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김윤홍,Kim, Yun-Hong 한국정보과학회 2001 정보과학회논문지 : 시스템 및 이론 Vol.28 No.4
본 논문에서는 조합논리회로의 테스트 컴팩션을 위한 두 가지 효율적인 알고리즘을 제안한다. 제안된 알고리즘들은 각각 동적인 컴팩션 기법과 정적인 컴팩션 기법을 사용하고 있으며, 실험을 위해 기존의 ATPG시스템인 ATALANTA에 통합 구현하였다. ISCAS85와 ISCAS89(완전스캔 버전) 벤치마크 회로에 대한 실험에서 본 시스템은 기존에 발표된 다른 컴팩션 알고리즘에 비하여 보다 작은 테스트 집합을 보다 빠르게 생성하였으며, 실험 결과를 통하여 제안된 알고리즘들의 유효성을 입증할 수가 있었다.
ATM망의 멀티미디어 데이터 처리를 위한 가입자단 플랫폼
김윤홍,손윤식,Kim Yunhong,Son Yoonsik 대한전자공학회 2005 電子工學會論文誌-SD (Semiconductor and devices) Vol.42 No.2
본 논문은 ATM 망에서 멀티미디어 데이터 서비스를 지원하기 위한 가입자단 플랫폼을 제안한다. AAL2 프로토콜, 스케줄러 알고리듬 등이 별도의 AAL2 프로세서로 설계되어 제안된 플랫폼은 AAL/ATM 관련 기능이 소프트웨어로 처리되던 기존 플랫폼에 비해 호스트 프로세서의 부하를 크게 줄일 수 있으며 ATM망을 통한 멀티미디어 데이터의 실시간 처리가 용이하게 하였다. 2중 타임 슬롯 링 구조를 적용한 ATS(Adaptive Time Slot) 스케쥴러는 VBR-rt, UBR, CBR 트래픽의 데이터 스케쥴링을 위한 효과적이고 간단한 방안을 제공한다 음성 압축 및 처리를 위하여 TI의 TMS320C5402 DSP를 적용하였고 AAL2 프로세서는 0.35 마이크론 공정에서 칩으로 제작되었다. VoDSL(Voice over DSL) 서비스를 위한 프로토콜을 구현하여 가입자 단말을 설계 제작하고 시험망에서 실험을 해 본 결과 $97\%$이상의 통화 성공율과 안정된 음성 서비스를 보장할 수 있음을 알 수 있다. In this paper, we propose a customer premise platform for processing multimedia data service on the ATM network. The proposed platform has a specific AAL2 processor that includes AAL2 protocol and scheduler algorithm so as to off-load large potion of burden from host processor and make it easy to process multimedia data from the ATM network in real time compared with conventional platform in which AAL/ATM tasks are processed by software. The ATS scheduler that is implemented based on 2-level time slot ring provides a simple and efficient method for scheduling data of VBR-rt, UBR and CBR traffics. TMS320C5402 DSP is used to process voice-related tasks such as voice compression and voice packet manupulation and AAL2 processor is implemented on $0.35\;{\mu}m$ process line. We implemented the customer premise equipment for VoDSL service and tested the proposed platform on a test bed network. The experimental results show that the proposed equipment has the call success rate of $97\%$ at least and provides voice service of toll-qualify.
Progression of diabetic nephropathy after successful pancreas transplantation alone: a case report
김윤홍,Dong Il Kim,Jae Ryong Shim,Tae Beom Lee,Kwang Ho Yang,Je Ho Ryu,Hyun Jung Lee,최병현 대한이식학회 2019 Korean Journal of Transplantation Vol.33 No.4
Pancreas transplantation is the only method that can nearly cure insulin-dependent diabetes mellitus. However, the effect of pancreas transplantation on patients with diabetic nephropathy has recently been considered controversial. In this report, we present a case of abrupt aggravation of proteinuria after successful pancreas transplantation alone without evidence of calcineurin inhibitor (CNI) toxicity. A 22-year-old female patient with type I diabetes mellitus underwent pancreas transplantation alone. The patient already had retinopathy and mild proteinuria, which in this case, may mean diabetic nephropathy. Her glucose levels were managed within the normal range after successful pancreas transplantation. However, the amount of proteinuria fluctuated. Kidney needle biopsy was performed owing to severe elevation of proteinuria, 2 years after the transplantation. Electron microscopy revealed diabetic glomerulosclerosis without evidence of CNI toxicity. This case indicates that diabetic nephropathy can be aggravated after pancreas transplantation, despite well-managed glucose levels and absence of CNI toxicity.
