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      • 알레르기 질환 예방을 위한 7대 권장사항

        민경업 대한알레르기학회 1999 천식 및 알레르기 Vol.19 No.5

        첨단 과학의 발전에 따른 질병 발생에 관한 병태생리의 이해와 새로운 치료약제의 도입에도 불구하도 알레르기 질환은 최근 20년 사이에 전세계적으로 증가하고 있는 추세이다. 국내에서도 암, 만성 성인병과 더불어 국민의 3대 만성 질환의 하나이고 소아에서는 이제 가장 흔한 만성 질환으로 알려져 있다. 1972년 대한알레르기학회가 창립되고 1981년 '알레르기' 학회 잡지가 발간되면서 알레르기 질환의 발생, 진단, 치료, 예방 등에 대한 관심이 증가하여 알레르기 여러 분야에서 논문들이 활발하게 보고되기 시작하였으며 여러 가지 학술활동 및 환자와 가족들을 위한 알레르기 교육이 시작되었다. 그러나 이러한 활동은 주로 알레르기 전문 클리닉이 설치되어 있는 병원들에 내원한 환자들을 대상으로 시행되었기 때문에 알레르기 질환의 증가 추세와 비교할 때 부족한 감이 있었다. 이에 대책으로 대한 천식 및 알레르기학회는 대한 소아알레르기 및 호흡기학회와 공동으로 1999년 5월 15일부터 21일까지 1주간을 제1회 알레르기주간으로 제정하고 다가오는 21세기에는 알레르기 질환의 발병을 줄이기 위하여 알레르기 예방을 위한 "7대 권장사항"을 채택하였다 (Table.1). 이는 알레르기질환의 발볍에 영향응 미치는 인자들 중 학문적으로 그 중요성이 널리 인정된 것들을 국내의 상황에 맞게 채택하였다. 이에 이러한 캠페인의 전체적인 필요성과 각 항목의 선정 배경을 밝히고자 한다.

      • 증례 : 캐슈 섭취 후 발생한 식품알레르기 1예

        김미영 ( Mi Yeong Kim ),강민규 ( Min Gyu Kang ),이서영 ( Suh Young Lee ),강성윤 ( Sung Yoon Kang ),심은진 ( Eun Jin Shim ),정재우 ( Jae Woo Jung ),강혜련 ( Hye Ryun Kang ) 대한천식알레르기학회(구 대한알레르기학회) 2011 천식 및 알레르기 Vol.31 No.3

        Background: Cashew (Anacardium) is a tree nut allergen which can induce severe symptoms, including anaphylaxis. However, only a few cases of tree nut allergies have been reported in Korea and Japan. We experienced a case of cashew allergy. Case History: A-27-year-old female patient presented with facial urticaria, lip edema, conjunctiva injection, nausea, vomiting, and voice change after eating cashew. The patient suffered from recurrent symptoms after eating food containing cashew. Results: We measured specific immunoglobulin E (IgE) to various tree nuts in serum using the Pharmacia CAP system and confirmed a marked increase of serum specific IgE to cashew and pistachio. However, allergic reactions occurred only after ingestion of cashew. Conclusion: We report a case of cashew allergy confirmed by the typical clinical history and specific IgE test. (Korean J Asthma Allergy Clin Immunol 2011;31:215-218)

      • 알레르기 질환 환자에서의 알레르기 반응도와 인성 특성의 관계

        김조자,김용순,박지원,강성숙,홍천수,이기영,박인용,민성길 대한천식알레르기학회 1989 천식 및 알레르기 Vol.9 No.2

        The differences of psychologic tests were found between groups of allergic diseases, who noted the degree of skin reactivity on allergy skin test. In the present study the MMPI and allergy evaluations were given to 115 patients with bron- chial asthma, allergy rhinitis, both of them and other allergic diseases, who visted at Allergy Clinic in Severance Hospital, Yonsei University College of Medicine from March 1988 to September 198K There were differences of personality charac- teristics between groups of allergic reactions. The weak skin reactivity group scored higher on depression, psychasthenia, social introversion (p<0.05) and feminity (in male patients)(p<0.01) and scored lower on psychopathic deviste than those of strong skin reactivity group. Therefore these findings confirm the previous conclusion that there are measurable, important psychological differences within groups of allergy patients, related to degree of demonstrable allergy reactivity. And allergy p a.tients had neurotic tendence. The patients who noted that their allergic simptom- developed on psychic stresses showed higher scores on hypochondriasis (p<0.05), depression (p 0.05) and hyste'ria (p<0.05) than those of the patients who did not note any relationship between development of allergy symptoms and psychic stresses. And the patients who noted that their allergy simptoms were relapsed by psye4ic stresses showed higher scores on hypochondriasis (p,0.05), depression (p <0.05), hysteria(p<0.01) and social introversion (p <0.05) than those of patients who noted that the relapse of their allergy symptoms was not related to psychic stresses. The results repremnt that psychic factors in addition to pure antigen-antibody reactions will participate in development and aggravation of allergy symptoms.

