특집Ⅱ: 아버지 죽이기: 피학대아동을 위한 정당방위 전략;아버지 죽이기: 피학대아동을 위한 정당방위 전략

곽은비 서울대학교 BK21 법학연구단 공익인권법연구센터 2014 공익과 인권 Vol.14 No.-

일부 치과병원 계속구강관리 프로그램 대상자의 와타나베 칫솔질에 의한 치은출혈 변화

곽은비,김혜진 국제차세대융합기술학회 2024 차세대융합기술학회논문지 Vol.8 No.3

연구는 경남 양산시 Y치과병원 내 계속구강관리실에 구강관리 프로그램을 받는 성인 35명에게 칫솔질 교 육 및 와타나베 칫솔질을 2주 간격으로 5회 시행 후 치면세균막 지수 변화와 와타나베 칫솔질에 의한 치은출혈의 변화를 확인하고 반복적인 구강관리교육의 효과 및 와타나베 칫솔질의 효과에 대한 근거를 뒷받침하여 치과 현장 에서 활용 가능한 전문가 관리의 기초자료가 되고자 한다. 연구 방법 및 연구목적에 대해 충분한 설명을 한 후 동 의를 구하여 설문조사 및 구강관리 검사를 시행하였으며, SPSS statisctics를 이용하여 계속구강관리 프로그램 회 차별 치면세균막 관리 변화 및 와타나베 치은출혈 변화는 RM-ANOVA로 분석하였다. 연구 결과 계속구강관리 프로그램 1회부터 5회까지 치면세균막 지수와 치은출혈의 변화를 반복 측정하였을 때 회차를 거듭할수록 대상자 의 구강건강관리 능력이 개선되었으며, 치은 출혈량이 감소되었음을 확인할 수 있었다(p<.05). 향후 치과 내원 고 객의 구강건강 유지 및 증진을 위하여 치과 현장에서 실질적으로 활용 가능한 계속구강관리 프로그램에 치과위생 사가 지속적으로 개입하는 것이 바람직할 것으로 사료된다. This study aimed to determine the changes in gingival bacterial membrane index and gingival bleeding caused by Watanabe toothbrushing after repeated oral care education and Watanabe toothbrushing five times at 2-week intervals in 35 adults receiving oral care programs in the Continuous Oral Care Unit at Y Dental Hospital in Yangsan, Gyeongnam, and to provide evidence for the effectiveness of repeated oral care education and Watanabe toothbrushing, which can be used as a basis for professional management in the dental field. After fully explaining the study method and purpose, consent was obtained and surveys and oral care examinations were conducted, and changes in gingival bacterial film management and changes in Watanabe gingival bleeding were analyzed by RM-ANOVA using SPSS statisctics. The results of the study showed that the subjects' oral health care ability improved and the amount of gingival bleeding decreased over time (p<.05) when repeatedly measuring the changes in gingival bacterial film index and gingival bleeding from the first to the fifth session of the continuous oral care program. In the future, it is recommended that dental hygienists should be involved in continuous oral care programs that can be practically used in dental offices to maintain and improve the oral health of dental clients.

