성인 코우츠병에서 유리체강내 베바시주맙 주입술 2예

박영숙,손준홍,임한웅,이병로.Young Sook Park. MD. PhD. Jun Hong Sohn. MD. PhD. Han Woong Lim. MD. Byung Ro Lee. MD. PhD 대한안과학회 2009 대한안과학회지 Vol.50 No.4

Purpose: To report the efficacy of intravitreal bevacizumab injection in adult patients with Coats’disease. Case summary: Vascular telangiectasia, microaneurysms, circinate hard exudates, and macular edema were shown in the macula of two patients. Vascular abnormality was limited to≤6 clock hours in both cases. In case 1, the temporal retina demonstrates filigree-like vessels and capillary nonperfusion. In case 2, the nasal retina demonstrates aneurysmal dilatation and multiple microaneurysms. Intravitreal bevacizumab injection was administered in both cases. After 1 month, macular edema decreased. Laser photocoagulation was performed for vascular telangiectasia, microaneurysms, and capillary nonperfusion area. Then an additional decrease of macular edema was observed. Fluorescein leakage decreased, as well. After 1 month (case 1) and 2 months (case 2), macular edema increased. The second and third intravitreal reinjections were administered to each patient. Macular edema decreased. Conclusions: We report two rare cases of Coats’disease in adult patients. Intravitreal bevacizumab injection in patients with Coats’disease can result in a rapid decrease of macular edema, which will then lead to rapid visual recovery and an opportunity for effective laser photocoagulation. We recommend that intraviteal bevacizumab injection be used in combination with laser photocoagulation for the treatment of Coats’disease. J Korean Ophthalmol Soc 2009;50(4):630-634

미래의 직업-미래 일자리 구하기 위한 메가트렌드 보기(2)

박영숙,Park, Yeong-Suk 한국대학교육협의회 2008 大學敎育 Vol.153 No.-

약용식물 추출물의 Helicobacter pylori에 대한 항균 활성과 항산화 활성에 미치는 효과

박영숙,김윤희,Park Young-Sook,Kim Yoon-Hee 동아시아식생활학회 2006 동아시아식생활학회지 Vol.16 No.2

This study was designed to investigate the effect of medicinal herb extract on the antioxidant and antimicrobial activities against Helicobacter pylori, which is known as a ulcerogenic pathogen. The concentration of total phenolic compound of Scutellaria baicalensis(13.14%) was highest among water extracts and that of Ulmus parvifolia(15.12%) was highest among the ethanol extracts. The antioxidant activity of the water extract of Scutellaria baicalensis and of the ethanol extract of Ulmus parvifolia were 91.00% and 65.03%, respectively, in DPPH assay. The antioxidant activity of the water extract of Scutellaria baicalensis and of the ethanol extract of Ulmus parvifolia were 32.90% and 27.70%, respectively, in SOD assay. The antioxidant activity of the water extract of Ulmus parvifolia and of the ethanol extract of Glycyrrhiza uralensis Fischer was 2.15 and 2.17, respectively, in TBARS assay. In disc method, Scutellaria baicalensis showed the highest anti-microbial activity against H. pylori, followed by Glycyrrhiza uralensis Fischer among the water extracts and Glycyrrhiza uralensis Fischer showed the highest anti-microbial activity followed by Radix puerariae among ethanol extract.

약용식물의 증류 추출물을 이용한 기능성 음료 개발에 관한 연구

박영숙,Park, Young-Sook 동아시아식생활학회 2007 동아시아식생활학회지 Vol.17 No.3

The primary objective of this study was to determine the effects of a water-distilled extract with 15 kinds of Korean medicinal herb on antioxidant activity, antimicrobial activity against Helicobacter pylori, and lipid metabolism. The water-distilled extract (WE) and fermenting water-distilled extract (FE) of medicinal herbs were utilized in order to make functional beverages. The EDA (electron donating activity), SOD-like ability, and RAE (relative antioxidant efficacy) of WE averaged 24.47, 50.35, and 1.57%, respectively, but the EDA, SOD-like ability, and RAE of FE was retardeded by 12.01, 35.72, and 1.55%, respectively. The antimicrobial activity against Helicobacter pylori of WE averaged 12.84 mm as a diametric clear zone, and was significantly (p<0.05) higher than those measured in the WE and control. Serum triglyceride contents, total serum cholesterol contents, and serum LDL-cholesterol contents of the WE group were significantly (p<0.05) lower than those of the control group. The liver total-cholesterol contents and liver triglycerides of WE group were significantly (p<0.05) lower than those of the control group. The plasma TBARS value of the WE group was significantly (p<0.05) lower than that of the control group. The sensory evaluation, taste, and smell of FE were more desirable than those of WE, but the color of WE was more desirable. According to the above results, the water distilled extracts (WE) of 15 kinds of medicinal herb are supposed to be effective with regard to antioxidant activity and lipid metabolism, but the antimicrobial activity against Helicobacter pylori was increased as the result of fermentation.

