부호제약을 이용한 한국 주택시장의 변동요인 분석

민선옥,이영수 한국감정원 2019 부동산분석 Vol.5 No.1

This paper analyzes the dynamic spill-over effects of shocks on housing market, using a six-variable VAR model. As housing market variables, housing price and housing trading volume are used, and as shock variables, housing demand shock, housing supply shock, interest rate shock, household loan shock, aggregate demand shock, and aggregate supply shock are taken into account. The shocks are identified by imposing sign restrictions on the responses of variables. Data analyzed are monthly data from January 2006 to December 2018. The results of analysis are as follows: First, the spill-over effects of the shocks on housing market showed great difference in housing price and housing volume. Second, housing supply shock had relatively great effects on the fluctuation of housing trading volume, housing demand shock had relatively great effects on the fluctuation of housing price, and household loan shock and interest rate shock had greater effects on the fluctuation of housing price than on the fluctuation of housing trading volume. Third, housing supply shock had the greatest influence on housing trading fluctuation, followed by housing demand shock, household loan shock, interest rate shock, aggregate demand shock, and aggregate supply shock. And interest rate shock had the greatest influence on housing price fluctuation, followed by household loan shock, housing demand shock, aggregate demand shock, and aggregate supply shock. Particularly, it is noteworthy that interest rate shock and household loan shock in the financial sector explain more than 50% of housing price fluctuation. 본 연구에서는 주택시장 변수들과 거시경제변수들로 구성된 6개 변수 VAR 모형을 이용하여 여러 가지 충격들이 주택시장에 미치는 동태적 파급 효과를 분석하였다. 주택시장 변수로는 주택(아파트)가격과 주택(아파트)거래량을 사용하였으며, 충격 변수로는 주택공급충격, 주택수요충격, 이자율충격, 가계대출충격, 총수요충격, 총공급충격을 고려하였다. 충격의 식별은 부호제약을 이용하였다. 데이터는 2006년 1월부터 2018년 12월까지의 월간자료이다. 분석결과를 정리하면 다음과 같다. 첫째, 주택시장에 미치는 충격들의 파급 효과는 주택가격과 주택거래량에서 큰 차이를 보인다. 둘째, 주택공급충격은 주택거래량 변동에, 주택수요충격은 주택가격 변동에 상대적으로 커다란 영향을 미치며, 가계대출충격과 이자율충격은 주택거래량보다는 주택가격의 변동에 더 큰 영향을 미친다. 셋째, 주택거래량 변동에 미치는 영향력은 주택공급충격>주택수요충격>가계대출충격>이자율충격>총수요충격 >총공급충격의 순이며, 주택가격 변동에 미치는 영향력은 이자율충격>가계대출충격>주택수요충격>총수요충격>총공급충격>주택공급충격의 순이다. 특히 주택가격 변동에 대한 영향력에서 금융부문 2개 충격의 비중이 50%를 넘어서고 있음은 주목할 만한 결과이다.

The effect of preconditioning on liver regeneration after hepatic resection in cirrhotic rats

민선옥,김성훈,이상우,조진아,김경식 대한간학회 2011 Clinical and Molecular Hepatology(대한간학회지) Vol.17 No.2

Background/Aims:Ischemic preconditioning (IP) decreases severity of liver necrosis and has anti-apoptotic effects in previous studies using liver regeneration in normal rats. This study assessed the effect of IP on liver regeneration after hepatic resection in cirrhotic rats. Methods:To induce liver cirrhosis, thioacetamide (300 mg/kg) was injected intraperitoneally into Sprague-Dawley rats twice per week for 16 weeks. Animals were divided into four groups: non-clamping (NC), total clamping (TC), IP, and intermittent clamping (IC). Ischemic injury was induced by clamping the left portal pedicle including the portal vein and hepatic artery. Liver enzymes alanine transaminase (ALT) and aspartate aminotransferase (AST) were measured to assess liver damage. Terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling (TUNEL) staining for apoptosis and proliferating cell nuclear antigen (PCNA) staining for cell replication were also performed. Results:Day-1 ALT and AST were highest in IP, however, levels in NC and IC were comparably low on days 1-7. There was no significant correlation of AST or ALT with experimental groups (P=0.615 and P=0.186). On TUNEL, numbers of apoptotic cells at 100× magnification (cells/field) were 31.8±24.2 in NC, 69.0±72.3 in TC, 80.2±63.1 in IP, and 21.2±20.8 in IC (P<0.05). When regeneration capacity was assessed by PCNA staining, PCNA-positive cells (cells/field) at 400× were 3.4±6.0 in NC, 16.9±69 in TC, 17.0±7.8 in IP and 7.4±7.6 in IC (P<0.05). Conclusions:Although regeneration capacity in IP is higher than IC, the liver is vulnerable to ischemic damage in cirrhotic rats. Careful consideration is needed in applying IP in the clinical setting.

