목재와 목질판상의 Dowel-Joint 판강접합 특성에 관한 비교분석

박희준,이필우(Hee Jun Park),Phil Woo Lee 한국가구학회 1990 한국가구학회지 Vol.1 No.1

The dewel joint is one of the most widely used joint types in modern woodworking, especially in wooden furniture manufacturing.<br/> L-type specimens of two solid woods(Antiaris, Sepetir) and three wood based materials (Plywood, Particleboard, and Medium Density Fiberboard), 15mm thick, 100mm wide, and 150mm long in size, were constructed with 1, 2, 3 and 4 dowels of 6, 8, and 10mm diameter by polyvinyl acetate resin adhesive in this study. Stiffness coefficient and strength of the L-type specimens were determined by the aid of universal testing machine.<br/> The stiffness coefficients of the specimens constructed with one dowel was in the 10^-3 level, indicative of flexible joints but those with 2, 3, 4 dowels were in the 10^-4 level, indicative of relatively stable joint. The 8mm dowel was superior to 6 and 10mm dowels in bending strength, and the bending strength increased with the increase of dowel number from 1 to 4, however, the increasing rate of bending strength from 1 to 2 dowels was higher than from 3 to 4 dowels.<br/> The most superior joints strength was obtained in constructions with 4 dowels of 8mm diameter for wood based materials (Plywood, particleboard and Medium Density Fiberboard) and with 4 dowels of 10mm diameter for solid wood(Antiaris and Sepetir), respectively.

NH₃ Plasma Treatment를 사용한 고성능 TFT 제작 및 분석

박희준,이준신,Park, Heejun,Nguyen, Van Duy,Yi, Junsin 한국전기전자재료학회 2017 전기전자재료학회논문지 Vol.30 No.8

The effect of $NH_3$ plasma treatment on device characteristics was confirmed for an optimized thin film transistor of poly-Si formed by ELA. When C-V curve was checked for MIS (metal-insulator-silicon), Dit of $NH_3$ plasma treated and MIS was $2.7{\times}10^{10}cm^{-2}eV^{-1}$. Also in the TFT device case, it was decreased to the sub-threshold slope of 0.5 V/decade, 1.9 V of threshold voltage and improved in $26cm^2V^{-1}S^{-1}$ of mobility. Si-N and Si-H bonding reduced dangling bonding to each interface. When gate bias stress was applied, the threshold voltage's shift value of $NH_3$ plasma treated device was 0.58 V for 1,000s, 1.14 V for 3,600s, 1.12 V for 7,200s. As we observe from this quality, electrical stability was also improved and $NH_3$ plasma treatment was considered effective for passivation.

음나무 잎 및 수피의 진통소염효과 및 아주반트로 유발된 산화적 스트레스에 대한 효과

박희준,남정환,정현주,김원배,박광균,정원윤,최종원,Park, Hee-Juhn,Nam, Jung-Hwan,Jung, Hyun-Ju,Kim, Won-Bae,Park, Kwang-Kyun,Chung, Won-Yoon,Choi, Jong-Won 한국생약학회 2005 생약학회지 Vol.36 No.4

The leaves (KPL) of Kalopanax pictus (KP) are used as a vegetable or a functional food in Korean society. The stem bark (Kalopanacis Cortex, KPS) has been traditionally used to treat neurotic pain, rheumatoid arthritis and diabetic disease. This research was undertaken to demonstrate that the leaf extract of KP (KPL) has also the antinociceptive and antiinflammatory effects like the extract (KPS) of Kalopanacis Cortex and to compare the activity levels of several extracts obtained from KP. Antinociceptive and antiinflammatory effects were measured against the extracts described as followings; KPL-1 (the MeOH extract obtained from the leaf shoot of KP collected on May), KPL-2 (the MeOH extract from KP collected on June), KPL-3 (the MeOH ectract from KP with no thorns), KPS-1 (MeOH extract from KPS of a Korean habitat), KPS-2 (MeOH extract from KPS of a Chinese habitat). The antimociceptive test undertaken by acetic acid-induced writhing, hot plate-, and tail-flick methods using mice. The anti-inflammatory test was also undertaken by measuring the edema in the carrageenan-induced test. The order of activity potency in the antinociceptive and antiinflammatory assays was commonly shown as followings: KPL-3>KPS>1>KPS-2>KPL-1>KPL-2. This order was also observed in acetic acid-induced vascular permeability test. The antiinflammatory activity in carrageenan-induced assay was also observed as the following order: KPL-3>KPS- 1>PS-2>KPL-1>KPL-2. In addition, adjuvant-induced rats were used for a model to assess the oxidative stress. Treatment of the rat with the extracts reduced serum thiobarbituric acid-reactive substances (TBARS), hydroxy radical(OH) and superoxide dismutase(SOD) activity caused by FCA together together with the inhibition of hepatic TBARS level and lipofuscin content. The above finding suggests that the leaf extract has the antinociceptive and antinflammatory activity. It is also suggested that KPL-3 with more potent activity than other tested extracts could be developed for a new available biomaterial.

