자세 안정성 개선을 위한 체성감각 자극 시스템 개발

유미(Mi Yu),은혜인(Hye-In Eun),박용군(Yong-Jun Piao),김동욱(Dong-Wook Kim),권대규(Tae-Kyu Kwon),김남균(Nam-Gyun Kim) 제어로봇시스템학회 2007 제어·로봇·시스템학회 논문지 Vol.13 No.9

안구와 손의 협응과제에서 방해물의 Global Effect

이아름 ( Ah Reum Lee ),유미 ( Mi Yu ),은혜인 ( Hye In Eun ),김동욱 ( Dong Wook Kim ),권대규 ( Tae Kyu Kwon ),김남균 ( Nan Gyun Kim ) 전북대학교 공학연구원 (구 전북대학교 공업기술연구소) 2006 工學硏究 Vol.37 No.-

The global effect paradigm intended for eye movements has been investigated for spatial eye-hand coordination through a series of experiments performed with and without a distracter for single task conditions and dual-task condition. Saccades typically land on an intermediate position between a target and a distracter. This so-called global effect or spatial averaging is attributed to incomplete target selection. Our experiment showed that the global effect exists also for hand movements. Since the global effect was mostly similar between eye and hand movements, both movements are coupled for target selections. However, the global effect was different for eye and hand under some conditions. These results explain synchronized time and position at which eye and hand land on a target object. As hand movements are typically accompanied by simultaneous eye movements in everyday life, this coordination enables optimal interactions with surroundings.

나노기둥구조 크기가 섬유아세포의 증식 및 alpha-smooth muscle actin (α-SMA)의 발현에 미치는 영향

강은혜(Eun Hye Kang),이상수(Sang Soo Lee),윤영식(Young Sik Yun),이원재(Won Jai Lee),여종석(Jong Souk Yeo),노태석(Tai Suk Roh),윤인식(In Sik Yun) 대한두개저학회 2020 대한두개저학회지 Vol.15 No.2

Backgound : With advances in medicine and materials engineering, biomaterials, such as silicone and titanium are used in many tissue regeneration cases. Many studies are being conducted to confirm the reactivity of cells to various biomaterials. Among these studies, fibroblast proliferation and differentiation are known as important factors related to capsulation. In this study, we attempted to determine how various sized polyurethane acrylate (PUA) nanopillar structures act on fibroblast proliferation and differentiation. Methods : The scaffolds were prepared in four groups: flat and nanopillar (350 nm, 500 nm, 1,000 nm). Flat group was used as a control. To evaluate the effect of scaffolds of nanopillar structures on fibroblasts, quantitatively analyzed for the degree of adhesion, proliferation and alpha-smooth muscle actin (α-SMA) expression of cells. Results : As a result of the MTT assay, the proliferation was lower than that of the flat group in the nanopillar group. As a result of staining, the intensity of F-actin was significantly different from that of the flat group. And the intensity of α-SMA was different from that of the flat group but not significantly. Conclusions : The nanopillar structure of PUA material seems to play a role in inhibiting the proliferation and differentiation of fibroblasts regardless of the size of the structure. This suggests that the use of PUA nanopillar implants may be effective in suppressing fibrosis due to fibroblast proliferation and differentiation.

인두종괴감 및 연하장에 환자의 식도기능검사

김태일(Tae Il Kim),박효진(Hyo Jin Park),김범수(Pum Soo Kim),박인서(In Suh Park),김충배(Choong Bai Kim),유형식(Hyung Sik Yoo),전우택(Woo Taek Jeon),하은혜(Eun Hye Ha) 대한내과학회 1995 대한내과학회지 Vol.49 No.6

