Resource controller 자동 생성 시스템의 설계

손경철,김영주,김길창 한국정보과학회 1986 한국정보과학회 학술발표논문집 Vol.13 No.2(1)

본 논문에서는, 공유하고 있는 자원을 사용하는 operation 들 간의 동작을 제어 통제하는 resource controller 의 자동 생성 시스템을 설계하였다. 이 자동 생성 시스템은 Ramamritham 의 SYSL을 입력 서술 언어로 받아 들여, 병렬 프로그램 언어인 path pascal 로 된 프로그램은 resource controller 로 생성한다. Path pascal 의 특성상 condition synchronization 은 쉽게 표현할 수 없는데, 이를 해결하기 위한 기법도 아울러 제시하였다.

Trial Comparing a Combined Regimen of Amikacin and Ciprofloxacin to Ciprofloxacin Alone as Transrectal Prostate Biopsy Prophylaxis in the Era of High Fluoroquinolone-Resistant Rectal Flora

손경철,정호석,정승일,김명수,황의창,김진웅,권동득 대한의학회 2018 Journal of Korean medical science Vol.33 No.15

Background: To investigate whether addition of amikacin to fluoroquinolone (FQ) antimicrobial prophylaxis reduces infections after transrectal ultrasound-guided prostate biopsy (TRUSPB). Methods: A total of 503 patients undergoing rectal swab were divided into three groups. Patients with FQ-sensitive rectal flora (group 1, n = 248) were administered ciprofloxacin before TRUSPB, and patients with FQ-resistant rectal flora were either administered ciprofloxacin (group 2, n = 97) or amikacin and ciprofloxacin (group 3, n = 158) before TRUSPB. Results: Based on the rectal swab, FQ resistance was 54.9%, and extended-spectrum β-lactamase (ESBL) positivity was 17.2%. The incidence of infectious complication in group 1 was 1.6%. Groups 2 and 3, with FQ-resistant rectal flora, tended to have increased infectious complications (5.2% and 4.4%, respectively) but the difference between those results is not statistically significant. The most common pathogens of infectious complications in patients with FQ-resistant rectal flora were FQ-resistant and ESBL-producing Escherichia coli. E. coli pathogens isolated in Group 3 were amikacin-susceptible species. The operation history and ESBL positivity of rectal flora increased the incidence of infectious complications (odds ratio [OR] = 3.68; P = 0.035 and OR = 4.02; P = 0.008, respectively). DM and antibiotics exposure were risk factors for FQ resistance (OR = 2.19; P = 0.002) and ESBL positivity of rectal flora (OR = 2.96; P = 0.005), respectively. Conclusion: Addition of amikacin to ciprofloxacin prophylaxis could not reduce infectious complications in patients with FQ-resistant rectal flora. Despite the amikacin sensitivity of infectious complications, single-dose amikacin addition to ciprofloxacin prophylaxis has limitations.

Surface-Control Enhanced Crater-Like Electrode in a Gelatin/Polyvinyl Alcohol/Carbon Composite for Biodegradable Multi-Modal Sensing Systems with Human-Affinity

손경철,최형섭,박종진 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2

Gelatin has a triple helix structure in its solid-state capable of forming a self-assembly. Here, the pore sizeof the gelatin/polyvinyl alcohol (PVA)/carbon (GPC) blend can be modified through the PVA content which is configurable to obtain different properties like air/light transmissivity, high conductivity with the blend of graphite and carbon black, with only carbon black , surface energy, and strain for several applications. In this study, a new secret tag application based on a GPC blend porous structure is presented for the first time. The optimized GPC aqueous solution may not only be coated directly on human skin to form an emotion sensor or breathable touchpad without causing irritation but could also be made into a multi-modal sensor for human activity with biodegradability. The GPC free-standing electrode film also yields a stable triboelectric output (75 V) when used as a triboelectric nanogenerator (TENG) by varying the surface area.

