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오용창,임원준,석욱,주남영,정용학,김명준,우종길,박순규 대한천식알레르기학회 1997 천식 및 알레르기 Vol.17 No.4
Objectives: Allergen is closely related with local features and cultural environment and a new apporach method regarding causes triggering aggravation is especially required due to complex and variety of ordinary residence and pollution of living environment recently. We, therefore, performed this study to inspire the necessity of identification of causative afeuts in aothmatic patiends in pusan area. Methods: We measured serum specific IgE antibody by means of chemiluminescent analyzer employing MAST, classified the level from class 0 to 4 and interpreted the result in order to ideutify allergen on total 262 patients consisted of inpatients and outpatients who had been presumed as extrinisic asthma and treated in this hospital during 2 and a half years from June of 1994 to December of 1996. Results: 1. With regard to sex and age distribution, the rate of men versus women was 1: 1.3, while in the distribution by age, the twenties and the thirties were the most as 29 % and 26% respectively. 2. The result of interpretation of the test showed positive in 75%, 78% of which showed positive reaction compounded of 2 kinds or more. 3. If we take a look at the distribution of total IgE class in the positive area, we can find that; Class 3 l and class Il showed the highest frequency as 47% and 37% respectively. 4. If we take a look at the distribution by age and allergen, the twenties(32% ) and the thirties(30%) showed the highest frequency, the fifities, the forties and the teens showed middle frequency as 10 13% and the sixties and the seventies showed the lowest frequency as about 1%. The causat ive allergen appeared in the order of pollen(40%), dust(20%), food(18 % ), fungus(13% ) and epidermis(8% ). 5. The distribution of allergen by season generally showed high rate of positive appearance in spring and fall as pollen appeared in spring(44%) and fall(27%), dust appeared in fall(32%) and summer(23%), food appeared in spring(34% ) and fall (29% ), fungus appeared in fall(.30% ) and spring(28% ) and epidermis appeared in spring(30%) and fall(28 %) 6. With regard to the allergen.' (1) In pollen allergens, trees showed higher positive frequency than weeds and trees were in the order of birch(14%), alder(13%) and hazelnut mix(12%) and weeds showed similar positive values. (2) In dust allergens, mite(D. pteronyssinus and D. farinae) showed high positive rate as 39% each. (3) In epidermal allergens, it also showed relatively even positive value among which cats hairdandruff was the highest as 40%. (4) In food allergens, shrimp showed the highest as 22 % and others were similar as evenly positive values. (5) In fungus allergens, Candida and Stemphylium showed the highest value as 19 % each. Conelusion: The analysis of allergen by means of MAST could be used as a valuable guide post for identifging cousative antigens for active treatment of extrinsic asthma.
신옥식,신규창,이병삼,장재권,정홍수,정태호,조용근,오용구 대한내과학회 1993 대한내과학회지 Vol.44 No.6
음주력이나 담도 질환없이 15년동안 반복적인 췌장염을 앓아온 45세 남자 환자에서 특별한 원인을 찾을 수 없는 심한 고지질혈증 특히 중성 지방의 현저한 증가를 관찰하였고, 체중 감량, 저지방식, 투약 등으로 중성 지방의 감소와 더불어 증상의 호전을 보인 예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. For a long time, it is well known that hyperlipidemia and pancretitis is closely related, though we could not define clearly whether the lipid abnormalities are the cause or the result of the pancreatitis. In patients with hyperlipidemia and pancreatitis, the recurrent bouts of pancreatitis are controlled only when serum triglyceride levels are lowered toward normal. A 45-year old man with abdominal pain due to pancreatitis was admitted. For 15 years, he had frequent relapse of pancreatitis. He denied any history of alcohol ingestion. On routine laboratory examination, we could find no abnormal finding except lactescent serum with marked hypertriglyceridemia up to 35 mmol/L, hypercholesterolemia and increased serum amylase level. With low fat diet, weight reduction and gemfibrozil 1,200㎎/day, he is now pain free and his serum triglyceride level is about 5.3 mmol/L (465㎎/dL).
