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오혜원,신승원,장형진,안광석,이석근,이의주,고병희,이준희,Oh, Hye-Won,Shin, Seung-Won,Jang, Hyeung-Jin,Ahn, Kwang-Seok,Lee, Seok-Geun,Lee, Eui-Ju,Koh, Byung-Hee,Lee, Jun-Hee 사상체질의학회 2014 사상체질의학회지 Vol.26 No.1
Objectives This paper was aimed to review experimantal and clinical articles on Yeoldahanso-tang(YDHS), figuring out the recent tendency and suggesting the future prospects of YDHS-related studies. Methods The articles published in Korean or English since 2000 were searched, screened, and classified into experimental or clinical studies. And we structured designs, methods and results of the included studies into each table for the experimental studies or the clinical studies. Especially tools to diagnose constitutions and patterns identified in clinical researches were also summarized in the tables. Results 28 articles are finally included. 14 experimental studies are mostly in vitro designs to show efficacy of YDHS. There are only 2 studies for the safety. Among 14 clinical studies, 12 case studies target disorders of central nervous system, viral infection, skin ulcer and so on. 2 studies are before and after studies on cerebral infarction and effects on liver function. Conclusions Based on the efficacy of YDHS on central nervous system, it acquires higher level of evidence such as randomized controlled trials in the future. In addition other diseases such as skin ulcer and so on, it needs to be done more specific experimental or clinical studies so that we can get statistically significant results.
비기허증(脾氣虛證) 환자의 식사 전후 주관적 식욕과 Gut Hormone 혈중 농도에 대한 탐색적 연구
오혜원,이지원,김제신,이준희,Oh, Hye-Won,Lee, Ji-Won,Kim, Je-Sin,Lee, Jun-Hee 사상체질의학회 2015 사상체질의학회지 Vol.27 No.1
Objectives The aim of this study was to investigate clinical factors of SQD syndrome by tracking plasma gut hormone (active ghrelin, active Glucagon-like peptide-1(GLP-1), pancreatic polypeptide(PP), total peptide YY(PYY)) profiling of pre-post prandial standard meal between SQD group and normal group. Methods A total of 24 adult participants were consecutively recruited on April 2014. They were diagnosed as either by SQD syndrome or normal by Spleen Qi Deficiency Questionnaire (SQDQ). On the experimental day, blood samplings of 2 ml were repeatedly collected at 6 points from 2 groups for measuring plasma levels of gut hormones. At every point, subjective appetite sensations were self-registered. Results & Conclusions 1. There were significantly lower subjective 'Appetite' (p=0.012) and higher 'Satiety' (p=0.012) in SQD group. At each time point, subjective 'Appetite' was significantly lower at 60 min after breakfast (p=0.034) and 'Satiety' were significantly higher at 15 min (p=0.020) and 120 min (p=0.044) after breakfast in SQD group. 2. There were no significant differences in plasma levels of gut hormones (active ghrelin, active GLP-1, PP, total PYY) between SQD and normal group. Also at each time point, there were no significant differences of plasma levels of gut hormones between SQD and normal group. 3. Changes in plasma levels of gut hormones compared to baseline were not significantly different at each time point between SQD and normal group. Plasma PYY levels compared to baseline increased in SQD group following 15 min and 30 min after breakfast but decreased in normal group. 4. Further investigation is needed to construct gut hormone profiling and in this perspective, we can approach evaluation tool on variable appetite in Traditional Korean Medicine (TKM) syndrome in the future.