Multifunctional Elbow and Knee Pad Sensor System Using Carbon Ink

손경철,안다혜,김준서,박상기,조유장,정재선,최형섭,박종진 한국고분자학회 2020 한국고분자학회 학술대회 연구논문 초록집 Vol.45 No.2

복압성요실금 흰쥐모델에서 요도주위 간엽줄기세포주입의 효과

손경철,김선옥,주수연,안영근,이재혁,권동득 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.5

Purpose: Several study trials have used stem cells to treat stress incontinence in an animal model. In this study, we compared injecting either periurethral mesenchymal stem cells(MSC) or normal saline(C) to increase the leak point pressure(LPP) and closing pressure(CP) in a rat model of stress urinary incontinence. Materials and Methods: Sprague Dawley rats(250g each, 12 weeks old) were divided into the MSC group(n=5) and group C(n=5). They were anesthetized and the pudendal nerve was transected bilaterally via a ventral incision in order to denervate the external urethral sphincter. The MSCs were obtained from both femurs of Sprague Dawley rats(150g each, 6 weeks, n=10). After 1 week, the MSCs were stained by 4'-6-diamidino- 2-phenylindole(DAPI), which was injected into both sites of the proximal external urethra(n=1.5x106). At 3 weeks after injection, cystometry was performed and this was followed by cord transection at the T9-10 level with the rat under anesthesia. Visually identified LPP and CP measurements were evaluated with using a vertical tilt/intravesical pressure clamp. The urethral tissues of the rats were harvested for histology. Results: Both the LPP and CP measurements were significantly higher in the MSC group when compared with that of the C group(p<0.05). The mean LPP of the MSC group and group C was 42.3±2.1cmH2O and 25.8± 1.7cmH2O, respectively. The mean CP of the MSC group and group C was 31.7±2.5cmH2O and 21.3±1.1cmH2O, respectively. The existence of DAPI-stained MSCs in the injected periurethral tissue was verified by histology after the completion of the study. Conclusions: Injection of MSCs into the periurethal tissue after transection of the bilateral pudendal nerve in rats led to an increase in the LPP and CP. This finding suggests that MSCs can be used as one of the potentially effective cell therapies for stress urinary incontinence. (Korean J Urol 2008;49:432-438) Purpose: Several study trials have used stem cells to treat stress incontinence in an animal model. In this study, we compared injecting either periurethral mesenchymal stem cells(MSC) or normal saline(C) to increase the leak point pressure(LPP) and closing pressure(CP) in a rat model of stress urinary incontinence. Materials and Methods: Sprague Dawley rats(250g each, 12 weeks old) were divided into the MSC group(n=5) and group C(n=5). They were anesthetized and the pudendal nerve was transected bilaterally via a ventral incision in order to denervate the external urethral sphincter. The MSCs were obtained from both femurs of Sprague Dawley rats(150g each, 6 weeks, n=10). After 1 week, the MSCs were stained by 4'-6-diamidino- 2-phenylindole(DAPI), which was injected into both sites of the proximal external urethra(n=1.5x106). At 3 weeks after injection, cystometry was performed and this was followed by cord transection at the T9-10 level with the rat under anesthesia. Visually identified LPP and CP measurements were evaluated with using a vertical tilt/intravesical pressure clamp. The urethral tissues of the rats were harvested for histology. Results: Both the LPP and CP measurements were significantly higher in the MSC group when compared with that of the C group(p<0.05). The mean LPP of the MSC group and group C was 42.3±2.1cmH2O and 25.8± 1.7cmH2O, respectively. The mean CP of the MSC group and group C was 31.7±2.5cmH2O and 21.3±1.1cmH2O, respectively. The existence of DAPI-stained MSCs in the injected periurethral tissue was verified by histology after the completion of the study. Conclusions: Injection of MSCs into the periurethal tissue after transection of the bilateral pudendal nerve in rats led to an increase in the LPP and CP. This finding suggests that MSCs can be used as one of the potentially effective cell therapies for stress urinary incontinence. (Korean J Urol 2008;49:432-438)

Polymer Substrate based Electrode Using Modified PVB

김준서,손경철,안다혜,박종진 한국고분자학회 2019 한국고분자학회 학술대회 연구논문 초록집 Vol.44 No.2

심혈관질환 위험인자가 하부요로증상과 발기부전에 미치는 영향

김선옥,손경철,박광성,권동득,류수방,김준석,김희선,임창민 대한남성과학회 2009 The World Journal of Men's Health Vol.27 No.2

Purpose: There are several reports about relationships between cardiovascular risk factors and lower urinary tract symptoms (LUTS). We investigated the effects of risk factors for vascular disease on LUTS and erectile function (ED). Materials and Methods: We prospectively analyzed 273 patients who had LUTS or ED. A self administered questionnaire of International Prostate Symptom Score (IPSS) and International Index of Erectile Function (IIEF) were given to patients. Cardiovascular risk factors including hypertension, smoking status, diabetes and dyslipidemia were determined in each patients. Results: Mean age was 60.5±9.4 years. Mean IPSS, IIEF and IIEF-EF score were 15.9±5.9, 30.1±15.4 and 17.35±9.0, respectively. There are statistically significant differences in the IPSS (p=0.047), IIEF (p=0.024) and IIEF-EF domain score (p=0.044) between men with no risk factors and men with one or more risk factors. IPSS, IIEF and IIEF-EF score were 11.5±6.4, 39.8±11.9 and 19.6±8.7 in men with no risk factor (n=94), 16.6±5.6, 28.4±15.0 and 15.1±9.3 in men with at least one risk factor (n=179). In men with one to four risk factors, the mean IPSS was 14.5±5.1 (n=63), 16.3±4.4 (n=45), 21.2±5.5 (n=43) and 26.5±3.5 (n=28)(p=0.001); the mean IIEF score was 31.4±14.2, 27.8±16.8, 22.5±14.1 and 19.0±9.9 (p=0.037); the mean IIEF-EF score was 17.1±8.9, 14.7±9.0, 10.9±9.7 and 8.8±4.5 (p=0.023), respectively. Conclusions: Men with risk factors for vascular disease are more likely to have a higher IPSS and a lower IIEF and IIEF-EF score than men without risk factors. These results suggests that vascular disease of men is significantly related with the progression of LUTS and ED.

