순위 비교를 기반으로 하는 다양한 유전자 개수로 이루어진 암 분류 결정 규칙의 생성

윤영미,변상재,박상현,Yoon, Young-Mi,Bien, Sang-Jay,Park, Sang-Hyun 한국정보처리학회 2008 정보처리학회논문지D Vol.15 No.6

마이크로어레이 기술은 최근 실험적 분자생물학 분야에서 활발히 사용되고 있는 기술이다. 마이크로어레이 데이터는 한 번의 실험으로 수 만개의 유전자에 대한 발현값을 얻을 수 있으므로, 여러 질병의 발현형질을 연구하는데 매우 유용하게 사용된다. 마이크로어레이 데이터의 문제점은 참여하는 유전자의 수에 비해 참여하는 샘플(생물조직샘플)의 수가 매우 적고, 분류분석 기법을 사용하여 얻어진 분류자의 해석이 어렵다는 점이다. 본 연구에서는 위의 문제점을 해결하고자, 샘플 내 순위를 이용하여 동일한 생물학적 목적으로 수행된 공개 마이크로어레이 데이터를 통합하고, 순위 비교를 기반으로 하는 다양한 유전자 개수로 이루어진 암 분류 결정 규칙들로 이루어진 분류자를 제안한다. 본 분류자는 k개의 규칙으로 이루어진 앙상블 방법을 기반으로 하며, 하나의 규칙은 최대N개의 유전자, 관련유전자간의 순위비교 관계식, 판별클래스로 이루어져 있다. 하나의 규칙에 참여하는 유전자의 수를 다양하게 함으로써 좀더 신뢰성 높은 분류자를 생성할 수 있다. 또한 본 분류자는 생물학적 해석이용이하며, 분류자를 구성하는 유전자를 명확히 식별할 수 있고, 총 개수가 많지 않으므로 임상환경에서의 사용가능성도 생각해 볼 수 있다. Microarray technology is extensively being used in experimental molecular biology field. Microarray experiments generate quantitative expression measurements for thousands of genes simultaneously, which is useful for the phenotype classification of many diseases. One of the two major problems in microarray data classification is that the number of genes exceeds the number of tissue samples. The other problem is that current methods generate classifiers that are accurate but difficult to interpret. Our paper addresses these two problems. We performed a direct integration of individual microarrays with same biological objectives by transforming an expression value into a rank value within a sample and generated rank-comparison decision rules with variable number of genes for cancer classification. Our classifier is an ensemble method which has k top scoring decision rules. Each rule contains a number of genes, a relationship among involved genes, and a class label. Current classifiers which are also ensemble methods consist of k top scoring decision rules. However these classifiers fix the number of genes in each rule as a pair or a triple. In this paper we generalized the number of genes involved in each rule. The number of genes in each rule is in the range of 2 to N respectively. Generalizing the number of genes increases the robustness and the reliability of the classifier for the class prediction of an independent sample. Also our classifier is readily interpretable, accurate with small number of genes, and shed a possibility of the use in a clinical setting.

청소년의 생의 의미에 영향을 미치는 요인

윤영미,조헌하,Yoon, Young-Mi,Cho, Hun-Ha 한국아동간호학회 2011 Child Health Nursing Research Vol.22 No.4

Purpose: The purpose of this study was to analyze factors affecting meaning of life in adolescents. Methods: Data were collected from April 5 to June 20, 2010. The participants for this study were 343 Korean middle and high school students, recruited from four middle and high schools located in Seoul. Data collection was conducted through the use of 7 questionnaires. The data were analyzed with the SPSS WIN 12.0 program using descriptive statistics, ANOVA, Pearson correlation coefficients and stepwise multiple regression. Results: 1) The mean total item score for the meaning of life scales was 2.99, which was slightly high. 2) There was a significant relationship between meaning of life and self-esteem, self control, parenting attitude, family satisfaction, school adjustment, and career maturity. 3) Stepwise multiple regression analysis showed that self-esteem, family satisfaction, school adjustment, parenting attitude and career maturity were predictors of meaning of life and accounted for 57.1% of the variance in meaning of life. Conclusion: Self-esteem, family satisfaction, school adjustment, parenting attitude and career maturity were variables influencing meaning of life in adolescents. These results indicate a need to develop nursing interventions to increase self-esteem, family satisfaction, school adjustment, parenting attitude and career maturity in order to improve meaning of life for adolescents.

