진료실에서 환자 호칭과 의사 복장 선호도

안성후,최민규,노용균,정지혜,진종원,김현철,김세중 대한가정의학회 2008 Korean Journal of Family Medicine Vol.29 No.5

Preferences for Addressing Title to Patients and Physicians' Attire in a Medical OfficeSeong Hoo Ahn, M.D., Ji Hye Jung, M.D., Jong Won Jin, M.D., Hyun Chul Kim, M.D., Se Jung Kim, M.D., Min Kyu Choi, M.D., M.P.H., Yong Kyun Roh, M.D., Ph.D. 연구배경: 건강 문제로 병원을 찾는 환자는 낯선 병원 환경과 의료진을 만나게 된다. 심리적으로 불안한 환자에게 의사의 호칭, 인사법, 복장 등의 태도는 의사 신뢰도에 영향을 줄 수 있다. 진료실에서 의사의 호칭, 인사법, 복장에 대한 환자의 선호도와 의사의 행태 간의 차이를 알아보기 위하여 연구를 실시하였다. 방법: 일개 대학병원에서 20대 이상의 외래 환자 394명과 5개 대학병원 전문의 169명을 대상으로 설문 조사하였다. 설문을 통해 환자호칭, 초면/구면 인사법, 선호하는 진료 복장과 의사의 복장이나 태도가 의사 신뢰도에 미치는 영향에 대해 환자군과 의사군을 구분하여 조사하였다. 결과: 환자군은 의사가 ‘OOO님’(51.0%), ‘OOO씨’(29.2%), ‘환자분’(16.2%), ‘선생님’(2.5%), 순으로 자신을 불러주길 원했다. 이에 반해 의사들은 호칭으로 ‘환자분’(39.2%), ‘OOO님’(29.6%), ‘OOO씨’(24.5%), ‘선생님’(1.2%) 순으로 환자를 부른다고 하여, 양군 간에 유의한 차이(P<0.001)를 보였다. 환자군과 의사군 모두에서 가장 선호하는 진료복장은 흰 가운(환자 70.3% vs 의사 78.7%)이었으며, 환자군에서는 흰 가운 다음으로 컬러가운(25%)을 선호하였다. 가운 안 복장으로는 양 군 모두에서 ‘와이셔츠와 넥타이’를 가장 선호(환자 66.2% vs 의사 71.6%)하였다. 의사군에서 의사의 태도(23.1% vs 45.6%) 및 복장(49.7% vs 55.6%)이 환자가 의사를 신뢰하는 데 '많이 영향을 준다'는 의견이 유의하게 높았다. 결론: 진료실에서 환자들은 ‘OOO님’으로 불리기 원하나 의사들은 ‘환자분’이라는 호칭을 많이 쓰고 있으며, 의사 복장은 양군에서 모두 흰 가운을 선호하였다. 의사의 태도나 복장이 의사 신뢰도에 영향을 미치는 것으로 나타났다.

궁하탕정의 단회 경구투여 후 안전성 평가를 위한 단일기관 연구

안성후,신희라,박경태,이윤승,김종규,염승룡,권영달,조혜영 한방재활의학과학회 2019 한방재활의학과학회지 Vol.29 No.4

Objectives The purpose of this study is to evaluate the safety of Gunghatang tablet in healthy male volunteers. Methods Single center pharmacokinetics study was carried out in healthy male volunteers. Through the laboratory test, vital sign and adverse event data, safety evaluation was conducted. Total 15 of 16 subjects who met the inclusion criteria were enrolled and three subjects were allocated to waiting group. 12 subjects were allocated by serial number according to registration order. Subjects took the maximum daily dose of the tablet on the second day of hospitalization. For the evaluation of safety, blood samples were collected and vital sign were checked 4 times (screening, before administration, after administration and follow up period) during the trial. All adverse events were recorded and summarized as frequency and percentage. All continuous data were summarized as mean and standard deviation. For comparison of variables between before administration and after administration, data were analyzed by paired T-test or Wilcoxon signed rank test (p<0.05). Results As a result of all data related to vital sign and laboratory test in both group, there were no significant differences associated with the clinical trial drug between pre and post administration. And there was no adverse event associated with the clinical trial drug. Conclusions Gunghatang tablet were found to be safe for healthy male volunteers. (J Korean Med Rehabil 2019;29(4):101-108)