N/A Objectives: The globus sensation and dysphagia are common symptoms originated from esophagus in the absence of organic lesions, Although the exact mechanism of these symptoms remains unknown, it is believed to be related to multiple etiopathogenesis. However, many of the results are controversial. So in this study, the relationship of esophageal motility disorder, gastroesophageal reflux and psychic disturbances were evaluated in patients with globus sensation or dysphagia. Methods: In 66 patients with globus sense and 23 patients with dysphagia, esophagogastroduodenoscopy, esophageal manometry, 24-hour esophageal pH monitoring and psychiatric evaluation(M.M.P.I.) were done. Results: 1) In patients with globus sense, forty seven among sixty six patients(71.2%) demonstrated motility abnormalities in esophageal manometry. Among the abnormalities, the most frequent finding was a nonspecific esophageal motility disorder(31.8%). 24- hour pH monitoring showed abnormal acid reflux in 5/35(14.3%) of patients. Hiatal hernia[12/43 (27.9%)] was the most common finding in esophagogastroduodenoscopy, and reflux esophagitis[9/43 (20.9%)] was the second most. When combining the results of endoscopy findings and 24-hour pH monitoring data, some signs of gastroesophageal reflux were demonstrated in 11/54(20.496) of patients. Psychiatric evaluation(M.M.P.I) was done in seven patients, and the patients showed hypochondriasis, a nxiety and depression tendency. 2) In patients with dysphagia, twenty one among twenty three patients(91,3%) showed motility abnormalities in esophageal manometry. Among the abnormalities, the most frequent finding was a non- specific esophageal motility disorder(39.1%), 24-hour pH monitoring showed abnormal acid reflux in 1/7 (14.3%) of patients. Reflux esophagitis[6/17 (35.3Yo)] was the most common finding in esophagogastroduodenoscopy, and hiatal hernia[3/17 (17.6%)] was the next. When combining the results of endoscopy findings and 24-hour pH monitoring data, some signs of gastroesophageal reflux were demonstrated in 6/17(35.3%) of patients, Psychiatric evaluation (M.M.P.I.) was done in five patients, and the patients showed hypochondriasis, depression and introver sion tendency. Conclusion: From the results obtained, it can be suggested that globus sensation and dysphagia have multiple etiologies. Abnormal esophageal motility findings were commonly found. Psychic disturbances may play a role in its etiopathogenesis. Therefore, esophagogastroduodenoscopy, esophageal manometry, 24-hour pH monitoring and, if needed, psychiatric evaluation should be included in evaluating globus sense or dysphagia. Furthermore, the treatment should be directed toward abnormal results of these evaluation.

황토의 식이 내 첨가에 의한 돼지의 생리적 특성과 등급판정에 미치는 영향

오홍근,최용식,오영열,박상훈,이학용,문대인,한주희,신은혜,이봉근,박영미,강양규,김옥진,박광현,채수완,Oh, Hong-Geun,Chol, Yong-Sik,Oh, Young-Youl,Park, Sang-Hoon,Lee, Hak-Yong,Moon, Dae-In,Han, Ju-Hee,Shin, Eun-Hye,Lee, Bong-Gun,Park, Young-Mi,Ga 한국유기농업학회 2014 韓國有機農業學會誌 Vol.22 No.2

