벌독으로 인한 혈청병 양상의 두드러기 및 맥관부종 치험 1례

김정현,강다혜,김지영,임해원,김자헌,권강,Kim, Jung-Hyun,Kang, Da-Hae,Kim, Jee-Young,Lim, Hae-Won,Kim, Ja-Heon,Kwon, Kang 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.3

Objective : This study was performed to prove the effect of the oriental medical treatments on urticaria and angioedema caused from serum sickness reaction by bee venom. Method : We treated one case of urticaria and angioedema with oriental medical treatments such as 8 constitution acupuncture, herbal medicine, venesection therapy and facial pack therapy. We took pictures through the treatment to evaluate the improvement. Six items, itching, burning sensation, pain, wheal, redness, edema were used to diagnose urticaria and angioedema. Result & Conclusion : After treatments the urticaria and angioedema were improved. The symptom of itching, heating, pain, wheal, redness of whole body and facial edema disappeared.

사용자지정 재료 서브루틴을 활용한 LNG선박 단열시스템 멤브레인의 수치해석

김정현,김슬기,김명수,이제명,Kim, Jeong-Hyeon,Kim, Seul-Kee,Kim, Myung-Soo,Lee, Jae-Myung 한국전산구조공학회 2014 한국전산구조공학회논문집 Vol.27 No.4

304L 스테인리스강판은 멤브레인타입 LNG선 단열시스템의 1차 방벽으로 이용된다. 304L 스테인리스강은 변태유기소성(TRIP)강으로 복잡한 재료거동을 보이는데, 이는 소성변형이 발생하는 동안 상변태를 경험하기 때문이다. 본 연구에서는 304L 스테인리스 강의 비선형 기계적 거동분석을 위한 온도의존 일축인장시험을 수행하였으며 재료의 파단이나 비선형 거동을 예측하기 위한 점소성모델을 제안하였다. 수치해석의 결과와 시험 결과를 비교 분석하여 유효성을 검증하였으며 LNG 멤브레인에 대한 적용성을 검토하기 멤브레인 구조시편을 제작하여 구조해석 및 유한요소해석을 수행하였다. 재료모델은 개발 서브루틴을 이용하였으며 ABAQUS 사용자지정 재료 서브루틴을 탑재한 유한요소해석 결과와 극저온 구조인장시험을 수행한 결과를 비교하여 구조적용성을 검증하였다. 304L stainless steel sheets are used as a primary barrier for the insulation of membrane-type liquefied natural gas(LNG) carrier cargo containment system. 304L stainless steel is a transformation-induced-plasticity(TRIP) steel that exhibits complex material behavior, because it undergoes phase transformation during plastic deformation. Since the TRIP behavior is very important mechanical characteristics in a low-temperature environment, significant amounts of data are available in the literature. In the present study, a uniaxial tensile test for 304L stainless steel was performed to investigate nonlinear mechanical characteristics. In addition, a viscoplastic model and damage model is proposed to predict material fractures under arbitrary loads. The verification was conducted not only by a material-based comparative study involving experimental investigations, but also by a structural application to the LNG membrane of a Mark-III-type cargo containment system.

과루인약침(瓜蔞仁藥鍼)이 Ovalbumin-induced Asthma Mouse Model에 미치는 영향(影響)

김정현,백경민,이현의,김종원,오병열,조현경,유호룡,김윤식,설인찬,심재철,Kim, Jung-Hyun,Baek, Kyung-Min,Lee, Hyun-Eui,Kim, Jong-Won,Oh, Byeong-Yeol,Jo, Hyun-Kyung,Yoo, Ho-Rhyong,Kim, Yoon-Sik,Seol, In-Chan,Shim, Jae-Chul 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3