Effect of Kaikasaponin III Obtained from Pueraria thunbergiana Flowers on Serum and Hepatic Lipid Peroxides and Tissue Factor Activity in the Streptozotocin-Induced Diabetic Rat

박희준,Myung-Hee Shin,Kun-Young Park,Kyung-Tae Lee,Hyun-Ju Jung,Myung-Sun Lee,Jongwon Choi 한국식품영양과학회 2004 Journal of medicinal food Vol.7 No.1

We investigated the effect of kaikasaponin III (KS-III) on Phase I and II enzymes and tissue factor (TF) activity to elucidate the pharmacological actions of the immunosuppressive saponin, kaikasaponin III, in the diabetic rat. This compound was obtained from the flower of Pueraria thumbergiana (Leguminosae) by chromatographic isolation. This crude drug (Puerariae Flos) has been used as a therapeutic agent for diabetes mellitus in traditional Korean medicine. KS-III prolonged the bleeding time and plasma clotting time in the streptozotocin (STZ)-treated rats and increased the TF activity, suggesting that this compound has anti-thrombosis activity in STZ-induced rats. It also inhibited the formation of malondialdehyde (MDA) and hydroxy radicals in serum and liver, but promoted superoxide dismutase (SOD) activity. Low MDA concentrations and low xanthine oxidase and aldehyde oxidase activities were observed in the KS-III -treated rats, suggesting that such Phase I enzyme activities are the major source of lipid peroxidation. However, KS-III increased Phase II enzyme activities such as SOD, glutathione peroxidase and catalase, suggesting the activation of free radical-scavenging enzymes. These results suggest that KS-III may exhibit its hypoglycemic and hypolipidemic effects by upregulating or downregulating antioxidant mechanisms via the changes in Phase I and II enzyme activities.

In Vivo Antihepatotoxic Effects of Ligularia fischeri var. spiciformis and the Identification of the Active Component, 3,4-Dicaffeoylquinic Acid

박희준,Jongwon Choi,Jung-Kwan Park,Kyung-Tae Lee,박광균,Won-Bae Kim,Jin-Ha Lee,정현주 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.3

Pretreatment with a methanolic extract of Ligularia fischerivar. spiciformis(Compositae) herb inhibited he-patotoxicities caused by CCl4, D-galactosamine (GalN), .-naphthylisothiocyanate (ANIT), and DL-ethionine in rats. An ethylacetate (EtOAc) extract fractionated from the methanolic extract showed a strong inhibitory effect. A major component, 3,4-dicaffeoylquinic acid (DCQA), isolated from the methanolic extract was examined for antihepatotoxicity. Pretreatment withDCQA (5 and 10 mg/kg, p.o.) significantly reduced serum aminotransferases (alanine and aspartate), sorbitol dehydrogenase,.-glutamyltransferase, alkaline phosphatase, and lactate dehydrogenase activities during CCl4- or GalN-induced hepatotoxic-ity, suggesting that DCQA is a major principle for the antihepatotoxic activity of L. fischerivar. spiciformis. DCQA also par-tially restored bile flow and reduced total bilirubin and cholic acid concentrations in rats with ANIT-induced cholestasis. Treat-ment with DCQA inhibited the increase in triglyceride, cholesterol, and total lipids in DL-ethionine-induced fatty liver. Theseresults support the traditionally held belief that this plant can be used for the treatment of jaundice and hepatic failure.

대두와 돌콩의 항산화 활성 및 성분비교

박희준,이은,최무영,임태진,차배천,Park, Hee-Juhn,Lee, Eun,Choe, Moo-Young,Rhim, Tae-Jin,Cha, Bae-Cheon 한국생약학회 1996 생약학회지 Vol.27 No.3

Wildbean(Glycine soja Siebold et Zucc.) is known as the orgin of soybean (Glycine max Merr.). Based on the hypothesis that the secondary transformation of chemical compound in wildbean might have occurred during its breed improvement to soybean. this study was carried out to compare the antioxidant activities and chemical composition in wildbean and soybean. The present study demonstrates that 1) Antioxidant activity was much higher in EtOAc, extract of wildbean than in soybean. 2) strong antioxidant activity observed in EtOAc extract of wildbean was due to the presence of (-)-epicatechin, which was not present in the extract of soybean but isolated, for the first time, from the extract of wild bean, and 3) antioxidant activity of the isolated (-)-epicatechin was greater than that of tocopherol, the previously known antioxidant.