만성 긴장성 두통을 호소하는 소음인(少陰人), 태음인(太陰人) 환자 3례
오혜원,박윤성,이준희,고병희,이의주,Oh, Hye-Won,Pak, Yun-Seong,Lee, Jun-Hee,Koh, Byung-Hee,Lee, Eui-Ju 사상체질의학회 2013 사상체질의학회지 Vol.25 No.4
Objectives We report a series of 3 chronic tension-type headache cases who were constitutionally typed as the Soeum type, Taeeum type and treated with Dangguibaekhaoguanjung-tang, Chungshimyeonja-tang or Chunghyulganggui-tang. Methods In treating 1 patient who was constitutionally typed as the Soeum type, Case 1 fell into the category of the Taeeum symptomatology, 2 patients who were constitutionally typed as the Taeeum type, Case 2 and Case 3 fell into the category of Dry-Heat symptomatology. Each patient was given Sasang medication according to protocol: Dangguibaekhaoguanjung-tang to Case 1, Chungshimyeonja-tang to Case 2, Chunghyulganggui-tang to Case 3. On admission day and approximately 2 weeks later, patients evaluated their pain and quality of life using SF-36 and HIT-6. The patients symptoms were observed daily and NRS scores were recorded daily. Results and Conclusions 2 Patients(Case1, Case2) showed improvement in their NRS scores, SF-36 scores and HIT-6 scores. 1 patient(Case3) showed improvement in NRS scores, but worse SF-36 scores and no improvement in HIT-6 scores. Treating chronic tension-type headache based on Sasang Constitutional therapy was found to be effective for managing pain. The treatment protocol suggested in this investigation should be explored and verified in future studies.
전정-고유감각을 중심으로 한 감각통합치료와 가정프로그램이 자폐스펙트럼장애 아동의 작업수행도, 운동·자세기술, 시운동 통합에 미치는 영향
오혜원(Oh Hye-Won),강보라(Kang Bo-Ra) 대한치료과학회 2021 대한치료과학회지 Vol.13 No.1
Objective: The purpose of this study is to investigate the effects of sensory integration therapy and home program centering on vestibulo-proprioceptive sensory on the occupational performance, motor and posture skills, and visual-motor integration of children with autism spectrum disorders. Method: Ten children with autism spectrum disorder were subjected to sensory integration therapy centered on vestibulo-proprioceptive sensory and a home program. Sensory integration therapy was performed once a week for 8 weeks, 40 minutes each, and the home program was performed 5 times a week, 10 minutes each, for 8 weeks. Children s performance capacity was evaluated using COPM, COMPS-II, and VIM-IV. Results: As a result of COPM evaluation, performance was 3.39±1.15 before intervention and 5.19± 0.91 after intervention(p<.05), and satisfaction was 3.71±0.96 before intervention and 5.39±1.26 after intervention(p<.05). The results of COMPS-Ⅱ were 3.61±2.38 before the intervention and 4.42±3.04 after the intervention. The standard time-motor coordination score of VMI-VI was 55.50±14.95 points before intervention and 64.40±17.04 after intervention(p<.05). Conclusion: Through this study, it was confirmed that sensory integration therapy and home program centered on vestibulo-proprioceptive sensory in children with autism spectrum disorders affect the children s occupational performance, motor and postural skills, and visual-motor integration.
공동주택 바닥 복사냉방 시스템을 위한 제습형 보조냉방기의 대표실 적용 평가
오혜원(Oh Hye-Won),정창호(Jeong Chang-Ho),이진영(Lee Jin-Young),여명석(Yeo Myoung-Souk),김광우(Kim Kwang-Woo) 한국건축친환경설비학회 2010 한국건축친환경설비학회 학술발표대회 논문집 Vol.2010 No.10
In order to apply radiant floor cooling system in a residential building, it is required to install dehumidification/sub-cooling equipment according to the characteristics of cooling load. But it may not be appropriate to install dehumidification/sub-cooling equipment in every room because of cost and system operation efficiency. So it might be considered to install dehumidification/sub-cooling equipment only in the representative room. In this study, therefore, preventing condensation/sub-cooling performance for each room were evaluated through the field experiment in this condition. The results show that preventing condensation/sub-cooling performance for each room is more influenced by door's open/close than distance to the system. In most cases, preventing condensation/sub-cooling performance were satisfied, but it can be concluded that it is better to install dehumidification/sub-cooling unit separately if dehumidification load of a room is expected to be large.