Objectives : The aim of this study was to investigate the effect of Trichosanthis Semen Herbal-acupuncture(TS-HA) at Joksamni(ST36) on ovalbumin-induced asthma in mice. Methods : C57BL/6 mice were sensitized and challenged with ovalbumin(OVA) once a week for twelve weeks. The experimental group was treated with 1% concentrations of TS-HA at Joksamni(ST36) three times a week for the last eight weeks. Results : 1. The weight and total lung cells of the mice in the group treated with TS-HA decreased significantly compared with those of control group. 2. Total leukocytes and eosinophils in Bronchoalveoler-lavage fluid(BALF) of the mice in the group treated with TS-HA decreased significantly compared with those of control group. 3. Eosinophils in BALF of the mice in the group treated with TS-HA in photomicrographs decreased significantly compared with those of control group. 4. According to histological analysis of lung sections, adhension of collagen in TS-HA decreased significantly compared with that of control group. 5. The concentration of IgE, IL-4, IL-5 in BALF and IL-4, IL-5, IL-13 in serum of the mice in the group treated with TS-HA decreased significantly compared with that of control group. 6. The number of $Gr-^+/CD11b^+,\;CD11b^+,\;CD3e^-/CCR3^+,\;CD4^+,\;CD8^+\;CD3e^+/CD69^+,\;CD23^+/B220^+\;cells$ in the lungs of the mice in the group treated with TS-HA decreased significantly compared with those of control group. Conclusion : These results suggest that Trichosanthis Semen-herbal acupuncture at Joksamni(ST36) done on C57BL/6 mice is effective in part in relieving OVA-induced asthma in C57BL/6 mice.

랜덤화 블록 계획법에서 우산형 대립가설에 대한 정렬방법과 위치를 이용한 비모수 검정법

김정현,김동재,Kim, Jeonghyun,Kim, Dongjae 한국통계학회 2016 응용통계연구 Vol.29 No.7

랜덤화 블록 계획법(randomized block design)에서 대립가설형태에 따라 많은 비모수적인 방법들이 제안되었다. 일반대립가설에서 대표적으로 Fridman (1937)의 검정법이 있고, 순서형 대립가설에서는 Page (1963)의 검정법이 있다. 우산형 대립가설에 대한 비모수적 방법으로는 일원 배치 모형에서 k개의 표본 문제에 대하여 Mack과 Wolfe (1981)의 검정법이 있다. 본 논문에서는 랜덤화 블록 계획법(randomized block design)에서 우산형대립가설에 대하여 블록 간의 정보를 이용한 Hodges와 Lehmann (1962)의 정렬방법과 위치를 이용한 Kim (1999)의 검정법을 이용하여 검정법을 제안하였다. 또한, Monte carlo 모의실험을 통하여 제안된 검정법과 기존의 검정법을 비교하였다. Nonparametric methods in randomized block design were suggested by Friedman (1937) for general alternatives and were also proposed by Page (1963) for ordered alternatives in one-way layout; in addition, K-sample rank tests for umbrella alternatives were suggested by Mack and Wolfe (1981). In this paper, we proposed a nonparametric method of umbrella alternatives for randomized block design using the aligned method proposed by Hodges and Lehmann (1962) to use block information and using placement suggested by Kim (1999). Monte Carlo simulation was also adapted to compare the power of the proposed procedure with previous methods.