Association of GnRH1 Polymorphisms with Rheumatoid Arthritis in a Korean Female

김유미,한계영,곽은비,전완주,김성수,이희제 대한정형외과학회 2010 대한정형외과학회지 Vol.45 No.5

Purpose: Rheumatoid arthritis (RA) is a common, chronic inflammatory arthritis that develops most often in women. Gonadal hormones may account for the sexual dimorphism in the immune response and for the greater incidence of autoimmune disease in females. Gonadotrophin- releasing hormone (GnRH), one of the gonadal hormones, plays an important role in immune system modulation. This study examined the effects of single nucleotide polymorphisms (SNP) in GnRH on gender differences in the pathophysiology of RA. Materials and Methods: The presence of SNPs rs2659590, rs2321248, rs6186, rs6185, and rs2321049 in the human GnRH1 gene was confirmed in Korean RA patients by Taqman® SNP genotyping assays. A total of 153 unrelated female, Korean RA patients and 96 female Korean controls participated. Results: There were no significant associations between GnRH1 polymorphisms and RA. However, we found that the rs2659590, rs6185 and rs2321248 polymorphism might be associated with a susceptibility to aberrantly high erythrocyte sedimentation rates in female RA patients. Conclusion: Additional studies, with a larger number of patients and in different populations will be required to assess whether GnRH1 polymorphisms and these haplotypes could be used as susceptibility or resistance markers in RA. To our knowledge, this study is the first to analyze associations between SNPs of GnRH1 and RA. Purpose: Rheumatoid arthritis (RA) is a common, chronic inflammatory arthritis that develops most often in women. Gonadal hormones may account for the sexual dimorphism in the immune response and for the greater incidence of autoimmune disease in females. Gonadotrophin- releasing hormone (GnRH), one of the gonadal hormones, plays an important role in immune system modulation. This study examined the effects of single nucleotide polymorphisms (SNP) in GnRH on gender differences in the pathophysiology of RA. Materials and Methods: The presence of SNPs rs2659590, rs2321248, rs6186, rs6185, and rs2321049 in the human GnRH1 gene was confirmed in Korean RA patients by Taqman® SNP genotyping assays. A total of 153 unrelated female, Korean RA patients and 96 female Korean controls participated. Results: There were no significant associations between GnRH1 polymorphisms and RA. However, we found that the rs2659590, rs6185 and rs2321248 polymorphism might be associated with a susceptibility to aberrantly high erythrocyte sedimentation rates in female RA patients. Conclusion: Additional studies, with a larger number of patients and in different populations will be required to assess whether GnRH1 polymorphisms and these haplotypes could be used as susceptibility or resistance markers in RA. To our knowledge, this study is the first to analyze associations between SNPs of GnRH1 and RA.

부산지역 일부 학교 내 구강보건교육 경험에 따른 간식섭취 및 칫솔질 행태에 연구: 초등학교 4학년을 중심으로

도윤정,박규정,곽은비,박혜영,김혜진 한국학교·지역보건교육학회 2019 한국학교지역보건교육학회지 Vol.20 No.3

Objectives: This study was conducted to investigate the snack intake and brushing behavior according to the oral health education experience in some schools in Busan, and to investigate whether the oral health education experience affects the snack intake and brushing behavior. Methods: This study surveyed the entire fourth grade of elementary school in two districts by participating in university-linked oral health education activities run under the jurisdiction of the education office business to examine changes in the behavior of elementary school students in their snack intake and toothbrush. The survey was conducted on oral health education in elementary schools, prior oral health education experience before and after the activity, whether or not the brushing classroom was operated, and contents related to eating snacks and brushing behaviors. Result: Among the general characteristics of some schools in Busan, 69.9% of students have experience in oral health education and 30.1% of people have no experience in oral health education. 20.0%, 16.3% were 'normal' and 63.7% were 'helpful'. The brushing behavior according to the oral health education was 44.9% in the number of brushings, 44.9% in the number of brushings, 45.7% in 2-3 minutes in the time of brushing, 41.2% in the brushing method by sweeping the brush up and down. In the daily brushing period, 'after breakfast' was the highest at 72.3%, and the parent's brushing instruction was 'to lead' at 65.1%. The amount of sugar in subjective snacks was the highest with 60.6% of sugar content, and the parents had the highest level of 52.2% for parents' snack intake. This result was more significant than the students without oral health education experience. Conclusion: Based on the results of this study, the number and time of brushing, the method and timing of brushing according to the experience of oral health education. Students who had oral health education experience higher than those who did not have oral health education, but had a lower tendency to brush after lunch at school and before going to bed. For better oral health, the effect of oral health education will be better if the school has more systematic toothbrushing at lunch time and parental guidance at home.

입원환자를 대상으로 간호사의 구강간호 실태 및 치과위생사의 협력진료 요구도

이태림,임나연,권수희,차은숙,최서정,정금비,곽은비 한국구강보건과학회 2023 한국구강보건과학회지 Vol.11 No.3

Objectives: The aim of this study is to serve as basic data to prove the need for dental hygienists through the cooperation of dental hygienists, who are oral care experts. Methods: A survey was conducted on nurses who perform nursing work in general hospitals and university hospital wards located in Busan, and Ulsan. Results: As a result of the oral nursing performance of the subjects with educational experience was higher on average than the subjects without educational experience, which was statistically significant(p<0.05). Conclusions: It was found that educational experience had an effect on performing oral care. In order to improve the quality of oral care the participation of dental hygienists specializing in oral care is required, and it is thought that systematic education on oral care of nursing personnel is necessary

