인플루엔자 감염과 열성경련의 연관성에 관한 연구

손영수(Young soo Sohn),권순학(Soon hak Kwon),문정은(Jung eun Moon),안지영(Ahn Ji Young),김정은(Kim Jung Eun),백희선(Baek Hee Sun) 대한소아신경학회 2014 대한소아신경학회지 Vol.22 No.3

Purpose: Febrile seizures are common in children between the ages of 6 months and 5 years of age and are often caused by viral illnesses. Influenza infection presents with a variety of neurological conditions including seizures. This study was aimed to evaluate the correlation of influenza infection and febrile seizures. Methods: Eighty-four children with febrile seizures were involved in the study from October 2013 to March 2014. They were divided into two groups (febrile seizures with influenza infection, febrile seizures without influenza infection). Their medical records including clinical characteristics such as seizure types, seizure frequency, seizure duration, developmental history, brain magnetic resonance imaging(MRI), cerebrospinal fluid(CSF) study and electroencephalogram(EEG) findings were reviewed. Results: Twenty six out of 242 children between the ages of 6 months and 5 years diagnosed with influenza infection had febrile seizures (10.7%), which is higher than known prevalence of febrile seizures. There were no significant differences in clinical characteristics such as seizure types, seizure frequency, seizure duration, developmental history, brain MRI, CSF study and EEG findings between the two groups. However, onset age of febrile seizures with influenza infection was older than the other group without influenza infection(P<0.001). Conclusion: It has been considered that influenza infections are common during the cold seasons and are the main causative factor for febrile seizures. Based on the findings from this study, Influenza infection may be a significant risk factor for febrile seizures. However, further studies are needed.

속발성 무월경 외 비정상 표현형이 없는 Trisomy 8 Mosaicism의 증례 보고

강혜심(Hye Sim Kang),손영수(Young Soo Son),김성엽(Sung Yob Kim),박철민(Chul Min Park),심순섭(Soon Sup Shim) 대한의학유전학회 2011 대한의학유전학회지 Vol.8 No.1

체질성 8삼염색체 모자이시즘은 비교적 드문 염색체 이상으로 특이한 두개안면 모양 (변형 두개골, 돌출된 이마, 낮거나 변형된 귀), 골격계 기형, 심장 기형, 신장 기형, 잠복고환, 다양한 정도의 발달지체 등의 특징적인 표현형을 갖는다. 그 표현형과 세포유전학적 표현의 다양성 때문에 특정 질환이 생기기 전까지 진단이 늦어지기도 한다. 전형적인 표현형 없이 속발성 무월경을 동반한 28세 여성에서 발견된 체질성 8삼염색체 모자이시즘(47,XX,+8[9]/46,XX[41])을 보고한다. Constitutional trisomy 8 mosaicism (CT8M) is a relatively rare aneuploidy in humans with characteristic phenotypes including typical craniofacial feature (such as deformed skull, prominent forehead, low-set and/or dysplastic ears), skeletal malformation, cardiac anomaly, renal malformation, cryptochidism, varying degree of developemental delay. Due to the extremely variable phenotypic and cytogenetic expression, CT8M has gone undiagnosed in certain patients. We report a 28-year-old women with secondary amenorreha without characteristic CT8M phenotype. Chromosomal analysis showed a CT8M (47,XX,+8[9]/46,XX[41]).

자폐증유아의 치료과정에 대한 이해와 반성

강인언 ( Kang In-eun ),손영수 ( Soon Young-soo ) 한국유아특수교육학회 2002 유아특수교육연구 Vol.2 No.1

본 연구는, 자폐증 유아들의 제 특성을 중심으로 자폐증 유아들을 치료하는 과정에서 치료교사와 유아와의 관계, 자폐증 치료프로그램, 그리고 프로그램의 적용을 중심으로 하여 자폐증유아들이 어떻게 변화·성장해 가는지와 이러한 치료 프로그램이 자폐증 유아의 치료에 어떤 의미를 가지게 되는지를 현상학적 해석학의 시각에서 이해함으로써 자폐증 유아를 존재론적으로 살펴보았다. 자폐증유아와의 친밀성 형성을 위한 강화제 먹기, 안아서 높이 들어주기, 그리고 산책하기 프로그램을 통하여 자신과 대상유아간의 긴장을 완화하고 신뢰관계를 형성하며, 대인관계를 개선해나간다. 이 세 가지 프로그램은 특정의 순서에 따라 진행되는 것이 아니라 유아의 상태에 따라 자유롭게 적용된다. 장애유아의 행동통제를 위한 불러 다가오기와 손잡고 걷기는 교사와 함께 있음을 지각하고 교사의 지시와 요구에 적절히 행동반응을 할 수 있도록 함으로써 행동 통제에 순응하도록 한다. 이러한 프로그램 과정을 통하여 자폐증유아는 성장하고 발전하며 변화해 간다. 지금까지 장애유아 치료교육을 담당하는 교사나 연구자들이 유아들을 기능적으로 훈련시키고 치료하는 데에만 초점을 맞추어왔지, 자폐증유아들을 존재론적으로 이해하려 하지 않았다. 본 연구는 자폐증유아의 치료과정을, 치료교사나 연구자들의 치료과정의 여러 특성과 관련지어, 자폐증유아의 입장에서 고찰하였다. This study attempts to ontologically inquire into autistic early children by understanding the meanings of the relationship between treating teachers and autistic early children, the application of the programme, and the programme itself to the process to treat them in the point of view of phenomenological hermeneutics. Treating teachers mitigate the tensions and grow confidence between themselves and autistic early children, and improve the autistic early children’s relationship with others by applying the programmes to make them eat some buildup food, hold them aloft in their arms, and go out for a walk with them. The three above- mentioned programmes are applied not strictly by a stereotyped order but very flexibly according to their conditions and emotions. By the process to call and make autistic early children be close and walk out hand in hand with them in order to control autistic early children’s behaviour, the autistic early children would be aware of their being with treating teachers and acclimate themselves to the treating teachers’ behaviour control by responding appropriately to their order and desire. By these programmes the autistic early children grow, change, and develop themselves. Until now,teachers and researchers to be charged with the treatment for autistic early children have the tendency to focus on training and curing them functionally and technically, not on the ontological understanding of them. This study tries to understand the process of the curing of autistic early children ontologically in their situation referring to the characteristics of itself.