대학생의 안전의식과 안전생활 실천행위 및 대학 안전관리 서비스 체계에 대한 인식

윤영미(Young-Mi Yoon),성경숙(Kyung-Suk Sung),김은주(Eun-Joo Kim) 한국생활환경학회 2014 한국생활환경학회지 Vol.21 No.6

The purpose of this study was to investigate safety consciousness(SC), safety practicing Behavior(SPB) and perception about safety management service system of university campus(PSMSS) among university students. A descriptive study was conducted. The participants were 855 university students. Data was collected self-administered questionnaires that modified by the investigator. The data was analyzed by the SPSS win 20.0 program using descriptive statistics, Chi-square test, Pearson correlation coefficients, ANOVA. In survey, The mean of total item score the SC was 3.53±.37 and SPB was 3.52±.58, which was slightly high and PSMSS was 2.73±.74, which was slightly low. There was a significant correlation between SC, SPB and PSMSS among university students(r=-.38 ~.41). The respondents’ score of SC, SPB and PSMSS were significant differences in sex, major and volunteer work experience commonly. Therefore it is necessary to develop nursing intervention to coordinate the level of related factors in order to prevent accidents. These results suggest that safety education programs are necessary to achieve safety for university students and to prevent accidents.

초 · 중 · 고등학생의 집단따돌림 경향분석

윤영미(Yoon, Young Mi) 한국보건간호학회 2007 韓國保健看護學會誌 Vol.21 No.2

채팅 데이터의 기분 분류 시스템

윤영미(Young-Mi Yoon),이영호(Young-Ho Lee) 한국컴퓨터정보학회 2009 韓國컴퓨터情報學會論文誌 Vol.14 No.5

온라인 커뮤니케이션 중 인터넷 메신저를 이용한 대화의 비중이 점점 증가하는 추세이나, 이러한 메신저 대화정보를 효율적으로 재사용할 수 있는 어플리케이션은 많지 않다. 메신저 대화 정보는 사용자의 언어 습관이 반영된다는 특성을 가진다. 이러한 언어 습관은 자주 쓰이는 단어나 이모티콘으로 나타나며, 이들로써 사용자의 기분을 잘 파악할 수 있다는 특성이 있다. 그러므로 본 연구에서는 자주 쓰이는 단어들이나, 기호 등을 이용해서 효과적으로 대화 내용 작성자의 기분 등을 분류할 수 있는 기법을 제안한다. 이러한 기법은 충분한 반복 실험을 통해서 95% 이상의 높은 정확성으로 기분을 분류할 수 있음을 보여주고 있다. It's a trend that the proportion of using an internet messenger among on-line communication methods is getting increased. However, there are not many applications which efficiently utilize these messenger communication data. Messenger communication data have specific characteristics that reflect the user's linguistic habits. The linguistic habits are revealed through frequently used words and emoticons, and user's emotions can be grasped by these. This paper proposes the method that efficiently classifies the emotions of a messenger user using frequently used words or symbols. The emotion classifier from repeated experiments achieves high accuracy of more than 95%.

QFD를 이용한 고객 중심적 관광 웹 사이트 설계

윤영미 ( Young Mi Yoon ),김식 ( Sik Kim ) 한국항공경영학회 2005 한국항공경영학회지 Vol.3 No.1

가천길대학의 코압교육시스템에 관한 연구

윤영미(Young-mi Yoon),이병문(Byung-mun Lee) 한국정보기술학회 2004 한국정보기술학회논문지 Vol.2 No.2

Co-Op program is an educational system which significantly improves the Quality of career-oriented education by integrating a college curriculum with industrial work skills. Under this system, students are required to actually work full time at a real company for four to six months, performing an actual task and experiencing cultural aspects of industry. Consequently, they acquire valuable industrial working knowledge and know-how which would never be obtained at their school alone. In Korea, Gacheongil college has been operating a Co-Op system as a specialized program since the year 2002. Co-Op program is regarded as ''Work-Integrated Learning, and very? actively pursued by universities and colleges in Canada, U.S.A., HongKong, Australia, Netherlands, and Great Britain, to name a few. In this article, as a new education model, an introduction of the Co-op program operated at Gacheongil college, including its motivations, objectives, on-going projects, and outcomes, is given.