김윤홍,Ki Hyun Kim,서경원,Seung Hun Lee,Gyung Mo Son 대한내시경복강경외과학회 2022 Journal of Minimally Invasive Surgery Vol.25 No.1
Purpose: Incisional hernia is one of the most common complications after abdominal surgery conducted through a midline incision. Considerable debate remains regarding the design, comorbidity, suture material, and method. We investigated the risk factors for incisional hernia after laparoscopic colorectal surgery in the presence of limited surgery-related factors. Methods: A retrospective study was designed with 541 patients who underwent laparoscopic colorectal surgery performed by a single operator from January 2015 to December 2017. Due to open conversions, other abdominal operations, or follow-up loss, only 445 patients were included in the study. After propensity score matching, 266 patients were included. The study was based on diagnosis of incisional hernia on computed tomography at 6 and 12 months postoperatively. Results: Of the 266 total patients, 133 underwent abdominal closure using PDS (Ethicon), while the remaining 133 underwent closure with Vicryl (Ethicon). Of these patients, nine were diagnosed with incisional hernia at the 12-month follow-up: six (4.5%) in the Vicryl group and three (2.3%) in the PDS group (p = 0.309). The incidence of incisional hernia was significantly increased in females (odds ratio [OR], 15.233; 95% confidence interval [CI], 1.905–121.799; p = 0.010), in patients with body mass index (BMI) of >25 kg/m 2 (OR, 4.740; 95% CI, 1.424–15.546; p = 0.011), and in patients with liver disease (OR, 19.899; 95% CI, 1.614–245.376; p = 0.020). Conclusion: BMI of >25 kg/m 2 , female, and liver disease were significant risk factors for incisional hernia after elective laparoscopic colorectal surgery performed through a transumbilical minilaparotomy incision.
김윤홍,전경일,방기천,이우순,박인정,이강현,Kim, Yun-Hong,Jeon, Gyeong-Il,Bang, Gi-Cheon,Lee, U-Sun,Park, In-Jeong,Lee, Gang-Hyeon 대한전자공학회 2000 電子工學會論文誌-CI (Computer and Information) Vol.37 No.3
In this paper, we proposed the hardware architecture of wavelet transform digital filter for an image processing. Filter bank pyramid algorithm is used for wavelet transform and each fillet is implemented by the FIR filter. For DWT computation, because the memory controller is implemented by hardware, we can efficiently process the multisolution decomposition of the image data only input the parameter. As a result of the image Processing in this paper, 33㏈ PSNR has been obtained on 512$\times$512 B/W image due to 11-bit mantissa processing in FPGA Implementation. And because of using QMF( Quadrature Mirror Filter) properties, it reduces half number of the multiplier needed DWT(Discrete Wavelet Transform) computation so the hardware size is reduced largely. The proposed scheme can increase the efficiency of an image Processing as well as hardware size reduced. The hardware design proposed of DWT fillet bank is synthesized by VHDL coding and then the test board is manufactured, the operating Program and the application Program are implemented using MFC++ and C++ language each other. 본 논문에서는 영상처리를 위한 웨이브렛 변환 디지틀 필터 설계의 하드웨어 구조를 제안한다. 웨이브렛 변환을 위하여 필터 뱅크 피라미드 알고리즘을 이용하고 각각의 필터는 FIR 필터로 구현하였다. 그리고 메모리 제어기를 하드웨어로 구현하여 DWT 계산이 수행되므로 단순한 파라미터 입력만으로 영상 데이터의 다중해상도 분해를 효율적으로 처리할 수 있었다. 본 논문에서의 영상처리 결과는 FPGA의 하드웨어적 제한으로 인한 11bit의 가수처리 때문에, 512×512 흑 백영상에 대하여 33㏈의 PSNR이 나타났다. 그리고 QMF(Quadrature Mirror Filter)의 특성을 이용하여 DWT(Discrete Wavelet Transform) 계산에 필요한 승산기의 수를 절반으로 줄임으로써 하드웨어의 크기도 감소하였다. 그러므로 제안된 방법은 하드웨어 크기의 감소에 따른 영상처리의 효율성을 증대할 수 있다. DWT 필터 뱅크의 제안된 하드웨어 설계는 VHDL 코딩으로 설계합성을 하여 테스트 보드가 제작되었으며, 실행프로그램은 MFC++로, 영상복원 디코드 응용프로그램은 C++언어를 이용하여 구현하였다.