매체동화가 특수아동의 정서발달에 미치는 교육적 함의에 대한 해석학적 연구

유강민 ( Gang Min Yu ),손영수 ( Young Soo Soon ) 한국특수아동학회 2009 특수아동교육연구 Vol.11 No.4

5-FU 연고로 치료한 절제면 양성 미세침윤성 외음부 파제트병 1예

강호정 ( Ho Jeong Kang ),박철민 ( Chul Min Park ),심순섭 ( Soon Sup Shim ),손영수 ( Young Soo Son ),김성엽 ( Sung Yob Kim ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.3

자궁경부 선암에서 고위험 인유두종바이러스 감염 양성도와 p53 단백 과발현의 관계

강석범 ( Sok Bom Kang ),이동옥 ( Dong Ock Lee ),손영수 ( Young Soo Son ),김재원 ( Jae Weon Kim ),박노현 ( Nog Hyun Park ),송용상 ( Yong Sang Song ),강순범 ( Soon Beom Kang ),이효표 ( Hyo Pyo Lee ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.10

목적 : 자궁경부 선암 가운데 HPV 음성 선암에서 p53의 돌연변이가 연관이 있는지 조사하고자 하였다. 연구 방법 : 1998년부터 2002년까지 서울대학교병원에서 자궁경부 선암을 조직학적으로 진단받고 근치적자궁절제술을 시행한 54명의 환자 중 의무기록검토가 가능하고 종양조식을 얻을 수 있는 50명의 환자를 대상으로 면역조직화학 염색을 통해 p53 유전자 변이를 판정하였고 HPVNDAChip을 이용해 HPV 검출을 시행하여 비교하였다. 결과 : 총 5 Objective : The aim of the present study was to analyze the relation between p53 mutation and cervical adenocarcinoma without HPV infection. Methods : From 1998 to 2002, 54 patients were diagnosed with cervical adenocarcinoma and underwent radical hystere

면역조직화학적 특성 및 미세현미경 구조적 연구가 시행된 Pulmonary type의 난소 소세포 종양 1예

이지영,손영수,김향미,김승철,성순희,한운섭 대한부인종양 콜포스코피학회 1998 Journal of Gynecologic Oncology Vol.9 No.3

난소의 소세포종양은 1982 년 Dickersin 등이 처음 보고하였으며 ,주로 젊은 여성에서 발생하는 드문 ,악성종양으로 알려져 있으며 현재까지 조직병리학적 연구와 미세현미경 구조 연구 및 면역 조직화학적 특성연구가 진행되고 있으나 아직 그 근원도 확실히 알려지지 못 하고 있다 .저자등은 Pulmonary type 의 난소 소세포암을 가진 36 세 환자에서 수술시행 후, 항암요법 ,방사선조사를 시행한 1 예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

질식초음파를 이용한 자궁경관무력증의 진단

이경순,류지아,송인옥,정혜원,안정자,손영수,정은철,우복희 梨花女子大學校 醫科大學 醫科學硏究所 1993 EMJ (Ewha medical journal) Vol.16 No.2

The diagnosis of cervical incompetency Is routinely accomplished by reviewing the clinicalhistory and pelvic examination subjectively. Rescently by using ultrasonography. the objectivemethod in diagnosis of cervical incompetency was developed. Especially, the transvaginal sonog-raphy can provide clear visualization of uterine cervix with an empty bladder without distrosionof cervix which was developed when abdominal sonography with distended bladder. So author performed the study in 46 cases of pregnant women of which menstrual agewas 12 weeks to 36 weeks(normal control group 36 cases, risk group 11 cases) during theperiod of May, 1992 to Febburary, 1993. And these two groups were performed trasvaginal sonog-raphy and measured length and diameter of cervix. And the result were follows ; 1) The mean age was higher in risk group than normal control group. the gestational agewas not significantly different between two groups, and the gravity and parity was higher inrisk group than normal control group. 2) As rneasuring the lengt and diameter of cervical canal by transvaginal sonogram innullipara and multipara in normal control group, each measurements were not significantlydifferent between nullipara and multipara. 3) The mean length of cervix by transvaginal sonography was 3.0±0.97cm in risk group,4.7±0.89cm in normal control group and the cervical length was significantly shorter in riskgroup than normal control group(P<0.01). 4) The mean diameter of cervix by transvaginal sonogram was 2.0±0.37cm in risk group,0.5±0.21cm in normal control group and the diameter of cervix was significantly greater inrisk group than normal control group(P<0.01). Transvaginal sonographic measurement of cervical length and diameter in diagnosis of incompetent internal os of cervix is noninvasive and relatively objective method.