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최성재(Sung Jae Choi),지종대(Jong Dae Ji),송관규(Kwan Kyu Song),이영호(Young Ho Lee) 대한내과학회 1999 대한내과학회지 Vol.56 No.6
N/A Objectives : It was reported that fatigue was the seventh most common symptom in primary care and 24% of the general adult population had fatigue lasting 2 weeks or longer in the united states. No medical cause was found in 59% to 64% of those persons. Chronic fatigue syndrome is chracterized by debilitating fatigue of at least 6 months duration accompanied by other symptoms such as fever, pharyngitis, painful lymph nodes, headache, myalgia, sleep disturbances, neurocognitive complaints, and depression. Idiopathic chronic fatigue is defined as clinically evaluated, unexplained chronic fatigue that fails to meet criteria for the chronic fatigue syndrome. The objectives of this study were to determine the prevalence of idiopathic chronic fatigue and chronic fatigue syndrome (CFS) in Korea and to analysis the symptoms of those patients. Methods : Five hundred thirty persons who visited Korea university hospital health management center between March 1998 and June 1998 were participated in the study. The questionnaire made according to the Centers for Disease Control and Prevention criteria was administerd and patients with idiopathic chronic fatigue and chronic fatigue syndrome were diagnosed by this questionnaire, physical examination and laboratory tests. Results : Ten persons(1.9%) met the criteria for chronic fatigue syndrome. and 115 persons (21.7%) met the criteria for idiopathic chronic fatigue. The symptoms in patients with chronic fatigue syndrome were memory loss or forgetfullness(90%), sore throat(20%), painful lymph node(30%), myalgia(80%), multiple arthralgia(20%), headache(50%), unrefreshing sleep(100%), postexertional malaise(90%). Conclusion : Persons who met the criteria for chronic fatigue syndrome were found in 1.9% . The incidence of chronic fatigue syndrome in our study was high, compared with previous studies.
이창홍(Chang Hong Lee),김진호(Jin Ho Kim),송관규(Kwan Kyu Song) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.1
N/A Levels of antibody to hepatitis B surface antigen (anti-HBs) were measured in thirty young healthy volunteers given 20 ug dose of Korean Green Cross plasma derived hepatitis B vaccine (Hepavax B ) monthly at 0, 1, 2 month schedules. Blood samples were removed monthly for three months after injection of 1st dose vaccine and tested for anti-HBs by radioimmunoassay. Antibody (anti-HBs) conversion rate was elevated up to 93% one month after third dose injections in these volunteers and geometrical mean antibody titers expressed as ratio units were 37.3 RU at this period (>10 RU: 76%). There was no sigificant difference in immunogenecity between the 2 month and the recommended 6 month schdeules, the shorter schedule is likely to be more convenient in certain situation, such as mass hepatitis B vaccination.
급성심근경색증에서 정맥내 투여 Urokinase 의 혈전용해 효과
노영무(Young Moo Ro),오동주(Dong Joo Oh),심완주(Wan Joo Shim),최석주(Suck Joo Choi),송관규(Gwan Gyu Song),박창규(Chang Kyu Park),유승관(Seung Kwan Ryu),서순규(Soon Kyu Suh) 대한내과학회 1988 대한내과학회지 Vol.34 No.2
N/A To evaluate the thrombolyutic efficacy and safety of Urokinase (UK), an intravenous (IV) bolus of 20,000 units/kg was administered in 15 patients with acute evolving transmural myocardial infarction 6.15(2.5~8.0) hours after the onset of symptoms. Recognition of myocardial reperfusion was based upon the reperfusion scores according to the following indirect clinical criteria; rapid relief of chest pain, rapid resolution of ST segment elevation (∑ST reduction by ? 70%within 90 minutes), ischemic arrhythmia or A-V block and CK wash-out phenomenone, Signs of reperfusion began to occur 30 to 90 minutes after the IV bolus of UK. Of the 15 patients, 8(53.3%) had one or more of the signs of reperfusion and 6 (40%) had reperfusion scores of ?4, which indicates definite reperfusion according to the indirect reperfusion scoring system we employed. Those who received UK within 6 hours after the onset of chest pain, reperfusion was achieved in 71.4% (5 of 7 patients). Transient gum bleeding was the only side effect, which was seen in 1 patient (6.7%). These findings suggest that IV bolus of 20,000 units/ kg UK within 6 hours after the onset of chest pain is an effective and safe method to achieve reperfusion in patients with acute transural myocardial infarction. Since there was no significant complication on 20,000 units/kg of UK, higher dose than 20,000 units/kg can be used to improve reperfusion in acute evolving myocardiaI infarction,
증례 : 류마티스 ; 직장-S상 결장접합부 거대 궤양을 통해 진단된 전신홍반 루푸스 1예
유인경 ( In Kyung Yoo ),유서희 ( Seu Hee Yoo ),최성재 ( Sung Jae Choi ),구자설 ( Ja Seol Koo ),이영호 ( Young Ho Lee ),지종대 ( Jong Dae Ji ),송관규 ( Kwan Kyu Song ) 대한내과학회 2012 대한내과학회지 Vol.82 No.2
저자들은 비특이적인 위장 증상으로 내원한 전신홍반루푸스 환자에서 S상결장 부위의 부분-완전 폐색을 동반한 커다란 직장궤양을 발견하였고, 기저 질환으로 루푸스를 진단하고 경구스테로이드 치료로 호전되었기에 이를 보고하는 바이다. Systemic lupus erythematosus (SLE) is a multi-system inflammatory disorder that has many symptoms. Gastrointestinal symptoms are common, while colonic involvement in the form of ischemic colitis or a colonic ulcer is rare in SLE. The differential diagnosis of ischemic proctitis with ulceration includes an infected ulcer, ulcerative colitis, Crohn`s disease, solitary rectal ulcer colitis, malignant tumor, and lupus colitis. Here, we report a 22-year-old male with abdominal pain and diarrhea, who had a huge rectal ulcer that nearly obstructed the rectosigmoid junction. This turned out to be a rare gastrointestinal manifestation of lupus. He recovered after being treated with high-dose oral steroids. Our case demonstrates that a rectal ulcer is a rare, but important, complication of SLE and can be the initial clinical manifestation of the disease. (Korean J Med 2012;82:252-256)
이홍식,김승주,김창덕,류호상,현진해,김광희,송관규,지종대 대한소화기학회 1998 대한소화기학회지 Vol.32 No.3
Systemic lupus erythematosus (SLE) is a multisystem disease with a variety of clinical manifestations. The development of the disease is often variable and characterized by repeat of exacerbation and remission. Dming the course of their illness, thirty-five to forty pereent of patients with SLE show signs or symptoms of gastrointestina1 involvement. We report two cases of acute panneatitis associated with SLE. The patient of the case 1 was a 27-year-old female who was admitted after 1 day of seizure and epigastric pain. Brain MRI showed normal findings and Abdominal CT showed mild pancreatic enlargement. The symptoms were improved with treatment, The patient of the case 2 was a 33-year-old female who complained of epigastric pain. Abdominal sonography showed mild pancreatic enlargement. The condition of the patient was improved with conservative treatment.