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박성경 ( Seong Kyung-park ),진승현 ( Seung Hyeon-jin ),이규민 ( Kyu Min-lee ),권영진 ( Young Jin-kwon ) 한국건축시공학회 2017 한국건축시공학회 학술발표대회 논문집 Vol.17 No.1
Korean apartment buildings have been manhattanized and enlarged, but it caused increase of fire accidents. Fire accidents such as Uijeongbu apartment fire(2015), and Ssangmoon apartment fire(2016) caused many deads because of a lack of emergency exit route awareness. Follow to advanced research, conducted suervey on fire safety awareness. On this study, it will present the basic data based on the result of the survey to secure the life
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만5세 유아의 회복탄력성이 대인관계기술에 미치는 영향 : 문제대처능력의 매개효과를 중심으로
이경돈(Yi, Kyung-Don),김양은(Kim, Yang-Eun),박성경(Park, Seong-Kyung) 한국영유아보육학회 2019 한국영유아보육학 Vol.0 No.118
본 연구는 만 5세 유아의 회복탄력성과 문제대처능력이 대인관계기술에 미치는 영향을 살펴보고, 회복탄력성과 대인관계기술 간의 관계에서 문제대처능력의 매개효과를 검증하는데 있다. 연구대상은 유아교육기관에서 초등학교로 생태학적 전이(ecological transition)를 앞둔 만 5세 유아 213명이었으며 교사의 관찰 및 문답을 통해 설문지로 자료를 수집하였다. 수집된 자료는 상관분석, 회귀분석과 Baron과 Kenny(1986)가 제안한 매개효과 검증에 따라 분석되었다. 연구결과 첫째, 유아의 회복탄력성, 문제대처능력, 대인관계기술은 서로 유의미한 상관이 있었다. 둘째, 유아의 회복탄력성과 문제대처능력은 대인관계기술을 예측하는 변인으로 나타났다. 셋째, 유아의 문제대처능력은 회복탄력성과 대인관계기술 간의 관계에서 부분매개효과를 나타내었다. 본 연구를 통해 회복탄력성이 다소 낮은 유아일지라도 문제대처행동에 대한 인지적 사고과정을 많이 경험하게 한다면 향후 대인관계기술의 어려움으로부터 유아를 보호할 수 있음을 시사하였다. The objective of this study is to examine if the resilience and problem-coping ability of preschooler would predict the interpersonal skills, and also to understand the mediating role of problem-coping ability in the relationship between resilience and interpersonal skills. Targeting 213 young children in five-year old having the ecological transition from early childhood educational institute to elementary school ahead, the data was collected from questionnaires through teachers’ observation and interview with children. The collected data was analyzed by the correlation analysis, regression analysis, and the verification of mediating effects suggested by Baron & Kenny(1986). The results of this study are as follows. First, the resilience, problem-coping ability, and interpersonal skills of young children had significant correlations to each other. Second, the resilience and problem-coping ability of young children were the variables that could predict the interpersonal skills. Third, the problem-coping ability of young children showed the partial-mediating effects on the relationship between resilience and interpersonal skills. This study implies that even young children with low resilience a bit could be protected from difficulties in interpersonal skills in the future if they are exposed to experience lots of cognitive thinking processes about problem-coping behavior.
