성인의 턱관절장애 자각증상에 영향을 미치는 요인

김수경,김소라,김현경,박지수,이유진,조민서,정은서,Kim, Soo-Kyung,Kim, So-Ra,Kim, Hyun-Kyung,Park, Ji-Su,Lee, Yu-Jin,Cho, Min-Seo,Jung, Eun-Seo 한국치위생학회 2017 한국치위생학회지 Vol.17 No.4

Objectives: The purpose of this study is to identify the perceived symptoms of oral and temporomandibular joint disorders in adults and to analyze the factors affecting subjective symptoms of temporomandibular joint disorders. Methods: 249 adults over 20 years old who had subjective symptoms of temporomandibular joint disorders were surveyed and analyzed. Independent t-test and ANOVA test were used to examine the relationship between oral habits and temporomandibular joint disorder according to general characteristics. $Scheff{\acute{e}}$ test was used for post-hoc analysis. Multiple regression analysis was conducted to examine the factors affecting oral habits and temporomandibular joint disorder. Results: First, the factors affecting oral and habitual behaviors were married (p<0.05) and monthly income between 1 million~1.9 million won (p<0.001), higher temporomandibular joint disorder (p<0.01) And the degree of habit was increased. Second, the factors affecting temporomandibular joint disorder were increased in occupation (p<0.05) and the degree of oral habit (p<0.01). Conclusions: In conclusion, it was confirmed that oral habit influences temporomandibular joint disorder. Especially, it is suggested that prevention and promotion of temporomandibular joint disorder are needed to recognize the removal of oral habits.

백서두개골 결손부에서 키토산/흡수성 콜라겐 전달체의 골재생

김수경,석헌주,김창성,조규성,채중규,김종관,최성호,Kim, Soo-Kyoung,Suk, Hun-Joo,Kim, Chang-Sung,Cho, Kyoo-Sung,Chai, Jung-Kiu,Kim, Chong-Kwan,Choi, Seong-Ho 대한치주과학회 2003 Journal of Periodontal & Implant Science Vol.33 No.3

The ultimate objective of periodontal treatment is to get rid of an on-going periodontal disease and further regenerate the supporting tissue, which is already destroyed, functionally. Currently, the bone grafting operation using various kinds of bone grafting materials and the operation for induced regeneration of periodontal tissue using the blocking membrane are performed for regeneration of the destroyed periodontal tissue. However, there are respective limitations Galenical preparations, which are used for regeneration of periodontal of tissue, has less risk of rejective reaction or toxicity that may be incidental to degradation and their effect is sustainable. Thus, in case they are applicable to a clinic, they can he used economically. Chitosan has such compatibility, biological actions including antibacterial activity, acceleration of wound treatment, etc., and excellent mechanical characteristics, which has recently aroused more interest in it. Also, it has been reported that it promotes osteogenesis directly or indirectly by functioning as a matrix to promote migration and differentiation of a specific precussor cell (for example, osteoblast) and further inhibiting the function of such a cell as fibroblast to prevent osteogenesis. In this study, the pure chitosan solution, which was obtained by purifying chitosan, was used. However, since this chitosan is of a liquiform, it is difficult to sustain it in a defective region. It is, therefore, essential to use a carrier for delivering chitosan to, and sustaining it gradually in the defective region. In the calvarial defect model of the Sprague-Dawley rat, it is relatively easy to maintain a space. Therefore, in this study, the chitosan solution with which ACS was wetted was grafted onto the defective region, For an experimental model, a calvarial defect of rat m s selected, and a critical size of the defective region was a circular defect with a diameter of 8 mm. A group in which no treatment was conducted for the calvarial defect was set as a negative control group. Another group in which treatment was conducted with ACS only was set as a positive control group (ACS group). And another group in which treatment was conducted was conducted with by grafting the pure chitosan solution onto the defective region through ACS which was wetted with the chitosan solution was set an experimental group (Chitosan/ACS group). Chitosan was applied to the Sprague-Dawley rat's calvarial bone by applying ACS which was wetted with the chitosan solution, and each Sprague-Dawley rat was sacrificed respectively 2 weeks and 8 weeks after the operation for such application. Then, the treatment results were compared and observed histologically and his tometrically. Thereby, the following conclusions were obtained. 1. In the experimental group, a pattern was shown that from 2 weeks after the operation, vascular proliferation proceeded and osteogenesis proceeded through osteoblast infiltration, and at 8 week after the operation, ACS was almost absorbed, the amount of osteogensis was increased and many osteoid tissue layers were observed. 2. At 2 weeks after the operation, each amount of osteogenesis appeared to be 8.70.8 %, 13.62.3 % and 4.80.7 % respectively in the experimental group, the positive control group and the negative control group. Accordingly, it appeared to be higher in the Experimental group and the positive control group than in the negative control group, but there was no significant difference statistically (p<0.01). 3. At 8 weeks after the operation, each amount of osteogenesis appeared to be 62.26.1%, 17.42.5 % and 8.21.4 % respectively in the experimental group, the positive control group and the negative control group. Accordingly, it appeared to be substantially higher in the experimental group than in the positive control group and the negative control group, and there was a significant difference statistically (p<0.01). As a result of conducting the experiment, when ACS

