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비침습적 맥파 측정을 위한 압력센서 패키징에 관한 연구
김은근(Eun-Geun Kim),남기창(Ki Chang Nam),허현(Hyun Heo),허영(Young Huh) 대한전기학회 2009 대한전기학회 학술대회 논문집 Vol.2009 No.7
In this paper, we have proposed and demonstrated a tonometry sensor array for measuring arterial pulse pressure. A sensor module consists of 7 piezoresistive pressure sensor array. Wire-bonded connection was provided between silicon chip and lead frame. PDMS(poly-dimethylsiloxane) was coated on the sensor array to protect fragile sensor while faithfully transmitting the pressure of radial artery to the sensor. Tonometric pulse pressure can be measured by this packaged sensor array that provides the pressure value versus the output voltage.
김은근(Eun-Geun Kim),허현(Hyun Heo),남기창(Ki-Chang Nam),허영(Young Huh) 대한전기학회 2008 대한전기학회 학술대회 논문집 Vol.2008 No.10
한의학에서 손목의 맥파를 손으로 짚어 보고 파형의 변화로써 병면의 원인을 파악하는 것은 기본적은 진단 방법이다. 진단을 위해 요골동맥의 촌, 관, 척 세 부위의 맥파를 수지를 일정 가입을 하며 맥의 깊이 , 강약, 빠르기 등을 촉진을 통해 맥상을 분석한다. 본 연구에서는 촌, 관, 척 부위를 동시 측정하기 위해 각 부위에 5개의 압력센서 어레이가 적용된 15채널 맥진기를 구성하였다. 또한 요골 동맥 부위에 적정 가압을 유지하기 위해 공기 커프를 이용한 공압 가압 방식을 적용하였다. 본 가압 방식을 통해 요골 동맥 부위에 연속적이며 정밀 가압제어가 가능하였다.
Baermann Funnel법의 선충 분리 여과지 선발
강헌일,은근,하지혜,이재현,김동근,김용철,최인수,Kang, Heonil,Eun, Geun,Ha, Jihye,Lee, Jaehyun,Kim, Donggeun,Kim, Yongchul,Choi, Insoo 한국응용곤충학회 2016 한국응용곤충학회지 Vol.55 No.4
Baermann funnel법을 이용하여 비교적 선명한 선충 분리를 위해서는 Kimwipes 4매 정도를 여과지로 사용하여야 한다. 더욱 효율적이고 경제적인 선충 분리용 여과지를 찾기 위하여 시판되고 있는 15개의 제품을 Kimwipes와 비교 실험을 진행하였다. 선충 분리 효율 검정에는 Heterodera sp.의 유충, Meloidogyne sp.의 유충, Pratylenchus sp., Rhabditis sp., Acrobeloides sp., Panagrolaimus sp., Poikilolaimus sp. 그리고 Diplogasterida 등 8속의 선충을 이용하였다. 전체 선충 분리 효율은 42.0 - 88.8%로 나타났다. 1회 비용, 선충 분리 효율 그리고 선명도를 고려하였을 때, 선명도는 A이고 분리 효율은 69.4%로 Kimwipes 4장과 비슷하며(P=0.05), 비용은 50% 저렴한 국내 업체 모나리자 사의 Pulling Kitchen Towel 1매 사용이 가장 적합하였다. The Baermann funnel method requires approximately four Kimwipe tissues for research a nematode count under a stereo microscope. To select more efficient and economical nematode extraction paper for nematode extraction, 15 different kinds of tissue papers were tested and compared with Kimwipe tissues. Nematode species used in the extraction efficiency tests include juvenile (J2) of Heterodera sp., J2 of Meloidogyne sp., Pratylenchus sp., Rhabditis sp., Acrobeloides sp., Panagrolaimus sp., Poikilolaimus sp. and Diplogasterida. The extraction efficiency varied between 42.0 to 88.8%. Considering costs, extraction efficacy, and clarity, the Pulling Kitchen Towel (Monalisa Co., Korea) is the best tissue, with clarity A, isolation efficiency of 69.4% (not significantly different compared to Kimwipe 1 ply 88.8%), and 1/2 costs per isolation of Kimwipe 2 ply.
