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      • SCOPUSKCI등재

        NP - 59 부신 신티그라피의 임상적 유용성에 관한 연구

        김덕규(Duk Kyu Kim) 대한핵의학회 1997 핵의학 분자영상 Vol.31 No.1

        N/A Laparoscopic cholecystectomy can be performed safely in most patients with symptomatic cholelithiasis. Preoperative evaluation should assess the potential problems that affect the performance of laparoscopic cholecystectomy. Hepatobiliary scintigraphy or oral cholecystography can assess the gallbladder function and nonvisualization of gall bladder usually indicates acute or severe chronic cholecystitis. The purpose of this study was to evaluate the role of preoperative hepatobiliary scintigraphy or oral cholecystography in predicting the performance of laparoscopic cholecystectomy. The study group consists of 176 patients who underwent both hepatobiliary scintigraphy with Tc-99m DISIDA and oral cholecystography within one month before laparoscopic cholecystectomy. Nonvisualization of gallbladder was defined as persistent nonvisualization of gall- bladder until 4 hours on hepatobiliary scintigraphy or 12 hours on oral cholecystography. Among 176 patients, gallbladder was not visualized in 38 patients on hepatobiliary scintigraphy and 41 patients on oral cholecystography, Concordance rate between hepatobiliary scintigraphy and oral cholecystography was 89.2%. The conversion rate to open cholocystectomy was significantly higher in patients with nonvisualization of gallbladder than in patients with gallbladder visualization(15.8% vs 2.9% on hepatobiliary scintigraphy, 12.2% vs 3.7% on oral cholecystography: p〈0.01 and p〈0.05 respectively). The operative complication rate was also significantly higher in patients with nonvisualization of gallbladder (13.2% vs 2.9% on hepatobiliary scintigraphy, 14.6% vs 2.2% on. oral cholecystography : p〈0.0l and p〈0.001, respectively). Similarly, operation time was significantly prolonged in patients with nonvisualization of gall bladder (88.8±41.9min vs 62.5±23.6min on hepatobiliary scintigraphy : p〈0.001, 89.4±41.3 min vs 61.8±22.8 min on oral cholecystography : p〈0.001). It is concluded that nonvisualization of gallblader on hepato biliary scintigraphy or oral cholecystography is a valuable preoperative clincal risk factor in predicting increased conversion rate to open cholecystectomy, increased operative complication and prolonged operation time.

      • KCI등재
      • KCI등재후보
      • 무선전화 시스템용 잡음억제회로의 설계

        문종규,김덕규,Moon, Jong-Kyu,Kim, Duk-Gyoo 대한전자공학회 2002 電子工學會論文誌 IE (Industry electronics) Vol.39 No.2

        본 논문에서는 무선전화 시스템의 잡음제거 방법을 제안한다. 구현회로는 압축기(Compressor), 신장기(Expender) 및 필터로 구성된다. 제안방법의 기본개념은 채널잡음을 방지하기 위해 전송전에 음성신호를 압축(Compress)하여 전송하고 원래의 신호를 복원하기 위해 전송신호의 역 비율로 신장(Expand)한다. 압축과 신장과정을 통해서 음성신호의 감쇠나 왜곡은 일어나지 않는다. 압축과정에서 압축기의 이득은 입력신호의 유효 다이나믹 영역과 신호대 잡음 비를 향상시키기 위해 음성신호의 포락선 레벨에 따라 자동적으로 제어된다. 압축비율은 음성신호의 제곱근(Root) 배로 압축한다. 압축된 신호는 신장기에서 음성신호의 제곱이 되게 신장하여 원래의 신호를 복원한다. 시뮬레이션을 통해 제안한 방법의 성능과 안정성을 검증하였다. In this paper, we present the design method of noise reduction circuit in telephonic system. The circuit consists of compressor, expander and a filter. The basic idea of a proposed method compresses the audible signal in order to mask the channel noise during transmission and then expand at the reverse rate the transmitted signal to naturally recover the original signal. Of course, there should be no distortion or other degradation of the audio itself in passing through companding(compress/expand) cycle. In the compressing process, the gain of compressor is automatically controlled by the envelope level of input signal in order to increase the effective dynamic range of input signal and to improve the signal to noise ratio. The compressed rate is the root time of a audible signal. The compressed signal should be expanded at the square time of the signal to recover a original signal. Simulation shows the proposed method improves the performance of the noise reduction of a channel noise as well as stability.?

      • 온도에 무관한 전압검출기의 바이어스 구현

        문종규,김덕규,Moon, Jong-Kyu,Kim, Duk-Gyoo 대한전자공학회 2002 電子工學會論文誌-SC (System and control) Vol.39 No.6

