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      • SCOPUSKCI등재

        심실내 전도장애 환자에서의 99mTc-RBC Gated Blood-Pool Scintigraphy 을 통한 Phase Image Analysis

        이강욱(Kang Wook Lee),곽병수(Byeng Su Kwak),최시완(Si Wan Choi),강승식(Seung Sik Kang),박기남(Ki Nam Park),전은석(Eun Seok Jeon),박종훈(Chong Hun Park) 대한핵의학회 1994 핵의학 분자영상 Vol.28 No.1

        N/A It is known that the normal His-Purkinje system provides for nearly synchronous activation of right (RV) and left (LV) ventricles. When His-Purkinje conduction is abnorrnal, the resulting sequenee of ventricular contraction must be correspondingly abnormal. These abnormal mechanical consequences were difficult to demonstrate because of the complexity and the rapidity of its events. To determine the relationship of the phase changes and the abnormalities of ventricular conduction, we performed phase image analysis of Tc-RBC gated bJood pool scintigrams in patients with intraventricular conduction disturbances (24 complete left bundle branch block (C-LBBB), 15 complete right bundle branch block (C-RBBB), 13 Wolff-Parkinson-White syndrome (WPW), 10 controls). The results were as follows; 1) The ejection fraction (EF), peak ejection rate (PER), and peak filling rate (PFR) of LV in gated blood pool scintigraphy (GBPS) were significantly lower in patients with C-LBBB than in controls (44.4 +- 13.9% vs 69.9 +- 4.2%, 2.48 +- 0.98 vs 3.51 +- 0,62, 1.76 +- 0.71 vs 3.38 +- 0.92, respectively, p<0.05). 2) In the phase angle analysis of LV, Standard deviation (SD), width of half maximum of phase angle (FWHM), and range of phase angle were significantly increased in patients with C-LBBB than in controls (20.6+ 18.1 vs S.6+ I.8, 22. 5+ 9.2 vs 16.0+ 3.9, 95.7+ 31.7 vs 51.3+5.4, respectively, p< 0.05). 3) There was no significant difference in EF, PER, PFR between patients with the WolffParkinson-White syndrome and controls. 4) Standard deviation and range of phase angle were significantly higher in patients with WPW syndrome than in controls (10.6+2.6 vs 8.6+1.8, p<0.05, 69.8+11.7 vs 51.3+5 4, p < 0.001, respectively), however, there was no difference between the two groups in full width of half maxirnurn. 5) Phase image analysis revealed relatively uniform phase across the both ventriles in patients with normal conduction, but markedly delayed phase in the left ventricle of patients with LBBB. 6) ln 13 cases of WPW syndrome, the site of preexcitation could be localized in 10 cases (77%) by phase image analysis. Therefore, it can be concluded that phase irnage analysis can provide an accurate noninvasive method to detect the mechanical consequences of a wide variety of abnormal

      • 심실전도장애환자에서 위상각 분석의 의의

        전은석,곽병수,이강욱,박종훈 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        It is known that the normal His-Purkinje system provides for nearly synchronous activation of the right and left ventricles. When this His-Purkinje conduction is abnormal, the resulting sequence of the both ventricular contraction should be changed. These abnormal mechanical consequences resulting from abnormal conduction system have been difficult to demonstrate because these are very rapid and complex. We evaluate the phase angle analysis using radionuclide gated blood pool scan(GBP) as a quantitative method which can determine the asynchronous contraction of left ventricule in patients with complete left bundle branch block(C-LBBB, 20 cases) and complete right bundle branch block(C-RBBB, 15 cases). The results as follows : 1) The ejection fractions, peak ejection rates, in GBP were significantly decraesed in patients with C-LBBB compared with controls(10 cases, 70± 4.2 vs 44± 13.9%, 3.51± 0.62 vs 2.48± 0.98, p<0.05 by t-test respectively). The peak filling rates were also decreased in patients with C-LBBB(3.38± 0.92 vs 1.76± 0.71, 1A.05). 2) In the phase angle analysis, the standard deviations and the width of half maximum of phase angle were significantly increased in patients with C-LBBB(8.6± 1.8 vs 20.6± 18.1, 16.0± 3.9 vs 22.5± 9.2, p<0.05 by t-test respectively). And the ranges of phase angle were also increased in C-LBBB(51.3± 5.4 vs 95.7± 31.7, p<0.05). 3) But there were no significant differences in GBP and phase angle analysis between patients with C-RBBB and controls. As the results above, it can be concluded that the phase angle analysis can provide an accurate noninvasive method to detect the asynchronous contraction in patients with abnormal intraventricular electrical activation.

      • KCI등재후보

        우심실에 발생한 Synovial Sarcoma 1 예

        최용석,이영,박기남,전은석,김삼용,곽병수,최시완,박종훈,강승식,김백수,김응중,조문준 대한내과학회 1994 대한내과학회지 Vol.47 No.2

        Primary tumors of the heart are extremely rare. About twenty-five percent of primary heart tumors are malignant. We experienced a case of synovial sarcoma. A 48-year-old man was admitted to CNUH with Dyspnea on exertion and chest pain. Preoperative diagnosis of the cardiac tumor was made on the basis of 2-dimensional echocardiography. A cardiac synovial sarcoma was resected unsuccessfully, Pathologic diagnosis was synovial sarcoma. The patient was recommended to have combined multimodality treatment including postoperative chemotherapy regimen and Radiotherapy. He was dead 12 months after resection because of heart failure.

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