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      • Bee Pollen 섭취 후 발생한 아나필락시스

        한정 ( Han Jung Park ),허규영 ( Gyu Young Hur ),김현아 ( Hyun Ah Kim ),예영민 ( Young Min Ye ),서창희 ( Chang Hee Suh ),남동호 ( Dong Ho Nahm ),해심 ( Hae Sim Park ) 대한천식알레르기학회 2007 천식 및 알레르기 Vol.27 No.1

        We report a case of a 54-year-old woman with atopy who showed a severe anaphylactic reaction after the ingestion of bee pollens. A few minutes after the ingestion, generalized pruritus, urticaria, periorbital and perioral angioedema, and dyspnea developed, and thus the emergency care including subcutaneous epinephrine and intravenous methylprednisolone was performed. She suffered from seasonal allergic rhinitis for 10 years. Microscopic examination of the bee pollen ingested showed mostly mugwort and ragweed pollen, and several kinds of tree pollens. In vivo and in vitro studies demonstrated that the patient had allergic rhinitis sensitive to mugwort and ragweed pollens and sensitized to some tree pollens as well. This case demonstrated that a severe systemic allergic reaction could occur in a pollen-sensitized patient after the ingestion of bee pollens. (Korean J Asthma Allergy Clin Immunol 2007;27:57-60)

      • SCOPUS
      • 혈액투석 중에 발생한 헤파린에 의한 전신 두드러기

        한정 ( Han Jung Park ),성준모 ( Jun Mo Sung ),김무정 ( Moo Jung Kim ),최길순 ( Gil Soon Choi ),예영민 ( Young Min Ye ),해심 ( Hae Sim Park ) 대한천식알레르기학회 2009 천식 및 알레르기 Vol.29 No.1

        Heparin is used for thromboprophylaxis in patients on hemodialysis, hemofiltration or continuous renal replacement therapies. Heparin-related immediate-type hypersensitivity reactions such as urticaria, angioedema or bronchospasm are very rare, and only a few cases of anaphylaxis-like responses have been described. We experienced the case of a 67-year-old female patient with an end-stage renal disease who presented generalized urticaria induced by heparin during hemodialysis. She began to experience recurrent itching and generalized urticaria after 2 weeks of the initiation of hemodialysis. The episodes started within 30 minutes of hemodialysis with heparin infusion; either sodium heparin or dalteparin (low molecular weight heparin) was used. Utilization of different dialyzers was unable to avoid the episodes, and these symptoms could be reduced when she was treated with heparin-free hemodialysis. She had no previous history of allergic diseases. In order to confirm the causative agent, we measured serum specific IgE antibodies against ethylene oxide, latex and formaldehyde using immunoCAP (Phadia, Sweden) and obtained negative results. Although skin prick tests and intradermal tests to the used heparin showed negative results, the intravenous provocation test using 1,500 U of heparin (with a bolus-loading dose of 1,000 U and a continuous intravenous infusion of 500 U for 3 hours) reproduced an immediate-onset generalized urticaria with itching sensation. We report herein a case of heparin-induced urticaria during hemodialysis in Korea. Because of increasing use of heparin in medical practice, physicians should be aware of possible immediate hypersensitivity reactions to this medication. (Korean J Asthma Allergy Clin Immunol 2009;29:69-73)

      • SCOPUS

        한국 의과대학의 행동과학 강좌 개설 실태조사 및 표준 교수요목 개발

        박정한(Jung Han Park),이주영(Ju Young Lee),강복수(Pock Soo Kang) 한국의학교육학회 1999 Korean journal of medical education Vol.11 No.2

