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진행성 유방암에 있어 유방절제술 후 발생한 광범위 피부결손 부위의 가슴배피판을 이용한 흉벽재건술
김학태,양정덕,정호윤,조병채,김귀락,최강영,이정훈,박호용,Kim, Hak-Tae,Yang, Jung-Dug,Chung, Ho-Yun,Cho, Byung-Chae,Kim, Gui-Rak,Choi, Kang-Young,Lee, Jung-Hun,Park, Ho-Yong 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.6
Purpose: Radical surgical extirpation in advanced breast cancer patients produces extensive loss of skin with large defects requiring plastic surgical procedures for the closure. Many reconstructive methods exist, the choice of which depends upon the characteristic of the wound, extent of resection and patient comorbidities. For adequate coverage of the large skin defects following resection of advanced breast cancer, current authors have performed a thoracoabdominal flap. Methods: From August 2008 to June 2009, 4 cases of thoraco-abdominal flap were performed for chest wall reconstruction after mastectomy of advanced breast cancer. Flap dissection was entirely performed in a subfascial plane and the flap involving the external oblique abdominal muscle. The flap was rotated clockwise in left chest wall defects and counterclockwise in right chest defects and the donor site was closed directly. Results: Their mean age, 55.7 years and the average follow-up interval was 9 months. Patients' oncologic status ranged from stage IIIc to stage IV, it was classified according to the TNM staging system. Flap dimensions ranged between $15{\times}15$ and $25{\times}25\;cm$. One flap sustained a partial loss at the distal margin and revision with pectoralis major musculocutaneous island flap. Conclusion: Large chest wall reconstructions are usually required after radical excision of advanced cancer stages patients with poor general conditions. Thoracoabdominal flap is a simple, quick single-stage procedure, and offer to patient fast recovery, low complication rate, enabling further concomitant adjuvant therapy.
BMP-2를 함유한 2상 알지네이트 담체를 이용한 골수줄기세포의 골분화
임현주,김학태,오은정,김태정,김한도,최진현,정호윤,Lim, Hyun-Ju,Kim, Hak-Tae,Oh, Eun-Jung,Kim, Tae-Jung,Ghim, Han-Do,Choi, Jin-Hyun,Chung, Ho-Yun 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.3
Purpose: The object of this study is to develop a novel BMP-2 delivery system for continuous osteogenic differentiation and to induce osteogenesis of stem cells using a bi-phase alginate carrier in vitro. Methods: Alginate nanoparticle loaded BMP-2 was prepared by the reverse emulsification-diffusion technique. Physical properties and release profiles of alginate carriers were measured by Instron and ELISA kit, respectively. Cell viability and alkaline phosphate activity of hBMSCs differentiation was also evaluated by MTS and Metra BAP assays, respectively. Results: Optimal concentration for bi-phase alginate carrier was determined as 2 wt% by evaluating mechanical and biological properties, and differentiation of BMSCs for bone regeneration. The 2% bi-phase alginate carrier had the lowest initial and final release ratio. In addition, the 2% bi-phase alginate carrier had a little higher ALP activity than the homogeneous carrier. An improved controlled release profile was obtained by combining alginate hydrogel with lyophilized particles. Conclusion: Bi-phase alginate carrier has many advantages such as biocompatibility and controlled release capability. It is expected to be effective as a scaffold and carrier in bone tissue engineering.
3차원 형상의 SMA작동기를 사용한 타원형 실린더의 변형제어
김철(Cheol Kim),이성환(Sung-Hwan Lee),김학태(Hak-Tae Kim) 대한기계학회 2002 대한기계학회 춘추학술대회 Vol.2002 No.5
Shape memory alloys (SMAs) are often used in smart materials and structures as the active components. Their ability to provide a high force and a large displacement has been used in many applications. In this paper the radial displacement control of an externally pressurized elliptic composite cylinder where the SMA strip actuators are bonded on its outer surface is investigated numerically. The composite elliptic cylindrical shell consisting of an inlet duct system with SMA strips was designed and analyzed to determine the feasibility of such a system for the removal of stiffeners from the externally pressurized duct of an aircraft inlet. The SMA strips start to transform from the martensitic into the austenitic state upon actuation through resistive heating, simultaneously recover the prestrain, and thus cause the composite cylinder to expand in the radial direction. The externally pressurized elliptic composite cylinder with the SMA strip actuators is analyzed using the commercially available nonlinear finite element code ABAQUS. The incremental SMA constitutive model based on a return mapping algorithm is implelemented in user supplied subroutine UMA T. The results show that the role of stiffeners can be replaced by the activated SMA strip actuators.
정신지체아 100m 달리기 지도 및 평가방법에 관한 연구
전중기,김학태 大邱大學校 障碍人綜合硏究所 1997 特殊敎育硏究 Vol.20 No.-
본 연구는 정신지체아 체육의 내실 있는 수업과 신뢰성 있는 평가, 그리고 정신지체아들의 단거리 달리기 능력을 신장시키기 위해 단거리 달리기 지도방안을 제시하고 이에 따른 타당성 있는 평가방법을 모색하기 위해 제주도 소재 "J"특수학교 학생 중 교육가능급 정신지체아(IQ 51~75) 50명(중등부 25명, 고등부 25명)을 대상으로 새로운 수업방법과 평가방법에 의한 주 2시간씩, 총 16시간의 수업을 한 결과 새로운 수업방법과 평가방법에 의해서 100m 달리기기록, 출발법, 중간질주법, 피니쉬법 평가점수가 현저히 높게 나타났다. 그리고 5단계 평가점수와 100m 기록과 실험후의 상관계수 R=0.83으로서 유의한 것으로 나타났다. (p<0.5) 따라서 본 연구의 새로운 수업방법과 평가방법이 정신지체아의 단거리 달리기 능력을 향상시킬 수 있을 것으로 사료된다. The purpose of this study is to explore the method of estimation and increased 100 m race ability. This new method of teaching and estimating attempted the experiment with 50 students (with IQ's of 51~75, 25 middle school students and 25 high school students). These mentally retarded students with educational possibilities attend "J" special school student in Che-ju Do. The itemized conclusions findings of this study are as follows: 1. With the new teaching method, the 100 m race record is 1.77 seconds faster than the old record. · Old record: 19.05(±1.93) · New record: 17.28(±1.33) 2. Estimating point of starting system appeared 0.5 points high by 5 grades using the new method. · Before experiment record: 3.22(±1.14) · After experiment record: 3.72(±1.04) (p<0.05) 3. The estimating points method of the middle scamper event appeared 0.4 points higher by 5 grades estimation. · Before experiment record: 3.38(±1.00) · After experiment record: 3.78(±1.02) 4. The estimating points method of the finish appeared 1 point higher by 5 grades estimation. · Before experiment record: 2.94(±1.03) · After experiment record: 3.94(±1.00) (p<0.01) 5. It appeared that the coefficient of correlation if R=0.83 between the 100m race record and 5 grades estimation record after the experiment.