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갑상샘의 소포샘종과 소포암종의 세포 소견: 세침흡인 세포 진단의 가능성에 대한 연구
박희대,박운선,김선희,최석현,조영혜,강성희,이경분,김민경,김동훈,채승완,손진희,Park, Hee-Dae,Park, Woon-Sun,Kim, Sun-Hee,Choi, Seock-Hyun,Cho, Young-Hye,Kang, Sung-Hee,Lee, Kyung-Bun,Kim, Min-Gyeong,Kim, Dong-Hoon,Chae, Seoung-Wan,Shon 대한세포병리학회 2008 대한세포병리학회지 Vol.19 No.2
Fine-needle aspiration cytology (FNAC) cannot differentiate follicular adenoma from follicular carcinoma since this distinction can only be based on the presence of capsular or vascular invasion, and this can¬not be detected on a cytologic smear. The goal of this study was to define the diagnostic cytologic findings of follicular neoplasm and the possibility of diagnosing follicular neoplasm by performing FNAC. The cases of histologically diagnosed follicular adenoma and follicular carcinoma on the thyroidectomy specimens were retrieved. Among them, the cases with preoperative FNAC that was done within 3 months of the operation were finally selected. Then we reviewed the FNAC and histologic slides of 19 cases: 9 follicular adenomas and 10 follicular carcinomas. Our results suggest that for cases of follicular neoplasm, the aspirates show high or abundant cellularity, frequent follicle formation and occasional cellular atypism of the follicular cells. However, the atypism is more pronounced and more frequently noticed in the cases of follicular carcinoma, which reveals more higher anisocytosis (7/10, 70%), nuclear pleomorphism (9/10, 90%), coarse clumping of chromatin (8/10, 80%) and cellular overlapping (8/10, 80%).
마그네슘 합금의 공정 변수제어에 따른 결정립크기와 기계적 성질 연관 분석
박희대(Hee-Dae Park),강성훈(Seong-Hoon Kang),이정환(Jung-Hwan Lee) 한국기계가공학회 2007 한국기계가공학회 춘추계학술대회 논문집 Vol.2007 No.-
This work was focused on the grain refinement of magnesium alloys AZ31 and ZK60 using equal channel angular pressing (ECAP) in order to enhance the mechanical properties such as the strength, elongation and hardness. In ECAP experiments, the effect of processing temperature and number of pass on the grain refinement was investigated. It was found out that the processing temperature has a significant influence on the grain refinement than the number of pass. It was experimentally observed that the average grain size (223㎛) of as-cast AZ31 was reduced up to 3μm after ECAP using 400℃/4 passes and successive 250℃/5 pass. On the other hand, as-cast ZK60 with grain size of 96 μm was refined up to 2.4 μm after ECAP using 250℃/ 8 passes. Also, to check the improvement in mechanical properties of ECAPed AZ31 and ZK60, the tensile tests were performed according to the various temperature and strain rate. It was generally observed from the tensile testing that the tensile and yield strengths decrease with decreasing grain size. However, elongation and micro-hardness tends to increase with reduction of grain size.
차단막 형성과 전해질의 최적화에 의한 광전변환 효율 개선 연구
박희대(Hee-Dae Park),주봉현(Bong-Hyun Joo),성열문(Youl-Moon Sung) 한국조명·전기설비학회 2013 조명·전기설비학회논문지 Vol.27 No.3
In this work, the effects of blocking layer and optimally fabricated electrolyte were investigated with respect to impedance and conversion efficiency of the cells.A layer of TiO<SUB>2</SUB> less than ∼200nm in thickness, as a blocking layer, was deposited by rf sputtering onto the F:SnO<SUB>2</SUB> (FTO) glass to be isolated from the electrolyte in dye-sensitized solar cells (DSCs). Also, optimum condition of electrolytes preparation for DSCs was investigated. 3-methoxyppropionitrie and redox pairs with LiI and I<SUB>2</SUB> were used as solvents for fabrication of electrolyte. The electrochemical impedances of DSCs using this photo-anode were R<SUB>1</SUB>: 13.8, R<SUB>2</SUB>: 15.1, R<SUB>3</SUB>: 11.9 and R<SUB>h</SUB>: 8.3Ω, respectively. The R<SUB>2</SUB> impedance related by electron transportation from porous TiO<SUB>2</SUB> to FTO showed lower than that of normal DSCs. The photo-conversion efficiency of prepared DSCs was 6.4% and approximately 1.3% higher than general one.
LiF ( Mg , Cu , Na , Si ) 열형광선량계에 의한 베타선량 측정
도시홍,박희대,김도성,강희동 ( Sih Hong Doh,Hee Dae Park,Do Sung Kim,Hee Dong kang ) 한국센서학회 1993 센서학회지 Vol.2 No.2
LiF(Mg, Cu, Na, Si)TLD was prepared by sintering LiF doped with Mg, Cu, Na, and Si, and an extrapolation ionization chamber was fabricated to measure the absorbed dose of β rays. The detection efficiency, individual dose equivalent(superficial)Hy(0.07), depth-dose curve, and energy compensation filter were investigated in the range from 200 keV tcn 2:279 MeV of β ray energies. The TL response was also tested as a function of the grain size in the range of 44∼250 ㎛.
조은윤,박희대,김선희,박운선,채승완,김어진,손진희,Cho, Eun-Yoon,Park, Hee-Dae,Kim, Sun-Hee,Park, Woon-Sun,Chae, Seoung-Wan,Kim, Eo-Jin,Sohn, Jin-Hee 대한세포병리학회 2004 대한세포병리학회지 Vol.15 No.2
To analyze the accuracy and usefulness of sputum cytology as a screening method, 103 cases of histologically proven lung cancer registered from 1998 to 2000 at Kangbuk Samsung Hospital were retrospectively examined. We reviewed the original cytologic and surgical diagnoses for the cases, and the cytology slides of all cytologically negative cases. The overall sensitivity of sputum cytology was 0.83 ; the sensitivity of prebronchoscopy sputum cytology for bronchogenic carcinoma was 0.87. Central tumor location (P=0.002), tumor size (>2.4 cm), (P=0.027) and the number of sputum samples $(\geq3)$ (P=0.001) were associated with a positive cytologic diagnosis. Of the 18 cytologically negative cases, 9 cases(38% of smears) were determined to be insufficient for diagnosis, due strictly to low cellularity and saliva. After a review of the cytology slides of cytologically negative cases, we identified several atypical clusters in one case of bronchioloalveolar carcinoma. This negativity was thus attributed to an interpretation error (1/18, 5.6%). Our results suggest that its sensitivity is more strongly related to the specimen adequacy and the times of sampling than to interpretation error. In terms of sensitivity, specificity, accessibility, cost, and morbidity associated with the screening tests, sputum cytology was found to be an accurate effective screening method for lung cancer.