한국인의 Epstein-Barr Virus 항체 양성률 변화양상에 대한 분석: 단일기관 연구

김수경,최준식,김동섭,강철인,정두련,백경란,강은숙,김예진,Kim, Su Kyung,Choi, Joon-Sik,Kim, Dongsub,Kang, Cheol-In,Chung, Doo Ryeon,Peck, Kyong Ran,Kang, Eun-Suk,Kim, Yae-Jean 대한소아감염학회 2020 Pediatric Infection and Vaccine Vol.27 No.2

Purpose: Epstein-Barr virus (EBV) infection is related to infectious mononucleosis or nasopharyngeal cancer, and its epidemiology may change according to the socioeconomic development of communities. This study aimed to evaluate the recent epidemiology of EBV seropositive rate in Korea. Methods: We retrospectively reviewed EBV serology test results obtained from a part of clinical care at Samsung Medical Center, Seoul, South Korea, from January 2000 to December 2017. Results: The EBV seropositive rate in 26,527 subjects during the study period was 81.0% (21,485/26,527): 44.4% (2,716/6,122) in subjects aged 0-9 years, 75.8% (2,077/2,739) in those aged 10-19 years, and 94.5% (16,692/17,666) in those aged ≥20 years. The EBV seropositive rate decreased from 89.4% (8,592/9,616) in 2000-2008 to 76.2% (12,893/16,911) in 2009-2017 (P<0.001). Especially, the EBV seropositive rate in subjects aged 0-19 years significantly decreased from 2000-2008 to 2009-2017 (0-9 years, 62.8% [1,172/1,866] in 2000-2008 and 36.3% [1,544/4,256] in 2009-2017; 10-19 years, 83.8% [745/858] in 2000-2008 and 70.8% (1,332/1,881) in 2009-2017) (P<0.001). Conclusions: The EBV seropositive rate in children has decreased in the last 20 years. As the age of patients with primary EBV infection increased, there is a need for interest in clinical manifestation, such as infectious mononucleosis, in adolescents and young adults.

가수량을 달리한 쌀밥의 저장에 따흔 특성변화

김수경,신말식,Kim, Su-Gyeong,Sin, Mal-Sik 한국식품조리과학회 1992 한국식품조리과학회지 Vol.8 No.2

Quorum sensing 결핍 세균에서 생물막 형성의 시간적 추이 분석

김수경,이미난,이준희,Kim, Soo-Kyoung,Lee, Mi-Nan,Lee, Joon-Hee 한국미생물학회 2014 미생물학회지 Vol.50 No.2

녹농균(Pseudomonas aeruginosa)과 비브리오 불니피쿠스균(Vibrio vulnificus)은 그람 음성의 병원균들로써, quorum sensing(QS) 기전을 통해 병원성을 발현하는 세균들이다. 이들 병원균의 감염은 많은 경우 생물막 형성에 의해 매개된다고 알려져 있는데, 이에 본 연구에서는 P. aeruginosa와 V. vulnificus를 대상으로 QS 기전의 유무에 따른 생물막 형성의 시간적 추이를 분석해 보았다. 그 결과 P. aeruginosa의 경우 QS 기전이 결핍된 균주가 야생형에 비해 초기 부착은 더 잘 하였으나, 이후 생물막 구조의 성숙 능력은 야생형에 비해 현저히 떨어짐을 알 수 있었다. 이러한 특성 때문에 야생형과 QS 결핍 균주의 생물막 형성을 시간의 추이에 따라 정량적으로 비교해 보면 초기 10시간 정도 까지는 QS 결핍 균주가 더 많은 생물막을 형성하다가, 이후 야생형이 더 많이 생물막을 형성하는 역전 현상이 관찰되었다. V. vulnificus는 P. aeruginosa와는 달리 QS 결핍 균주가 야생형보다 더 많은 생물막을 형성한다고 보고된 균주이다. 이 균주에서 같은 방식으로 생물막 형성을 조사해 본 결과, 108시간의 장시간 동안에도 항상 QS 결핍 균주가 야생형 보다 더 많은 생물막을 형성하여, 역전 현상은 관찰되지 않았다. 이 결과는 P. aeruginosa의 경우에는 QS 기전이 초기 부착은 저해하는 방향으로, 성숙과정은 촉진시키는 방향으로 작용하며, V. vulnificus에서는 일관되게 생물막 형성을 저해하는 방향으로 작용함을 보여주는 것이다. 따라서 생물막 제어를 위한 타겟으로 QS기전을 이용할 때에는 제어하고자 하는 생물막 형성 단계와 세균 종을 함께 고려하여야 한다고 제안한다. Pseudomonas aeruginosa and Vibrio vulnificus are Gram-negative human pathogens, which exert their virulence through quorum sensing (QS) regulation. The infection of these pathogens have been known to be mediated by biofilm formation in many cases and this study carried out the time-course analysis of biofilm formation depending on the QS regulation in P. aeruginosa and V. vulnificus. In P. aeruginosa, our results demonstrated that QS-deficient mutant better attached to surface at initial stage of biofilm formation, but poorly proceeded to the maturation of the biofilm structure, while wild type less attached at initial stage but developed highly structured biofilm at late stage. Because of this, the quantitative comparison of biofilm formation between wild type and the QS mutant showed the reversion; the QS mutant formed more biofilm until 10 h after inoculation than wild type, but wild type formed much more biofilm after 10 h than QS mutant. V. vulnificus has been reported to form more biofilm with the mutation on QS system. When we performed the same time-course analysis of the V. vulnificus biofilm formation, the reversion was not detected even with prolonged culture for 108 h and the QS mutant always forms more biofilm than wild type. These results indicate that the QS regulation negatively affects the attachment at early stage but positively facilitates the biofilm maturation at late stage in P. aeruginosa, while the QS regulation has a negative effect on the biofilm formation throughout the biofilm development in V. vulnificus. Based on our results, we suggest that the developmental stage of biofilm and bacterial species should be considered when the QS system is targeted for biofilm control.