靈仙除痛飮이 Monosodium Iodoacetate로 유도한 흰쥐의 골관절염에 미치는 효과

안성후,정영진,김수학,이학송,염승룡,권영달 한방재활의학과학회 2023 한방재활의학과학회지 Vol.33 No.4

Objectives The anti-inflammatory and anti-arthritic effects of Youngseonjeatonguem (靈仙除痛飮, YSJTU) was evaluated in a cellular model using RAW264.7 macrophages, which are involved in osteoarthritis (OA), and an animal model using Sprague-Dawley (SD) rats, and a possible mechanism of anti-arthritic actions of YSJTU was presented. Methods RAW264.7 macrophages were activated by lipopolysaccharide (LPS). The production of pro-inflammatory cytokines (tumor necrosis factor [TNF]-α, interleukin [IL]-1β, and IL-6) and inflammatory mediators (nitric oxide [NO] and prostaglandin E2 [PGE2]) was determined by ELISA and Griess assay, respectively. Western blot was performed to determine inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression. OA was induced by intra-articular injection of monosodium iodoacetate (MIA) into the right knee joint of SD rats. Results In RAW264.7 macrophages, YSJTU reduced LPS-induced production of TNF- α, IL-1β, and IL-6. In addition, YSJTU inhibited LPS-induced production of NO and PGE2 by suppressing iNOS and COX-2 expression. In SD rats, YSJTU improved MIA-induced OA by reducing swelling, skin heat, and cartilage degradation. In addition, YSJTU reduced serum levels of TNF-α, IL-1β, and IL-6, along with its significant decrease in serum levels of NO and PGE2. Conclusions These results suggest that YSJTU may exert anti-arthritic effect, at least in part, by inhibiting macrophage-mediated joint inflammation. (J Korean Med Rehabil 2023;33(4):1-14)

제5 중족골 근위부 견열골절 환자의 복합 한의치료 효과

안성후 ( Sung-hu An ),정영진 ( Yeong-jin Jeong ),염승룡 ( Seung-ryong Yeom ),권영달 ( Young-dal Kwon ) 한방재활의학과학회 2021 한방재활의학과학회지 Vol.31 No.2

The purpose of this study is to report the effect in treating a patient with a case of avulsion fracture of the proximal 5th metatarsal with a combination of Korean medicine therapy. We treated the patient with acupuncture, pharmacopuncture, moxibustion, cupping, and herbal medicine The numeric rating scale, X-ray were applied as outcome measures. After complex Korean medicine treatment, this patient's avulsion fracture of the proximal 5th metatarsal was improved and pain was reduced. This result shows that Korean medical therapy may be an effective option for avulsion fracture of the proximal 5th metatarsal. (J Korean Med Rehabil 2021;31(2):109-114)

보중익기탕연조엑스의 1회 경구투여 후 안전성 평가에 관한 단일기관 연구

안성후 ( Sung-hu An ),정영진 ( Yeong-jin Jeong ),김종규 ( Jong-gyu Kim ),신혜령 ( Hyeryung Shin ),권영달 ( Young-dal Kwon ) 한방재활의학과학회 2021 한방재활의학과학회지 Vol.31 No.4

Objectives This study is designed to evaluate the safety of Bojungikgi-tang soft extract in healthy male volunteers. Methods 12 healthy male volunteers were recruited and this study was carried out by a single center. Laboratory test results, vital signs of the volunteers were collected to evaluate safety. According to registration order, the 12 subjects were allocated by serial number. To evaluate safety, blood samples were taken and vital signs were checked 4 times - screening, pre administration, post administration and follow up-during the whole trial. The difference between pre (before medication [0 hr]) and post-administration (after medication [48 hr]) variables was summarized as mean±standard deviation. The normality test was performed using the Kolmogorov-Smirnov test and Shapiro-Wilk test. When the normality is satisfied, the paired t-test is applied. Otherwise, the non-parametric method, Wilcoxon signed rank test is applied. The significance level was p<0.05. The incidence of all adverse effects are shown in percentage. Results In the case of red blood cell, hemoglobin, hematocrit, lymphocytes, neutrophils, protein, γ-glutamyl transpeptidase values, the normality test result of the variable for the difference value before and after the dosing has a significance level <0.05. But most of values did not deviate from the normal range, and the deviation from the normal range could not be regarded as the significance associated with this clinical trial. And adverse event wasn’t observed associated with the clinical trial drug. Conclusions Bojungikgi-tang soft extract were considered to be safe for healthy male volunteers. (J Korean Med Rehabil 2021;31(4):157-166)

