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조성관,김선정,정병옥,김재진,최규석,이영무 ( S . K . Cho,S . J . Kim,B . O . Jung,J . J . Kim,K . S . Choi,Y . M . Lee ) 한국공업화학회 1994 공업화학 Vol.5 No.5
게껍질로부터 Hackman법으로 키틴을 추출하였고 키토산은 이것을 일정 온도(100℃)에서 NaOH 용액의 농도와 반응 시간을 변화시켜 각각의 탈아세틸화 정도에 따라 제조하였다. 제조한 시료들은 A=19%, B=52%, C=70% 그리고 D=93%의 탈아세틸화된 것을 사용해 여러 가지 시험을 하였다. 분자량은 탈아세틸화도가 증가함에 따라 감소되는 현상을 나타냈고, 폐수처리 효과에 있어서 SS 제거율은 탈아세틸화도가 증가함에 따라 증가하였고 pH 9에서 우수한 성능을 나타냈으며, COD 제거율은 중성 영역에서 가장 좋게 나타났다. Chitin was extracted from crab shell by Hackman method and chitosan was prepared to chitin, that was deacetylated under various concentration of NaOH solution and reaction time at constant temperature, 100℃. Samples were A=19%, B=52%, C=70% and D=93% deacetylation`s chitosan and they were tested. When deacetylation was increased, Mw ̄ was decreased and removal rate of suspended solid and removal rate of chemical oxygen demand were increased. Suspended solid and removal rate of chemical oxygen demand showed the better at pH 9 and pH 7 than any other pH range.
Blood Pulsation의 효과가 뇌 활성화에 미치는 영향을 알아보는 방법
이원호,구정훈,이형래,한기완,박진식,김재진,윤강준,김인영,김선일,Lee, W.H.,Ku, J.H.,Lee, H.R.,Han, K.W.,Park, J.S.,Kim, J.J.,Yoon, K.J.,Kim, I.Y.,Kim, S.I. 대한의용생체공학회 2007 의공학회지 Vol.28 No.3
BOLD T2*-weighted MR images reflects cortical blood flow and oxygenation alterations. fMRI study relies on the detection of localized changes in BOLD signal intensity. Since fMRI measures the very small modulations in BOLD signal intensity that occur during changes in brain activity, it is also very sensitive to small signal intensity variations caused by physiologic noise during the scan. Due to the complexity of movement of various organs associated with heart beat, it is important to reduce cardiac related noise rather than other physiological noise which could be required with relatively simple method. Therefore, a number of methods have been developed for the estimation and reduction of cardiac noise in fMRI study. But, each method has limitation. In this study, we proposed a new estimation method for brain activities influenced by blood pulsation effect using regression analysis with blood pulsation signal and the correspond slice of fMRI. We could find out that the right anterior cingulate cortex and right olfactory cortex and left olfactory cortex were largely influenced by blood pulsation effect for new method. These observed areas are mostly on the structure of anterior cerebral artery in the brain. That is convinced with that our method would be valid and our new method is easier to apply in practice and reduce computational burden than the retrospective method.