함박꽃나무 잎으로 부터 새로운 Aporphine계 Alkaloid 성분의 분리

박희준,Park, Hee-Juhn 한국생약학회 1996 생약학회지 Vol.27 No.2

From the leaves of Magnolia sieboldii a new aporphine-type alkaloid named magnoporphine was isolated. The structure of magnoporphine was all assigned by $^1H-^1H$COSY, $^1H-^{13}C$ COSY and $^1H-^{13}C$ long range NMR. In addition, costunolide, syringin, syringenin $4-O-{\beta}-cellobioside$ and echinacoside was isolated.

The Comparison of Behavioral Response of Additional Submucosal Midazolam with Oral Chloral Hydrate, Hydroxyzine and Nitrous Oxide for Pediatric Conscious Sedation

박희준,정상혁,백광우,Park, Hui-Jun,Jung, Sang-Hyuk,Baek, Kwang-Woo The Korean Dental Society of Anesthsiology 2007 Journal of Dental Anesthesia and Pain Medicine Vol.7 No.1

배경: 소아 진정 치료 시 서로 다른 용량의 chloral hydrate와 hydroxyzine을 복용 후 midazolam을 구강 점막 하 주사했을 때 행동 반응을 비교하였다. 방법: 총 32회 진정법을 통해 치과치료를 받은 30명의 나이 24-72개월, 체중 20 kg 미만의 미국 마취과학회 신체등급 I의 건강하지만 겁이 많고 협조가 안 되는 소아 환자를 대상으로 2개 치아이상의 보존 치료 및 발치를 필요로 하는 환자를 대상으로 하였다. 호흡기 질환이 있는 아이들은 이 연구에서 제외되었다. 연구 계획은 이대 목동 병원의 임상 실험 심사 위원회에 제출되었다. 1군은 chloral hydrate 50 mg/kg와 hydroxyzine 1 mg/kg 복용 후 점막 하 midazolam 0.2 mg/kg을 추가 투여했고 2군은 chloral hydrate 60 mg/kg와 hydroxyzine 1 mg/kg 복용 후 점막 하 midazolam 0.1 mg/kg을 주사 받았다. 50% nitrous oxide는 치료 중 두 군 모두 유지되었다. 전날 수면 시간과 약물 복용 태도를 기록하였으며 모든 치료 과정은 비디오로 촬영되었다. 맥박 산소 계측기를 이용하여 경피적 산소 포화도와 맥박수를 기록하였고 행동 반응은 Houpt scale을 이용하여 매 2분마다 40분 동안 기록되었다. 전반적인 행동 반응은 Houpt scale를 이용하여 평가되었다. 모든 자료는 SPSS 통계 프로그램을 이용하여 two sample independent t-test를 사용하였다. P 값은 0.05 미만인 경우를 통계학적으로 유의하다고 보았다. 결과: 두 군 간의 경피적 산소 포화도와 맥박수는 모두 정상 범위이며 유의한 차이가 없었다. 행동 반응 비교에서는 치료 처음 10분 동안 2군이 1군에 비해 점수가 높게 나왔으며(P < 0.05), 그 외에는 유의한 차이가 없었다. 전날 총 수면 시간과 약물을 복용하는 태도는 수면 치료 중의 행동 반응에 영향을 주지 않았다. 결론: Chloral hydrate 50 mg/kg 복용과 점막 하 midazolam 0.2 mg/kg은 chloral hydrate 60 mg/kg 복용과 점막 하 midazolam 0.1 mg/kg과 비교할 때 두 약물의 조합은 모두 소아 환자 수면 치료시 안전하고 효과적인 용량이다. Overall behavior와 Q (quiet)의 분포를 비교해 볼 때 두 군 모두 성공적인 진정효과를 기대할 수 있다.

진흥법 개정 이후의 방향과 과제

박희준,Park, Hui-Jun 한국전자정보통신산업진흥회 1981 電子振興 Vol.1 No.4

Antihepatotoxic effect of Heat-treated Allium victorialis var. platyphyllum in CCl4-induced Rats and the Gas Chromatographic Analysis of Volatile Sulfur Substances

박희준,Hyun-Ju Jung,Sang-Cheol Lim,Won-Tae Jung,Won-Bae Kim,Kwang-Kyun Park,Jin-Ha Lee,Jong-Won Choi 한국생약학회 2005 Natural Product Sciences Vol.11 No.2