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동의보감(東醫寶鑑) 중(中) 평위산연계방(平胃散連繫方)의 활용(活用)에 대한 고찰(考察)
유진덕,이학재,김영일,이용숙,조대연,박종찬,윤용갑,Liu Chin-The,Lee Hak-Jae,Kim Young-Il,Lee Young-Sook,Cho Dae-Yeon,Park Jong-Chan,Yun Yong-Gab 대한한의학방제학회 2004 大韓韓醫學方劑學會誌 Vol.12 No.1
The following are the conclusions obtained by the philological study of the prescriptions introduced in Dongeuybogam such as Pyungwuisan, Pyungwuisan-added prescriptions, Pyungwuisan blended prescriptions: 1. Pyungwuisan and drugs based on Pyungwuisan were prescribed for stomach diseases, food poisoning, indigestion, impaired spleen, symptoms developed by dampness, diseases caused by changing water, diarrhea, edema, malignant malaria, an intestinal convulsion, blood in excrement, malaria, abortion, sparrow eye. 2. Dual prescriptions using Pyungwuisan and other independent prescriptions were applied to internal diseases concerning digestion, diarrhea and dysentery, abscess, intestinal swelling jaundice, symptoms developed by dampness, malaria, vomit, etc. 3. Etiological factors and diseases for which Pyungwuisan and medicines based on Pyungwuisan, dual prescriptions using Pyungwuisan were prescribed, were surveyed to include indigestion, weak spleen and stomach, drying dampness of spleen and stomach, dysfunctioning gall bladder, infection, damaged internals, external sensitiveness and internal damage, hypochondria, chilliness due to lack of chi. 4. A prescription for each disease needed specially added medicines to Pyungwuisan as the following: 1) For indigestion and dyspepsia, Pyungwuisan were prescribed with optional addition of Hoisaengsan, Sagunjatang, Ryukgunjatang, Ijintang, Sosihotang, etc., according to the symptoms, and were most frequently used with aromatic and digestive medicines such as mawwa medivata fermentata, malt, natgrass galingale rhizome, vilous amomum fruit, aucklandia root, round cardamom seed etc. 2) For diseases originated from damage by coldness, Pyungwuisan was taken with suitable amount of Jichulhwan, Hyangsosan, Hyangyusan, according to the symptoms. 3) For diarrhea and dysentery, Pyungwuisan were prescribed with the recipes of Oryeongsan, Sambaektang, Ijintang. 4) For jaundice, prescriptions always included natgrass galingale rhizome in the recipe of Pyungwuisan. 5) For malaria, mostly added prescriptions to Pyungwuisan were Sagunjatang, Ryukgunjatang, Ijintang, with usual addition of antifebrile dichroa root, tsaoko, green tangerine orange peel. 6) Pyungwuisan was prescribed with Hoisaengsan for vomit, with Oryeongsan for edema, and with kinds of Ueolgukhwan for hypochondria.
배풍탕(排風湯) 전탕액(煎湯液)이 XO/HX에 의해 손상(損傷)된 배양(培養) 척수감각신경세포(脊髓感覺神經細胞)에 미치는 효과(效果)
유진덕,윤용갑,Yu Jin-Deok,Yun Yong-Gap 대한한의학방제학회 2000 大韓韓醫學方劑學會誌 Vol.8 No.1
To evaluate the effect of Baepungtang(BPT) water extract on cultured mouse spinal sensory neuron which was inhibited by xanthine oxidase(XO) and hypoxanthine(HX)-induced oxigen radicals, MTT assay, NR assay, Neurofilament enzymeimmuno assay and LDH activity assay were carried out after the cultured mouse spinal sensory neuron were preincubated with various concentrations of BPT water extract for 3 hours prior to exposure of XO/HX. The results obtained were as follows: 1. XO/HX, a oxigen radical, decreased the survival rate of the cultured mouse spinal sensory neuron cell on NR assay and MTT assay. 2. $MTT_{50}$ value and $NR_{50}$ value of XO/HX were 30 mU/ml XO/O.2 mM HX. 3. BPT water extract have efficacy of increasing neurofilament. 4. BPT water extract have efficacy of increasing LDH activity. From above the results, It is concluded that BPT has marked efficacy as a treatment for the damages caused in the XO/HX-mediated oxidative process.
동의보감(東醫寶鑑) 중(中) 천화분(天花粉)이 주약(主藥)으로 배오(配伍)된 방제(方劑)의 활용(活用)에 대한 고찰(考察)
서창우,유진덕,Seo Chang-Woo,Liu Chen-Duk 대한한의학방제학회 2003 大韓韓醫學方劑學會誌 Vol.11 No.1
Through the research into the date of Radix Thichosanthis main blended 21 kinds of prescriptions Radix Thichosanthis from Donguibogam. This study summrized as follows; The suitable dosage of Radix Thichosanthis per one application is one to two don(about $4{\sim}8g$). Radix Thichosanthis Radix main blended prescriptions broadly use in the symptoms of diabetes, excessive thirst, cabuncles and eye diseases In diabetes and excessive thirst, the structes of Radix Thichosanthis main blended prescriptions are commonly used Seng Mak San(生脈散), Radix Puerariae(葛根), Frectus Schisandrae(五味子), Radix Ophiopogonis(麥門冬) In Furuncles, Carbuncles and Cancer like diseases, the structes of Radix Thichosanthis main blended prescriptions are generally used Kumeunhwasan(金銀花散), Jipaesan(芷貝散), Twonongsan(透膿散).