주남영,도복태,임원준,석욱,오용창,김명준,우종길,정정명 인제대학교 1998 仁濟醫學 Vol.19 No.1
총수담관 막양구조는 1939년 Carter 등에 의해 처음 보고된 이래 세계적으로는 약40예, 국내는 아직 많이 보고되지 않은 드문 질환이다. 저자들은 열을 동반하지 않고 황달 및 심와부 동통을 주소로 내원한 56세 남자 환자에서 내시경적 역행술로 진단하고 수술로 치료한 총수담관 막양구조 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Common bile duct(CBD) web is a very rare disease. Since its first description in 1939 by Carter, about 40 cases have been reported in the world. This was found in a 56-year-old man who had the epigastralgia and jaundice without fever. He was diagnosed as CBD web by endoscopic retrograde cholangio-pancreatography (ER-CP) and treated with operation. We report this rare case with the review of literature.
급성 복통 및 호흡기 증상이 현저한 알레르기성 육아종증 1례
김명준,윤선희,김국규,오용창,주남영,임외자,우종길 대한알레르기학회 1995 천식 및 알레르기 Vol.15 No.4
Churg-Strauss syndrome is a disorder of hypereosinophilia and systemic vasculitis in subjects with asthma and allergic rhinitis. Clinically multiple organ systems can be involved with various manifestations of disease of lung, heart, skin, musculoskeletal system, and gastrointestinal, hepartobiliary tt act. Ive experienced a case of Churg-Strauss syndrome presenting as acute abdol men in a 54-year-old male. During the period of treatment, we observed migrating pneumonic infiltration and mechanical obstruction of small intestine. We performed exploratory laparotomy and small bowel resection. We observed granulomatous vasculitis of small and medium sized mesenteric vessel and marked eosinophilic infiltration in the small intestinal biopsy. We prescribed dexamethasone 10mg/day for patient. Patients symptom is resolved and then discharged.
최영식,김현주,이철희,박요한,편준철,박달수,정효균,안수열,전진숙,오용창,김형주 대한내분비학회 1998 Endocrinology and metabolism Vol.13 No.4
Lithium has been established as a drug useful for the treatment of manic depressive disorder. It is now well recognized that long-term administration of this drug is associated with various antithyroid effects such as goiter, and subclinical and overt hypothyroidism. However, it has been associated less commonly with thyrotoxicosis. Recently we experienced a case of thyroitoxicosis during lithium therapy. A 24-year-old man treated with lithium carbonate 900 mg-1,200 mg/day for manic-depressive illness for four weeks. He then complained of nervousness, palpitation, tremor, heat intolerance, and sweating. Neck pain was not noted. At that time the results of thyroid function test were consistent with hyperthyroidism: T3 568.8 ng/dL, TSH 0.01 mU/mL, FT4 6.0 ng/dL, but 24 hr radioiodine uptake was 0.3%. We suspected this case as lithium induced thyrotoxicosis and discontinued lithium administration. After discontinuation of lithium thyrotoxic symptoms were subsided. One month later, thyroid hormon levels became normalized: T 100.2 ng/dL, TSH 0.06 mU/mL, FT4 0.97 ng/dL and 24hr radioiodine uptake was 16%. We report this case with review of literatures (J Kor Soc Endocrinol 13:629-633, 1998).
이종곤(Jong Kon Lee),이병삼(Byung Sam Lee),신옥식(Ok Shick Shin),신규창(Kyu Chang Shin),오용구(Yong Ky Oh),기세길(Se Gil Ki) 대한내과학회 1991 대한내과학회지 Vol.41 No.4
N/A Tsutsugamushi disease is an acute febrile disease which is characterized by fever, headache, rash, and eschar. In Korea, there has been an increasing concern over rickettsiosis since Tsutsugamushi disease among Koreans was first reported in 1986. We experienced 75 cases of Tsutsugamushi disease that occurred during the periods of October-November, 1989, 1990. They which were confirmed by indirect immunofluorecent antibody test and their clinical findings were analized. Of 75 cases, 28 were males and 47 were females. The mean age was 50 years. The main symptoms and signs were headache, myalgia, fever, rash, and eschar. Characteristic laboratory findings included hypoalbuminemia, elevation of SGOT, proteinuria and interstitial pneumonia on chest X-ray. The mean duration of defervescence of fever was l. 4 days with tetracycline therapy and 1,25 days with chloramphenicol therapy. All cases improved and there were no recurrences.