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급성 설사 환자에서 대장내시경 과정 중에 얻은 생검 조직 및 장액을 이용한 원인균의 분석
우가은 ( Ka Eun Woo ),정성애 ( Sung Ae Jung ),조지윤 ( Ji Yoon Cho ),조유경 ( You Kyoung Cho ),송지현 ( Ji Hyun Song ),김도영 ( Doe Young Kim ),유권 ( Kwon Yoo ),문일환 ( Il Hwan Moon ) 대한내과학회 2002 대한내과학회지 Vol.63 No.6
목적: 본 연구의 목적은 급성 설사로 내원하는 환자들을 대상으로 대장내시경을 시행하여 대장 점막 병변을 관찰하고,대장내시경 과정 중에 얻은 생검 조직과 장액으로 배양 검사를 실시하여, 대장내시경의 유용성을 알아보고자 하였다. 대상 및 방법: 2000년 3월부터 8월까지 14일 이내의 수성 또는 혈성 설사를 주소로 내원한 환자 중 염증성 장질환, 방사선성 대장염, 허혈성 대장염 및 위막성 대장염의 과거력이 있거나 현재 임상적으로 의심된 환자를 제외한 41 Background: The aim of this study was to investigate the value of colonoscopy for assessment of colonic mucosal lesions and for microbial identification in patients with acute diarrhea. Methods: From March 2000 to August 2000,forty-one patients with water
수리미 혼합물 제조 시 우유 첨가에 따른 3D 프린팅 적합성에 미치는 영향
강유석(Yoo-Seok Kang),황혜지(Hye-ji Hwang),박예린(Ye-Lin Park),한현수(Hyeon-Su Han),박정철(Jeong-Cheol Park),서훈서(Hun-Seo Seo),최예희(Ye-Hui Choi),김수형(Su-Hyeong Kim),우가은(Ka-Eun Woo),정소미(So-Mi Jeong),이가혜(Ga-Hye lee),안동현( 한국생명과학회 2023 생명과학회지 Vol.33 No.5
본 연구에서는 식품 3D 프린터용 카트리지 소재 개발을 위하여 수리미 제조 시 첨가하는 물과 얼음 대신 우유를 첨가하여 색도, 물성, 관능적 특성을 대조군과 비교하여 실험을 진행하였다. 색도 측정 결과, 우유 첨가량이 증가함에 따라 비 가열 수리미 혼합물과 가열 수리미 혼합물 모두 L*값과 b*값이 대조군에 비해 증가하였고, 40 wt% 비율 첨가 시료에서 가장 높은 값이 나오는 것을 확인하였다. 물성 측정 결과는 비 가열 수리미 혼합물의 경우 우유 첨가량이 증가함에 따라 경도와 부착성이 증가하였고, 40 wt% 비율첨가 시료에서 가장 높은 값이 나오는 것을 확인하였다. 가열 수리미 혼합물의 경우 우유 첨가량이 증가함에 따라 경도, 검성, 부착성, 씹힘성이 증가하고, 탄력성, 응집성, 복원성은 감소하였다. 위의 결과로 우유첨가 비율이 증가할수록 일정한 경향이 나오는 것을 확인하였다. 관능 평가 결과에서는 우유 첨가량이 증가함에 따라 비린내, 맛, 경도가 유의적으로 개선되는 경향을 보였으며, 냄새, 이미, 조직감이 개선되는 것을 확인하였다. 결론적으로 40 wt% 비율의 우유 첨가 시 수리미의 품질 특성을 좌우하는 큰 요소 중 하나인 백색도 개선과 유화물로서의 물성 증진 효과 및 관능적인 증진효과를 얻어 고품질의 3D 프린터용 실꼬리돔 수리미 카트리지 소재를 개발할 수 있다는 것을 확인하였다. Milk is an emulsion, improving texture of surimi mixture and able to suppress off flavors and abnormal tastes. Therefore, this study aimed to identify the effective properties of milk in the preparation of a surimi mixture for 3D printing. The sensory and physical properties of surimi mixtures containing 0%, 20 wt%, and 40 wt% milk were evaluated, where the unheated surimi mixture with added milk demonstrated increased firmness and adhesiveness compared to the negative control group. In addition, the hardness, adhesiveness, gumminess, and chewiness of the mixture containing 40% milk were highest, but springiness, cohesiveness, and resilience were lowest. In the sensory evaluation, as the amount of milk increased, a fishy smell, abnormal taste and texture improved, hardness and preference increased as well. From these results, it was confirmed that a surimi mixture can be prepared with milk to improve its physical and sensory properties for 3D printing when compared to the negative control mixture. In particular, it was revealed that the physical properties and preference of the surimi mixture are best when prepared with 40% milk.