스쿠버다이빙 초보자의 부력조절기 사용에 따른 공기사용량과 실패횟수 분석
장경호(Kyung Ho Chang),유진상(Jin Sang Yoo),오문엽(Moon Yeop Oh),설정덕(Jeong Dug Sul) 한국사회체육학회 2011 한국사회체육학회지 Vol.0 No.46
This is an experimental research to verify a buoyancy compensator`s rolls for a beginner of scuba-diving. Subjects of this study is 66 adults who are participated in the summer camp for the Leisure Sports Events of 2010 Summer(Leports 2010). the 33 subjects are involved in the comp arative group, while the other 33 subjects are in the experimental group. The volume of air consuming was measured at the point of decent, underwater swimming, and ascent to the surface of water. Results of the study indicates as following: Firstly, the non-using buoyancy group uses more air at the point of decent to compare that of the using buoyancy group, that indicates more probabilities of diving related injuries such as sinus squeeze, carotid sinus reflex, breathing resistance, or barotrauma of ear can be developed. Secondly, the non-using buoyancy group uses less air during the underwater swimming from the point of decent to the point of ascent. However, there are many chance of unwished ascent with the non-using buoyancy group. Thirdly, the relationship with a partial correlation between the number of mistake and the submerging at the decent area was significant, that indicates more chances of accidents may happen at the beginning of diving for the novice diver. Discussions regarding that the instructor should teach and request using a buoyancy compensator to the beginner to prevent unexpected accidents are provided.
Mitochondrial Malate Dehydrogenase 활성을 이용한 냉장우육과 냉동우육의 판별법 개발
한규호(Kyu-Ho Han),김남규(Nam-Kyu Kim),이시경(Si-Kyung Lee),조진국(Jin-Kook Cho),최강덕(Kang-Duk Choi),전유진(You-Jin Jeon),이치호(Chi-Ho Lee) 한국식품영양과학회 2005 한국식품영양과학회지 Vol.34 No.10
본 연구는 냉장우육과 냉동우육의 판별법을 개발하기 위하여, 한우 육을 부위별(사태, 등심, 우둔, 양지)로 구입하고 냉장(4±1℃), 냉동(-4, -18, -77℃)상태로 15일 저장하면서 압착육즙채취기를 이용하여 근육 세포내 mitochondria 막에 존재하는 mitochondrial malate dehydrogenase 활성 특성을 비교 연구한 결과 다음과 같은 결과를 얻었다. 본 실험을 위하여 제작된 압착육즙채취기를 이용하여 정량적인 압착 육즙을 얻을 수 있었고, 1.5 g의 우육을 이용하였을 때 0.15 mL의 압착육즙을 얻었다. 냉장우육과 냉동우육 간의 mitochondral malate dehydrogenase의 각 부위별 활성은 사태의 경우 냉장우육은 23.63 Unit/mL의 활성을 나타내었고, -4℃는 20.91 Unit/mL, -18℃는 26.43 Unit/mL 그리고 -77℃는 25.90 Unit/mL의 활성을 나타내었다. 동일한 부위에서 저장온도에 따른 효소의 활성도는 냉장우육보다 -4℃를 제외한 냉동 저장 온도(-18, -77℃)에서 모두 유의적으로 높은 효소의 활성을 나타내었다(p<0.05). 동일한 저장 온도에서 각 부위 간에 활성의 차이점은 -77℃에서 냉동 저장한 우육이 유의적 차이 없이 가장 높은 효소 활성을 나타내었고, -77℃ 저장온도를 제외하고는 모두 유의성 있는 변화량을 나타내었다(p<0.05). 실험군의 압착육즙 내 mitochondrial malate dehydrogenase의 활성은 10분간 흡광도 변화량을 조사함으로써 계산되었다. 등심을 제외한 모든 부위에서 효소반응개시 3분 후에 -4℃에서 동결우육을 제외하고 동결우육의 효소 활성이 떨어지는 것을 확인할 수 있었고, 5분 반응 후에는 그 효소의 활성을 발견할 수 없었다. 냉장우육은 12분까지 활성을 측정할 수 있었다. 15일간 냉장우육 및 냉동우육을 저장 온도에 따라 저장하면서 그 활성을 측정하였는데, 저장 기간이 길어져도 그 효소 활성의 차이는 유의적으로 변화하지 않고, 모든 실험군(사태, 등심, 양지, 우둔 부위)에서 유의적으로 유사한 활성을 유지하였다(p<0.05). 따라서 본 연구결과로부터 mitochondrial malate dehydrogenase의 활성을 이용하여 냉장우육과 냉동우육 유무를 판별하는데 유효한 지표로 사용 가능한 것으로 사료되었다. The object of this study is to develop the method for differentiating fresh meat from frozen meat by using the measurement of the mitochondrial malate dehydrogenase in the Korean native cattle. The principle of this experiment is based on the fact that the enzyme proteins associated with mitochondria membrane could be released by freezing. The methods of differentiating fresh meat from thawed, frozen meat were studied by measurements of mitochondrial malate dehydrogenase activity of meat press juice. Fresh and frozen beef were stored at 4, -4, -18 and -77℃ for 15-day storage period. A meat press machine using air pressure was manufactured especially for these experiments, and sufficient amount of drip (about 0.15 mL/g) from 1.5 g of beef sample was efficiently obtained under a pressure of 8 kg/cm2 generated by the meat pressing machine. The mitochondrial malate dehydrogenase activities of frozen meat drip juices stored at -18 and -77℃ were significantly higher than those of fresh and frozen meat samples at -4℃ (p <0.05) during 10-min reaction period. However, the enzyme activities of the frozen meat drip juices (-18 and -77℃) disappeared after 5 minutes of the reaction, which was not observed from the fresh and -4℃ frozen meats. The enzyme activity maintained until 12 minutes for the fresh and -4℃ frozen meats. From these results, the mitochondrial malate dehydrogenase could be considered as an indicator to differentiate fresh beef from frozen one.