        우리 나라 의과대학의 행동과학 교육실태를 파악하고, 바람직한 학습목표와 교수요목을 개발하기 위하여 1996년 1월 전국 32개 의과대학의 행동과학과목 담당 책임교수를 대상으로 행동과학 교육 실태를 조사하고, Delphi기법으로 바람직한 학습목표와 교수요목을 개발하였다. 1차 설문조사에서는 32개 의과대학 중 27개 의과대학의 담당교수가 응답하였고, 2차 조사에 23명, 3차 조사에 19명이 응답하였다. 의과대학에서의 행동과학 학습목표는 인간의 행동을 생물학적, 심리학적, 사회․문화적 측면에 대한 이해, 신체와 정신의 관계 (스트레스와 질병) 이해, 의사와 환자 관계 형성 기법 습득, 환자에 대한 전인적인 접근에 관한 지식과 기술 습득 등의 내용을 포함하는 것이 타당하다. 기본적인 교수요목으로는 의학과 행동과학 (행동의 기본 원리), 신체와 정신, 성장과 발달, 가족과 건강, 의료와 사회 및 문화, 질병행동, 의사의 본질, 의사-환자 관계, 의사소통 (임상면담), 인간 행태의 심리학적 측면 (사회심리학, 건강과 질병에 대한 인간행태)이 포함되어야 한다. 현재 행동과학 교수요목 가운데 정신과 영역과 의료윤리 영역이 포함되어 있는 것은 정신과학과 의료윤리학 과목에서 강의하는 것이 바람직하다. 본 조사결과와 외국문헌을 참고하여 작성한 바람직한 행동과학 교수요목은 표 9와 같다. 학습시기는 의학과 1학년 및 2학년에 걸쳐 통합교육으로 편성하여 다른 임상실습교육과 연계하여 실시하는 것이 바람직하며, 현재 행동과학의 강의시간 평균 25.2시간을 최소한 48시간 이상으로 늘리고, 소집단 학습, 패널토의, 사례연구, 역할극 및 실습 등의 다양한 학습방법을 개발하여 교육의 효과를 높여야 할 것이다. 교육담당은 정신과학 교수가 단독으로 맡는 것보다 행동과학 관련 교수들이 팀을 이루어 가르치는 것이 권고할 만하다. OBJECTIVES: To survey the behavioral science education in Korean medical schools and to develop a standard syllabus for behavioral science course. SUBJECTS: Professors who are in charge of behavioral science course in 32 medical schools in 1996. METHODS: To develop a standard syllabus of behavioral science course for medical school Delphi technique was used. A questionnaire was mailed to each professor who was in charge of the behavioral science course in 32 medical schools to ask about the course objectives and contents and educational method in January 1996 and 27 questionnaires were completed and returned. The course objectives and syllabi of 27 medical schools were listed and mailed to the same professors to check his/her opinion on the necessity of each item for the behavioral science course. Twenty-three questionnaires were returned and analyzed. The opinion of 23 respondents on each objective and syllabus were listed again and mailed back to the respondents and asked to check if he/she agree with the other respondents opinion. Nineteen questionnaires were collected. From this results a standard syllabus was developed. RESULTS: We recommend that educational objectives of behavioral science course for medical students include understanding of human behavior in biologic, psychologic and sociocultural contexts, understanding of the relationship between body and mind (stress and diseases), acquiring techniques for establishing doctor-patient relationship, and acquiring knowledge and skill for holistic approach to patient care. Recommendable syllabi for behavioral science course are medicine and behavioral science (basic principles of human behavior), body and mind, growth and development, family and health, medical care and society and culture, illness behavior, physician s identity, doctor-patient relationship, communication (clinical interview), and psychologic aspects of human behavior. We recommend that the behavioral science course be offered in the first and second grades of medical students, be integrated into the medical curriculum to link better with clinical courses. Duration of course needs to be expanded from 25.2 hours on the average at present to at least 48 hours. To improve the effectiveness of behavioral science education, it is necessary to develop various teaching methods such as small group discussion, panel discussion, case study, role play and clinical practicum. It is recommended that behavioral science be taught by a team consisted of behavioral scientists and physicians with behavioral science background including psychiatrists instead of by psychiatrist alone.

