http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
제2형 당뇨병 환자에서 심혈관계 자율신경병증과 상완-발목 맥파속도의 상관 관계
배영필,이병도,김봉건,박종화,권용섭,박자영,이창원,김보현,장재식 대한내분비학회 2011 Endocrinology and metabolism Vol.26 No.1
Background: Cardiovascular disease is the leading cause of death in patients with type 2 diabetes. Clinically, evaluating cardiovascular autonomic neuropathy (CAN) is important to predict cardiovascular mortality because it is correlated with cardiovascular death. The pulse wave velocity (PWV) correlates well with arterial distensibility and stiffness. It is also a useful approach for evaluating the severity of systemic atherosclerosis in adults. So, we evaluated that the relationship between cardiac autonomic neuropathy and the brachial-ankle pulse wave velocity (baPWV) in patients with type 2 diabetes. Methods: We retrospectively analyzed 465 patients (209 men and 256 women) with type 2 diabetes. We checked the clinical characteristics and the laboratory tests and we assessed the diabetic complications. Standard tests for CAN were performed by DiCAN (Medicore, Seoul, Korea): 1) heart rate variability during deep breathing (the E/I ratio), 2) a Valsalva maneuver, 3) 30:15 ratio of R-R interval the blood pressure response to standing, and 5) the blood pressure response to handgrip. The CAN score was determined according to the results of the test as following: 0 = normal, 0.5 = borderline, 1 = abnormal. We also measured the baPWV by using a VP 1000 (Colin, Japan) and all the analyses were performed with the SPSS version 14.0. P values < 0.05 were considered significant. Results: The CAN score is associated with the maximal baPWV, age, systolic blood pressure, microalbuminuria, the duration of diabetes,angiotensin II receptor blocker treatment, calcium channel blocker treatment, β-blocker treatment and nephropathy. After adjusting for age, the baPWV is a independent predictor of the risk for CAN (β = 0.108, P = 0.021). Conclusion: The CAN is associated with the baPWV in patient with type 2 diabetes.
이병도,배영필,김봉건,박종화,김동현,박자영,최성호,박희승,이재승,이창원,김상수,김보현,최문기,김인주 대한내분비학회 2011 Endocrinology and metabolism Vol.26 No.2
Background: There is a close connection between type 2 diabetes mellitus and the risk of cancers and related mortality. The principal objective of the present study was to explore the association between type 2 diabetes and colorectal cancer. Methods: We retrospectively compared 1111 subjects (age ≥ 30 years) who were subjected to colonoscopies between June 2006 and June 2009. We evaluated the anthropometric data, presenting symptoms and signs, history of diabetes, laboratory data, colonoscopy findings and biopsy results. We analyzed the correlation between colorectal cancer and influencing factors, and compared the incidence rates of colorectal cancer in the type 2 diabetes and control groups. Results: Four hundreds and seven of the subjects had diabetes mellitus. The incidence of colorectal cancer was increased significantly in type 2 diabetes relative to the control group (7.4% vs. 3.4%, P < 0.05). Colorectal cancer was correlated significantly with age, type 2 diabetes, constipation, anemia, and gastrointestinal symptoms. Following logistic regression analysis, age and constipation were associated significantly with colorectal cancer. In the age below 65 years subgroup, the incidence of colorectal cancer was increased significantly in the type 2 diabetes group relative to the control group. Conclusion: Type 2 diabetes was associated with increased colorectal cancer risk. This association was more definite in the subjects younger than 65 years.
A Case of Postcardiac Injury Syndrome Presenting as Acute Mediastinitis
임홍규,배영필,이병두,김봉건,박종화,김분형,장재식 대한심장학회 2009 Korean Circulation Journal Vol.39 No.7
A 41-year-old man sought evaluation at the emergency department for pain in the anterior chest that had been ongoing for approximately 35 hours. The electrocardiogram showed marked ST segment elevation in the precordial leads. Cardiac biomarker levels were elevated. He subsequently underwent coronary angioplasty and stenting of the left anterior descending artery using two sirolimus-eluting stents. The following day, the patient complained of severe pain in his chest and shoulders. Computed tomography (CT) of the chest showed small gas bubbles around the aortic wall and mild pericardial thickening with subtle air densities, suggesting acute mediastinitis. With an impression of postcardiac injury syndrome and acute mediastinitis, he was treated with intravenous antibiotics and oral ibuprofen. Two days later, the patient had subjective improvement and the friction rub was no longer heard. A 41-year-old man sought evaluation at the emergency department for pain in the anterior chest that had been ongoing for approximately 35 hours. The electrocardiogram showed marked ST segment elevation in the precordial leads. Cardiac biomarker levels were elevated. He subsequently underwent coronary angioplasty and stenting of the left anterior descending artery using two sirolimus-eluting stents. The following day, the patient complained of severe pain in his chest and shoulders. Computed tomography (CT) of the chest showed small gas bubbles around the aortic wall and mild pericardial thickening with subtle air densities, suggesting acute mediastinitis. With an impression of postcardiac injury syndrome and acute mediastinitis, he was treated with intravenous antibiotics and oral ibuprofen. Two days later, the patient had subjective improvement and the friction rub was no longer heard.
정진도,김장우,배영필,Chung, Jin-Do,Kim, Jang-Woo,Bae, Young-Peel 대한환경공학회 2010 대한환경공학회지 Vol.32 No.1
본 연구의 목적은 대형 석탄 화력 발전소에 DSI (Dry Sorbent Injection)공정을 실제 적용 할 경우에 실현 가능성에 대한 연구로서 N 발전(주)의 S 화력발전본부에서 운용중인 500MW급 석탄화력 발전시설의 보일러 후단에서 전기 집진기 전 단까지를 모델로 삼아 Lab-scale 실험장치를 제작하여 탈황효율을 높이기 위한 실험을 수행하였다. 이를 위하여 Lobedplate와 Step-plate라는 혼합촉진장치를 고안하고 각각 형상을 달리하여 궁극적으로 탈황효율을 높이기 위한 혼합촉진장치의 최적 형상도출을 위한 실험을 수행하였으며 부수적으로 탈황제의 분사구의 개수에 따른 탈황효율 또한 분석하였다. 그 결과 혼합촉진장치가 설치된 경우가 더 높은 탈황 효율을 나타내었고 형상에서는 계단형상일 경우 가장 높은 탈황효율을 보였다. 또한, 탈황제의 분사구의 개수에 따른 탈황효율은 혼합 촉진 장치가 설치되지 않은 경우, 분사구의 개수가 증가할수록 높은 탈황 효율을 보였으나 혼합촉진장치가 설치된 경우는 분사구의 개수가 4개일 경우가 이론적 결과와 같이 가장 높은 탈황효율을 나타내었다. The aim of this study is to research applicable possibility of DSI (Dry Sorbent Injection) technique in $SO_2$ removal process using lab-scale facility based on 500MW in capacity coal-fired thermal power plant operated by South Korea N. Power Co., Ltd. To increase the $SO_2$ removal efficiency, it is considered the mixing enhancement as different shapes called lobed-plate and stepplate tested ultimately for optimum shape. Also it tested to analysis $SO_2$ removal efficiency by numbers of injection holes. At experimental it showed the $SO_2$ removal efficiency is higher using mixing enhancement than not installed mixing enhancement and case on the step-plate was shown the most $SO_2$ removal efficiency. Also, $SO_2$ removal efficiency was higher recording which will increase the injection holes case on not installed mixing enhancement. But, the $SO_2$ removal efficiency was higher 4 injection holes case on installed mixing enhancement.