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유용균(Yong Gyun Yoo),김재욱(Jae Wook Kim),김세광(Sei Kwang Kim),김영한(Young Han Kim),연정은(Jung Eun Yeon),손용석(Yong Seok Sohn),정영내(Young Nae Jung),이윤정(Yun Jung Lee) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.3
The etiology of neural tube defects, a category encompassing spina bifida, anencephaly and encephalocele, remains highly controversial and unclear, However, there is overwhelming evidence supporting a multifactorial etiology for this group of defects. Recent studies have shown that folic acid supplements taken periconceptionally can reduce a woman's risk of having a child with a neural tube defect. Qenetic screening could identify women who will require folic acid supplements periconceptionally to reduce their risk of having a child with a neural tube defects. Recently, we encountered two cases of recurrent anencephaly that had occurted in a same pregnant woman in our hospital. We report these two cases with brief review of the literatures.
유용균(Yong Gyun Yoo),조재성(Jae Sung Cho),박용원(Yong Won Park),한성식(Sung Shik Han),이연혜(Yeon Hye Lee),윤혜정(Hye Jeong Yoon) 대한산부인과학회 1999 Obstetrics & Gynecology Science Vol.42 No.3
N/A Purpose: The diagnostic usefulness of fetal echocardiography in congenital heart disease is well known. One of the indications for fetal echocardiography is presence of extracardiac anomalies and such coexistent congenital heart disease may have important implications for obstetric and neonatal management. Materials and methods: 496 women with singleton pegnancies with amgenital anomalies that underwent penatal care and follow-up in Severance Hospital for 5 years from 1991 to 1995 were evaluated for the incidence of congenital heart disease. Results: The incidence of congenital heart disease in fetuses with the associated extracardiac anomalies were as follows; central nervous system 6.9%(11/160), gastro-intestinal system 10.7%(8/75), genito-urinary sysem 4.7%(4/85), others 5.6%(4/72). Thirty-one of eighty-ane fetuses with congenital heart disease were found to have the associated extracardidac anomalies and ten of them chenoscenal abnormalities. Conclusion: We recommend that fetuses with congenital extracardiac anomalies sbould be checked for the presence of congenital heart disease and chmmosomal abnormalities, if needed.