      • KCI등재

        대전시 공공하수처리시설 유입수 수질자료의 통계적 특성 및 추계학적 모의

        기정 ( Gi Jung Park ),정민재 ( Min Jae Jung ),이한샘 ( Han Saem Lee ),김덕우 ( Deok Woo Kim ),윤재영 ( Jae Yong Yoon ),백경록 ( Kyung Rock Paik ) 한국물환경학회 2012 한국물환경학회지 Vol.28 No.1

        In this study, we analyze statistical characteristics of influent water quality in Daejeon waste water treatment plant and apply a stochastic model for data generation. In the analysis, the influent water quality data from year 2003 to 2008, except for year 2006, are used. Among water quality variables, we find strong correlations between BOD and T-N; T-N and T-P; BOD and T-P; CODMn and T-P; and BOD and CODMn. We also find that different water quality variables follow different theoretical probability distribution functions, which also depends on whether the seasonal cycle is removed. Finally, we generate the influent water quality data using the multi-season 1st Markov model (Thomas-Fiering model). With model parameters calibrated for the period 2003~2005, the generated data for 2007~2008 are well compared with observed data showing good agreement in general. BOD and T-N are underestimated by the stochastic model. This is mainly due to the statistical difference in observed data itself between two periods of 2003~2005 and 2007~2008. Therefore, we expect the stochastic model can be applied with more confidence in the case that the data follows stationary pattern.

      • SCOPUS

        의과대학생의 의학교육 및 의료에 대한 의식 조사

        박정한(Jung Han Park),김경환(Kyung Hwan Kim),전혜리(Hae Ri Jun),이주영(Ju Young Lee) 한국의학교육학회 1999 Korean journal of medical education Vol.11 No.2