시청자 반응을 통한 영상 콘텐츠 객체의 감정 영향력 측정과 평가

이소정(Sojeong Lee),손규진(Gyujin Son),신희원(HeeWon Shin),김혜린(Hyerin Kim),곽서현(SeoHyun Kwag),김영민(YoungMin Kim),남은비(Eunbi Nam),김다혜(DaHye Kim),김윤희(YoonHee Kim) 한국정보과학회 2020 한국정보과학회 학술발표논문집 Vol.2020 No.7

Association of GnRH1 Polymorphisms with Rheumatoid Arthritis in a Korean Female

Yu Mi Kim(김유미),Kye Young Han(한계영),Eun Bi Kwak(곽은비),Wanjoo Chun(전완주),Sung Soo Kim(김성수),Hee Jae Lee(이희제) 대한정형외과학회 2010 대한정형외과학회지 Vol.45 No.5

목적: 류마티스 관절염(RA)의 병태생리에 대해 아직 명확하게 밝혀져 있지 않으나 일부의 경우 유전적 요인이 류마티스 관절염의 발생에 영향을 주는 것으로 알려져 있다. 역학조시 결과 여성이 남성보다 류마티스성 관절염의 유병률이 3배 정도 높다. Gonadal 호르몬들은 면역체계나 자가면역질환에서 성에 따른 이형을 나타내는데 영향을 주는 것으로 알려져 있다. 이 가운데 gonadotrophin-releasing hormone (GnRH)는 면역 시스템을 조절하는 데도 중요한 역할을 한다. 따라서,GnRH가 류마티스 관절염에서 성적 차이를 나타내는데 중요한 역할을 할 수 있으며 이를 증명하기 위해 GnRH1 유전자를 후보 유전자로 선택하고 이들 유전자 내의 단일염기다형성(SNP)을 분석함으로써,RA와 GnRHl 유전자 다형성과의 연관성에 대해 연구하고자 하였다. 대상 및 방법: 153명의 RA 여성 환자와 96명의 정상 대조군을 대상으로, GnHR1 유전자 내의 5개의 SNP, rs2659590, rs2321248, rs6186, rs6185, rs2321049의 유전자형과 대립유전자형의 빈도를 비교 분석하였다. 또한 RA 환자들을 erythrocyte sedimentation rate (ESR)과 골 미란 유무에 따라 나누고 GnRH1 SNP과의 연관성을 확인하였다. 결과: 한국인 여성 RA 환자들과 정상군들 사이에서 GnRH1 SNP들의 유전자형과 대립유전자들의 빈도는 유의한 차이가 없었다. 하지만, rs2659590, rs6185, rs2321248에서 ESR이 30 이상인 환자와 30 미만 환자 사이에 로지스퇴 회귀 분석 결과 유의한 상관관계가 나타났다. 하지만, 골 미란 유무는 연관성이 없었다. 결론: 본 연구에서 RA와 GnRH1 유전자 다형성 사이의 연관성은 보여주지 못하였지만, ESR의 수치와 GnRH1 유전자 다형성 간에 연관성을 보였다. 비록 그 수가 적어 제한적인 의미를 가질 수 있으나 처음으로 GnRH1 유전자의 다형성과 RA환자의 ESR 간의 연관 가능성을 시사하는데 의의가 있다. Purpose: Rheumatoid arthritis (RA) is a common, chronic inflammatory arthritis that develops most often in women. Gonadal hormones may account for the sexual dimorphism in the immune response and for the greater incidence of autoimmune disease in females. Gonadotrophin- releasing hormone (GnRH), one of the gonadal hormones, plays an important role in immune system modulation. This study examined the effects of single nucleotide polymorphisms (SNP) in GnRH on gender differences in the pathophysiology of RA. Materials and Methods: The presence of SNPs rs2659590, rs2321248, rs6186, rs6185, and rs2321 049 in the human GnRH1 gene was confirmed in Korean RA patients by Taqman" SNP genotyping assays A total of 153 unrelated female, Korean RA patients and 96 female Korean controls participated. Results: There were no significant associations between GnRH1 polymorph isms and RA. However, we found that the rs2659590, rs6185 and rs2321248 polymorphism might be associated with a susceptibility to aberrantly high erythrocyte sedimentation rates in female RA patients. Conclusion: Additional studies, with a larger number of patients and in different populations will be required to assess whether GnRH1 polymorph isms and these haplotypes could be used as susceptibility or resistance markers in RA. To our knowledge, this study is the first to analyze associations between SNPs of GnRH1 and RA.