토론연극을 활용한 부모역량 강화 프로그램 개발 및 적용

민선옥,배지희 한국유아교육학회 2018 정기학술대회 논문집 Vol.2018 No.-

본 연구는 토론연극을 활용한 부모역량 강화 프로그램을 개발하고 그 영향을 밝히고자 하는데 목적이 있다. 이를 위해 부모교육과 토론연극에 관한 문헌연구, 요구조사와 전문가 협의, 예비연구를 토대로 프로그램을 개발하였다. 본 프로그램은 교육목적 및 목표, 교육내용, 교수-학습방법, 평가로 구성되었다. 개발된 프로그램은 유치원에 재원하는 자녀를 둔 어머니 8명을 대상으로 2017년 3월 29일부터 6월 7일까지 총 10회기에 걸쳐 적용되었고, 참여관찰, 면담, 연구일지 작성, 그리고 저널쓰기를 통하여 자료를 수집하였다. 연구결과, 토론연극을 활용한 부모역량 강화 프로그램에 참여한 어머니들에게서 개인으로서의 변화, 부모역할의 변화, 그리고 양육태도의 변화가 나타났다. 이는 부모 자신에 대한 이해를 바탕으로 부모역량을 강화시키는 부모교육 프로그램이 효과적임을 시사하는 것이다.

영유아기 자녀를 둔 어머니들의 사교육에 대한 인식과 경험

민선옥,배지희 한국육아지원학회 2014 한국육아지원학회 학술대회지 Vol.2014 No.4

구연 : 그랜드볼룸 ; 지방유래 중간엽 줄기 세포의 증식 및 유착에 미치는 ECM의 역할 (초)

민선옥,이상우,최새별,김경식 대한간학회 2010 Clinical and Molecular Hepatology(대한간학회지) Vol.16 No.3(S)

딥러닝 기반 나이 예측과 자연어처리를 활용한 의류추천 시스템

민선옥(Sunok Min),최영인(Youngin Choi),김동균(Dongkyun Kim),이주현(Joohyun Lee) 한국통신학회 2020 한국통신학회 학술대회논문집 Vol.2020 No.8

성장인자를 제외 한 배양액에서의 간암세포주의 구체 형성 배양

민선옥(Seon Ok Min),이상우(Sang Woo Lee),박선영(Seon Young Bak),김경식(Kyung Sik Kim) 대한종양외과학회 2015 Korean Journal of Clinical Oncology Vol.11 No.1

Purpose: Cancer stem cells have the characteristics similar to the normal stem cell but are cancer cells. Sphere forming culture has been adapted as a culture method for cancer stem cells. In this study, we validated to optimal culture condition for sphere formation of hepatocellular carcinoma cell line using three different types of culture media. Methods: Huh7 cells were plated in different culture media allowed for sphere formation. M1, Dulbecco’s Modified Eagle’s medium (DMEM)-high glucose with fetal bovine serum (FBS); M2, DMEM-high glucose without FBS; and M3, DMEM-F12 (Gibco, Grand Island, NY, USA) with B27, epidermal growth factor, basic fibroblast growth factor (bFGF, Invitrogen, Seoul, Korea). Sphere formation was observed by light microscope. Proliferation of the sphere-forming cells was evaluated by Cell counting kit-8 (CCK-8) analysis. Results: Cells in M1 and M3 media were formed sphere. Sphere-forming cells in M1 and M3 were bigger than M2 cells and had similar morphology. Sphere-forming cells in M3 media showed higher level of cell proliferation than M1 and M2 cells on 15 days, while sphere-forming cell in M1 media were exhibited higher level than others on post 20 days. Proliferation of M2 cells did not improve. Conclusion: Results showed that sphere-forming cells in M1 and M3 media had similar character. So, it is assumed that a growth factor- free medium is adaptable or efficient tool for in vitro cultivation of cancer stem cells, because the tool shall be reduced expense for experiments without the adding of growth factors.

