Eugene O’Neill에 나타난 神話

金容德(Yong dug Kim) 새한영어영문학회 1980 새한영어영문학 Vol.9 No.-

수확시기별 제주재래종 감귤과피의 활성산소종 소거활성

김용덕(Yong-Dug Kim),마힌다(Senevirathne Mahinda),고경수(Kyung-Soo Koh),전유진(You-Jin Jeon),김수현(Soo-Hyun Kim) 한국식품영양과학회 2009 한국식품영양과학회지 Vol.38 No.4

제주재래종 감귤류 10종에 대해서 수확시기별 총 폴리페놀 함량과 활성산소종 소거활성 변화를 조사하였다. 총 폴리페놀 함량은 지각과 홍귤이 미숙과인 8월 하순과 9월 하순에 200 ㎎% 내외로 가장 높았고 대부분의 감귤종이 수확시기가 늦어질수록 감소하는 경향을 보였다. 수확시기별 감귤과피의 superoxide anion radical 소거활성은 홍귤과 지각에서 60% 이상으로 가장 높았고 사두감이 가장 낮은 활성을 보였으며 홍귤과 지각을 제외한 감귤류의 수확시기별 차이는 크지 않았다. Hydrogen peroxide 소거활성은 8월 하순에 사두감이 73.8%로 가장 높은 소거활성을 나타내었고 그 다음에 지각이 거의 70%의 소거활성을 보였으며, 대부분의 감귤종이 수확시기가 늦어질수록 감소하는 경향을 보였다. Hydroxy radical 소거활성은 대부분의 재래감귤종의 과피에서 비교적 높은 활성을 보였으며 지각과 당유자가 8월 하순에 각각 75.1%와 74.6%로 가장 높은 소거활성을 보였고, 그 외 감귤종도 60% 이상의 소거능을 보였으며 수확시기별 차이는 거의 없었다. 감귤이 성숙됨에 따라 hydrogen peroxide 소거능, superoxide anion 라디칼 소거능은 감소하는 경향을 보이나 nitric oxide 라디칼 소거활성은 증가하는 추세를 보였고, 병귤이 58.4%로 가장 활성이 높았으며 다른 활성산소종에서 활성이 높았던 사두감, 지각, 당유자가 활성이 가장 낮았다. 본 실험결과 제주재래종 감귤 중 특히 지각이 대부분의 활성산소종에 높은 소거활성을 보였으며, 이에 대한 구체적인 연구가 진행될 필요성이 있을 것으로 판단된다. This study was conducted to investigate total polyphenolic contents and reactive oxygen species (ROS) scavenging effects of extracts from peels of ten Jeju native citrus fruits according to the harvest from August 2006 to February 2007. Total polyphenolic contents from methanol extracts of citrus peel were the highest in Jigak (Citrus aurantium) and Hongkyool (C. tachibana) by over 200 ㎎% in the unmatured period, from the late August to the late September, and all the citrus peels mostly decreased while ripening. Scavenging effect of superoxide anion radical showed good correlation with total polyphenolic contents. The unmatured periods of Hongkyool and Jigak were the highest with more than 60%. Hydrogen peroxide scavenging activity was the highest in Sadoogam (C. pseudogulgul) at 73.8% in late August and the second highest activity was observed in Jigak at near 70%, and all the citrus peels decreased during ripening. Hydroxy radical scavenging activity were the highest among all the ROS scavenging activities, especially in the Jigak and Dangyooja (C. grandis) at 75.1% and 74.6%, respectively, and not much affected by increased maturity of the fruits. Nitric oxide radical scavenging activity was the highest in Bungkyool (C. platymama) at 58.4% in late February, and increased with fruit ripening. In this study, Jigak was generally the highest in the polyphenolic contents and ROS scavenging activities, so the further studies are needed for industrial applications.