초음파 응답특성 분석에 의한 위장 경화 진단시스템의 설계
임도형,김은근,이균정,박원필,김한성,신태민,최서형,이용흠,Lim, Do-Hyung,Kim, Eun-Geun,Lee, Gyoun-Jung,Park, Won-Pil,Kim, Han-Sung,Shin, Tae-Min,Choi, Seo-Hyung,Lee, Yong-Heum 대한의용생체공학회 2007 의공학회지 Vol.28 No.2
Functional gastrointestinal disorders affect millions of people of all age regardless of race and sex. There are, however, rare diagnostic methods for the functional gastrointestinal disorders because functional disorders show no evidence of organic and physical causes. Our research group identified recently that the gastrointestinal tract well in the patients with the functional gastrointestinal disorders becomes more rigid than healthy people when palpating the abdominal regions overlaying the gastrointestinal tract. The aim is, therefore, to develop a diagnostic method for the functional gastrointestinal disorders based on quantitative measurement of the rigidity of the gastrointestinal tract well using ultrasound technique. For this purpose, a preliminary ultrasound diagnostic system was developed and verified through phantom tests. The system consisted of transmitter, ultrasonic transducer, receiver, TGC, and CPLD, and verified via a phantom test. For the phantom test, ten soft-tissue specimens were harvested from porcine. Five of them were then treated chemically to mimic a rigid condition of gastrointestinal tract well, which was induced by functional gastrointestinal disorders. Additionally, the specimens were tested mechanically to identify if the mimic was reasonable. The customized ultrasound system was finally verified through application to human subjects with/without functional gastrointestinal disorders(Normal and Patient Groups). It was identified from the mechanical test that the chemically treated specimens were more rigid than normalspecimen. This finding was favorably compared with the result obtained from the phantom test. The phantom test also showed that ultrasound system well described the specimen geometric characteristics and detected an alteration in the specimens. The maximum amplitude of the ultrasonic reflective signal in the rigid specimens $(0.2{\pm}0.1Vp-p)$ at the interface between the fat and muscle layers was explicitly higher than that in the normal specimens $(0.1{\pm}0.0Vp-p)$ (p<0.05). Clinical tests using our customized ultrasound system for human subject showed that the maximum amplitudes of the ultrasonic reflective signals nea. to the gastrointestinal tract well for the patient group$(2.6{\pm}0.3Vp-p)$ were generally higher than those in normal group$(0.1{\pm}0.2Vp-p)$ (p<0.05). These results suggest that newly designed diagnostic system based on ultrasound technique may diagnose enough the functional gastrointestinal disorders.
Sn-4.0wt%Ag-0.5wt%Cu 솔더 접합계면의 강도특성과 미세파괴거동에 대한 In-situ관찰
이경근,최은근,추용호,김진수,이병수,안행근,Lee, Kyung-Keun,Choi, Eun-Geun,Chu, Yong-Ho,Kim, Jin-Soo,Lee, Byung-Soo,Ahn, Haeng-Keun 한국재료학회 2008 한국재료학회지 Vol.18 No.1
The micro-structural changes, strength characteristics, and micro-fractural behaviors at the joint interface between a Sn-4.0wt%Ag-0.5wt%Cu solder ball and UBM treated by isothermal aging are reported. From the reflow process for the joint interface, a small amount of intermetallic compound was formed. With an increase in the isothermal aging time, the type and amount of the intermetallic compound changed. The interface without an isothermal treatment showed a ductile fracture. However, with an increase in the aging time, a brittle fracture occurred on the interface due mainly to the increase in the size of the intermetallic compounds and voids. As a result, a drastic degradation in the shear strength was observed. From a microshear test by a scanning electron microscope, the generation of micro-cracks was initiated from the voids at the joint interface. They propagated along the same interface, resulting in coalescence with neighboring cracks into larger cracks. With an increase in the aging time, the generation of the micro-structural cracks was enhanced and the degree of propagation also accelerated.
