http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
김광곤,진성호,이병주 대한내분비학회 2013 Endocrinology and metabolism Vol.28 No.3
Background: Reduced appetite and body weight loss are typical symptoms of inflammatory diseases. A number of inflammatory stimuli are responsible for the imbalance in energy homeostasis, leading to metabolic disorders. The herpes virus entry mediator (HVEM) protein plays an important role in the development of various inflammatory diseases, such as intestinal inflammation and diet-induced obesity. However, the role of HVEM in the brain is largely unknown. This study aims to investigate whether HVEM signaling in the brain is involved in inflammation-induced anorexia and body weight loss. Methods: Food intake and body weight were measured at 24 hours after intraperitoneal injection of lipopolysaccharide (LPS) or intracerebroventricular injection of recombinant mouse LIGHT (also called tumor necrosis factor receptor superfamily 14, TNFSF14), an HVEM ligand, into 8- to 10-week-old male C57BL/6 mice and mice lacking HVEM expression (HVEM-/-). We also assessed LPS-induced change in hypothalamic expression of HVEM using immunohistochemistry. Results: Administration of LPS significantly reduced food intake and body weight, and moreover, increased expression of HVEM in the hypothalamic arcuate nucleus. However, LPS induced only minor decreases in food intake and body weight in HVEM-/-mice. Administration of LIGHT into the brain was very effective at decreasing food intake and body weight in wild-type mice,but was less effective in HVEM-/- mice. Conclusion: Activation of brain HVEM signaling is responsible for inflammation-induced anorexia and body weight loss.
김광곤(Gwang-Gon Kim),서순석(Soon-Suk Seo),박민영(Min-Young Park) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.7
적정한 예정가격이란 수주자가 전기공사를 정상적으로 시행하여 발주자가 기대하는 품질과 공사기간를 보장하면서 적정한 이윤을 확보할 수 있는 금액을 말하며, 이는 계약행위의 원활한 이행에 기본이 되는 것으로 그 중요성은 매우 크다. 따라서 현행 전기공사 원가계산에 이용되고 있는 간접공사비 제비율 적용기준에 대하여 전반적으로 분석하되 법령에 규정된 제비율적용 항목을 제외한 간접노무비, 기타경비, 일반관리비, 이윤의 제비율에 대한 문제점을 분석하고, 분석자료에 근거하여 합리적인 전기공사 간접공사비 제비율 적용기준을 제시 하고자 한다.
김광곤(Gwang-Gon Kim),서순석(Soon-Suk Seo),박민영(Min-Young Park) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.4
The important matter of public construction work is to perform which is estimated cost on reasonable electric work. A historical construction cost should be fixed to deter mine the reasonable cost. Because a faulty construction and waste budget has been occurred on the decision of the estimated cost. At present, a structure of historical cost accumulation is the contract statement of items, Therefor it's bring a continued decline in a historical cost. In this paper, we study the improvements of calculating reasonable costs to overcome a structure of continued decline and to guarantee estimated cost on reason able electric work.