        1983년에 전국 규모의 의대생들에 대한 의식 및 가치관 조사를 실시한 이래 그동안 의대 수와 학생정원이 약 2배 증가하였고 사회․경제적 여건도 많이 변하였으므로 의대생들의 의식과 가치관이 어떻게 변하였는지 알아보기 위하여 이 조사를 다시 실시하였다. 1997년 11월 당시 전국의 40개 의대가운데 의학과 4학년까지 재학생이 있는 32개 대학의 의학과 재학생 전원을 모집단으로 하여 각 학년별 학생명부의 출석번호를 이용하여 10명에 1명씩 계통표본추출을 하고, 각 학년의 출석번호 끝번을 추가한 표본을 대상으로 설문조사를 하였다. 설문지는 1983년에 사용한 것을 근간으로 하여 최근 의료환경 변화에 대한 내용과 의대생들의 의학 및 직업관 형성에 관련된 문항을 추가하여 개발하였다. 조사는1997년 12월에서 1998년 1월 사이에 각 대학마다 사전에 위촉된 1명의 조사담당 교수가 조사대상자들에게 설문지를 배부하여 기입하게 하였다. 총 재학생 11,987명중에 설문 조사대상으로 뽑힌 1,386명가운데 1,233명 (89.0%)이 응답하였는데 응답자중 학년 미상 11명과 응답이 부실한 1명을 제외한 1,221명을 최종 분석대상으로 하였다. 몇 가지 특성을 중심으로 모집단과 조사표본을 비교해 본결과 표본의 대표성에는 별 문제가 없었다. 조사내용을 3부분으로 나누어 보고하였는데 1부에서는 조사방법과 조사대상자의 특성 및 응답자들의 의학교육에 대한 태도와 의학에 대한 본인의 적성에 관해 기술하였다. 응답자중 남자가 75.7 %를 차지하였다. 고졸 즉시 의대에 입학한 학생의 비율은 서울지역이 45.8 %, 서울 이외지역은 53.4 %이었다. 본인의 정치적 성향이 보수적이라는 사람이 서울지역은 43.9 %, 서울 이외 지역은 33.0 %로 지방 학생들이 진보적이라는 응답률이 더 높았다. 종교를 가진 사람이 57.2 %이었는데, 기독교가 31.0 %, 가톨릭 15.2 %, 불교 9.5 % 순이었다. 아버지의 교육수준이 대학 또는 그 이상인 사람이 59.8 %로 일반 국민의 교육수준보다 높았다. 아버지의 직업분포도 전문직 21.2%, 회사원 17.2%,공무원 13.1 %, 관리직 11.8 %, 의료인 8.7%로 화이트칼라가 지배적이었다. 의대진학 결정과정에 영향을 미친 사람이 있었다는 사람이 53.7 %이었는데, 이들중 부모가 62.1%를 차지하였다. 의대진학을 권유한 이유중 사회․경제적 측면이 33.5%로 가장 높은 비율을 차지하였다. 의학공부의 재미있는 측면은 생명현상을 배우는것 (47.2 %)과 인간을 배울 수 있다 (44.3%)는 것이었고, 재미없는 측면은 암기식 공부라는 것(39.7%)과 공부 분량이 너무 많다 (34.1%)는 것이었다. 만약 고교 3학년에 되돌아가 다시 대학을 선택할 경우 여전히 의대를 선택하겠다는 사람은 50.3 %이었으나, 지금 전과가 가능하다면 전과하겠다는 사람은 6.0 %에 불과하였다. 의학 공부에 자신의 적성이 맞다는 사람은 64.9%이었고, 이 비율은 학년이 올라갈수록 증가하였다. 장차 자기 아들을 의대에 보내겠다는 사람은 남학생중 36.6%, 여학생중 26.7%였고, 딸을 의대에 보내겠다는 사람은 각각 33.6%, 27.7%이었다. Since the first survey done in 1983, this is the second national sample survey of medical students about their perception and evaluation on medical study, career plan, and medical care system. One out of every 10 students plus one in each class were systematically sampled from each grade year of 32 medical schools in Korea that had students from freshman to senior in November 1997. A questionnaire was developed by adding items related with recent changes in medical care environment and with viewpoint on medicine and physician as an occupation to the questionnaire used in 1983. The questionnaire was administered at each school under the supervision of designated collaborator of the same school in December 1997 through January 1998. A total of 1,386 students were sampled from a total of 11,987 medical students and 1,233 students(89.0%) filled out the questionnaire. Twelve students were excluded from the analysis because of incomplete response and the final analysis was done for 1,221 students. A few demographic characteristics of the sample were compared with those of the study population to check the representativeness of the sample and found no skew. The contents of the study were divided into three parts and the first part describes the study methods, demographic and other characteristics of the sample, students viewpoint on medical education, and students aptitude for medicine Male students accounted for 75.7% of the sample. The proportion of students who entered medical school right after graduating from a high school was 45.8% in Seoul and 53.4% in other than Seoul area. The students who classified their own political inclination conservative were 43.9% in Seoul and 33.0% in other than Seoul and the percentage of students with progressive inclination was higher in out of Seoul than Seoul area. The proportion of students who have a religion was 57.2%; Christian 31.0%, Catholic 15.2%, and Buddhist 9.5%. The educational level of fathers of students was far higher than the level of general population, e.g. 59.8% had college or higher education. Occupation of fathers was mainly white-collar worker; professional worker 21.2%, company employee 17.2%, government official 13.1%, manager 11.8%, and medical professional 8.7%. In the decision-making process to enter the medical school, 53.7% of the students were influenced by someone else and 62.1% of them were parents. Socio-economic factor was the most common reason for recommending medical school and it accounted 33.5% of the reasons. Medical students enjoy learning life phenomenon(47.2%) and human being(44.3%) in medical study but most disturbing factors are memory work(39.7%) and too much to study(34.1%). If students were given another chance to choose a college as a senior student in high school, 50.3% of them said that they would choose medical school. Only 6% of students have intention to change their major subject of study if they are allowed to change now. The proportion of students who consider their scholastic aptitude is compatible with medical study was 64.9% and such proportion increased with grade. The percentage of students who are going to recommend medical school to their own son in the future was 36.6% for male and 26.7% for female students and to their own daughter 33.6% and 27.7%, respectively.

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