-침술효과 객관화를 위한 연구- 접지와 절연조건이 경락전위에 미치는 영향
이용흠,이균정,김은근,김한성,신태민,Lee, Yong-Heum,Lee, Qyoun-Jung,Kim, Eun-Geun,Kim, Han-Sung,Shin, Tae-Min 한국정보통신학회 2006 한국정보통신학회논문지 Vol.10 No.12
When a patient is positioned at insulated bed and practitioner is positioned at insulated floor, that condition could be a cause of lessening effect in acupuncture practice. We investigated how Ground connection and Insulation could influence on the electrical meridian potential between practitioner and patient during acupuncture practice. We treated 30 normal healthy subjects with acupuncture and measured changes in the electrical potential between the stomach meridian points ST-39 and ST-37 in response to light touch after insertion of a needle at ST-36. At first, we stimulated non-insulated needle and measured electrical potentials for non ground, patient ground only, practitioner ground only, all ground respectively. Then we used insulated needles and measured same as above. Non-insulated all ground subject elicited positive mean potential $44.6{\pm}19.2{\mu}V$ and showed $181.4{\pm}59.7{\mu}V$ peak to peak potential. Practitioner ground only showed negative mean potential of $51.5{\pm}9.3{\mu}V$ and $367.4{\pm}27.8{\mu}V$ of peak to peak potential. Patient ground only revealed no mean potential of $2.9{\pm}1.3{\mu}V$, $16.4{\pm}11.9{\mu}V$ of peak to peak potential. All ground showed no mean potential of $1.6{\pm}0.7{\mu}V$, $3.3{\pm}1.9{\mu}V$ of peak to peak potential. In case of Insulated condition, there elicited no mean potential. Non ground and Practitioner only showed weak value of peak to peak potential as $7.8{\pm}2.6{\mu}V$ and $8.4{\pm}2.5{\mu}V$ each. But patient only and all ground showed no potential as $4.7{\pm}2.2{\mu}V$, $3.4{\pm}2.2{\mu}V$, respectively. Therefore, Ground connection modulate the energy transfer course between practitioner and patient. Insulation block energy transfer but static electrical impulse between practitioner and patient.
토노메트리 맥파 측정 압력 센서의 재현성 및 반복성 평가
남기창(Ki Chang Nam),김은근(Eun Geun Kim),허현(Hyun Heo),허영(Young Huh) 대한전기학회 2009 정보 및 제어 심포지엄 논문집 Vol.2009 No.10
본 논문에서는 기존 개발된 압력센서 어레이에 대하여 위에서 언급한 맥파 측정 센서의 조건에 부합하는지에 대한 성능 평가를 수행하였다. 가압 및 맥압의 동시 측정을 위하여 Piezoresistive 압력센서를 사용하였고, 맥폭을 측정할 수 있도록 어레이 형태로 구성하였다. 맥장의 측정은 촌, 관, 척을 측정을 통하여 가능하다. 사랑의 맥과 동일한 파형을 재생해주는 맥파 재현 장치를 이용하여 재현성 평가에 활용하였다. 진폭과 주기에 대한 반복성 및 재현성 평가 결과 Operator 간의 실험에서는 반복성 및 재현성이 10% 이하로 양호한 결과가 나왔다. 하지만 센서간 재현성에서 진폭의 경우 20%~30% 사이의 값으로 측정 능력 보통의 결과가 나왔다. 이것은 상하 이동 엑츄에이터에 센서를 위치시키는데 있어서 미세한 차이가 생겼거나 센서를 코팅하기 위한 PDMS의 미세한 두께차이 등으로 인한 패키징된 센서마다의 특징인 것으로 보인다.