본 연구의 목적은 황토의 식이 첨가에 의한 돼지의 성장 특성과 혈중 조성물의 변화를 규명하는 것이다. 총 153마리의 돼지(1주령 자돈 60마리 및 성돈 93마리)를 공시하였다. 자돈군은 일반사료 식이군, 0.5% 황토 + 일반사료 식이군, 1% 황토 + 일반사료 식이군으로 무작위로 3군으로 재배치하였다. 각 군간 증체량을 비교하였을 때 1% 황토가 포함된 사료를 식이한 군에서 일반사료와 0.5% 황토 + 일반사료 투여군에 비해 체중 증가가 관찰되었으나 통계적으로 유의하지는 않았다. 혈액학적 분석을 실시한 결과, 총 백혈구 수, 총 적혈구 수, 헤모글로빈 수, 혈액 중 혈구용적율, 평균 세포용적율, 평균 세포 내 헤모글로빈량, 평균 세포 내 헤모글로빈 농도, 평균 적혈구 폭, 혈소판 수치 등에서 각 군간의 유의한 차이가 없음을 확인하였다. 성돈군은 일반사료 식이군과 1% 황토 + 일반사료 식이군으로 구분하였으며, 혈청학적 분석에서 혈청 알부민의 농도는 1% 황토 + 일반사료 투여군에서 다른 군에 비하여 유의하게 증가하여 있는 것을 확인하였으나(p<0.01), 다른 지표들에서는 유의한 차이를 발견할 수 없었다. 황토가 포함된 사료를 투여한 군에서 획득한 분변의 조지방 함량은 다른 군에 비하여 유의하게 감소하는 것을 확인하였으며(p<0.001), 조단백 함량 및 조회분 함량은 유의한 차이를 보이지 않았다. 도체의 무게와 등지방 두께의 측정 결과 각 군간의 유의한 차이는 발견할 수 없었으나, 도체의 등급 판정 결과 황토를 투여한 군의 도체 등급은 비투여군에 비해 유의하게 등급이 향상된 것을 확인하였다. 이러한 결과는 황토의 식이 첨가는 돼지의 영양소 흡수를 개선시킴으로서 도체의 등급을 향상시키는 것을 확인하였다. This study was conducted to examined the effect of dietary supplementation of yellow loess on the growth performance and blood component profiles in pigs. A total of one hundred fifty three pigs (60 one weeks old piglets and 93 adult pigs). Piglets were randomly divided into 3 groups which were control, control + 0.5% yellow loess, control + 1% yellow loess. We measured body weight and weight gain among treatment group. Indeed, we obtained hematological data with WBC, RBC, Hb, Hct, MCV, MCH, MCHC, RDW, and PLT in all loess supplemented group compared to the control. Adults were divided into 2 group (control and control + 1% yellow loess) and serum albumin levels in 1% yellow loess supplemented group was significantly higher than the control group (p<0.01). Amount of crude fat in feces was significantly reduced in yellow loess supplemented group (p<0.001), but no differences were observed at crude protein and crude ash in both groups. In carcass weight and back fat thickness, no significant differences were observed between control and yellow loess supplemented groups. The carcass grade was improved by the dietary supplementation of yellow loess compared to the pig fed control. As a results, dietary yellow loess improves nutrient absorption and carcass grade.

아프리카산 발톱개구리 이자의 초기발생과정에서 Sox9 억제가 Pdx1 발현에 미치는 영향

박병용(Byung Yong Park),이여광(Li Guang Li),최은혜(Eun-Hye Choi),정몽룡(Mong-Yong Jung),권기탁(Ki-Tak Kwon),정연호(Yeon-Ho Jeong),김종연(Jong-Youn Kim),김인식(In-Shik Kim),박병건(Byung Keon Park),이영훈(Young-Hoon Lee) 대한해부학회 2007 Anatomy & Cell Biology Vol.40 No.1

이자는 외분비샘과 내분비샘으로 구성되어 있고 신체의 항상성을 조절하는 기관이다. 발생과정 중에 이자는 앞창자 (foregut)의 등쪽과 배쪽에서 융기하여 형성되고 성장하여 하나의 기관으로 유합된다. 발생하는 이자에서 발현되는 초기 유전자의 역할을 확인하는 것은 기관의 형성과 분화를 이해하는데 매우 중요하다. 이자발생에 관여하는 유전자 중에서 Pdx1은 초기에 발현되고 이자발생에 중요하게 관여하는 것으로 알려져 있다. Sox 단백질은 다양한 발생과정을 조절하는 전사인자이고 그중 하나인 Sox9는 발생중인 이자에서 발현되지만 아직까지 그 역할은 잘 알려져 있지 않다. 본 연구에서는 Sox9의 hormone inducible inhibitory mutant를 이용하여 Sox9의 작용을 차단한 결과, 발생하는 아프리카산 발톱개구리의 이자싹(pancreatic bud)에서 Pdx1의 발현이 감소되는 것을 확인하였다. 이상의 결과로 Sox9는 아프리카산 발톱개구리 이자의 발생에 관여할 것으로 생각된다. The pancreas is a mixed exocrine and endocrine gland involved in the control of many homeostatic functions. During embryogenesis, the pancreas arises from dorsal and ventral evaginations of the foregut, which ubsequently fuse into a single organ. The characterization of early genes expressed in the developing pancreas is critical to understand its specification and differentiation. Pdx1 is one of the earliest markers of pancreatic development and a key molecule in its development. Sox proteins form a large class of transcriptional regulators implicated in the control of a variety of developmental processes. One member of this family, Sox9, is expressed in the developing pancreas, but little is known about the function of Sox9 in the developing pancreas. We further investigated Sox9 function during pancreatic development in Xenopus. Using a hormone-inducible inhibitory mutant of Sox9, we found that Pdx1 expression was reduced in the ventral pancreatic buds in Sox9-depleted embryos. We suggest that Sox9 gene expression may be involved in pancreatic development in Xenopus.