오혜원(Hye-Won Oh),박태형(Tae-Hyoung Park) 한국지능시스템학회 2004 한국지능시스템학회논문지 Vol.14 No.1
인쇄회로기판 제작에 사용되는 국제표준규격의 거버 파일로부터 부품 위치 이름을 자동으로 추출하기 위한 문자인식 시스템을 제안한다. 거버 파일은 벡터형식의 그림파일로서, 각종도형 및 기호가 문자와 혼합되어 있으며, 가로쓰기와 세로쓰기 및 역 세로쓰기가 병용된다. 거버문자인식 시스템은 거버 파일에서 문자패턴을 추출하여 분리하는 전 처리 단계와 추출된 패턴을 인식하는 인식단계 및 인식된 문자와 숫자를 조합하여 부품위치이름을 구성하는 후 처리단계로 구성된다. 특히 인식률 향상을 위하여 신경회로망에 의한 다중인식기 및 구조적 특징을 이용한 검증기를 개발한다. 본 논문에서 개발된 거버문자 인식시스템은 인쇄회로기판 조립 및 검사 장비를 위한 자동 프로그래밍 시스템에 사용되어, 전자제품 제조시스템의 생산성 향상에 기여할 수 있다. We propose the character recognition system for Gerber files. The Gerber file is the vector-formatted drawing file for PCB manufacturing, which includes various symbols, figures and characters. Also, the characters are written in horizontal, vertical, and reverse-vertical directions. In this paper, we newly propose the Gerber-character recognition system to recognize all of component names located in PCB. To improve the performance, we develop the multiple recognizers by neural networks and the verifier considering the structural features. The developed system has been installed to the auto-programming software for PCB assembly and inspection machines.
오혜원 ( Hye Won Oh ),이혜진 ( Hye Jin Lee ),김민호 ( Min Ho Kim ),김동관 ( Dong Kwan Kim ) 대한통합의학회 2013 대한통합의학회지 Vol.1 No.1
Purpose : The purpose of this study was to investigate the effects of music intervention upon lighting on stress. Method : The participants 60 college students, were divided three groups. Two groups were apply each music and bright lighting(bright lighting groups) and music and dark lighting(dark lighting groups) during 13minutes at Snozelen and the other group was control group. Each groups were assessed stress resistance, activity of parasympathetic nerve, activity of sympathetic nerve, balance of ANS, physical arousal by EKG of CANS 3000, at before and after other each intervention. The analyses were performed using version of SPSS 17. Result : The change rate of bright lighting group was showed statistically significant decrease in stress resistance compared to control group. And the change rate of dark lighting group was showed statistically significant decrease in resistance stress, activity of parasympathetic nerve, and balance of ANS compared to control group and statistically significant increase in stress resistance and activity of parasympathetic nerve compared to bright lighting group. Conclusion : The results of this study indicate that music intervention on dark lighting is more effective on decrease of stress than application of bright lighting and general lighting.
다발성 전이를 동반한 후복막강 악성 혈관주위상피모양세포종양
오혜원 ( Hye Won Oh ),김태효 ( Tae Hyo Kim ),차라리 ( Ra Ri Cha ),김나영 ( Na Young Kim ),김현진 ( Hyun Jin Kim ),정운태 ( Woon Tae Jung ),이옥재 ( Ok Jae Lee ),이정희 ( Jeong Hee Lee ) 대한소화기학회 2014 대한소화기학회지 Vol.64 No.5
Perivascular epithelioid cell tumors (PEComas) are unusual mesenchymal neoplasms composed of histologically and immunohistochemically distinct perivascular epithelioid cells (PECs). Although PEComas have the potential to behave in a malignant fashion, malignant PEComas arising from the retroperitoneum are extremely rare. A 68-year-old woman presented with a painful palpable mass in her left upper abdomen. Computed tomography of the abdomen showed a 9 cm sized heterogeneous mass in left para-aortic space and multiple hypervascular nodules in the liver. 18F-fludeoxyglucose-PET/CT showed multifocal hypermetabolic lesions in retroperitoneum, liver, and skeletal bones. Percutaneous needle biopsies were done on the retroperitoneal and hepatic mass. Both specimens were positive for human melanoma black-45 (HMB-45) on histological and immunohistochemical staining which was compatible with PEComas. Herein, we report a rare case of retroperitoneal PEComa with multiple metastases involving liver and bone at initial diagnosis that exhibited aggressive behavior and resulted in a devastating prognosis. (Korean J Gastroenterol 2014,64:302-306)