for the clinical monitoring of myocardial function.

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