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최만용(Man-Yong Choi),채경희(Kyung-Hee Chae),김기복(Ki-Bok Kim),김수언(Su-Un Kim) 대한설비공학회 2009 대한설비공학회 학술발표대회논문집 Vol.2009 No.-
Until now for the safety of structures and equipment monitoring technology to measure the amount of the physical, if that is the one, one-point or single-source target is one the most. Therefore, becoming more numerous and complex to measure the amount of physical measurement technology that is comprehensive and complex, multi-source concepts to the monitoring of a multi-sensing technology is required. Have the same characteristics of multi-source multi-use space such as a multi-structure of facilities/equipment is. The people's safety in a multi-use facility will be directly related to life and even a little carelessness can lead to large-scale disaster occurs because of several factors, risks and to manage detect in advance the development of an intelligent monitoring technology is essential. Therefore, this study shows that multiple structures/facilities to improve the quality of human life in research to maintain a safe and comfortable living space for multi-source intelligence to the development of monitoring technology to achieve that goal, and the ubiquitous sensor network system on the basis of the wireless transmission module, and multiple research facilities/equipment for the ultra-small sensors for health monitoring study was performed.
산양(山羊)의 Liver cirrhosis 발생보고(發生報告)
민병만 ( Byeong Man Min ),박경애 ( Kyeong Ae Park ),김환균 ( Hwan Gyun Kim ),조용성 ( Young Sung Cho ),김성렬 ( Seong Rhyul Kim ),구찬회 ( Chan Hoei Koo ),정운익 ( Un Ik Chung ),김홍보 ( Hong Jip Kim ) 한국가축위생학회 1993 韓國家畜衛生學會誌 Vol.16 No.1
This survey was performed to report rare outbreak of liver cirrhosis in Korean native goat (KNG) which was died of Yangpyeong`s goat farm on Feb. 1992. The examination for the KNG was carried out by clinical signs, necropsy and various laboratory test including parasitic, bacterial and histological test. The KNG looked jaundice, ascite, hemorrhage of rumen, abomasum and intestine, and brownish smooth cirrhotic liver at necropsy. Histological examination for liver revealed considerable proliferation of connective tissue and piecemeal necrosis which was caused by chronic active inflammation in interlobules and intralobules. There were atrophic micro and macro nodules which were surrounded by connective tissue. The lobular structure lack almost all central vein. The portal areas appearred proliferation of bile ducts, blood vessels and connective tissues. These connective tissue infiltrated heavily with plasma cells, lymphocytes and histocytes. Histological examination for brain proved to be hepatic encephalopathy by virture of congestion and edema in cerebral medullary. From these results were demonstrated mixed nodular, active, postnecrotic liver cirrhosis.
FDG 사용 시 Dose Calibrator에 따른 SUV에 미치는 영향
박영재,방성애,이승민,김상언,고길만,이경재,이인원,Park, Young-Jae,Bang, Seong-Ae,Lee, Seung-Min,Kim, Sang-Un,Ko, Gil-Man,Lee, Kyung-Jae,Lee, In-Won 대한핵의학기술학회 2010 핵의학 기술 Vol.14 No.1
방사성핵종과 방사능을 측정하는 dose calibrator의 서로 다른 두개의 기기에서 F-18 FDG을 각각 측정하고, 이 측정값에 의한 인체 내 SUV (Standard Uptake Value)에 미치는 영향은 없는지에 대하여 알아보고자 하였다. 이 연구에서 두개의 다른 dose calibrator는 CRC-15 Dual PET, CRC-15R을 사용하였다. 각 dose calibrator에서 F-18 FDG를 2 mL 주사기 3개에 볼륨 1 mL, 2 mL, 3 mL를 만들어 각각 초기 radio activity를 측정한 후 4시간 30분(270분)까지 30분 간격으로 radio activity를 각각 측정하고 기록한다. 초기 radio activity 값을 기준으로 방사선붕괴 공식으로 산출된 값(decay factor)과 dose calibrator로 측정된 값 간의 직선성을 단순선형을 통하여 분석하였다. CRC-15 Dual PET에서 가장 이상적인 값에 가까운 측정값을 볼륨을 기준으로 하여, CRC-15R에서 측정된 값을 최적화하기 위한 선형회귀식을 회귀분석을 통하여 구한다. 선형회귀식의 산출값을 적용하여 PET/CT 검사를 시행한 50명을 대상으로 lung, liver, region 부위에 ROI을 그려 SUV를 구한다. CRC-15 Dual PET, CRC-15R에서 측정한 radio activity와 그 값을 이용한 SUV를 paired t-test로 통계적으로 유의한 차이가 있는지 알아보았다. CRC-15 Dual PET과 CRC-15R에서 측정한 radio activity의 상관분석결과 1 mL의 경우 상관성을 보여주는 r값은 r=0.999이었으며, 회귀분석에 위한 선형식은 y=1.0345x+ 0.2601이었다. 2 mL의 경우 r=0.999이며, 선형회귀식은 y=1.0226x+0.1669이었다. 3 mL의 경우 r=0.999이며, 선형회귀식은 y=1.0094x+0.1577이었다. 각 세 가지 볼륨에서 얻어진 선형회귀식의 산출 값을 이용하여 구한 lung, liver, region 부위에 ROI의 SUV에서의 차이는 1 mL의 경우, lung, liver, region은 (p<0.0001)로 t-test 결과 모두 유의한 차이가 있었다. 2mL의 경우, lung (p<0.002), liver, region은 ROI의 SUV에서 유의한 차이(p<0.0001)를 보였다. 또한 3 mL의 경우, lung(p<0.044), liver, region의 유의한 차이(p<0.0001)가 있었다. F-18 FDG 검사에서 사용되는 두 개의 dose calibrator CRC-15 Dual PET, CRC-15R의 radioactivity에 대한 측정치에서는 상관관계의 차이가 없다는 것을 알 수 있었다. 그러나 이 두 값을 통해 SUV는 인체 내의 uptake 정도에 있어서는 유의한 차이를 보인다는 것을 알 수 있었다. 