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PVP분자량에 따른 염산메트포르민 정제의 특성 및 방출거동
김대성 ( Dae Sung Kim ),성경열 ( Kyong Yeol Seong ),김원 ( Won Kim ),홍희경 ( Hee Kyung Hong ),안식일 ( Sik Il Ahn ),박종학 ( Jong Hak Park ),오재민 ( Jae Min Oh ),김윤태 ( Yun Tae Kim ),이은용 ( Eun Yong Lee ),이동원 ( Dong Won 한국조직공학·재생의학회 2009 조직공학과 재생의학 Vol.6 No.4
In this study, metformin HCl, a highly water soluble anti-hyperglycemic agent was prepared into tablet type with PVP of various molecular weights(Mw) to effective oral administration. Because dissolution rate of drug with Mw of PVP becomes decreased as increasing Mw of PVP. We used magnesium stearate as lubricants. We compared the in vitro release behavior of metformin from the tablets according to additives with commercial drug, Diabex(R). The change of structure and crystallinity of tablet by additives were characterized by fourier-transform infrared spectroscopy(FT-IR) and differential scanning calorimeter(DSC). FT-IR and DSC results demonstrate that structure of drug was changed and crystallinity of drug was decreased according to decreasing Mw of PVP. The dissolution rate of metformin HCl from tablet decreased in simulated gastric fluid(pH 1.2) and simulated intestinal fluid(pH 6.8) as increasing K value of PVP. This study suggests Mw of pharmaceutical exipients could effect the metformin HCl release behavior.
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황정규(Jung gyu Hwang),심두보(Doobo Shim),임현정(Hyeon Jeong Im),박상기(Sang Ki Park),강은주(Eun-Ju Kang),조경환(Kyung hwan Cho),배성경(Seong Kyeong Bea),이지현(Ji-hyun Lee),김종철(Jong Cheol Kim) 한국차학회 2018 한국차학회지 Vol.24 No.2
Morphologic and physicochemical changes of shading cultivated tea (Camellia sinensis) tree leaves were investigated during 26 days with 95% shading treatment. Shading cultivation showed higher leaf area (10%) and moisture content (12%) than non-shading cultivation. The shading cultivation increased the total free amino acid (3.4-fold), theanine (3.7-fold), arginine (10.8-fold) and caffeine levels (2.0-fold) but decreased the total catechin contents, EGCG (epigallocatechin gallate) and EGC (epigallocatechin) levels of tea leaves. The SPAD value and total chlorophyll contents of the shading cultivation were increased by 1.1- and 2.1-fold, respectively. The results of a color analysis showed that lightness (L*) of non-shaded was higher than that of shading cultivated matcha. However, the greenness (a*) and yellowness (b*) of shading cultivated matcha were higher than those of non-shading cultivation. The surface color of shading cultivated matcha had higher chroma- and G-values than non-shading cultivated matcha, which represents real green color. Thus, the shading cultivation is suitable to prepare a high-quality matcha product.
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비혈연간 동종조혈모세포이식 환자에서 발생한 다발성 근염 1례
김형준,김동욱,이승훈,김현재,이성수,신호진,박치영,김유진,박윤희,민창기,이석,박성경,이종욱,민우성,김춘추 대한조혈모세포이식학회 2001 대한조혈모세포이식학회지 Vol.6 No.2
조혈모세포이식을 받은 환자에서 만성 이식편대 숙주질환의 증상으로 발생할 수 있는 다발성근염은 전세계적으로 매우 드물게 보고되고 있으며 국내에서는 만성 골수성 백혈병에서 비혈연간 조혈모세포 이식환자에서 만성 이식편대 숙주질환의 증상으로 발생한 다발성 근염의 보고가 아직까지 없는 상태로서 저자들은 본 증례를 통하여 이를 경험하고 치료를 통해 증상의 호전을 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Polymyositis has been described as a rare complication in patients who develop chronic graft versus host disease (GVHD) after allogeneic hematopoietic stem cell transplantation (HSCT). Seven months after HSCT, a 26-year-old man developed polymyositis as a manifestation of chronic GVHD. His symptoms included proximal muscle weakness, myalgia, malaise and weight loss. The clinically suspected diagnosis of polymyositis was confirmed by examining the serum muscle enzymes, electromyographic, and histopathologic findings. Magnetic resonance imaging finding is not routinely used for the diagnosis of polymyositis, but, in our patient, it guided the location of the muscle biopsy and was useful in assessing the disease activity. His clinical condition improved with steroid therapy. We report our experience with 1 case of polymyositis that occurred after unrelated allogeneic stem cell transplantation.
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