http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
김대황,류재욱,우재춘,홍성엽 한국농화학회 1992 Applied Biological Chemistry (Appl Biol Chem) Vol.35 No.4
Buprofezin은 곤충의 틸피저해 살충제로서 인축에 극히 안전하여 세계 50개국에 등록되어 사용되고 있으며 국내에도 수년 전부터 수입되어 크게 호평받고 있는 약제인데 이의 구조가 독특하여 합성에 어려움이 있다. 기존의 합성법은 유독한 포스겐을 사용하는 방법으로써 실험실적으로는 물론 산업적 생산 방법으로써도 용이하지 않은 방법이다. 본 연구에서는 유독한 포스겐의 사용을 피하고 고수율로 buprofezin을 합성하는 새로운 합성법을 개발하였다.
이상호,성낙도,김대황,류재욱,우재춘,구동완 한국농화학회 2000 Applied Biological Chemistry (Appl Biol Chem) Vol.43 No.1
The influence of the 2-(4-(6-chloro-2-benzoxazolyloxy)phenoxy)-N-phenyl- propionamide derivatives on the herbicide activities against rice plant with pre-emergence and post-emergence in down land were examined and the structure activity relationship (SAR) were analyzed by Free-Wilson and Hansch method. In pre-emergence, the SAR approach is shown that the optimal, (π)_(opt)=0.91, hydrophobicity with electron donating effect of the ortho substituted mono substituents and 2,3,4-substituted three substituents were found to be contribute the herbicidal activity. Whereas, in post-emergence, the optimal, (π)_(opt)=0.50, hydrophobicity with electron withdrawing effect of meta substituted mono subsituents and 2,3-substituted two substituents were found to be contribute the herbicide activity. The herbicide activities with post-emergence more increase than that of pre-emergence. It is assumed from the SAR equations that the 2-methyl-3-methoxy-4-cyano group substituent is selected as the most lowest herbicide activity against rice plant with post-emergence in green house. The hydrolysis reaction was proceeded through nucleophilic addition-elimination (Ad._(NU-E)) with the orbital control between LUMO of substrate and HOMO of water molecule. And molecular electrostatic potential (MEP) of none (H) substituent was discussed.