수확시기별 제주재래종 감귤착즙액의 Flavonoids 분포 및 항산화 활성

김용덕(Kim Yong Dug),고원준(Ko Weon Jun),고경수(Koh Kyung Soo),전유진(Jeon You Jin),김수현(Kim Soo Hyun) 韓國營養學會 2009 Journal of Nutrition and Health Vol.42 No.3

제주재래종 감귤류 14종의 착즙액에 대해서 수확시기별 flavonoids 13종의 함량변화를 분석하고 항산화성을 검토하고자 하였다. 감귤착즙액의 flavonoids 함량은 수확시기가 늦어질 수록 큰 폭으로 감소하다가 4~5차 채취기 이후 서서히 증가하는 경향을 보였다. Quercatagetin, narirutin, hesperidin, neohesperidin은 각각 지각 573.73 ㎎/100 ㎖, 사두감 393.99 ㎎/100 ㎖, 소유자 29.63 ㎎/100 ㎖, 지각 201. 23 ㎎/100 ㎖으로 미숙과인 8월 하순에 가장 높았다. Polymethoxyflavone류 중 nobiletin, sinensetin, tangeretin은 홍귤에서 8월 하순에 각각 7.39 ㎎/100 ㎖, 2.24 ㎎/100 ㎖, 0.63 ㎎/100 ㎖으로 가장 높았고, 다음으로 진귤이 많이 함유되어 있었다. 3,5,6,7,8,3',4'-Heptamethoxyflavone은 편귤에서 0.27 ㎎/100 ㎖으로 가장 높았고, 3',4',7,8-tetramethoxyflavone, 3',4'-dimethoxyflavone, 4'-methoxyflavone, 5,6,7,3',4',5'-hexamethoxyflavone, scutellarein tetramethylether는 모든 품종에서 ND~0.08 ㎎/100 ㎖로 함량이 낮았다. 총 폴리페놀 함량은 대부분의 시료가 미숙과인 8월 하순에 가장 높았다가 11월까지 감소하다가 12월 하순부터 증가하는 경향을 보였다. 감귤착즙액의 전자공여능은 대체적으로 높은 것으로 나타났으나 flavonoids와 총폴리페놀 함량과의 상관관계는 높지 않은 경향을 보였고 당유자가 가장 높은 항산화활성을 나타내었다. 재래 감귤류 중 지각, 당유자는 quercetagetin이 다른 감귤류에 비해 월등히 높았고, polymethoxyflavone류인 nobiletin과 tangeretin은 미숙과인 홍귤과 진귤에서 함량이 높아 소재 개발로서 경쟁력이 있을 것으로 사료된다. This study aims to evaluate the changes of flavonoid contents and antioxidants activity of Jeju native citrus fruits juice according to the harvest date. Flavonoids such as quercatagetin, narirutin, hesperidin and neohesperidin were contained most plentifully in the juice of Jigak (Citrus aur- antium) by 573.73 ㎎/100 ㎖, Sadoogam (C. pseudogulgul) by 393.99 ㎎/100 ㎖, Soyooja by 29.63 ㎎/100 ㎖ and Jigak (C. aurantium) by 201.23 ㎎/100 ㎖ in the late August, respectively. The highest contents of nob-iletin, sinensetin and tangeretin among polymethoxyflavones were found in the juice of Hongkyool (C. tachibana) by 7.39 ㎎/100 ㎖, 2.24 ㎎/100 ㎖, 0.63 ㎎/100 ㎖ in the late August, respectively. 3,5,6,7,8,3’,4’- Heptamet- hoxyflavone recorded the highest amount in Punkyool (C. tangerina) by 0.27 ㎎/100 ㎖ in the late August, but the other polymethoxyflavones including 3’,4’,7,8-tetramethoxyflavone, 3’,4’-dimethoxyflavone, 4’-methoxyflavone, 5,6,7,3’,4’,5’-hexamethoxyflavone, scutellarein tetramethylether were observed only trace amount in all the citrus fruits. Flavonoid contents in the citrus fruit juices were the highest during early maturation and decreased rapidly while ripening. Total polyphenol contents were the highest in the late August and decreased with ripening. However from the late December, the contents were increased again. Antioxidant activities of the fruits were evaluated as electron donating ability and were the lowest in the late September and increased with the fruit ripening. These results suggest that quercetagetin among all the flavonoids was most plentiful in Jigak and Dangyooja (C. grandis), so that the fruits could be used for industrial material of flavonoids and antioxidant agents.