따라서 이 두개의 dose calibrator를 사용함에 있어서, 이 두 값이 인체 내 SUV의 차이를 고려하여 사용하여야 할 필요성이 요구된다. Purpose: The purpose of this study is to measure F-18 FDG with two different types of dose calibrator measuring radionuclide and radioactivity and investigate the effect of F-18 FDG on SUV (Standard Uptake Value) in human body. Materials and Methods: Two different dose calibrators used in this study are CRC-15 Dual PET (Capintec) and CRC-15R (Capintec). Inject 1 mL, 2 mL, 3 mL of F-18 FDG into three 2 mL syringes, respectively, and measure initial radioactivity from each dose calibrator. Then measure and record radioactivity at 30 minute interval for 270 minutes. According to the initial radioactivity, linearity between decay factor driven from radioactive decay formula and the values measured by dose calibrator have been analyzed by simple linear regression. Fine linear regression line optimizing values measured with CRC-15 through regression analysis on the basis of the volume of which the measured value is close to the most ideal one in CRC-15 Dual PET. Create ROI on lung, liver, and region part of 50 persons who has taken PET/CT test, applying values from linear regression equation, and find SUV. We have also performed paired t-test to examine statistically significant difference in the radioactivity measured with CRC-15 Dual PET, CRC-15R and its SUV. Results: Regression analysis of radioactivity measured with CRC-15 Dual PET and CRC-15R shows results as follows: in the case 1 mL, the r statistic representing correlation was 0.9999 and linear regression equation was y=1.0345x+0.2601; in 2 mL case, r=0.9999, linear regression equation y=1.0226x+0.1669; in 3 mL case, r=0.9999, linear regression equation y=1.0094x+0.1577. Based on the linear regression equation from each volume, t-test results show significant difference in SUV of ROI in lung, liver, region part in all three case. P-values in each case are as follows: in 1 mL case, lung, liver and region (p<0.0001); in 2 mL case, lung (p<0.002), liver and region (p<0.0001); in 3 mL case, lung (p<0.044), liver and region (p<0.0001). Conclusion: Radioactivity measured with CRC-15 Dual PET, CRC-15R, dose calibrator for F-18 FDG test, do not show difference correlation, while these values infer that SUV has significant differences in the aspect of uptake in human body. Therefore, it is necessary to consider the difference of SUV in human body when using these dose calibrator.
축산물 및 가공 : 산란계 주령과 계란 난각 형태이상 정도가 내부품질에 미치는 영향
이재익 ( Jae Ik Lee ),이현정 ( Hyun Jung Lee ),김희수 ( Heui Soo Kim ),조철훈 ( Cheor Un Jo ),김선만 ( Sun Man Kim ),노재중 ( Jae Jung Noh ) 한국동물자원과학회 ( 구 한국축산학회 ) 2012 한국축산학회지 Vol.54 No.1
본 연구는 산란계의 주령 및 난각의 형태이상 및 이상 정도가 내부품질에 미치는 영향을 조사하기 위해 실시되었다. 동일 주령의 산란계 2계군에서 56주령부터 62주령 사이에 산란한 계란 21,000개 중 각 주별 1,000개를 무작위 추출하여 축산물품질평가사가 정상란과 형태 이상란을 구분하였다. 각각의 출현율과 할란검사를 실시하여 내부품질을 조사한 결과 전체적으로 정상란은 81.22%, 이상란은 18.78%의 출현율을 보였다. 주령의 증가에 따른 이상란의 출현율은 유의적인 차이를 보이지 않았으며(p>0.05), Haugh unit은 60주령이 56주령에 비해 높게 나타났으며 그 외에는 차이가 없었다. 동일 주령대를 비교했을 경우 난백고와 Haugh unit은 형태 이상란이 낮고 또한 이상의 정도가 심한 경우 더 낮게 측정되는 결과를 보였다(p<0.05). 특히 이상란 중 기형란의 난고와 Haugh unit이 현저하게 낮은 결과를 보여 이상란 중에서도 기형란이 내부품질이 가장 낮게 판명되었다. 결과를 종합해 보면 56~62주령 산란계로부터 생산된 계란의 외형적 이상은 내부품질의 저하와 밀접하게 상관한다고 볼 수 있으며, 현 계란 등급판정 체계에서 외관판정은 신선도 평가에 근거가 될 수 있을 것으로 보인다. This study was carried out to investigate the effects of age of laying hens and grade of shell abnormality on internal egg quality. At each week, 1,000 eggs were randomly selected from 21,000 eggs laid by Hy-Line hens(100,000 birds) aged from 56 to 62 wk. The samples were divided into normal and externally abnormal eggs by an official egg grader. Then, egg quality including egg weight, egg white height, Haugh unit and yolk color was evaluated from each normal and abnormal eggs. The production rate of externally normal and abnormal eggs was 81.22 and 18.78%, respectively. No difference found in the production rate by the increase of hen`s age, but Haugh unit of eggs from hens of 60-wk-old was higher(p<0.05) than that of 56-wk-old. When the same age groups were compared, egg white height and Haugh unit were lower in eggs which were externally abnormal. When the grade of abnormality increased, egg white height and Haugh unit were decreased further (p<0.05). Among the externally abnormal eggs, malformation showed the lowest Haugh unit. In conclusion, the shell abnormality of eggs laid by hens aged 56 to 62 wk was closely related with internal egg quality. Therefore, the grading external egg quality in the present egg grading system is directly related with the internal egg freshness.