Expression of Plasminogen Activator Inhibitor-2 (PAI-2) During Keratinocyte Differentiation

장선혜,손경철,이경문,윤태진,서영준,김창덕,박장규,이증훈 대한피부과학회 2007 대한피부과학회 학술발표대회집 Vol.59 No.2

염증성 만성골반통증후군 환자에서 항생제 단독요법과 항생제 및 알파차단제 병합요법의 치료효과 비교

윤철웅,손경철,최향식,권동득,박광성,류수방 대한비뇨의학회 2008 Investigative and Clinical Urology Vol.49 No.1

Purpose: The objectives of this study was to compare the efficacy of antibiotic monotherapy with antibiotic plus alpha-blocker combination therapy for the treatment of inflammatory chronic pelvic pain syndrome (CPPS) patients. Materials and Methods: Between October 2005 and May 2006, 69 patients who were diagnosed as CPPS(National Institutes of Health; NIH-catagory IIIa), were included in this study. The patients were randomly placed into two groups: group I was treated with gatifloxacin alone(35 patients), and group II was treated with gatifloxacin and doxazosin(34 patients) for 6 weeks. For all the patients, the urinalysis, expressed prostatic massage, the National Institute of Health-Chronic Prostatitis Symptom Index(NIH- CPSI) and a distal rectal examination(DRE) were performed at the initial visit. The NIH-CPSI was compared both before and after the treatment. Results: On the initial diagnosis, the mean CPSI of the group I patients was 24.0±6.3, and that for the group II patients was 24.7±6.9. After the treatment, that of the group I was 16.6±5.4, and that of group II was 13.4±5.3. After 6 weeks of treatment, the changes in the total CPSI scores had significantly improved in group II compared with group I(p<0.05). A statistically significant improvement occurred in the pain score, the voiding symptom score and the quality of life in the group II compared with group I(p<0.05) Conclusions: This study suggests that combination therapy of antibiotic plus alpha-blocker would be more effective than antibiotic monotheraphy for treating patients with inflammatory chronic prostatitis/chronic pelvic pain syndrome. (Korean J Urol 2008;49:72-76) Purpose: The objectives of this study was to compare the efficacy of antibiotic monotherapy with antibiotic plus alpha-blocker combination therapy for the treatment of inflammatory chronic pelvic pain syndrome (CPPS) patients. Materials and Methods: Between October 2005 and May 2006, 69 patients who were diagnosed as CPPS(National Institutes of Health; NIH-catagory IIIa), were included in this study. The patients were randomly placed into two groups: group I was treated with gatifloxacin alone(35 patients), and group II was treated with gatifloxacin and doxazosin(34 patients) for 6 weeks. For all the patients, the urinalysis, expressed prostatic massage, the National Institute of Health-Chronic Prostatitis Symptom Index(NIH- CPSI) and a distal rectal examination(DRE) were performed at the initial visit. The NIH-CPSI was compared both before and after the treatment. Results: On the initial diagnosis, the mean CPSI of the group I patients was 24.0±6.3, and that for the group II patients was 24.7±6.9. After the treatment, that of the group I was 16.6±5.4, and that of group II was 13.4±5.3. After 6 weeks of treatment, the changes in the total CPSI scores had significantly improved in group II compared with group I(p<0.05). A statistically significant improvement occurred in the pain score, the voiding symptom score and the quality of life in the group II compared with group I(p<0.05) Conclusions: This study suggests that combination therapy of antibiotic plus alpha-blocker would be more effective than antibiotic monotheraphy for treating patients with inflammatory chronic prostatitis/chronic pelvic pain syndrome. (Korean J Urol 2008;49:72-76)

셰일 암반의 강도정수 결정에 관한 연구

이수곤,손경철,김민성,이경수,최호순 대한지질학회 2006 대한지질학회 학술대회 Vol.2006 No.