성인남성의 금연동기 영향요인

윤영미(Yoon, Young Mi),양은경(Yang, Eun Kyung),신성례(Shin, Sung Rae) 한국성인간호학회 2012 성인간호학회지 Vol.24 No.5

비영양적 빨기습관으로 인한 부정교합의 치험례

윤영미 ( Young Mi Yoon ),이상호 ( Sang Ho Lee ),이난영 ( Nan Young Lee ),김진수 ( Jin Soo Kim ) 조선대학교 치의학연구원 2009 Oral Biology Research (Oral Biol Res) Vol.33 No.3

미술치료를 통한 조현병 청년의 정체성에 대한 내러티브 탐구

윤영미(Yoon, Young-Mi),전순영(Chun, Soon-Young) 한국미술치료학회 2021 美術治療硏究 Vol.28 No.6

본 연구는 조현병 청년이 미술치료를 통해 경험한 삶에서 정체성을 중심으로 깊이 있게 살펴봄으로써, 참여자가 무엇을 경험하며 어떤 의미를 주는지 탐구하는데 그 목적이 있다. 그 과정에서 나타난 조현병 청년의 경험과 의미를 내러티브 방법으로 탐구하고자 하였다. 연구대상은 발병한지 6년 이상으로 조현병을 진단받은 27세 청년이다. 연구 기간은 2020년 7월부터 9월까지이며, 일주일에 2번 90~120분씩 총 20회기에 걸쳐 미술치료를 실시하였다. 재구성된 경험 이야기는 조현병 청년 자신의 정체성을 찾기 위한 큰 시간적 흐름에 따라 ‘관심 종자 같은 느낌’, ‘조현병과 우연한 조우’, ‘과거로의 여행’, ‘삶의 의미 있는 선택’로 구성되어 있다. 이를 바탕으로 조현병 청년의 미술치료를 통해서 자신의 정체성을 찾기 위한 경험의 의미는 ‘치유관계에서 편안하고 안전한 관계로 전환’, ‘사랑과 고뇌를 작품으로 승화’, ‘작품 속에서 나의 삶을 이해’, ‘미래로 향하는 길에서 꿈과 희망’이다. 이상의 결과를 통해서 볼 때 인생에서 가장 중요한 청년의 시기에 조현병으로 인한 불안과 두려움 속에서도 미술치료는 자기이해와 자기수용의 자기 재구성(self reconstruction)으로 성장의 기회가 되었고, 자신의 삶을 주체적으로 살아갈 수 있도록 도움을 주었다. 이러한 연구 결과를 바탕으로 본 연구의 의의와 제한점에 대하여 논의 하였다. The subject was a 27-year-old male diagnosed with schizophrenia more than 6 years ago. The subject is on medication after in-patient treatment in a closed psychiatric ward in city A. Twice-weekly art therapy sessions were conducted from July 2020 to September 2020 for a total of 20 sessions of 90 to 120 minutes each. “Feeling Like Being an Attention Seeker,” “a Chance Encounter with Schizophrenia,” “A Trip to the Past,” and “A Meaningful Choice in Life” were the parts of the subject’s reconstructed life story as he strove to find his identity over time. Through art therapy, several themes were identified to give meaning to his experiences of finding his own identity. These themes included “Transition from a Therapist-Patient Relationship to a Comfortable and Safe Relationship,” “Transforming Love and Anguish into Work,” “Understanding my Life in the Work,” and “Dream and Hope Met on the Road to the Future.” For the subject, art therapy became an opportunity for growth through self-reconstruction, which consists of self-understanding and self-acceptance despite his medical condition, which generates anxiety and fear during an important period in his life. Art therapy has also helped the subject to live an independent life. Based on these results, the implications and limitations of this study are discussed.