다운로딩(Downloading)에 의한 정보봉사

김정현,Kim, Jeong-Hyeon 한국도서관협회 1990 圖協會報 Vol.31 No.3

한국십진분류법 제6판 사회복지학 분야의 분류체계 수정 전개 방안

김정현,Kim, Jeong-Hyen 한국도서관정보학회 2017 한국도서관정보학회지 Vol.48 No.3

이 연구는 사회복지학의 학문적 특성과 분류체계를 비교 분석함으로써, 사회복지학의 분류특성과 문제점을 분석하고 이를 토대로 KDC 제6판 사회복지학의 분류체계 수정 전개 방안을 제시하였으며, 연구결과를 요약하면 아래와 같다. 첫째, 사회복지학의 주요 영역에는 사회복지정책 및 행정을 비롯한 사회복지 일반, 각종 사회사업, 장애인, 아동청소년, 노인, 여성, 가족 등 각 계층이나 집단별 복지서비스가 포함된다. 둘째, 국립중앙도서관의 유별 자료 분석결과, 상대적으로 복지정책 및 행정, 연금, 보호 서비스, 다문화가족을 비롯한 소외계층 지원 등의 주제어에 빈도수가 높게 나타났으며, 이들 항목에 대한 세목을 신설하였다. 셋째, 분류항목의 수정 전개는 원칙적으로 사회복지학의 학문적 특성과 주제어 분석을 바탕으로 하였으며, 혼란을 줄일 수 있도록 가능한 한 기존의 KDC 분류체계를 유지하였다. This study investigated general problems concerning the social welfare field in the KDC 6th edition based comparative analysis academic characteristics and classification system, and suggested on some ideas for the improvements of them. Results of the study are summarized as follows. First, a main field of the social welfare is generally divided into a general social welfare, social works, and social welfare services to special classes and groups including people with disabilities, young people, aged, women, and families. Second, I analyzed on social welfare from the collection database at the National Library of Korea. Based on analysis of the data. the keyword frequency of social welfare policy and management, pensions, care services, and support works for the underprivileged was relatively high. Third, modified classification of items was basically performed through the academic characteristics of the social welfare and the keyword analysis, and maintaining the existing KDC classification system caused less confusion as much as possible.

음주에 따른 음성 변화에 대한 고찰

김정현,윤제환,조형호,조연,조재식,Kim, Jung-Hyun,Yoon, Je-Hwan,Cho, Hyung-Ho,Cho, Yeon,Cho, Jae-Sik 대한후두음성언어의학회 2002 대한후두음성언어의학회지 Vol.13 No.1

Background and Objectives : It has been pointed out that alcohol intake in human beings induces changes in voice register and maximum phonation time. These changes supposedly result from injection of the vibratory vocal folds. The purpose of this study was to clarify the voice changes associated with alcohol intake and the changes of laryngeal mucosa. Materials and Methods : The subjects included 29 volunteers, including 20 men and 9 women ranging in age from 22 to 31 years. Alcohol intake was accomplished by oral administration of 23% soju 1 bottle (255cc). Serum alcohol concentration levels were evaluated hourly for 3 h after ingestion of alcohol. Seven measurements were performed at pre-alcohol intake and post-alcohol intake hourly : fundamental frequency, jitter, shimmer, noise to harmonic ratio as the acoustic analysis, maximal phonation time, mean flow rate, and subglottal pressure as the aerodynamic analysis. The changes of laryngeal mucosa were evaluated by flexible laryngoscope at each measurement. Results : By comparing the acoustic and aerodynamic data and laryngeal mucosa before and after alcohol intake, there were not remarkable changes (p>0.05). Conclusion : The voice and laryngeal mucosa have not remarkably changed according to alcohol concentration in this study. Furthermore studies on the voice change induced by multiple alcohol concentrations are required.

Anti-lipase and Lipolytic Activities of Ursolic Acid Isolated from the Roots of Actinidia arguta

김정현,김진숙,장대식,Hyojun Kim 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.7

The aim of this study was to investigate the anti-obestic effects of ursolic acid isolated from the roots of Actinidia arguta, as well as the mechanism of action of this compound. This was conducted by testing whether ursolic acid inhibited the elevation of the rat plasma triacylglycerol levels after oral administration of a lipid emulsion containing corn oil in rats. Ursolic acid prevented the elevation of plasma triacylglycerol levels 2 h after oral administration of the lipid emulsion at a dose of 100 mg/kg. Furthermore, ursolic acid inhibited phosphodiesterase activity in vitro with an IC50 of 51.21 μM and enhanced lipolysis in rat fat cells. We suggest that the inhibitory effects of ursolic acid, isolated from the roots of A. arguta, on obesity, might be attributable to the inhibition of lipid absorption through the inhibition of pancreatic lipase and by enhancing lipolysis in fat cells.

중국 기생충관리 현지 조사를 마치고 / 난닝팀

김정현,Kim, Jeong-Hyeon 한국건강관리협회 1997 건강소식 Vol.21 No.12

도서관에 있어서 뉴미디어의 이용

김정현,Kim, Jeong-Hyeon 한국도서관협회 1988 圖協會報 Vol.29 No.4