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슬래그의 미세구조 및 화학분석을 통한 6-7세기 한국의 청동 야금 기술 연구
김소진,한우림,문동혁,이나라,김영도 대한금속·재료학회 2022 대한금속·재료학회지 Vol.60 No.10
Metallurgical remains such as crucible, mould, slag and tuyere are generated in the production of bronze. The analysis of slag in particular can be used to identify the raw materials, processes and environments (temperature and condition) employed in the bronze fabrication . The Gwanbuk-ri site in Buyeo is known as the location of a royal palace during the Baekje period, in the 6-7th centuries, and crucible fragments and slags used to make bronze were excavated there. The purpose of this study is to understand the process of bronze production and the origin of the raw ores used in the Baekje period, through micro-structure and microchemical analyses. Using chemical analysis and observation of the microstructure of the crucible and slag samples, we identified evidence of the bronze alloying and melting conditions. The melting process would have taken place under a variable redox atmosphere at 1,100 oC. Cu-Sn-Pb ternary bronze might have been produced by alloying Cu-Sn metal with lead ore (galena) in the Baekje period. The lead isotope composition ratios of 2 bronze slags were located in zone 2 and zone 3 of the lead isotope map in the southern Korean peninsula, which indicates the use of galena from south Chungcheong and north Gyeongsan provinces. For efficiency and costeffectiveness, a concentrate of lead ore might have been transported from the mine to the consumer site.
김소진,Kim, So-Jin 한국주택협회 2007 주택과 사람들 Vol.202 No.-
정부가 준비 중인 분당급 신도시의 입지가 오는 6월 확정될 예정이어서 수요자들의 관심이 높아지고 있다. 1980년대 말 강남권의 수요 흡수와 집값 안정 대책으로 개발됐던 분당의 닮은꼴이 과연 어디가 될지 자못 궁금해진다.
김소진,Kim, So-Jin 한국주택협회 2006 주택과 사람들 Vol.189 No.-
남태평양의 피지, 괌, 오스트레일리아, 뉴질랜드와 함께 세계적인 관광 휴양지로 각광받고 있는 하와이(Hawaii). 2~3년 전부터 새로운 전환점을 맞은 하와이의 주택, 리조트 시장의 현장속으로 들어가보자.
김소진,Kim, So-Jin 한국주택협회 2006 주택과 사람들 Vol.189 No.-
현대인들은 바쁘고 정신없다는 말을 자주 쓴다. 생활환경 속 소음이 스트레스 가중시키고 집중력을 저하시키는 등 일상생활에 방해가 되는 경우가 많다. 환경부가 발표한 생활 소음 저감 대책에 대한 내용들에 대해 알아보자.
김소진,Kim, So-Jin 한국주택협회 2007 주택과 사람들 Vol.203 No.-
전 세계적으로 초고층 빌딩 건축 붐이 일고 있다. 여러 나라들은 세계에서 가장 높은 빌딩을 지어 도시의 경쟁력과 국가의 위상을 높이려는 노력을 계속하고 있다. 국내에도 초고층 빌딩 건립을 위한 프로젝트가 상당수 진행되고 있다. 하지만 이들 프로젝트들은 법적 문제를해결하고 이해 관계를 조율해야 하는 등 난관에 봉착했다. 해외 초고층 건축물의 역사와 함께 국내 초고층 빌딩 건축의 현주소를 살펴보았다.
Cemental Tear: Radiographic-clinical characteristics and its Predisposing factors
김소진,강병철,김선헌,정현주 대한구강해부학회 2019 대한구강해부학회지 Vol.40 No.1
Root surface integrity is essential for periodontal health. The cemental tears (CETs) were more likely to have periodontal bone destruction and the treatment outcome was related to the length and apico-coronal location of the tears. We examined the radiographic CET related to the predisposing factors and the periodontal characteristics. Periapical x-rays taken between 2009 and 2017 were screened and 82 CET teeth among 46 subjects were included. A radio-opaque fragment along the root surface and the related periodontal and periapical bone loss were evaluated radiographically, and the gingival swelling and deep periodontal pocket were examined clinically. The demographic data, clinical, and radiographic findings were recorded and analyzed using the χ2 test. CETs were more prevalent in the incisors of males, aged ≥ 50 years. Single or multiple CETs occurred in the cervical and middle thirds more than the apical third of the roots. CETs presented with deep pockets, abscesses, and fistulae. In cervical CETs, the periodontal space widening and angular bone loss were more prevalent (p < 0.005), regardless of pulp vitality, root filling, and the crown status of the affected tooth and the antagonist. The apical CETs were associated with periapical lesions and loss of pulp vitality (p < 0.001). In conclusion, CETs can mimic periapical or periodontal lesions, which make their early diagnosis difficult. Therefore, CET should be considered as a differential diagnostic entity in isolated sites with rapid periodontal breakdown in elderly patients. Further research is required to examine whether the structural weakness of the cementum would cause multiple tears in the predisposed individuals.
Trichostatin A Protects Liver against Septic Injury through Inhibiting Toll-Like Receptor Signaling
김소진,박진숙,이도원,이선미 한국응용약물학회 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.4
Sepsis, a serious clinical problem, is characterized by a systemic inflammatory response to infection and leads to organ failure. Toll-like receptor (TLR) signaling is intimately implicated in hyper-inflammatory responses and tissue injury during sepsis. Histone deacetylase (HDAC) inhibitors have been reported to exhibit anti-inflammatory properties. The aim of this study was to investigate the hepatoprotective mechanisms of trichostatin A (TSA), a HDAC inhibitor, associated with TLR signaling pathway during sepsis. The anti-inflammatory properties of TSA were assayed in lipopolysaccharide (LPS)-stimulated RAW264.7 cells. Polymicrobial sepsis was induced in mice by cecal ligation and puncture (CLP), a clinically relevant model of sepsis. The mice were intraperitoneally received TSA (1, 2 or 5 mg/kg) 30 min before CLP. The serum and liver samples were collected 6 and 24-h after CLP. TSA inhibited the increased production of tumor necrosis factor (TNF)-α and interleukin (IL)-6 in LPS-stimulated RAW264.7 cells. TSA improved sepsis-induced mortality, attenuated liver injury and decreased serum TNF-α and IL-6 levels. CLP increased the levels of TLR4, TLR2 and myeloid differentiation primary response protein 88 (MyD88) protein expression and association of MyD88 with TLR4 and TLR2, which were attenuated by TSA. CLP increased nuclear translocation of nuclear factor kappa B and decreased cytosolic inhibitor of kappa B (IκB) protein expression, which were attenuated by TSA. Moreover, CLP decreased acetylation of IκB kinase (IKK) and increased association of IKK with IκB and TSA attenuated these alterations. Our findings suggest that TSA attenuates liver injury by inhibiting TLR-mediated inflammatory response during sepsis.