자궁적출술 후 정맥 내 자가통증조절 시 저용량의 Naloxone 이 술 후 진통효과와 부작용에 미치는 영향

윤희동 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.41 No.6

수술후 통증관리를 위한 Buprenorphine의 지속적 경막외 투여효과

윤희동(Hee Dong Yoon),박영철(Young Chul Park),임혜 대한통증학회 1996 The Korean Journal of Pain Vol.9 No.1

N/A Background: Buprenorphine, a new synthetic thebaine derivative, is a partial agonist of the opioid p-receptor with high receptor affinity, great lipid solubility, and slow rate of opiate receptor association and dissociation. Continuous epidural infusion of opioid can pos- sibly produced undesirable effects, such as respiratory depression, pruritus, etc, in spite of effective postoperative analgesia. Methods: The present study was undertaken to compare the analgesic properties and sid effects of continuous epidural infusion of buprenorphine combined with bupivacaine, and morphine combined with bupivacaine in 90 patients following elective gynecologic lower abdominal surgery. At the end of surgery, the initial bolus doses were 3 mg mor- phine(M group), O.l5mg buprenorphine(0.15B group), 0.3 mg buprenorphine(0.3B group) com- bined with 0.125% bupivacaine 10ml, and subsequent continuous infusion doses were 6mg morphine plus 0.125% bupivacaine 100ml(M group) and 0.6mg buprenorphine plus 0.125% bupivacaine 100 ml(0.15B, 0.3B group during 48 hours. The assessment of analgesic efficacy and side effects were made at arrival of recovery room, 1 hr, 4 hr, 8 hr, 24 hr, 36 hr, and 48 hr after the epidural injection. Results: The pain score during 48 hours was significantly higher in the 0.15B group than in the M group and 0.3B group(P<0.05), and the number of patients requiring additional analgesics was significantly higher in the 0.15B group than in the M group and 0.3B group (P<0.05). Signs of respiratory depression were not noted, and the incidence of pruritus, nausea, and vomiting was slightly lower in the 0.15B group and 0.3B group than in the M group, and the incidence of sedation and urinary retention was similar in three group. The subjective rating of satisfaction was better in the 0.3B group than in the M group and 0.15B group(P<0.05). Conclusion: The above results suggest that continuous epidural infusion of bupre- norphine combined with low-dose bupivacaine is an advisable method of postoperative an- algesia.

Sage를 이용한 선형대수학 개념의 시각화

이상구,정혜인,윤희동 한국수학교육학회 2011 수학교육 학술지 Vol.2011 No.2

선형대수학은 대부분의 학생이 추상수학을 처음 접하는 과목이다. 따라서 학생들은 새롭고 다양한 수학적 개념을 마주치면서 적지 않은 어려움을 겪는다. 20세기 컴퓨터의 발전은 수학교육 특히 선형대수학 교육에서 큰 변화의 가능성을 제시하였다. 다양한 수학적 개념을 이해시키는 과정에서 도구를 이용하는 시각적 접근방법은 학생들이 수학적 개념을 쉽고 직관적으로 이해하는데 큰 도움이 된다. 본 발표에서는 최근에 각광을 받는 웹상의 공개소프트웨어인 Sage-Math를 이용하여 다양한 선형대수학의 개념을 시각적으로 소개한다. Sage-Math는 인터넷 웹 환경을 기반으로 하는 수학 연산용 도구이다. 이 도구는 2008년 4월에 미국 워싱턴대학을 중심으로 개발되었으며, 현재 그 기능은 Web-Mathematica를 능가하는 강력한 기능을 가지며, 많은 고가의 상업용 소프트웨어들을 별도로 설치하지 않고도, 인터넷 웹 브라우저로 접속하여 언제 어디서나 무료로 사용할 수 있도록 구성되어 있다. 여기서는 선형대수학에서의 예로 interactive한 벡터의 합과 차, 일차결합, 생성, 다양한 선형변환에 대하여 개발된 알고리즘과 구현된 결과물을 제시한다. 이에 보태어 Sage를 이용한 흥미 있는 수학적 모델링을 공개한다.

Rocuronium 과 Lidocaine 의 전투여가 Succinycholine 투여 후 나타나는 생화학적 변화와 속상수축 및 근육통에 미치는 영향

김재환,장문석,윤희동,박영철 대한마취과학회 2001 Korean Journal of Anesthesiology Vol.40 No.5

Background: The purpose of this study was to assess the changes in serum potassium and creatine kinase concentrations and the incidence of fasciculations and myalgia when rocuronium and lidocaine were used in combination and separately as pretreatment before succinylcholine. Methods: We studied 60 patients undergoing a minor elective surgery, in a prospective double blinded method. Three groups each with 20 patients were pretreated before a 1.5 mg/kg succinylcholine administration with 0.05 mg/kg rocuronium three min before (group R), 1.5 mg/kg lidocaine 30 sec before (group L), or both rocuronium and lidocaine (group RL). Serum potassium and creatine kinase were respectively measured 5 min after succinylcholine administration and 24 h after the operation. Fasiculations and myalgia on postoperative day 1 and day 2 were evaluated. Results: The increase in creatine kinase and incidence of myalgia on postoperative day 1 was less in the RL group than in the R group and L group. The incidence of fasiculations was higher in the L group than in the R group and RL group. There was no increase in serum potassium in any group. Conclusions: The combined use of rocuronium and lidocaine was more effective in reducing creatine kinase and postoperative myaliga than when they were used separately. However, the fasciculations were only reduced by the use of rocuronium.