세미나 지상중계 - 대학교육 정책포럼 개최, 대입제도의 선진화 방안 탐색

김수경,Kim, Su-Gyeong 한국대학교육협의회 2009 大學敎育 Vol.162 No.-

(정신건강과 자아발달을 돕는) 체험적 독서치료

김수경,Kim, Su-Gyeong 한국도서관협회 2008 圖協會報 Vol.49 No.4

제29회 대학교육 정책포럼

김수경,Kim, Su-Gyeong 한국대학교육협의회 2010 大學敎育 Vol.168 No.-

Peroxidase 고생산 식물세포주의 선발

김수경,곽상수,정경희,민성란,박일현,유장렬 ( Soo Kyung Kim,Sang Soo Kwak,Kyung Hee Jung,Sung Ran Min,Il Hyun Park,Jang R. Liu ) 생화학분자생물학회 1994 BMB Reports Vol.27 No.2

To establish an efficient system for peroxidase (POD) production by plant cell culture, we investigated the POD activity in 41 cell lines derived from 26 plant species using pyrogallol as substrate. A cell line from sweet potato (Ipomoea batatos cv. White Star) shoot meristem explants cultured on LS medium supplemented with 1 ㎎/ℓ 2,4-D showed the highest activity: 3,500 U/g cell dry wt, about 15 folds higher than that of intact roots of horseradish plants. Furthermore, a cell tine SP-47 having a high growth rate and POD yield was selected by a small cell-aggregate method, of which productivity was about 1.5 times higher than the original cell line in cell suspention culture. A hairy root culture obtained from sweet potato leaf tissue following infection with Agrobacterium rhizogenes strain 15834 also produced a high level of POD: 1,400 U/g dry wt. POD isoenzyme of the cell line and hairy roots of sweet potato showed the same patterns as those of the intacts roots. However, they were prominently different from those of intact roots of horseradish. One major isoenzyme of POD in SP-47 and hairy root covered about 90% of total POD. Due to its high productivity and dominant major isoenzyme, the cell culture system of sweet potato established in this study seems to be suitable for the mass production of POD.

가미쌍화탕과 양의공진단 투여로 호전된 양하지 속 상연축 환자 1례

김수경,여서원,이현중,이동혁,두경희,조승연,박성욱,고창남,박정미,Kim, Soo-Kyung,Lu, Hsu-Yuan,Lee, Hyun-Joong,Lee, Dong-Hyuk,Doo, Kyeong-Hee,Cho, Seung-Yeon,Park, Seong-Uk,Ko, Chang-Nam,Park, Jung-Mi 대한중풍순환신경학회 2014 대한중풍.순환신경학회지 Vol.15 No.1

■ Objectives This clinical study is to report the effect of Korean medicine on patient with chronic benign fasciculation syndrome on a both legs. ■ Methods A patient who suffered from involuntary fasciculation of Quadricepts femoris and Gastrocnemius was treated with herbal medicine Gami SSanghwa-Tang and Yang Eui Gongjin-dan, acupuncture and moxibustion. Degree of fasciculation and general condition was measured. ■ Results After taking Gami Ssanghwa-Tang and Yang Eui Gongjin-Dan, degree of fasciculation have reduced and patient's general condition improved. ■ Conclusion This clinical case study showed the effect of Korean medicine on symptom of fasciculation.