도서관, 독서운동의 메카가 되어야 한다

박영숙,Park, Yeong-Suk 대한출판문화협회 2005 출판저널 Vol.356 No.-

미래의 직업-미래 일자리 변화

박영숙,Park, Yeong-Suk 한국대학교육협의회 2008 大學敎育 Vol.154 No.-

파피러스 코덱스에 관한 고찰

박영숙,Park Young Sook Korean Society For Library And Information Science 1975 한국문헌정보학회지 Vol.4 No.-

일반적으로 파피러스(papyrus)는 4세기에 벨럼(vellum)의 사용으로 그 사용이 대체될 때까지 서양에 있어서 책(冊)의 유일한 재료로서 생각되고 있으며, 또한 파피러스는 두루말이(roll)형태의, 양피지(parchment)는 코덱스(codex) 형태의 도서를 의미하였다고 가정되고 있다. 이 보문(報文)은 문헌조사에 의한 개관으로서, 파피러tm와 코덱스에 대해 각각 서술하였고, 위의 가정을 논했으며, 파피러스 코덱스의 외형에 관하여 기술하였다. 코덱스라는 새로운 형태의 책이 양피지에서부터 시작된 것은 사실이나 두루말이에서부터 코덱스로의 변화가 반드시 도서재료의 변화를 뜻하지는 않는다. 그 최초의 사용시기는 알 수 없으나, 파피러스재료가 코덱스 형태에 차용되었음은 확실하다. 파피러스 코덱스에 대한 참조로서, 84-86년에 쓰여진 마샬(Martial)의 시에서 처음 언급하였으며 카시오도로스 (Cassiodorus)의 저서에 나타난 문귀는 6세기에도 사용되었음을 나타낸다. 확실한 것은 2세기초부터 4세기에 벨럼이 도서의 주재료가 될 때까지 기독교문학 특히 성경에 사용되었음이다. 1897년, 그레코${\cdot}$로망시대의 에집트마을인 옥시링쿠스(Oxyrhnchus)답사에서 그렌휄(Grenfell)과 헌트(Hunt)는 파피러스 책을 처음 발굴하였다. 즉, 200년경에 쓰여진 로기아(Logia;예수교훈집)로서 페이지수가 매겨진 근대도서형태의 단편이었다. 체스터 베이티(Chester Beatty)소장 파피러스는 그 전부가 재료는 파피러스이며, 형태는 코덱스이고, 내용은 기독교문학이다. 이는 파피러스 코덱스가 2세기초부터 기독교도에 치매 사용되어 왔음을 확실하게 말해 준다. 진정한 의미의 도서제본은 파피러스로 만든 코덱스에서 시작되었다. 이는 근대도서와 같이 장(sheet )이나 첩(quire)을 묶어서 제본하였다. 이때의 접는 방법, 배열, 크기 및 종행단(縱行段)에 대해서 기술하였다.

Effect of Ginseng Ethanol Extract on Lactate Dehydrogenate-5 in Rat Brain with Age

박영숙,김태우,조영동,Park, Yeong-Suk,Kim, Tae-U,Jo, Yeong-Dong The Korean Society of Ginseng 1985 Journal of Ginseng Research Vol.9 No.1

Attempts were made to see if feeding of ginseng ethanol extract could affect proper- ties of rat brain lactate dehydrogenase such as specific activity, heat stability, Km for substrate, inactivation by 3-bromopyruvate and trypsin, and immune response. The following results were obtained. Specific activity of LDH was observed to reach maximum in 5 month after birth and then decrease steadily. However, that of LDH from rat fed with ginseng ethanol extract was found in rat fed with ginseng ethanol extract. 3-bromopyruvate was shown to inactivate LDH-5 from old rat fed. Inactivation of LDH-5 by trypsin was remarkable in old rat fed. Km value for pyruvate in old rat fed was remarkably decreased. Cumulative results suggest that ginseng ethanol extract could affect conformational change of LDH responsible for altered properties through unknown mechanism.

노인급식제도 개발을 위한 농촌 노인의 식생활 양상 기초조사 -영양소 섭취 및 건강관련 행동 실태-

박영숙,김순,박기순,이정원,김기남,Park, Young-Sook,Kim, Sun,Park, Ki-Soon,Lee, Joung-Won,Kim, Ki-Nam 대한지역사회영양학회 1999 대한지역사회영양학회지 Vol.4 No.1

A study about health status of the elderly in rural area was performed with 110 home-bound elderly. The results obtained by questionaires and personal interviews recall were as follows. 1) Subjects were 68.6 years of age on average. They revealed the physical tendency of not overweight but high blood pressure. 2) We found that seniors who live alone in rural area were more than in urban area. 3) Average daily intakes of energy and protein of rural elderly were lower than the Korean RDA and the intakes of Ca, riboflavin and niacin in female were also lower. 4) Nutrient intakes were related to family income, food expense, smoking amount, drinking frequency and duration of exercrse, which suggested the needs of nutrition education for the seniors and meal services especially for the low-income elderly.

가스는 문명의 이기이면서 흉기

박영숙,Park, Yeong-Suk 한국화재보험협회 1985 防災와 保險 Vol.25 No.-