Ticlopidine(Ticlid^�)으로 유발된 담즙울혈성 황달 1예
우가은,조홍근,신길자 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.2
담즙울혈성 황달은 ticlopidine 투여후 발생할 수 있는 부작용중 매우 드문 질환으로, 저자들은 1996년 11월 이화여자대학교 부속병원에 입원한 42세 남자 환자에서 ticlopidine 투여후 발생한 담즙울혈성 황당1예를 경험하였기에 문헌고찰과 더불어 보고하는 바이다. Ticlopidine, a platelet aggregation inhibitor, is widely used in the secondary prevention of stroke and previous manifestation of peripheral arterial occlusive disease, Ticlopidine is also used to prevent myocardial infarction and post-stenting occlusion after intracoronary stent implantation. The exact mechanism of action of ticlopidine is unclear, but likely involves the inhibition of platelet activity by the suppression of adenosine diphosphate-induced patelet aggregation. The most common adverse effects are gastrointestinal problems, skin reactions, and hematologist changes. The adverse hepatic effects are not frequent(4% in different series). We experienced a case of ticlopidine-induced cholastatic jaundice, and report with review of literatures
박기령,조성민,우가은,이기현,손혜영,임정윤,최진혁,이순남,정화순 梨花女子大學校 醫科大學 醫科學硏究所 1997 EMJ (Ewha medical journal) Vol.20 No.2
Chronic neutrophilic leukemia(CNL) is a very rare myeloproliferative disease, characterized by sustained mature neutrophilic leukocytosis with granulocytic bone marrow infiltration, high NAP(neutrophilic alkaline phosphatase) score and absence of philadelphia chromosome, It is frequently accompanied by hepatosplenomegaly, elevated serum vitamin B_12 and uric acid level. For the diagnosis of CNL, the leukemoid reaction, especially secondary to neoplasia, infection and autoimmune diseases, should be excluded. Since Tuohy's first description in 1920, more than 50 cases fullfilling the above criteria have been reported worldwide, and 4 cases in Korea. Several authors have demonstrated the defect of intracellualr killing in the mature neutrophil and this finding correlates well with the very high incidence of fatal infection, The hemorrhagic diasthesis in CNL is caused by functional abnormality of the platelet. This disease has tendency to transform to blastic crisis and acute leukemia as in other myeloproliferative disease, but characteristically shows frequent coexistence with multiple myeloma. Until now , the therapeutic trials in CNL have been disappointing. Hydroxyrea and busulfan can control hyperleukocytosis. On the basis of functional defect in neutrophil, alpha-2b-interferon has been tried and several reports have demonstrated the clinical and functional effect of interferon on CNL. CNL is very rate hematologic disease and there are few report about general aspect of disorder. We report here a typical CNL case presenting with splenomegaly and leukocytosis with a review of the literature.
김영선,조영주,이현경,신미승,신태림,이진화,우가은 대한내과학회 1998 대한내과학회지 Vol.54 No.3
Systemic lupus erythematosus and myasthenia gravis are autoimmune disorders in which genetic, environmental and hormonal as well as immunological factors have been implicated. We experienced a case of 24 year-old female patient developed SLE(anemia, leukopenia, facial malar rash, high titers of anti-DNA and anti-nuclear antibody) 3 years following successful therapeutic thymectomy for myasthenia gravis. A review of the warld-wide literature revealed 8.3% to 24.3% association between myasthenia gravis and SLE However there has been no controlled epidemiological study to prove a real association between them two disease. The differential diagnosis of fatigue and fever in patient with SLE should always include the possibility of myasthenia gravis.