열전달 향상 장치에 따른 평판형 태양열 집열기의 압력강하 및 열전달 특성

안성후(Sung-Hoo Ahn),신지영(Jee-Young Shin),손영석(Young-Seok Son) 한국마린엔지니어링학회 2013 한국마린엔지니어링학회지 Vol.37 No.5

소시호탕연조엑스의 단회 경구투여 후 안전성 평가에 대한 단일기관 연구

안성후 ( Sung-hu An ),박경태 ( Kyungtae Park ),염승룡 ( Seung-ryong Yeom ),권영달 ( Young-dal Kwon ),조혜영 ( Hea-young Cho ) 한방재활의학과학회 2020 한방재활의학과학회지 Vol.30 No.2

Objectives This study is designed to evaluate the safety of Soshihotang soft extract in healthy male volunteers. Methods 12 healthy male volunteers were recruited and this study was carried out by a single center. Laboratory test results, vital signs of the volunteers were collected to evaluate safety. According to registration order, the 12 subjects were allocated by serial number. To evaluate safety, blood samples were taken and vital signs were checked 4 times-screening, pre administration, post administration and follow up-during the whole trial. The incidence of all adverse effects are shown in percentage. The mean and standard deviation were used to to describe and summarize continuous data. To evalate the effectiveness of the intervention, data of blood tests was analyzed by Wilcoxon signed rank test or paired T-test (p<0.05). Results In the case of red blood cell, hemoglobin, hematocrit, neutrophils, protein, albumin, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, γ-glutamyl transpeptidase values, the normality test result of the variable for the difference value before and after the dosing has a significance level <0.05. But most of values did not deviate from the normal range, and the deviation from the normal range could not be regarded as the significance associated with this clinical trial. And adverse event wasn’t observed associated with the clinical trial drug. Conclusions Soshihotang soft extract were considered to be safe for healthy male volunteers. (J Korean Med Rehabil 2020;30(2):153-164)

말기신질환이 중증의 허혈성 대장염의 위험인자인가?

안성은 ( Sung Eun Ahn ),이항락 ( Hang Lak Lee ),조승철 ( Seung Chul Cho ),윤재훈 ( Jai Hoon Yoon ),이오영 ( Oh Young Lee ),윤병철 ( Byung Chul Yoon ),최호순 ( Ho Soon Choi ),함준수 ( Joon Soo Hahm ),이민호 ( Min Ho Lee ),이동후 ( 대한소화기학회 2009 대한소화기학회지 Vol.53 No.4

