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배현우,이소미,김지윤 대한소아혈액종양학회 2017 Clinical Pediatric Hematology-Oncology Vol.24 No.2
We describe our experience regarding metronidazole-induced encephalopathy in a patient with acute lymphoblastic leukemia during chemotherapy. A 17-year-old girl was admitted to our institution with complaints of abdominal pain and mucoid stools. She was diagnosed with acute lymphoblastic leukemia and had been undergoing intensified chemotherapy protocol. During the fifth week of interim maintenance-1 therapy, she developed a fever and complained of chills. On stool examination, stool occult blood was positive and Clostridium difficile toxin A/B test was positive. She was started on metronidazole treatment for possible Clostridium difficile infection and other inflammatory gastrointestinal diseases. Ten days later, the patient complained of dizziness and nausea. A brain MRI was performed to make a differential diagnosis of any chemotherapy-induced CNS complication such as necrotizing leukoencephalopathy. The brain MRI showed features of metronidazole-induced encephalopathy. Metronidazole was discontinued and symptoms started to subside four days after. A follow-up brain MRI performed at four weeks showed that lesions of the dentate nucleus had disappeared.
Treatment Outcomes of Brain metastasis from Papillary Thyroid Cancer
배현우,김석모,김수영,장호진,김법우,이용상,장항석,박정수,Bae, Hyeonwoo,Kim, Seok-Mo,Kim, Soo Young,Chang, Ho Jin,Kim, Bup-Woo,Lee, Yong Sang,Chang, Hang-Seok,Park, Cheong Soo The Korean Society for Head and Neck Oncology 2018 대한두경부 종양학회지 Vol.34 No.1
Background/Objectives: Brain metastasis (BM) is a rare form of distant metastasis with papillary thyroid cancer (PTC). Patients with BM of PTC carry a poor prognosis. The aim of this study was to contribute to the understanding of this disease by analyzing patients with BM of PTC. Materials & Methods: Between March 2003 and December 2013, the patient database was conducted to identify thyroid cancer patients treated. Among the 22,758 thyroid cancer patients, 14 (0.06 %) were identified to have metastasis to the brain during follow-up. The medical records of 14 patients with BM were retrospectively reviewed, focusing on the following: patient characteristics, synchronous or previous distant metastasis, treatments including whole brain radiotherapy (WBRT), stereotactic radiosurgery (SRS) and surgery, and characteristics on radiologic findings, time interval between first diagnosis of primary thyroid cancer and BM and survival after BM. Results: The mean age at initial diagnosis and BM were $50.9{\pm}15.8years$ and $61.3{\pm}12.7years$. The mean duration between initial diagnosis and BM was $10.4{\pm}7.9years$. Patients were treated with varied combinations of surgery, SRS and WBRT except 4 patients who had refused treatment. The median overall survival (OS) time after BM diagnosis was 10 months (range 1 - 19). Patients receiving treatment (WBRT and/or surgery, SRS) had a significant longer median OS of 16.5 months in comparison to 3.5 months for those treated without treatment. (p = 0.005) Conclusion: Patients who received aggressive treatment had a longer OS than those with only supportive care. Treatment such as surgery, SRS and WBRT should be considered in patients with BM.
자흡식 벤츄리 노즐에서의 물-공기 이상유동의 특성에 대한 실험적 연구
배현우,유인수,성재용,이명호 한국생산제조학회 2019 한국생산제조학회지 Vol.28 No.6
Self-entrainment of air occurs when water is supplied through a venturi nozzle with an air hole in its throat. To study the characteristics of air entrainment, the air flow rates and air volume ratio were measured. The flow inside the nozzle was visualized for various diverging angles and water flow rates. The results shows that air entrainment increases with the water flow rate; however, the air volume ratio remains almost constant. Furthermore, air entrainment is the highest at a diverging angle of 40°. As the water flows downstream, an annular, two-phase flow starts to form in the diverging section, changing the flow pattern to a churn flow. This sudden expansion in the diverging section induces a vortex separation that blocks the pathway of air entrainment when air bubbles are present in the vortex.
배현우,도기덕,김인호,장성열 한국해양공학회 2022 韓國海洋工學會誌 Vol.36 No.4
The process-based XBeach model has numerous empirical parameters because of insufficient understanding of hydrodynamics and sediment transport on the nearshore; hence, it is necessary to calibrate parameters to apply to various study areas and wave conditions. Therefore, the calibration process of parameters is essential for the improvement of model performance. Generally, the trial-and-error method is widely used; however, this method is passive and limited to various and comprehensive parameter ranges. In this study, the Generalized Likelihood Uncertainty Estimation (GLUE) method was used to estimate the optimal range of three parameters (gamma, facua, and gamma2) using morphological field data collected in Maengbang beach during the four typhoons that struck from September to October 2019. The model performance and optimal range of empirical parameters were evaluated using Brier Skill Score (BSS) along with the baseline profiles, sensitivity, and likelihood density analysis of BSS in the GLUE tools. Accordingly, the optimal parameter combinations were derived when facua was less than 0.15 and simulated well the shifting shape, from crescentic sand bar to alongshore uniform sand bars in the surf zone of Maengbang beach after storm impact. However, the erosion and accretion patterns nearby in the surf zone and shoreline remain challenges in the XBeach model.
학술논문7 : G2 시대 중국의 동아시아 안보전략에 관한 연구 -공격적 현실주의 관점으로 조망한 중국의 동아시아 패권전락을 중심으로-
배현우 ( Hyun Woo Bae ) 한국군사학회 2014 군사논단 Vol.78 No.-
This study is presenting the directions of future for Republic of Korea which is evaluated as a muddle state due to relatively strong surrounding powers by taking a view of Hegemony Strategy of China in East Asia with a realistic view of Mearsheimer within East Asia order which is turning a new view now. A new type of great-power relationship is that China advocates is a highly difficult respond to “Strategy of rebalancing toward asia” of the United states, including the internal commitment for not adapting to the existing orders lead by the United states. The United States trying to the policy conversion as a “less activist foreign policy” for divisions of roles by Alliance & Friendly nations in order to push forward with the “Strategy of Blockade & Hedging” of Military & Securitive Side to China based on the U.S.-Japan alliances. China is seeking a strategy for securing the Maritime controls in order to expand their influences by overcoming restraint from the United States in Asia Pacific Area. Also, proclamation of East China Sea ADIZ(Air Defense Identification Zone) Was promoted within such contexts. The Peace Policy China has advocated is not a policy that seeks for peace essentially, but a Temporary & potential phenomenon that watch for an opportunity to change to pursuit of supremacy powers at any time. Progresses of China have been occurred in Northeast Asia recently has shown aspects of oriented Hegemony which overthrows the existing situation and expands by maximizing powers.