노인의 4고(苦)가 자살생각에 미치는 영향

장은혜(Eun Hye Jang),남석인(Seok In Nam) 한국노인복지학회 2015 노인복지연구 Vol.0 No.69

본 연구는 만 65세 이상 노인을 대상으로 하여 노인의 빈곤, 질병, 무위, 고독이 자살생각에 미치는 영향과 우울의 매개효과를 검증하고자 하였다. 이를 위해 2014년 10월 17일부터 11월 24일까지 서울시내 8개의 노인종합복지관에서 317부의 설문지를 수거하였으며, 303부를 최종분석에 활용하였다. 연구가설 검증을 위해 선형회귀분석과 구조방정식을 활용하였으며, 매개효과 검증을 위한 붓스트래핑을 실시하였다. 연구결과, 조사대상자의 약 44%가 자살생각을 해본 것으로 나타났다. 또한 빈곤, 질병, 무위, 고독은 우울을 매개하여 노인의 자살생각에 영향을 주었으며, 무위가 가장 큰 영향력이 있는 것으로 분석되었다. 이러한 연구결과를 바탕으로 노인의 자살예방 및 심리사회적 적응을 위한 실천 및 정책적 개입방안을 제시하였다. This study examined the mediating effect of depression in the relationship among the four major difficulties(i.e., poverty, illness, inactivity, and loneliness) and suicidal ideation among the elderly population aged 65 or over. The data used in this study was collected as part of the“Aging Anxiety and Psychosocial Adaptation of Elderly Population” project which was carried out by the School of Social Welfare in Yonsei University along with the‘Vibrant future research center’ in the Seoul Elder Welfare Center. Totally 317 cases were collected, and 303 responses were used for final analysis. Linear regression analysis, structural equation analysis, and procedures were conducted to verify the hypotheses of this study. The results of the study is as follow; First, 44% of participants responded that they had thought about committing suicide. And among the four major difficulties, inactivity had the strongest effect on suicidal ideation. Moreover, poverty, disease, inactivity, and loneliness showed indirect effects through the mediation of depression as well. Based on the results this study suggested theoretical and practical implications for early prevention of elderly suicide with major four problems and depression.

소음지도 모델링을 위한 계산시간 비교 연구

장은혜(Eun-Hye Jang),박상규(Sang-Kyu Park),박인선(In-Sun Park) 한국소음진동공학회 2009 한국소음진동공학회 학술대회논문집 Vol.2009 No.11

차세대 자동인식 기술을 활용한 유해성분 탐지 서비스 시스템 개발

고은혜 ( Eun-hye Ko ),박수진 ( Su-jin Park ),박인영 ( In-young Park ),이재이 ( Jae-yi Lee ),박경모 ( Kyeongmo Park ) 한국정보처리학회 2017 한국정보처리학회 학술대회논문집 Vol.24 No.2

최근 국내 제품 성분의 안전과 관련된 사건들이 발생하여 국민들 사이에 많은 불안감을 불러일으켰다. 안전 정보의 분산과 용어의 어려움으로 쉽게 유해성을 확인하기 힘든 실정이다. 본 논문에서는 실시간 데이터베이스와 데이터 바인딩 기술을 이용한 유해성분 탐지 서비스 시스템의 연구 개발을 보고한다. 개발 시스템은 이미지 및 바코드를 통해 정보 검색하기 쉽고 빠르게 유해성분을 탐지하여 빠른 속도로 출력할 수 있다.

지능형 원격검침 서버시스템 개발

임은혜(Eun-Hye Im),이상염(Sang-youm Lee),박병석(Byung-seok Park),최인지(In-Ji Choi) 대한전자공학회 2010 대한전자공학회 학술대회 Vol.2010 No.10