고리원전의 온배수 방출이 주변 해조군집에 미치는 영향

김영환,안중관,윤희동,장민아,Kim, Young-Hwan,Ahn, Jung-Kwan,Yoon, Hee-Dong,Jang, Min-A 한국조류학회(藻類) 2007 ALGAE Vol.22 No.4

This study is intended to clarify the effects of heated effluents on intertidal benthic marine algal community in Korea. The species composition and biomass of marine algae at the discharge canal of Gori nuclear power plant on the southeastern coast of Korea were investigated seasonally from February 2001 to October 2006. As a result, 54 species (7 blue-green, 12 green, 9 brown and 26 red algae) of marine algae were found at the discharge canal during the past six years. In general, the number of species observed was abundant during winter to spring and less in autumn. Enteromorpha compressa, E. intestinalis, E. prolifera and Caulacanthus ustulatus were common species found more than 80% frequency during the study period. Seasonal fluctuations of mean biomass were 1-440 g dry wt m?2 and dominant species in biomass were Enteromorpha spp. (contribution to a total biomass proportion 28%), Sargassum horneri (14%) and Amphiroa beauvoisii (14%). It is evident from the floristic composition and biomass data that unique micro-environment of the discharge canal support different communities from those on the intake or control area. Results from the large numbers of surveys before and during plant operation showed that, in the regions influenced by thermal effluents such as the discharge canal of power plants, the process of ecological succession has been proceeded. It is assumed that the uni-directional water flow and the time of overhaul largely affect the development and succession of benthic marine algal communities of the discharge canal.

Enflurane이 Diltiazem을 전처치한 흰쥐의 적출심장의 좌심실기능에 미치는 영향

윤석민,임상호,윤희동,박영철 대한마취과학회 1998 Korean Journal of Anesthesiology Vol.35 No.6

Background : Calcium channel blockers and volatile anesthetics have depressant effects on cardiac function. Both of them appear to exert, qualitatively and quantitatively, different effects on myocardial contractility, coronary flow, and myocardial oxygen balance. The aim of this study was to examine the direct cardiac effects of the enflurane in the presence of diltiazem. Methods : Isolated Sprague-Dawley rat hearts (N=45) were perfused at constant pressure with oxygenated Modified-Krebs solution (pH 7.4, 37oC). Isovolumetric left ventricular pressure (LVP) and dP/dt were measured via a latex balloon and transducer. Also, coronary flow and oxygen tensions at the coronary inflow and outflow were measured. After stabilization period, all hearts were subjected to the application with diltiazem (100 ng/ml). Thereafter, they were subdivided into three groups; group 1, 2, 3. Groups subjected to the combination of diltiazem (100 ng/ml) with enflurane 1.1, 2.2, or 3.3 vol%, respectively. Results : After the application of diltiazem, myocardial contractility and heart rate were significantly decreased, and coronary flow were significantly increased. The combination of diltiazem with enflurane depressed myocardial contractility, heart rate, myocardial O2 consumption, and percentage of O2 extraction more than diltiazem alone, and their effects were dependent on the concentration of enflurane. However, there was no difference in the change of coronary flow and oxygen delivery between diltiazem and the combination of diltiazem with enflurane. Conclusions : These in vitro findings demonstrate that the combination of diltiazem with enflurane shows greater direct negative inotropic and negative chronotropic effect, and is associated with less attenuation of coronary autoregulation, but with a larger reduction in O2 utilization. The present results suggest that high enflurane anesthesia in the diltiazem-pretreated patients could result in profound cardiac depression. (Korean J Anesthesiol 1998; 35: 1035∼1046)

북평공장 #1 Cement Mill Separator 개조

편우식,남양현,윤희동 한국시멘트협회 2005 시멘트 심포지움 Vol.32 No.-

노인환자에서 질식 자궁절제술중 발생한 심한 저혈압의 증례 보고

조헌,장성호,임혜자,공명훈,윤희동,김난숙 대한마취과학회 1994 Korean Journal of Anesthesiology Vol.27 No.12

An anesthesiologist should keep in mind the various risk factors during anesthetic man- agement of geriatric patients. Unlike young patients, elderly patients may manifest more than one pathophysiologic process associsted with progressive degenerative changes in various organs. The successful anesthetic management requires detailed information about the cause and severity of the underlying disease, thorough understanding of geriatric specific hemodynamic particularities, and more careful monitoring by experienced personnel. We experienced a case of profound hypotension during general anesthesia for vaginal hysterectomy in a 67 year-old female patient. Anesthesia was induced with thiopental-vecuronium and was maintained with nitrous oxide, oxygen and enflurane. One hundred and five minutes after the induction, profound hypotension and bradycardia with S-T segment depression developed without specific events and were corrected by vigorous therapeutic managements. She discharged from the hospital on 7th postoperative day without complications.

Succinylcholine 투여 후 나타나는 생화학적 변화, 속상수축, 근육통을 예방하기에 적절한 Rocuronium 전투여의 시간간격

김성배,김재환,김운영,장문석,윤희동,박영철 대한마취과학회 2002 Korean Journal of Anesthesiology Vol.42 No.5

실시간 임베디드 UAV 시스템을 위한 딥러닝 기반 물체 검출기 최적화

박정빈(Jeongbin Park),박승일(Seungil Park),김찬영(Chanyoung Kim),서재규(Jae Kyu Suhr) 대한전자공학회 2021 대한전자공학회 학술대회 Vol.2021 No.11