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RISS 인기검색어
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- 저자 : 성우정 ( Woo Jung Sung ) (검색결과 3 건)
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성우정,최준혁,Sung, Woo-Jung,Choi, Joon-Hyuk The Korean Society for Cytopathology 2007 대한세포병리학회지 Vol.18 No.2
Granular cell tumor is a rare tumor of the soft tissue and this is characterized by proliferation of large cells with granular appearing eosinophilic cytoplasm. We report the imprint cytologic features of a case of granular cell tumor in the left calf of a 52-year-old woman. Microscopic examination showed moderate cellularity. The tumor cells were arranged both as single cells and in clusters. The cells were large polygonal-shaped and they had small round nuclei with finely granular chromatin and occasionally conspicuous nucleoli. The cytoplasm was abundant eosinophilic and granular. Naked nuclei and spindle-shaped tumor cells were occasionally noted. No mitosis and necrosis were present. The background showed cytoplasmic granular materials. The tumor cells showed positivity for S-100 protein. Ultrastructurally, abundant lysosomes were present in the cytoplasm of the tumor cells.
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허혈성 급성 신부전증 실험쥐에 투여한 지방유래 줄기세포의 역할
성우정 ( Woo Jung Sung ),김용진 ( Yong Jin Kim ),박용훈 ( Yong Hoon Park ),김극준 ( Keuk Jun Kim ) 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.5
Purpose: The aim of this study is to explore the role of human adipose tissue-derived adult stem cells (ASCs) in repair of acute ischemic renal injury. Methods: Acute ischemic tubular necrosis was induced in Spraque-Dawley rats (n=15) by clamping bilateral renal pedicles for 40 minutes. Before releasing the clamps, iron labeled stem cells (1×106/0.3 mL) were directly injected to one side of renal cortex and phosphate-buffered saline (PBS) injections were done as a control to the opposite kidney. The examination on both kidney was done after 2 and 4 weeks (n=5 each). The evaluation of the degree of tubular necrosis and the location of stem cells was done by light and electron microscopically. Results: The rats were all alive without rejection. Morphologically, recovery rate was increased up to about 20% in ASCs injection group in 2 weeks-group (p<0.001). Few Prussian-blue positive cells were demonstrated in 2 weeks-group and more cells were present in 4 weeks-group. The cells which were positively stained in Prussian-blue stain were mainly located in peritubular spaces. Electron microscopically, fine iron granules with electron density were found in the cytoplasm of peritubular endothelial cells. Conclusion: As a result, the endothelial cells might be differentiated from injected ASCs. It seems that stem cells help repairing the tubular epithelium in acute renal failure model, not by tubulogenesis but by vasculogenesis. This outcome suggests that the possibility of therapeutic use of ASCs without immunosuppression of recipients in acute ischemic renal injury.
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증례 : 혈액종양 ; 16번 염색체 역위를 가진 급성 골수성 백혈병의 복막 골수성 육종 1예
김지윤 ( Ji Yoon Kim ),박병규 ( Byeong Kyu Park ),배성화 ( Sung Hwa Bae ),류헌모 ( Hun Mo Ryoo ),성우정 ( Woo Jung Sung ),이아진 ( A Jin Lee ) 대한내과학회 2015 대한내과학회지 Vol.89 No.5
골수성 육종(Myeloid sarcoma)은 골수 외를 침범하는 질환으로 급성 골수성 백혈병에서 발생하는 드문 종양이다. inv (16) 염색체 이상을 가진 골수성 육종은 대부분 복강 내에서, 특히 소화관을 침범하는 종괴의 형태로 나타나지만 본 증례에서는 복막의 침윤 및 복수의 형태로 나타나 1예가 있어 보고하는 바이다. Myeloid sarcoma is an extramedullary myeloid neoplasm that usually involves the skin, soft tissues, and lymph nodes. Myeloid sarcoma is found in 2.5-9.1% of acute myeloid leukemia patients, usually those with t (8,21), while inv (16) is rarely associated with myeloid sarcoma. Consequently, little is known of the characteristics and incidence of inv (16) in myeloid sarcoma. Myeloid sarcoma in acute myeloid leukemia patients with inv (16) is most often found in the abdominal lesions, the intestinal tract is involved most commonly, in the form of a mass. Here, we report an unusual myeloid sarcoma presenting as peritoneal carcinomatosis in acute myeloid leukemia with inv (16) that appeared to be ascites. (Korean J Med 2015,89:581-584)
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