목적: 허혈성 대장염의 임상 경과는 다양하나 대부분 보존 치료로 2-3일 내에 호전되나 드물게 수술 치료가 필요한 경우, 사망하는 경우도 있다. 저자들은 심한 임상경과를 예측할 수 있는 예후 인자들에 대해 알아보고자 연구를 시작했다. 대상 및 방법: 2004년부터 2006까지 한양대학교병원에 허혈성 대장염으로 진단받은 환자 41명을 경증과 중증으로 나누어 후향 분석하였다. 결과: 환자들의 평균연령은 63.8세였고, 남자 13명, 여자 28명이었다. 음주력이 있는 환자는 10명이고 흡연력은 11명이었다. 환자들의 기저질환은 고혈압 24명, 당뇨병 14명, 혈액 투석 중인 말기 신질환 11명, 심혈관 질환 5명, 악성 종양 5명이었다. 약물 복용력은 항혈소판제 11명, 항고혈압제 21명, 비스테로이드 항염증제 5명이었다. 처음 발현한 증상으로 복통, 혈변, 설사, 복막자극징후, 내원 당시 혈액검사, 대장 내시경 또는 복부 전산화 단층촬영에서 대장 침범 부위로 나누어서 중증의 허혈성 대장염으로의 진행 여부를 살펴보았다. 중증의 임상경과를 보인 경우는 남자(p=0.049), 음주력(p=0.025), 말기 신질환이 있을 때(p=0.013), 검사실 소견에서 LDH (p=0.002), CRP (p=0.014) 수치가 의미가 있었다. 신체검진에서는 복막자극징후(p=0.000)가 유의한 의미가 있었다. 여러 위험인자를 포함한 로지스틱 회귀 분석에서는 말기 신질환이 중증 허혈성 대장염의 유일한 위험인자였다. 결론: 말기 신질환 환자에서 허혈성 대장염은 중증으로 발전할 가능성이 높다. 따라서 허혈성 대장염이 발생한 말기 신질환 환자에서는 주의가 필요하다. Background/Aims: In general, ischemic colitis has a very good prognosis. However, there are a lot of controversies in relation to the prognostic factors. The aim of this study was to evaluate risk factors of severe ischemic colitis. Methods: A retrospective study was undertaken of patients with ischemic colitis hospitalized at the Hanyang University Hospital during the interval 2004-2006. Patients were divided into two groups: those with mild course and those with severe course which led to operation, systemic inflammatory response syndrome, or death. Results: A total of 41 cases (M/F=13/28, mean age=63.8 years) of biopsy proven ischemic colitis were included, of which 31 (75.6%) had a mild course and 10 (24.4%) a severe course. Coexisting medical diseases of patients were hypertension (n=24), diabetes (n=14), end-stage renal disease (n=11), cardiovascular disease (n=5), and malignancy (n=5). Male (p=0.049), alcoholics (p=0.025), end-stage renal disease (p=0.013), LDH (p=0.002), CRP (p=0.014), and peritoneal irritation sign (p=0.001) were the significant risk factors of severe ischemic colitis in univariate analysis. In multivariate logistic regression analysis, end-stage renal disease (p=0.026) was the only significant risk factor of severe ischemic colitis. Conclusions: Careful attention must be paid to end-stage renal disease patients having ischemic colitis. (Korean J Gastroenterol 2009;53:235-238)

항암화학요법 유발 말초신경병증에 대한 한방치험 1례

신혜령,서욱철,안성후,원진희,송봉근,Shin, Hyeryung,Seo, Wookcheol,An, Sung-Hu,Won, Jin-hee,Song, Bong-keun 대한한방내과학회 2021 大韓韓方內科學會誌 Vol.42 No.2

Introduction: The aim of this study is to report on the effectiveness of Korean medicine to improve symptoms of chemotherapy-induced peripheral neuropathy (CIPN). Some patients are treated with medication, but medications may have no effect in some patients. Korean medicine treatments have been used in such patients, but few reports exist. Case Presentation: A 58-year-old female patient with CIPN reported symptoms of bilateral limb pain and tingling sensations as well as cold sensations in bilateral lower legs and hands, fatigue, and bilateral limb weakness. To reduce the patient's symptoms, we provided Korean medical treatment, including herbal medicine (Uchashinki-hwan), acupuncture, and moxibation. To evaluate the results of this treatment, we used a numeric rating scale (NRS), the manual muscle test (MMT), the National Cancer Institute Common Toxicity Criteria for Adverse Events (CTCAE), and the European Organization for Research and Treatment of Cancer quality-of-life questionnaire about CIPN (EORTC-QLQ-CIPN20). After 49 days of treatment, the NRS scores decreased for bilateral limb pain and tingling, for bilateral lower leg and hand cold sensation, and for fatigue. The MMT results for the upper and lower extremities were improved. CTCAE Grade and EORTC QLQ-CIPN20 score were also decreased. Conclusion: According to these results, Korean medicine treatment may be considered an effective treatment for CIPN. Prospective studies are needed in the future to confirm and expand these findings.

제 4족지 원위지골 골절 지연유합 환자의 복합 한의치료 효과

박경태,신희라,안성후,염승룡,권영달 한방재활의학과학회 2019 한방재활의학과학회지 Vol.29 No.4

The purpose of this study is to report the effect in treating a patient with delayed union of 4th toe distal phalanx fracture with a combination of Korean Medicine treatment. We treated the patient with acupuncture, cupping, pharmacopuncture, moxibustion and herbal medicine, from March 3, 2018 to June 25, 2018 (total 33 times). The numeric rating scale (NRS), X-ray were applied as outcome measures. After complex Korean medicine treatment was carried out, delayed union of 4th toe distal phalanx fracture was improved and pain was reduced. This result shows that Korean medicine treatment may be an effective option for delayed union. Further clinical studies are needed to clarify the effect of Korean medicine treatment on delayed union. (J Korean Med Rehabil 2019;29(4):143-149)