실험연구 : 쥐 배아심장 H9c2세포의 허혈 후 재산소화 시 Propofol 농도가 활성산소 발생에 미치는 영향
김윤홍 ( Yun Hong Kim ),김현수 ( Hyun Soo Kim ),이영재 ( Young Jae Yi ),최원준 ( Won Joon Choi ),송준규 ( Jun Kyu Song ),이선민 ( Seon Min Lee ),최원재 ( Won Chae Choe ),김성수 ( Sung Soo Kim ) 대한마취과학회 2006 Korean Journal of Anesthesiology Vol.51 No.1
Background: Reoxygenation of an ischemic heart causes a decrease in the cardiac function, which is known as reperfusion injury that is associated with an increase in the concentration of reactive oxygen species (ROS). This study examined the effect of the propofol concentration on the generation of ROS during reoxygenation in rat embryonic heart H9c2 cells. Methods: Cultured H9c2 cells were examined in the following sequences: Prehypoxic, Hypoxic and Reoxygenation period. Each period required 60 minutes. The cells were exposed to propofol at the beginning of the prehypoxic period. Thirty minutes later, DCFH-DA (dichlorofluorescin diacetate) 10μM was added to detect the ROS. The propofol concentrations used were 0, 5, 25, 50, 250μM in the first experiment and 0, 1, 2, 3, 4, 5μM in the second experiment. The ROS level was estimated using a fluorometer at 5-minute intervals from 5 to 60 minutes after reoxygenation. Results: When the propofol concentrations was > 5μM, the ROS levels were significantly lower than those of the untreated group (P0) (P < 0.05). At propofol concentrations < 5μM, the ROS levels 35 to 60 minutes after reoxygenation were significantly lower that in the untreated group (P < 0.05). Between 5 and 30 minutes after reoxygenation, the cells exposed to 1, 4 and 5μM propofol also showed lower ROS levels than the untreated group P0. However, 2 and 3μM propofol did not show any significant difference in ROS values to those observed in the untreated group except for 2μM at 25 minutes after reoxygenation. Conclusions: During the reoxygenation period in H9c2 cells, propofol concentrations > 5μM inhibited ROS production over the whole period, and even 1μM showed some inhibition of ROS. (Korean J Anesthesiol 2006; 51: 89~93)
복강경 보조하 질식 자궁절제술을 받은 환자에서 Remifentanil을 이용한 술 후 자가통증조절에 대한 연구
김윤홍 ( Yun Hong Kim ),문성하 ( Sung Ha Mun ),김현수 ( Hyun Su Kim ),우철호 ( Chul Ho Woo ),김용찬 ( Yong Chan Kim ) 대한마취과학회 2009 Korean Journal of Anesthesiology Vol.56 No.1
Background: This randomized, double-blinded clinical study was designed to compare the efficacy and safety of three regimens of intravenous (IV) patient-controlled analgesia (PCA) with remifentanil for postoperative analgesia after laparoscopic-assisted vaginal hysterectomy during the first 24 postoperative hours. Methods: Thirty-four patients were randomly allocated into three groups. The first group received IV remifentanil PCA at a basal rate of 0.02 μg/kg/min, a bolus of 0.3 μg/kg, and a lockout time of 15 min. The second group received IV-PCA at a basal rate of 0.025 μg/kg/min, a bolus of 0.375 μg/kg, and a lockout time of 15 min. The third group received IV-PCA at a basal rate of 0.03 μg/kg/min, a bolus of 0.45 μg/kg, and a lockout time of 15 min. Age, weight, height, and duration of surgery and anesthesia were recorded. Heart rate, systolic and diastolic blood pressure (BP) and oxygen saturation by pulse oxymetry were recorded in the recovery room as a base line after the operation. Heart rate, systolic and diastolic BP, sedation score, visual analogue scale (VAS), and postoperative nausea and vomiting (PONV) scores were recorded at 1 h, 3 h, 6 h, 12 h, and 24 h after the initiation of IV-PCA. Results: Thirty two patients were evaluated. The VAS in group 1 at 1, 3 and 6 hours after surgery was significantly higher than in other groups (P<0.05). There were no clinically relevant differences between the groups in PONV, sedation scores, or hemodynamic parameters. Conclusions: This study suggests that IV remifentanil PCA with at a basal rate of 0.025 μg/kg/min (group 2) provided efficacious analgesia after laparoscopic-assisted vaginal hysterectomy. Special attention must be given to respiratory depression during establishment of PCA with remifentanil. (Korean J Anesthesiol 2009;56:54~9)
한국인 Gilbert`s syndrome 환자에서 UGT-1A1 promoter 유전자 다양성에 관한 연구
김윤홍 ( Yoon Hong Kim ),정길만 ( Gil Man Gung ),김효정 ( Hyo Jung Kim ),장윤정 ( Yun Jung Chang ),연종은 ( Jong Eun Yeon ),김재선 ( Jae Seon Kim ),변관수 ( Kwan Soo Byun ),박영태 ( Young Tae Bak ),이창홍 ( Chang Hong Lee ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<목적> Gilbert`s syndrome은 다른 원인없이 간헐적인 unconjugated bilirubin의 증가를 보이는 질환으로서 bilirubin을 conjugation 시켜 배설시키는 UGT-1A1의 활성도가 정상인의 30% 정도로 떨어져서 발생하는 것으로 알려져 왔다. 지금까지 알려진 바에 의하면 정상적인 서구인의 경우 UGT-1A1의 promotor의 일정부위가 정상적인 (TA)6를 이루는데 비해 Gilbert`s syndrome 환자의 경