        본 논문에서는 전압검출기에 사용되는 온도에 무관한 검출 전압원을 제안한다. 검출 전압원이 절대온도 영도(Zero degree)에서 실리콘 밴드갭 전압의 m배가 되도록 설계한다. 검출 전압원의 온도계수는 트랜지스터 이미터-베이스 사이의 서로 다른 면적을 가진 다이오드에 생성된 비선형 전압인 ${\Delta}V_{BE}$의 오목한 온도계수와 트랜지스터 순방향 전압인 $V_{BE}$의 볼록한 비선형 온도계수의 합으로 다이오드의 온도계수를 적절히 선택함으로서 거의 제로의 온도계수를 실현한다. 또한 검출 전압원의 값이 ${\Delta}V_{BE}$, $V_{BE}$ 멀티플라이어 회로 및 저항을 이용하여 변화될 수 있도록 설계하였다. 제안한 검출 전압원의 성능을 평가하기 위해, $6{\mu}m$ 바이폴러 기술로 조립된 1.9V용 IC를 제작하여 검출 전압원의 동작특성과 온도계수를 측정하였다. 또한 검출 전압원의 값이 공정에 의해 변화되는 요인을 줄이기 위해 트리밍 기술, 이온 임플란테이션과 이방성 에칭을 도입하였다. 제작된 IC에서 검출 전압원은 -30$^{\circ}C$~70$^{\circ}C$의 온도범위에서 29ppm/$^{\circ}C$의 안정된 온도계수를 얻을 수 있었다. 그리고 전압검출기의 소비전류는 1.9V 공급전압에서 $10{\mu}A$이다. In this paper, we propose a temperature independent the detective voltage source in voltage detector. The value of a detective voltage source is designed to become m times of silicon bandgap voltage at zero absolute temperature. By properly choosing the temperature coefficient of diode, the temperature coefficient of a concave voltage nonlinearities generated by the ${\Delta}V_{BE}$ section of diode between base and emitter of transistors with a different area can be summed with convex nonlinearities the $V_{BE}$ voltage to achieve the near zero temperature coefficient of the detective voltage source. We designed that the value of a detective voltage can be varied by ${\Delta}V_{BE}$, the $V_{BE}$multiplier circuit and resistor. In order to verify the performance of a proposed detective voltage source, we manufactured the voltage detector IC for 1.9V which is fabricated in $6{\mu}m$ Bipolar technology and measured the operating characteristics, the temperature coefficient of a detective voltage. To reduce the deviation of a detective voltage in the IC process step, we introduced a trimming technology, ion implantation and an isotropic etching. In manufactured IC, the detective voltage source could achieve the stable temperature coefficient of 29ppm/$^{\circ}C$ over the temperature range of -30$^{\circ}C$ to 70$^{\circ}C$. The current consumption of a voltage detector constituted by the proposed detective voltage source is $10{\mu}A$ from 1.9V-supply voltage at room temperature.

      • KCI등재

        증례 : 내분비-대사 ; 다발·양측성 신세포암이 발병한 폰히펠린다우병 환자의 고주파 절제술

        문상이 ( Sang Yi Moon ),김동현 ( Dong Hyun Kim ),정의한 ( Eui Han Jung ),박소영 ( So Young Park ),박미경 ( Mi Kyung Park ),김덕규 ( Duk Kyu Kim ),서성환 ( Sung Hwan Suh ) 대한내과학회 2014 대한내과학회지 Vol.87 No.5

        폰히펠-린다우병의 신세포암의 표준치료는 콩팥 단위 보존 수술이지만 다발성, 양측성 및 재발을 잘한다는 특성으로 인해 여러 가지 한계가 존재하여, 최근에는 고주파 절제술을 통한 신세포암의 치료가 소개되고 있다. 저자들은 폰히펠-린 다우병 환자가 다발성, 양측성 신세포암을 진단 후 순차적인 고주파 절제술을 통한 성공적인 치료의 1예를 문헌고찰과 함께 보고하고자 한다. Von Hippel-Lindau (VHL) disease is an inherited, autosomal dominant syndrome that manifests as a variety of benign and malignant tumors in various organs. Notably, renal cell carcinoma (RCC) in patients with VHL disease tends to be multifocal and bilateral, and tends to recur or new tumors develop after removal. Radiofrequency ablation (RFA) has recently been introduced as a minimally invasive treatment for small hereditary RCCs with a low complication rate and a minimal decrease in renal function. We present a case of successful RFA of multiple bilateral RCCs in a 24-year-old female with VHL. Computed tomography (CT) of the abdomen revealed multiple bilateral RCCs. The patient received sequential RFA for the bilateral RCCs, resulting in a complete response. At the time of writing, there was no sign of recurrence or renal failure. In conclusion, percutaneous RFA is a promising treatment for VHL patients who cannot undergo surgery, with excellent treatment outcomes and minimal change in renal function. (Korean J Med 2014;87:603-608)

      • SCOPUSKCI등재

        만성활동간염의 HBsAg 양성율과 임상적 고찰

        유방현(Bang Hyun Liu),김호균(Ho Kyun Kim),김덕규(Duk Kyu Kim),배광훈(Gwang Hoon Bae),김두연(Ku Yeun Kim),박혜경(Hae Kyung Park) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.1

        N/A HBsAg positivity and clinical studies in 49 cases with chronic active hepatitis, were carried out at Busan National University Hospital, from March 1978 to November 1981 The results were as follows: 1) Incidence of HBsAg was 67. 3% in cases with chronic active hepatitis. Sex distribution was 30 cases in male among HBsAg positive group and 19 cases in male among negative group. Mean age of HBsAg positive group was 35% years and negative group 43. 9 years, and there was a significant difference in mean age between both groups. 2) There was a history of acute hepatitis in 34 cases(69.4%), The interval between the acute attack and the diagnosis of chronic active hepatitis averaged 21.7 months. 3) In chemical liver function tests, SGPT and TTT were significantly increased in HBsAg positive group as compared with negative group, while SGOT, alkaline phosphatase and serum bilirubin showed no significant differences between both groups. 4) Immunoglobulin G and A were slightly increased in HBsAg negative group as compared with positive group, but there were no significant differences between both groups. 5) Jn 23 cases(13 cases with HBsAg positive and 10 cases with negative) who had been folloived for average of 20 months, incidences of improved, stabilized and aggravated cases showed no significant differences between HBsAg positive and negative group. But incidence of relapsed cases was significantly higher in HBsAg positive group than negative group.

      • KCI등재후보

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