초기 청소년기 자녀가 지각한 부모의 양육태도가 정신건강에 미치는 영향 :

민선옥(Sun Ok Min),강영숙(Young Sook Kang) 연세대학교 사회복지연구소 2015 한국사회복지조사연구 Vol.44 No.-

본 연구는 부모의 양육태도가 초기 청소년의 정신건강에 미치는 영향을 파악하고, 두 변수간에 관계에서 또래관계가 매개효과를 갖는지 검증하는데 목적이 있다. 조사대상은 전라북도에 거주하고 있는 초기 청소년기에 해당하는 중학생 2학년이다. 2012년 7월 5일~16일에 걸쳐 실시하였고, 총 628명이 설문에 응답하였다. 최종분석에는 불성실하게 응답이 된 44부를 제외한 584부가 사용되었다. 자료 분석은 SPSS 18.0 프로그램을 사용하여 기술 통계, 상관관계분석, 회귀분석 그리고 Sobel test를 통하여 매개효과를 검증하였다. 분석결과 부모의 양육태도는 초기 청소년기 자녀의 정신건강에 유의미하게 영향을 미치는 것으로 나타났다. 다음으로 또래관계를 매개로 초기 청소년 자녀의 정신건강에 미치는 영향을 분석한 결과 유의미하게 영향을 미치는 것으로 나타났다. 즉 부모양육태도가 초기 청소년의 정신건강에 긍정적인 영향을 주는 직접적인 효과가 유의함과 동시에 또래관계는 부모양육태도와 초기 청소년의 정신건강 사이에서 부분 매개효과를 보이고 있었다. The objective of this study is to find out the effects of parents’ attitudes toward rearing on the mental health of adolescents and to verify if a peer relationship will function as a medium in the relation between parents’attitudes toward rearing and the mental health of the adolescents. The Data were collected about the second grade students from 6 middle schools in Jeonju city, Iksan city and Kunsan city and 4 middle schools in Jinan gun, Buan gun, and Imsil gun, Jeollabukdo. Out of 628 respondents in questionnaires, 585 copies were analyzed. The way to collect data was done by self-administered questionnaire survey, which were conducted from July 5 to July 16, 2012. The main results of this study are as follows; first, the results of the analysis about the effects on the mental health of the adolescents showed that parents’attitudes toward rearing have significant effects on the mental health of adolescents. Second, the results of the analysis about the effects of parents’attitudes toward rearing on the health of adolescents through a medium of peer relationship showed that gender, school record, the number of friends, family form, income, health, and Internet have significant effects on it. The study analyzed the effects of parents’attitudes toward rearing on the mental health of the adolescents and medium effect of peer relationship. It is expected to be provided as basic data to develop educational programs to improve the mental health of the adolescent children and change parents’attitudes toward rearing, and to develop group programs to help the adolescents make positive peer relationship and improve their health.

Human Adipose Tissue-Derived Mesenchymal Stem Cells 배양 시 효율적인 Extracellular Matrix의 증명

민선옥(Seon Ok Min),이상우(Sang Woo Lee),최새별(Sae Byeol Choi),김경식(Kyung Sik Kim) 한국간담췌외과학회 2009 한국간담췌외과학회지 Vol.13 No.4

Purpose: Human mesenchymal stem cells (hMSCs) have the potency for self-renewal and differentiation into various kinds of cells. The hMSCs are obtained from the various tissues, including adipose tissue, bone marrow and cord blood. The extracellular matrix (ECM) is an important factor that affects cell adherence, growth, migration, apoptosis and differentiation both in vitro and vivo. The adipose-derived mesenchymal stem cells (AD-MSCs) have CD29 (integrin) on the cell surface, which is the receptor for fibronectin. The aim of this study is to validate the efficacy of ECM, and especially fibronectin, for cell expansion. Methods: The AD-MSCs were obtained from the abdominal fat of humans. These cells were seeded onto culture plates coated with fibronectin-Human (FN) and plates without ECM (control). The cells were incubated for 3 passages and the cellular morphology was simultaneously observed with microscopy. CCK-8 assay was performed to compare the proliferation ability in each condition at the same passage. Immunocytochemistry staining for integrin-beta1 was performed to observe the cell to cell interaction. Results: The hAD-MSCs in the FN-coated and non-coated plates exhibited cytoplasm staining for integrin-beta1. In all the cultures, extended fibroblastic-shaped cells that turned into rhomboid cells were most frequently observed. The cell growth rates for the non coated culture plate were lower than those for the FN coated plates. After 72 hour culture under the different coated concentrations of FN and the non coated condition (control), the control group had a lower growth rate. In the culture with a FN coated plate, a significant change was observed as compared with that of the control group. We observed an increase in cell proliferation, with a maximum of 140%, on the FN coated plate by performing CCK-8 assay. In comparison, integrin β1 on the cells was more expressed in the FN-coated plates than that in the non-coated plates. Conclusion: The cell morphology can be changed faster in the FN coated culture plates than that in the non coated culture plates. Because proliferation and adhesion with FN can enhance the expansion, the culture within a FN coated plate is needed to encourage hAD-MSCs to proliferate in vitro.

스마트 어린이집 모델개발과 그 이후

민선옥(Min, Sun-Ok) 대한건축학회 2023 建築 Vol.67 No.7