      • 알레르기성 비염 환자에서의 만성 부비동염 빈도에 대한 임상적 고찰

        강준명,최영철,원유성,신민호,서병도 대한천식알레르기학회 1992 천식 및 알레르기 Vol.12 No.4

        Nasal allergy is frequently associated with sinus disease, and it is believed that allergic rhinitis predisposes to sinus disease. The role of allergy in sinusitis is a pertinent yet unresolved issue. Radiological and allergological evaluation were performed on 179 patients, who complained of allergic symptoms, and who didnt have nasal polyp, mechanical and structural nasal obstruction, recent URI symptoms, during the period from August 1990 to August 1992 in Otolaryngologic Department of Kang Nam St. Marys Hospital. The results were as follows 1) Sinusitis was detected in 67 cases among 135 cases(49.6'%) in allergic group and 10 cases among 44 cases(22.7%) in non-allergic group. 2) There was a high prevalence of abnormal sinus X-ray in a population of allergic children. 3) In PNS X-ray findings, bilateral involvement of maxillary sinus was revealed as 47 cases(70.1'%) in allergic group. 4) Total blood eosinophil count was not related to incidence of sinusitis. 5) Wheal size for HD and DF, specific IgE level for DP and DF, eosinophil count in nasal secretion, serum IgE and symptom grading were related to incidence of sinusitis. 6) Specific IgG and IgG for DP and DF were not related to incidence of sinusitis. 7) In the allergic group, sinusitis was much more revealed in the patients who showed the positive skin test to house dust, house dust mite(perennial allergen) than to pollens(seasonal allergen),

      • Management of Food Allergy: Food Allergy Management Guideline 2005 by National Food Allergy Research Group Supported by the Ministry of Health, Welfare, and Labor

        ( Motohiro Ebisawa ) 대한천식알레르기학회 2006 천식 및 알레르기 Vol.26 No.3

        In October 2005, we released Food Allergy Management Guideline 2005. To cover food allergy from infancy to adulthood, the project committee included not only pediatric researchers, but also internists, dermatologists, and otolaryngologists. The guideline concept was to utilize the data accumulated by the National Food Allergy Research Group, to be plain and as short as a pamphlet, and to be released on internet. The most glowing argument was about relation between infantile atopic dermatitis and food allergy, and how it should be treated in the guideline. To avoid neither overvaluation nor undervaluation, fastidious care was given to the denotation. With the definition of infantile atopic dermatitis associated with food allergy, both dermatologic and pediatric members of the project committee finally came to agreement, which was a landmark between dermatologists and pediatricians in Japan. The guideline explains fundamentals with the least paragraphs and with tables and figures as many as possible. Flowcharts are made largely as a composition in the parts of diagnosis and treatment. I really hope that this guideline is useful for Korean doctors involved in food allergy and that quality of life of food allergy patients and their parents are improved. (Korean J Asthma Allergy Clin Immunol 2006;26:177-185)

      • KCI등재

        구강알레르기증후군

        최정희 ( Jeong-hee Choi ),이창률 ( Chang Youl Lee ) 대한천식알레르기학회(구 대한알레르기학회) 2018 Allergy Asthma & Respiratory Disease Vol.6 No.2

        Oral allergy syndrome (OAS) is an IgE-mediated allergy caused by cross-reacting antigenic determinants in pollens and various fruits, vegetables, and nuts which are known as the most common food allergy in adults. Cross-reactive antigenic proteins include pathogenesis-related-10 protein, profilin, cross-reactive carbohydrate determinant and lipid transfer protein. The prevalence of OAS has been reported at up to 70% of birch pollen allergy. A nationwide multicenter study in our country has recently reported that the prevalence of OAS in Korea is 41.7% of pollen allergy. Typical symptoms of OAS are tingling, itching sense and edema of lips, mouth, and throat immediately after ingestion of raw fruits, vegetables, or nuts. These can progress to systemic symptoms including anaphylaxis. The diagnosis can be made by typical clinical history in patients with pollen allergy. Skin prick test using fresh fruits extracts can be helpful in confirming sensitization to foods, which has better sensitivity than commercial skin prick test or serum specific IgE test. Treatment of OAS is to avoid causative foods. Self-injectable epinephrine should be considered in the case of anaphylaxis. Allergen-specific immunotherapy to pollens has also been tried. (Allergy Asthma Respir Dis 2018;6:85-89)

      • KCI등재후보

        Evaluation of Banana Hypersensitivity Among a Group of Atopic Egyptian Children: Relation to Parental/Self Reports

        Zeinab A. El-Sayed,Dalia H El-Ghoneimy,Dina El-Shennawy,Manar W. Nasser 대한천식알레르기학회 2013 Allergy, Asthma & Immunology Research Vol.5 No.3

        Purpose: To evaluate the frequency of banana sensitization and allergy among a group of atopic Egyptian children in relation to parental/self reports. Methods: This is a case-control study included 2 groups of allergic children with and without history of banana allergy, each included 40patients. They were subjected to skin prick test (SPT) using commercial banana allergen extract and prick-prick test (PPT) using raw banana, in additionto measuring the serum banana-specific IgE. Oral banana challenge was performed in suspected cases. Results: Banana allergy was diagnosedin 3 (7.5%) patients based on positive history of allergy on exposure to banana, positive SPT/PPT and elevated banana-specific IgE. The 3 patientshad bronchial asthma with exacerbation upon banana exposure. The PPT results conform with those of SPT both in diagnosis of banana allergy andin the skin reactivity to banana. Serum banana-specific IgE was detectable in the whole studied sample with higher serum level among those withouthistory of banana allergy (P=0.005). Oral banana challenge was negative for 20 patients with history of banana allergy and positive serum banana-specific IgE but negative SPT and PPT. Conclusions: Self/parental reports of banana allergy is high while the actual banana allergy is uncommon. The PPT seems as reliable as SPT in diagnosis of banana allergy unlike specific IgE which reflects sensitization rather than allergy. Oralfood challenge remains the most helpful tool for diagnosis of food allergy in suspected cases.

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