췌십이지장 절제술에서 위 및 유문부 보존술식

김용덕(Yong Dug Kim),문덕진(Doug Jin Moon),박주섭(Ju Sup Park) 대한외과학회 1987 Annals of Surgical Treatment and Research Vol.32 No.4

담관낭종에 대한 임상적 고찰

김용덕(Yong Dug Kim),서영석(Young Seok Seo),강대석(Dae Suk Kang),박주섭(Joo Sup Park) 대한외과학회 1987 Annals of Surgical Treatment and Research Vol.33 No.6

드론의 원격제어 및 관제 모니터링 소프트웨어 개발

이찬수(Lee Chan Su),정세벽(Jeong Se Byeok),맹정현(Maeng Jung Hyun),난딘자야(Enkhmandakh Nandinzaya),정설영(Jeong Seol Young),김용덕(Kim Yong Dug) 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.11

상소뇌동맥 연변분지 기시부에서 발생한 뇌동맥류 : 1예 보고 A Case Report

김용덕,윤일규,도재원,배학근,이경석,변박장 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.12

The authors pmmt a case of non-mymtic aneuIysm arising h m the m a r g ~ ~ I branch of the left superior cetebellar artery(SCA) in a 65-year-dd female. Cerebral angiography disclosed a saccular aneurysm(3X3mm) at the origin of marginal branch of the left SCA. Tbe aneurysm was sucuddy clipped through the infratentorialapracerebellar approach. Since the aneurysm from the marginal branch of the SCA is rare, we report here brieily.

요추간판탈출증에 대한 경피적 자동수핵 제거술의 임상적 분석

김용덕,신원한,최순관 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

..

요추간판탈출증에 대한 경피적 자동수핵제거술의 임상적 분석

신원한,김용덕,김범태,최순관,변박장 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.9

A retrospective study of operative results was carried out in a serics of 48 patients who were performed automated percutaneous discectomy for herniated lumbar disc using Nucleotome between Jan.1990 and Jan.1994. The operative results were analysed, and the correlation between preoperative clinicoradiological factors and postoperative clinical results were statistically assessed. The major results were as follows : 1) Of 48 patients, 37 were males and 11 were females. Mean age of the patients was 31.7 years and the highest incidence occurred in their thirties. 2) The preoperative symptoms and signs were radiating pain(l00%), lumbago(94%), motor weakness(21%), and positive score in straight leg raising test(77%). Mean duration of symptoms was 33.1 months and the duration of recent aggravation was 3.7 months. 3) Operation was performed in 62 intervertebral discs, the most commonly involved level was L4-5 (53%). Mean duration of follow-up was 19.1 months. 4) Clinical results on follow-up were graded excellent in 65%, good in 21%, fair 8% and poor in 6% by Cabot's classification, and the overall success rate was 85% by Onik's classification. 5) As to age distribution and the group concerning compensatory and non-compensatory, success rates were not statistically significant. 6) The causes of failure were sequestered discs in 3 cases, suspicious sequestered discs in 2 cases, combined spinal stenosis with multiple discs in 1 case and worker's compensation in 1 case. According to the above results, automated percutaneous discectomy was recommended as primary choice of a relatively noninvasive surgical procedure for the herniated lumbar discs except for sequestered disc and spinal stenosis.

요추간판탈출증과 동반된 Conjoined Nerve Root Anomaly : 증례보고 A Case Report

윤석만,신원한,김용덕,김범태,최순관,변박장 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.2

The condition of anomalous nerve root is rare. The authors are reporting a case of conjoined nerve root anomaly associated with lumbar disc herniation in a 36-year-old male who was transferred from another hospital. A standard hemilaminectomy with a discectomy had been performed under the diagnosis of the L4-5 lumbar disc herniation at the other hospital. However symptoms were not relieved. During a second surgery at our hospital, a L5-S1 conjoined nerve root was discovered after removal of the extradural hematoma at the previous laminectomy site, a medial facetectomy with a foraminotomy were carried out and the conjoined root was decompressed completely. The patient returned to work 2 months postoperatively with complete relief of symptoms.